Click here to switch to the map view.

The map label for this gene is fadE19 [H]

Identifier: 121638382

GI number: 121638382

Start: 2777523

End: 2778707

Strand: Reverse

Name: fadE19 [H]

Synonym: BCG_2520c

Alternate gene names: 121638382

Gene position: 2778707-2777523 (Counterclockwise)

Preceding gene: 121638383

Following gene: 121638381

Centisome position: 63.52

GC content: 61.52

Gene sequence:

>1185_bases
ATGACCACAACGACTACAACGATTTCTGGGGGGATATTACCCAAGGAATACCAAGATCTTCGGGATACGGTGGCCGATTT
TGCGCGCACCGTGGTCGCGCCGGTATCGGCCAAACACGATGCGGAACACAGCTTCCCATACGAAATTGTCGCCAAGATGG
GAGAGATGGGCCTGTTCGGGCTGCCGTTTCCGGAGGAGTACGGCGGCATGGGCGGCGACTACTTCGCGCTGTCGCTGGTA
CTTGAGGAGCTGGGCAAGGTTGACCAATCGGTAGCGATCACGCTGGAGGCCGCGGTGGGCCTGGGTGCGATGCCGATCTA
CCGGTTCGGTACCGAGGAGCAGAAACAGAAGTGGTTGCCCGACTTGACGTCTGGCCGTGCGCTCGCCGGTTTTGGTCTCA
CCGAGCCGGGAGCGGGATCGGACGCGGGCAGCACCCGCACCACGGCGCGTCTCGAAGGTGACGAGTGGATCATCAACGGC
TCCAAGCAATTTATCACCAACTCGGGCACCGACATCACATCGCTGGTCACCGTCACTGCGGTTACCGGGACCACCGGAAC
CGCTGCGGATGCCAAGAAAGAGATTTCGACGATCATCGTGCCCAGCGGCACACCGGGATTCACCGTGGAACCGGTCTATA
ACAAGGTCGGCTGGAACGCCTCGGACACCCACCCACTGACATTTGCCGATGCGCGGGTCCCGAGGGAGAACCTGCTGGGA
GCCCGGGGGAGCGGCTATGCCAACTTCTTGTCCATCCTGGACGAGGGCCGGATTGCGATTGCAGCGCTGGCCACCGGCGC
GGCGCAGGGCTGTGTTGACGAGAGCGTCAAGTACGCCAACCAGCGTCAGTCGTTTGGCCAGCCGATCGGCGCTTATCAGG
CGATCGGCTTCAAGATCGCGCGGATGGAGGCACGCGCCCATGTTGCCCGCACAGCGTACTATGATGCCGCCGCAAAGATG
TTGGCGGGCAAGCCCTTCAAGAAGGAGGCGGCGATCGCGAAGATGATCTCCTCGGAGGCGGCGATGGACAACTCCCGCGA
TGCCACCCAGATACACGGCGGATACGGCTTTATGAACGAATATCCGGTGGCGCGTCATTACCGCGACAGCAAGGTGCTCG
AGATTGGTGAGGGCACCACGGAAGTGCAGCTGATGCTTATCGCGCGATCGTTGGGACTGCAGTGA

Upstream 100 bases:

>100_bases
TCGCTGGAGGCGCCGGTTTCGGGACGGGTACAGGTGTTGGTGTCCGTTGGCGATCAGGTGAAAGTCGAACAGGTACTGGC
GAGGATCAAGGACTAGGATC

Downstream 100 bases:

>100_bases
CAAAGCACGCCGGCGACCGTGAATCTGACGACGCCGTATCGGCGTGTCGCGTCGCAGGATCCACAGTCGGCAGAAGGATT
CTTCAACGAGGCTTGTGGTT

Product: putative acyl-CoA dehydrogenase fadE19

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 393

Protein sequence:

>394_residues
MTTTTTTISGGILPKEYQDLRDTVADFARTVVAPVSAKHDAEHSFPYEIVAKMGEMGLFGLPFPEEYGGMGGDYFALSLV
LEELGKVDQSVAITLEAAVGLGAMPIYRFGTEEQKQKWLPDLTSGRALAGFGLTEPGAGSDAGSTRTTARLEGDEWIING
SKQFITNSGTDITSLVTVTAVTGTTGTAADAKKEISTIIVPSGTPGFTVEPVYNKVGWNASDTHPLTFADARVPRENLLG
ARGSGYANFLSILDEGRIAIAALATGAAQGCVDESVKYANQRQSFGQPIGAYQAIGFKIARMEARAHVARTAYYDAAAKM
LAGKPFKKEAAIAKMISSEAAMDNSRDATQIHGGYGFMNEYPVARHYRDSKVLEIGEGTTEVQLMLIARSLGLQ

Sequences:

