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The map label for this gene is cobO [H]

Identifier: 121638729

GI number: 121638729

Start: 3111507

End: 3112130

Strand: Reverse

Name: cobO [H]

Synonym: BCG_2869c

Alternate gene names: 121638729

Gene position: 3112130-3111507 (Counterclockwise)

Preceding gene: 121638730

Following gene: 121638728

Centisome position: 71.14

GC content: 65.22

Gene sequence:

>624_bases
ATGCCGCAGGGCAATCCGCTCGCAGTGCCCAACGATGGCCTGACCACCCGGGCCCGGCGCAACATGCCGATACTGGCGGT
ACACACCGGTGAAGGCAAAGGAAAATCGACCGCGGCGTTCGGAATGGCGTTGCGGGCGTGGAACGCTGGTCTGGACATCG
CGGTGTTTCAGTTTGTCAAGAGCGCTAAGTGGAAAGTGGGTGAGGAGGCGGCGTTTCGTCAACTGGGCCGGCTGCACGAC
CAGCACGGGATCGGCGGAGCGGTGGAGTGGCACAAGATGGGTGCGGGCTGGTCCTGGACACGTACGTCTCGCAAGGCCGG
CACCGACGTCGATCGTGCGGCCGCGGCGGCGGACGGTTGCGCCGAGATCGCGCTCCGGCTGGCCACGCAACGTCACGACT
TCTATCTGCTGGACGAGTTCACCTACCCACTGAAGTGGGGTTGGCTCGACGTCGACGAAGTCGTCGATGTCCTGCGAGCC
CGGCCTGGCCATCAGCATGTGGTGATCACCGGGCGAGACGCACCCCAGCGGTTGGTTGCGGCCGCCGATCTGGTGACCGA
GATGACCAAGGTGAAGCACCCGATGGATGCGGGCCGCAAGGGGCAGAAGGGCATCGAGTGGTGA

Upstream 100 bases:

>100_bases
GTCAGCTGGGTGCGCCGGTGGTTCGGTTGGAGCAGTTGCACGCGGATTATCTAGTGCATGCCGTGCGTGGCGTGGCTTGA
CGATGGATAGGTAACCACAC

Downstream 100 bases:

>100_bases
TGCGGGTATCCGCGGTGGCCGTCGCCGCGCCTGCGTCGGGCAGCGGTAAGACCACGATCGCGACGGGCTTGATCGGAGCG
CTGCGGCAGGCCGGTCACAC

Product: cob(I)yrinic acid a,c-diamide adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 207; Mature: 206

Protein sequence:

>207_residues
MPQGNPLAVPNDGLTTRARRNMPILAVHTGEGKGKSTAAFGMALRAWNAGLDIAVFQFVKSAKWKVGEEAAFRQLGRLHD
QHGIGGAVEWHKMGAGWSWTRTSRKAGTDVDRAAAAADGCAEIALRLATQRHDFYLLDEFTYPLKWGWLDVDEVVDVLRA
RPGHQHVVITGRDAPQRLVAAADLVTEMTKVKHPMDAGRKGQKGIEW

Sequences:

>Translated_207_residues
MPQGNPLAVPNDGLTTRARRNMPILAVHTGEGKGKSTAAFGMALRAWNAGLDIAVFQFVKSAKWKVGEEAAFRQLGRLHD
QHGIGGAVEWHKMGAGWSWTRTSRKAGTDVDRAAAAADGCAEIALRLATQRHDFYLLDEFTYPLKWGWLDVDEVVDVLRA
RPGHQHVVITGRDAPQRLVAAADLVTEMTKVKHPMDAGRKGQKGIEW
>Mature_206_residues
PQGNPLAVPNDGLTTRARRNMPILAVHTGEGKGKSTAAFGMALRAWNAGLDIAVFQFVKSAKWKVGEEAAFRQLGRLHDQ
HGIGGAVEWHKMGAGWSWTRTSRKAGTDVDRAAAAADGCAEIALRLATQRHDFYLLDEFTYPLKWGWLDVDEVVDVLRAR
PGHQHVVITGRDAPQRLVAAADLVTEMTKVKHPMDAGRKGQKGIEW

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=196, Percent_Identity=37.7551020408163, Blast_Score=112, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 22727; Mature: 22596

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQGNPLAVPNDGLTTRARRNMPILAVHTGEGKGKSTAAFGMALRAWNAGLDIAVFQFVK
CCCCCCCCCCCCCCCCHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHH
SAKWKVGEEAAFRQLGRLHDQHGIGGAVEWHKMGAGWSWTRTSRKAGTDVDRAAAAADGC
HHCCCCCHHHHHHHHHHHHHHCCCCCCEEHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHH
AEIALRLATQRHDFYLLDEFTYPLKWGWLDVDEVVDVLRARPGHQHVVITGRDAPQRLVA
HHHHHHHHHCCCCEEEEECCCCCEEECCCCHHHHHHHHHCCCCCCEEEEECCCCHHHHHH
AADLVTEMTKVKHPMDAGRKGQKGIEW
HHHHHHHHHHHCCCHHCCCCCCCCCCC
>Mature Secondary Structure 
PQGNPLAVPNDGLTTRARRNMPILAVHTGEGKGKSTAAFGMALRAWNAGLDIAVFQFVK
CCCCCCCCCCCCCCCHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHH
SAKWKVGEEAAFRQLGRLHDQHGIGGAVEWHKMGAGWSWTRTSRKAGTDVDRAAAAADGC
HHCCCCCHHHHHHHHHHHHHHCCCCCCEEHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHH
AEIALRLATQRHDFYLLDEFTYPLKWGWLDVDEVVDVLRARPGHQHVVITGRDAPQRLVA
HHHHHHHHHCCCCEEEEECCCCCEEECCCCHHHHHHHHHCCCCCCEEEEECCCCHHHHHH
AADLVTEMTKVKHPMDAGRKGQKGIEW
HHHHHHHHHHHCCCHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]