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The map label for this gene is PE_PGRS44 [H]

Identifier: 121638476

GI number: 121638476

Start: 2885998

End: 2887638

Strand: Direct

Name: PE_PGRS44 [H]

Synonym: BCG_2614

Alternate gene names: 121638476

Gene position: 2885998-2887638 (Clockwise)

Preceding gene: 121638475

Following gene: 121638480

Centisome position: 65.97

GC content: 73.07

Gene sequence:

>1641_bases
ATGTCGTTTGTCACGGCAGCTCCAGAGATGCTGGCGACGGCGGCGCAGAATGTCGCGAATATCGGCACATCGCTGAGTGC
GGCAAACGCGACGGCAGCGGCGTCCACGACCTCGGTGCTGGCGGCCGGAGCCGACGAGGTATCGCAGGCTATCGCAAGGC
TGTTCAGTGATTACGCCACGCACTATCAGTCGCTGAACGCTCAAGCCGCGGCATTTCATCACAGCTTCGTGCAAACGTTG
AACGCCGCCGGTGGCGCCTATTCGAGCGCCGAGGCGGCCAACGCTTCGGCGCAGGCGTTGGAACAGAATCTGTTGGCCGT
GATCAATGCGCCCGCCCAGGCGTTGTTCGGGCGTCCCCTGATCGGCAATGGCGCGAATGGAACAGCGGCCAGCCCCAACG
GCGGTGATGGTGGGATTTTGTACGGCAACGGCGGCAACGGCTTCTCCCAAACGACCGCCGGGGTGGCCGGCGGCGCCGGT
GGTTCCGCGGGCCTGATCGGCAACGGCGGCAATGGTGGCGCCGGTGGGGCCGGTGCTGCCGGCGGGGCCGGCGGCGCCGG
CGGATGGCTGCTCGGCAACGGTGGCGCCGGCGGTCCCGGCGGCCCAACGGACGTTCCTGCCGGCACAGGTGGAGCCGGCG
GGGCCGGCGGCGACGCCCCATTGATCGGCTGGGGCGGCAACGGCGGGCCCGGCGGTTTCGCTGCTTTTGGAAACGGTGGG
GCCGGCGGCAACGGCGGCGCCAGCGGTTCGCTCTTTGGCGTCGGCGGCGCCGGCGGCGTCGGCGGATCGAGCGAAGACGT
CGGCGGCACCGGCGGGGCCGGCGGCGCTGGCCGCGGTCTATTCCTTGGCCTGGGCGGTGATGGCGGCGCCGGCGGCACCA
GCAACAACAACGGCGGTGACGGTGGCGCCGGCGGCACCGCGGGAGGTCGATTGTTCAGCCTGGGCGGTGACGGTGGCAAC
GGTGGTGCCGGTACCGCAATCGGATCCAACGCCGGTGACGGTGGCGCCGGCGGTGACAGCAGCGCCCTGATCGGCTACGC
CCAGGGCGGCTCCGGCGGCCTCGGCGGCTTCGGCGAAAGTACCGGCGGCGACGGCGGCCTGGGCGGCGCCGGCGCTGTGC
TCATCGGCACGGGCGTCGGCGGTTTCGGCGGCCTCGGTGGCGGCTCCAACGGCACCGGGGGCGCGGGCGGCGCGGGCGGC
ACGGGCGCCACGCTGATCGGCCTGGGCGCCGGCGGCGGCGGCAGCATCGGCGGGTTCGCCGTCAACGTGGGCAACGGCGT
CGGCGGTCTGGGCGGCCAGGGCGGCCAGGGCGCCGCGCTGATCGGCCTGGGCGCCGGCGGTGCCGGCGGTGCCGGCGGCG
CCACAGTCGTTGGACTTGGTGGCAATGACGGTGACGGCGGTGACGGTGGCGGCCTGTTTAGTATCGGCGTCGGCGGGGAC
GGCGGCAACGCCGGCAACGGCGCCATGCCTGCCAATGGCGGCAACGGCGGCAACGCCGGGGTCATTGCCAACGGCTCCTT
TGCCCCGTCGTTCGTCGGCTTCGGCGGCAACGGCGGCAACGGCGTCAATGGCGGCACCGGCGGCACCGGCGGCAGCGGCG
GGATCCTTTTTGGCGCCAACGGCGCGAACGGACCGTCGTAG