>Translated_394_residues
MTTTTTTISGGILPKEYQDLRDTVADFARTVVAPVSAKHDAEHSFPYEIVAKMGEMGLFGLPFPEEYGGMGGDYFALSLV
LEELGKVDQSVAITLEAAVGLGAMPIYRFGTEEQKQKWLPDLTSGRALAGFGLTEPGAGSDAGSTRTTARLEGDEWIING
SKQFITNSGTDITSLVTVTAVTGTTGTAADAKKEISTIIVPSGTPGFTVEPVYNKVGWNASDTHPLTFADARVPRENLLG
ARGSGYANFLSILDEGRIAIAALATGAAQGCVDESVKYANQRQSFGQPIGAYQAIGFKIARMEARAHVARTAYYDAAAKM
LAGKPFKKEAAIAKMISSEAAMDNSRDATQIHGGYGFMNEYPVARHYRDSKVLEIGEGTTEVQLMLIARSLGLQ
>Mature_393_residues
TTTTTTISGGILPKEYQDLRDTVADFARTVVAPVSAKHDAEHSFPYEIVAKMGEMGLFGLPFPEEYGGMGGDYFALSLVL
EELGKVDQSVAITLEAAVGLGAMPIYRFGTEEQKQKWLPDLTSGRALAGFGLTEPGAGSDAGSTRTTARLEGDEWIINGS
KQFITNSGTDITSLVTVTAVTGTTGTAADAKKEISTIIVPSGTPGFTVEPVYNKVGWNASDTHPLTFADARVPRENLLGA
RGSGYANFLSILDEGRIAIAALATGAAQGCVDESVKYANQRQSFGQPIGAYQAIGFKIARMEARAHVARTAYYDAAAKML
AGKPFKKEAAIAKMISSEAAMDNSRDATQIHGGYGFMNEYPVARHYRDSKVLEIGEGTTEVQLMLIARSLGLQ

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=379, Percent_Identity=42.4802110817942, Blast_Score=293, Evalue=2e-79,
Organism=Homo sapiens, GI4501859, Length=372, Percent_Identity=37.0967741935484, Blast_Score=243, Evalue=3e-64,
Organism=Homo sapiens, GI187960098, Length=375, Percent_Identity=35.4666666666667, Blast_Score=229, Evalue=3e-60,
Organism=Homo sapiens, GI4557231, Length=375, Percent_Identity=35.4666666666667, Blast_Score=229, Evalue=4e-60,
Organism=Homo sapiens, GI226958412, Length=381, Percent_Identity=33.8582677165354, Blast_Score=224, Evalue=2e-58,
Organism=Homo sapiens, GI7656849, Length=385, Percent_Identity=34.5454545454545, Blast_Score=219, Evalue=2e-57,
Organism=Homo sapiens, GI21361497, Length=364, Percent_Identity=38.1868131868132, Blast_Score=214, Evalue=1e-55,
Organism=Homo sapiens, GI76496475, Length=382, Percent_Identity=37.9581151832461, Blast_Score=212, Evalue=6e-55,
Organism=Homo sapiens, GI4557235, Length=382, Percent_Identity=37.9581151832461, Blast_Score=211, Evalue=8e-55,
Organism=Homo sapiens, GI226958414, Length=344, Percent_Identity=34.3023255813954, Blast_Score=210, Evalue=2e-54,
Organism=Homo sapiens, GI4501857, Length=381, Percent_Identity=32.8083989501312, Blast_Score=204, Evalue=1e-52,
Organism=Homo sapiens, GI4503943, Length=378, Percent_Identity=29.3650793650794, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI7669494, Length=349, Percent_Identity=30.0859598853868, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI38505218, Length=351, Percent_Identity=29.6296296296296, Blast_Score=121, Evalue=9e-28,
Organism=Homo sapiens, GI48976061, Length=289, Percent_Identity=28.719723183391, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI211971008, Length=289, Percent_Identity=28.719723183391, Blast_Score=100, Evalue=4e-21,
Organism=Escherichia coli, GI87081958, Length=353, Percent_Identity=31.1614730878187, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI1786223, Length=355, Percent_Identity=29.5774647887324, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI87081702, Length=342, Percent_Identity=29.2397660818713, Blast_Score=96, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17508101, Length=382, Percent_Identity=37.17277486911, Blast_Score=248, Evalue=3e-66,
Organism=Caenorhabditis elegans, GI17506239, Length=368, Percent_Identity=38.0434782608696, Blast_Score=240, Evalue=1e-63,
Organism=Caenorhabditis elegans, GI17534899, Length=379, Percent_Identity=38.2585751978892, Blast_Score=238, Evalue=4e-63,
Organism=Caenorhabditis elegans, GI17569725, Length=379, Percent_Identity=35.8839050131926, Blast_Score=228, Evalue=5e-60,
Organism=Caenorhabditis elegans, GI17570075, Length=394, Percent_Identity=34.2639593908629, Blast_Score=228, Evalue=6e-60,
Organism=Caenorhabditis elegans, GI17533517, Length=382, Percent_Identity=33.2460732984293, Blast_Score=216, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI17538396, Length=376, Percent_Identity=34.0425531914894, Blast_Score=215, Evalue=4e-56,
Organism=Caenorhabditis elegans, GI71985184, Length=355, Percent_Identity=34.9295774647887, Blast_Score=206, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI71990804, Length=284, Percent_Identity=40.1408450704225, Blast_Score=200, Evalue=9e-52,
Organism=Caenorhabditis elegans, GI17551932, Length=391, Percent_Identity=28.6445012787724, Blast_Score=179, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI17505929, Length=361, Percent_Identity=29.0858725761773, Blast_Score=168, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI71985192, Length=303, Percent_Identity=33.6633663366337, Blast_Score=167, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17534353, Length=381, Percent_Identity=29.1338582677165, Blast_Score=166, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI32563615, Length=236, Percent_Identity=40.2542372881356, Blast_Score=164, Evalue=9e-41,
Organism=Caenorhabditis elegans, GI71982178, Length=293, Percent_Identity=30.0341296928328, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17562446, Length=334, Percent_Identity=27.5449101796407, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17531909, Length=246, Percent_Identity=26.0162601626016, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI21356377, Length=379, Percent_Identity=37.7308707124011, Blast_Score=257, Evalue=8e-69,
Organism=Drosophila melanogaster, GI24646207, Length=380, Percent_Identity=37.8947368421053, Blast_Score=248, Evalue=7e-66,
Organism=Drosophila melanogaster, GI24666513, Length=372, Percent_Identity=39.247311827957, Blast_Score=246, Evalue=2e-65,
Organism=Drosophila melanogaster, GI24660351, Length=379, Percent_Identity=36.9393139841689, Blast_Score=241, Evalue=5e-64,
Organism=Drosophila melanogaster, GI21355753, Length=381, Percent_Identity=35.1706036745407, Blast_Score=218, Evalue=7e-57,
Organism=Drosophila melanogaster, GI281363737, Length=383, Percent_Identity=32.8981723237598, Blast_Score=202, Evalue=4e-52,
Organism=Drosophila melanogaster, GI19920834, Length=393, Percent_Identity=27.735368956743, Blast_Score=139, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 41917; Mature: 41786

