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The map label for this gene is acpS

Identifier: 121638406

GI number: 121638406

Start: 2803334

End: 2803726

Strand: Reverse

Name: acpS

Synonym: BCG_2544c

Alternate gene names: 121638406

Gene position: 2803726-2803334 (Counterclockwise)

Preceding gene: 121638407

Following gene: 121638405

Centisome position: 64.09

GC content: 68.7

Gene sequence:

>393_bases
ATGGGCATCGTCGGTGTGGGGATCGACCTGGTCTCCATTCCCGATTTCGCCGAGCAGGTCGACCAGCCCGGAACGGTGTT
CGCCGAGACCTTCACCCCGGGTGAGCGCCGGGACGCCTCGGACAAGAGTTCGTCGGCGGCCCGGCACCTGGCGGCCCGCT
GGGCCGCGAAGGAGGCGGTGATCAAGGCCTGGTCCGGATCGCGGTTCGCGCAGCGGCCGGTGTTGCCGGAGGACATCCAC
CGCGATATCGAGGTGGTCACCGATATGTGGGGCAGGCCGCGGGTCAGGCTGACCGGGGCCATCGCTGAGTATTTGGCCGA
CGTGACGATCCATGTGTCGCTGACCCACGAAGGGGATACCGCGGCCGCGGTCGCCATCCTGGAGGCCCCGTGA

Upstream 100 bases:

>100_bases
ACTGCCCGGCATCTCTTCGGTCCGTCCCCCGCAAGCGGGAGGTGCCCCCAACGCGGACCGCATCGTCGCCGGACTGGGCC
ATCGATTAACGTGGCCGCCC

Downstream 100 bases:

>100_bases
GCGCGAGCAGACGCAGAATCGCATCGAAATCCGGATTTTCATGCGACTCTGCGTCTGCTCGCGAGCTGGTTGAGCGCGTC
CGTGAGGTGTTGCCGTCGGT

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 130; Mature: 129

Protein sequence:

>130_residues
MGIVGVGIDLVSIPDFAEQVDQPGTVFAETFTPGERRDASDKSSSAARHLAARWAAKEAVIKAWSGSRFAQRPVLPEDIH
RDIEVVTDMWGRPRVRLTGAIAEYLADVTIHVSLTHEGDTAAAVAILEAP

Sequences:

>Translated_130_residues
MGIVGVGIDLVSIPDFAEQVDQPGTVFAETFTPGERRDASDKSSSAARHLAARWAAKEAVIKAWSGSRFAQRPVLPEDIH
RDIEVVTDMWGRPRVRLTGAIAEYLADVTIHVSLTHEGDTAAAVAILEAP
>Mature_129_residues
GIVGVGIDLVSIPDFAEQVDQPGTVFAETFTPGERRDASDKSSSAARHLAARWAAKEAVIKAWSGSRFAQRPVLPEDIHR
DIEVVTDMWGRPRVRLTGAIAEYLADVTIHVSLTHEGDTAAAVAILEAP

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_MYCBO (P0A4W9)

Other databases:

- EMBL:   BX248342
- RefSeq:   NP_856197.1
- ProteinModelPortal:   P0A4W9
- SMR:   P0A4W9
- EnsemblBacteria:   EBMYCT00000015334
- GeneID:   1090892
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb2552c
- GeneTree:   EBGT00050000016222
- HOGENOM:   HBG734479
- OMA:   IKAWSQA
- ProtClustDB:   PRK00070
- BioCyc:   MBOV233413:MB2552C-MONOMER
- BRENDA:   2.7.8.7
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 14003; Mature: 13872

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIVGVGIDLVSIPDFAEQVDQPGTVFAETFTPGERRDASDKSSSAARHLAARWAAKEAV
CCEEECCEEEEECCHHHHHCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
IKAWSGSRFAQRPVLPEDIHRDIEVVTDMWGRPRVRLTGAIAEYLADVTIHVSLTHEGDT
HHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHCCEEEEEEEECCCCC
AAAVAILEAP
EEEEEEEECC
>Mature Secondary Structure 
GIVGVGIDLVSIPDFAEQVDQPGTVFAETFTPGERRDASDKSSSAARHLAARWAAKEAV
CEEECCEEEEECCHHHHHCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
IKAWSGSRFAQRPVLPEDIHRDIEVVTDMWGRPRVRLTGAIAEYLADVTIHVSLTHEGDT
HHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHCCEEEEEEEECCCCC
AAAVAILEAP
EEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972