Upstream 100 bases:

>100_bases
GAAGCGCGAAAAATGGCAGACCCCGACGGAGGCCCTCTGAAAGAGTCTTGATCATCAGGGCGCGTGACATGTGTCACATG
ACGGGTTGGGAGGGTGGCTG

Downstream 100 bases:

>100_bases
CGGGTCCTCCAGCGCACTACTCGAACAACCCCGGTTGACTCGCTCCGACCGGTGGCGTCATGCCCAGGTGCGTCCAGGCC
AGGGCGGTGGCCACCCGGCC

Product: PE-PGRS family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 546; Mature: 545

Protein sequence:

>546_residues
MSFVTAAPEMLATAAQNVANIGTSLSAANATAAASTTSVLAAGADEVSQAIARLFSDYATHYQSLNAQAAAFHHSFVQTL
NAAGGAYSSAEAANASAQALEQNLLAVINAPAQALFGRPLIGNGANGTAASPNGGDGGILYGNGGNGFSQTTAGVAGGAG
GSAGLIGNGGNGGAGGAGAAGGAGGAGGWLLGNGGAGGPGGPTDVPAGTGGAGGAGGDAPLIGWGGNGGPGGFAAFGNGG
AGGNGGASGSLFGVGGAGGVGGSSEDVGGTGGAGGAGRGLFLGLGGDGGAGGTSNNNGGDGGAGGTAGGRLFSLGGDGGN
GGAGTAIGSNAGDGGAGGDSSALIGYAQGGSGGLGGFGESTGGDGGLGGAGAVLIGTGVGGFGGLGGGSNGTGGAGGAGG
TGATLIGLGAGGGGSIGGFAVNVGNGVGGLGGQGGQGAALIGLGAGGAGGAGGATVVGLGGNDGDGGDGGGLFSIGVGGD
GGNAGNGAMPANGGNGGNAGVIANGSFAPSFVGFGGNGGNGVNGGTGGTGGSGGILFGANGANGPS

Sequences:

>Translated_546_residues
MSFVTAAPEMLATAAQNVANIGTSLSAANATAAASTTSVLAAGADEVSQAIARLFSDYATHYQSLNAQAAAFHHSFVQTL
NAAGGAYSSAEAANASAQALEQNLLAVINAPAQALFGRPLIGNGANGTAASPNGGDGGILYGNGGNGFSQTTAGVAGGAG
GSAGLIGNGGNGGAGGAGAAGGAGGAGGWLLGNGGAGGPGGPTDVPAGTGGAGGAGGDAPLIGWGGNGGPGGFAAFGNGG
AGGNGGASGSLFGVGGAGGVGGSSEDVGGTGGAGGAGRGLFLGLGGDGGAGGTSNNNGGDGGAGGTAGGRLFSLGGDGGN
GGAGTAIGSNAGDGGAGGDSSALIGYAQGGSGGLGGFGESTGGDGGLGGAGAVLIGTGVGGFGGLGGGSNGTGGAGGAGG
TGATLIGLGAGGGGSIGGFAVNVGNGVGGLGGQGGQGAALIGLGAGGAGGAGGATVVGLGGNDGDGGDGGGLFSIGVGGD
GGNAGNGAMPANGGNGGNAGVIANGSFAPSFVGFGGNGGNGVNGGTGGTGGSGGILFGANGANGPS
>Mature_545_residues
SFVTAAPEMLATAAQNVANIGTSLSAANATAAASTTSVLAAGADEVSQAIARLFSDYATHYQSLNAQAAAFHHSFVQTLN
AAGGAYSSAEAANASAQALEQNLLAVINAPAQALFGRPLIGNGANGTAASPNGGDGGILYGNGGNGFSQTTAGVAGGAGG
SAGLIGNGGNGGAGGAGAAGGAGGAGGWLLGNGGAGGPGGPTDVPAGTGGAGGAGGDAPLIGWGGNGGPGGFAAFGNGGA
GGNGGASGSLFGVGGAGGVGGSSEDVGGTGGAGGAGRGLFLGLGGDGGAGGTSNNNGGDGGAGGTAGGRLFSLGGDGGNG
GAGTAIGSNAGDGGAGGDSSALIGYAQGGSGGLGGFGESTGGDGGLGGAGAVLIGTGVGGFGGLGGGSNGTGGAGGAGGT
GATLIGLGAGGGGSIGGFAVNVGNGVGGLGGQGGQGAALIGLGAGGAGGAGGATVVGLGGNDGDGGDGGGLFSIGVGGDG
GNAGNGAMPANGGNGGNAGVIANGSFAPSFVGFGGNGGNGVNGGTGGTGGSGGILFGANGANGPS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PE family. PGRS subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000084 [H]