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTTTTISGGILPKEYQDLRDTVADFARTVVAPVSAKHDAEHSFPYEIVAKMGEMGLFG
CCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCC
LPFPEEYGGMGGDYFALSLVLEELGKVDQSVAITLEAAVGLGAMPIYRFGTEEQKQKWLP
CCCCHHHCCCCCHHHHHHHHHHHHCCCCCEEEEEEEHHHCCCCCCEEECCCHHHHHHCCC
DLTSGRALAGFGLTEPGAGSDAGSTRTTARLEGDEWIINGSKQFITNSGTDITSLVTVTA
CCCCCCEEECCCCCCCCCCCCCCCCCEEEEECCCEEEECCCHHEEECCCCCHHHEEEEEE
VTGTTGTAADAKKEISTIIVPSGTPGFTVEPVYNKVGWNASDTHPLTFADARVPRENLLG
EECCCCCCHHHHHCCEEEEEECCCCCCEECHHHHHCCCCCCCCCCEEEECCCCCHHHHCC
ARGSGYANFLSILDEGRIAIAALATGAAQGCVDESVKYANQRQSFGQPIGAYQAIGFKIA
CCCCCHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHH
RMEARAHVARTAYYDAAAKMLAGKPFKKEAAIAKMISSEAAMDNSRDATQIHGGYGFMNE
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCC
YPVARHYRDSKVLEIGEGTTEVQLMLIARSLGLQ
CCHHHHCCCCCEEEECCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
TTTTTTISGGILPKEYQDLRDTVADFARTVVAPVSAKHDAEHSFPYEIVAKMGEMGLFG
CCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCC
LPFPEEYGGMGGDYFALSLVLEELGKVDQSVAITLEAAVGLGAMPIYRFGTEEQKQKWLP
CCCCHHHCCCCCHHHHHHHHHHHHCCCCCEEEEEEEHHHCCCCCCEEECCCHHHHHHCCC
DLTSGRALAGFGLTEPGAGSDAGSTRTTARLEGDEWIINGSKQFITNSGTDITSLVTVTA
CCCCCCEEECCCCCCCCCCCCCCCCCEEEEECCCEEEECCCHHEEECCCCCHHHEEEEEE
VTGTTGTAADAKKEISTIIVPSGTPGFTVEPVYNKVGWNASDTHPLTFADARVPRENLLG
EECCCCCCHHHHHCCEEEEEECCCCCCEECHHHHHCCCCCCCCCCEEEECCCCCHHHHCC
ARGSGYANFLSILDEGRIAIAALATGAAQGCVDESVKYANQRQSFGQPIGAYQAIGFKIA
CCCCCHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHH
RMEARAHVARTAYYDAAAKMLAGKPFKKEAAIAKMISSEAAMDNSRDATQIHGGYGFMNE
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCC
YPVARHYRDSKVLEIGEGTTEVQLMLIARSLGLQ
CCHHHHCCCCCEEEECCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]