Pfam domain/function: PF00934 PE [H]

EC number: NA

Molecular weight: Translated: 46591; Mature: 46460

Theoretical pI: Translated: 3.66; Mature: 3.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFVTAAPEMLATAAQNVANIGTSLSAANATAAASTTSVLAAGADEVSQAIARLFSDYAT
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
HYQSLNAQAAAFHHSFVQTLNAAGGAYSSAEAANASAQALEQNLLAVINAPAQALFGRPL
HHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHCCHHHHHHHHHHHEEECCCHHHHHCCCC
IGNGANGTAASPNGGDGGILYGNGGNGFSQTTAGVAGGAGGSAGLIGNGGNGGAGGAGAA
CCCCCCCCCCCCCCCCCCEEECCCCCCCCHHHCCCCCCCCCCCCEEECCCCCCCCCCCCC
GGAGGAGGWLLGNGGAGGPGGPTDVPAGTGGAGGAGGDAPLIGWGGNGGPGGFAAFGNGG
CCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCEEEECCCC
AGGNGGASGSLFGVGGAGGVGGSSEDVGGTGGAGGAGRGLFLGLGGDGGAGGTSNNNGGD
CCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCC
GGAGGTAGGRLFSLGGDGGNGGAGTAIGSNAGDGGAGGDSSALIGYAQGGSGGLGGFGES
CCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCC
TGGDGGLGGAGAVLIGTGVGGFGGLGGGSNGTGGAGGAGGTGATLIGLGAGGGGSIGGFA
CCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCEEE
VNVGNGVGGLGGQGGQGAALIGLGAGGAGGAGGATVVGLGGNDGDGGDGGGLFSIGVGGD
EECCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCEEEEEECCC
GGNAGNGAMPANGGNGGNAGVIANGSFAPSFVGFGGNGGNGVNGGTGGTGGSGGILFGAN
CCCCCCCCCCCCCCCCCCCCEEECCCCCCCEEECCCCCCCCCCCCCCCCCCCCCEEEECC
GANGPS
CCCCCC
>Mature Secondary Structure 
SFVTAAPEMLATAAQNVANIGTSLSAANATAAASTTSVLAAGADEVSQAIARLFSDYAT
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
HYQSLNAQAAAFHHSFVQTLNAAGGAYSSAEAANASAQALEQNLLAVINAPAQALFGRPL
HHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHCCHHHHHHHHHHHEEECCCHHHHHCCCC
IGNGANGTAASPNGGDGGILYGNGGNGFSQTTAGVAGGAGGSAGLIGNGGNGGAGGAGAA
CCCCCCCCCCCCCCCCCCEEECCCCCCCCHHHCCCCCCCCCCCCEEECCCCCCCCCCCCC
GGAGGAGGWLLGNGGAGGPGGPTDVPAGTGGAGGAGGDAPLIGWGGNGGPGGFAAFGNGG
CCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCEEEECCCC
AGGNGGASGSLFGVGGAGGVGGSSEDVGGTGGAGGAGRGLFLGLGGDGGAGGTSNNNGGD
CCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCC
GGAGGTAGGRLFSLGGDGGNGGAGTAIGSNAGDGGAGGDSSALIGYAQGGSGGLGGFGES
CCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCC
TGGDGGLGGAGAVLIGTGVGGFGGLGGGSNGTGGAGGAGGTGATLIGLGAGGGGSIGGFA
CCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCEEE
VNVGNGVGGLGGQGGQGAALIGLGAGGAGGAGGATVVGLGGNDGDGGDGGGLFSIGVGGD
EECCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCEEEEEECCC
GGNAGNGAMPANGGNGGNAGVIANGSFAPSFVGFGGNGGNGVNGGTGGTGGSGGILFGAN
CCCCCCCCCCCCCCCCCCCCEEECCCCCCCEEECCCCCCCCCCCCCCCCCCCCCEEEECC
GANGPS
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]