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The map label for this gene is PE_PGRS43a [H]

Identifier: 121638372

GI number: 121638372

Start: 2768605

End: 2770032

Strand: Reverse

Name: PE_PGRS43a [H]

Synonym: BCG_2510c

Alternate gene names: 121638372

Gene position: 2770032-2768605 (Counterclockwise)

Preceding gene: 121638377

Following gene: 121638371

Centisome position: 63.32

GC content: 75.56

Gene sequence:

>1428_bases
ATGTCATATGTGATCGCGACGCCGGAGATGATGGCAACTGCGGCTTTTGATCTGGCGCGTATTGGTTCGCAGGTGAGCGC
GGCTAGTGCGGTCGCGGCGATGCCGACGACGGAAGTGGTGGCCGCCGGCGCCGACGAGGTGTCGGCGGGCATCGCGGCGT
TGTTCAGCGCGCACGCTCAGGAGTATCAGGCGCTAAGTGCGCAGGCCGCGGCGTTTCACGACCAGTTCGTGCACACGCTG
ACCGCGGCCGCGAGGTGGTACACGGCCACCGAGATCGCCAACGCCGCGGCGATGCGAGTCGTGCTCGGAGCCGTGAATGC
GCCCACCCAGACGCTACTGGGACGCCCGCTGATCGGCGATGGTGCGCACGGGACAGCGCCTGGGCAGCCCGGTGGGGCCG
GTGGATTGTTGTTCGGCAATGGCGGCAACGGCGCTGCCGGTGCCGTCGGGCAGGTGGGCGGCGCCGGCGGGGCGGCCGGG
TTATTTGGGATCGGCGGCGCCGGTGGCGCGGGCGGGGCGGGCGCACCCGGAGGTACCGGCGGGACGGGTGGATGGCTGGC
GGGTGGGGGCGGCGTCGGCGGTATGGGTGGGGCTGGTGGTGGCGCCGGCGGGGCGGGTGGCAACGCGGGCCTGTTCGGCA
ACGGCGGCGCCGGTGGTGCCGGTGGGGCTGGTGGTGGCGCCGGCGGCGCGGGCGGTAACGCGGGGTGGTTTGGTCATGGG
GGCGCTGGCGGCGTGGGTGGTGTAGGTGCGGCCGGGGCCAACGGTGCTACGCCCGGTCAGGATGGGGCGGCTGGTGTTGC
CGGGTCGGACGACGGTGCCGGCGGTGACGGTTTGGCAGGGTCGGACGGGGGCGATGGCGGTGCCGGTGGGGTGGGCGGCA
ACGGTGGTCGGGGAGGGTGGCTTCTCGGTAACGGCGGCGCCGGTGGCGTTGGCGGTGTCGGCGGGGCCGGTGGTGCCGGT
GCGGCCGGCGGTGCCGGCGGTGCCGGGGCTACCGGAATAAATGGGCCGGCCGGTATCTCGGCGGCCGGCGGTGACGGCGG
CGCCGGCGGCAATGGCGGTGCCGGCGGAAACGGCGGCGTGGGCGGCGCCGGGGGTGCTGGCGGGTCGGCTGGACTATTGG
GGTATGTCGGCCGGGCCGGAGACGGCGGGGCTGGCGGGGGTGGGGGGCTGGGTGGAGCGCCTGGTGACGGCGGTGCCGGC
GGCAACGGTGGCAGTTGGCTGGCCGCCGGTGACGGCGGGGCCGGCGGTCACGGTGGCGACCCGGGCCTGGGTGGGGCTGG
CGGAGCCGGGGGGGGCGTCGGGCGGCGCCGGTGCTCGCGCGGGGGCCAATGGTCTGGCGGCCGGCAACGACGGGCCGGTC
AGCGGCGGCAACGGCGGCAAAGGTGGCAATGGCGCCCACGCATCGGTCGCCGGCGGTCATGGCGGTAA

Upstream 100 bases:

>100_bases
TGTCGCGGCGGTAGTTGGGGTCGCTGGCTCAAGAGACCAAGGGGTCACTAGTCGCAGCGGGAGCGGCGCGGCGACGGTCG
GGCTATTGGGTAGGTGCGAG

Downstream 100 bases:

>100_bases
CGGCGGTGCCGGTGGCAACGGCGGGTTGGTCGGTGACGGTGGGGCCGGCGGTCATGGCGGTGACGGAGCCGCGGGTGCCG
GCTATGCCGATATGACGGCG

Product: PE-PGRS family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 475; Mature: 474

Protein sequence:

>475_residues
MSYVIATPEMMATAAFDLARIGSQVSAASAVAAMPTTEVVAAGADEVSAGIAALFSAHAQEYQALSAQAAAFHDQFVHTL
TAAARWYTATEIANAAAMRVVLGAVNAPTQTLLGRPLIGDGAHGTAPGQPGGAGGLLFGNGGNGAAGAVGQVGGAGGAAG
LFGIGGAGGAGGAGAPGGTGGTGGWLAGGGGVGGMGGAGGGAGGAGGNAGLFGNGGAGGAGGAGGGAGGAGGNAGWFGHG
GAGGVGGVGAAGANGATPGQDGAAGVAGSDDGAGGDGLAGSDGGDGGAGGVGGNGGRGGWLLGNGGAGGVGGVGGAGGAG
AAGGAGGAGATGINGPAGISAAGGDGGAGGNGGAGGNGGVGGAGGAGGSAGLLGYVGRAGDGGAGGGGGLGGAPGDGGAG
GNGGSWLAAGDGGAGGHGGDPGLGGAGGAGGGVGRRRCSRGGQWSGGRQRRAGQRRQRRQRWQWRPRIGRRRSWR

Sequences:

>Translated_475_residues
MSYVIATPEMMATAAFDLARIGSQVSAASAVAAMPTTEVVAAGADEVSAGIAALFSAHAQEYQALSAQAAAFHDQFVHTL
TAAARWYTATEIANAAAMRVVLGAVNAPTQTLLGRPLIGDGAHGTAPGQPGGAGGLLFGNGGNGAAGAVGQVGGAGGAAG
LFGIGGAGGAGGAGAPGGTGGTGGWLAGGGGVGGMGGAGGGAGGAGGNAGLFGNGGAGGAGGAGGGAGGAGGNAGWFGHG
GAGGVGGVGAAGANGATPGQDGAAGVAGSDDGAGGDGLAGSDGGDGGAGGVGGNGGRGGWLLGNGGAGGVGGVGGAGGAG
AAGGAGGAGATGINGPAGISAAGGDGGAGGNGGAGGNGGVGGAGGAGGSAGLLGYVGRAGDGGAGGGGGLGGAPGDGGAG
GNGGSWLAAGDGGAGGHGGDPGLGGAGGAGGGVGRRRCSRGGQWSGGRQRRAGQRRQRRQRWQWRPRIGRRRSWR
>Mature_474_residues
SYVIATPEMMATAAFDLARIGSQVSAASAVAAMPTTEVVAAGADEVSAGIAALFSAHAQEYQALSAQAAAFHDQFVHTLT
AAARWYTATEIANAAAMRVVLGAVNAPTQTLLGRPLIGDGAHGTAPGQPGGAGGLLFGNGGNGAAGAVGQVGGAGGAAGL
FGIGGAGGAGGAGAPGGTGGTGGWLAGGGGVGGMGGAGGGAGGAGGNAGLFGNGGAGGAGGAGGGAGGAGGNAGWFGHGG
AGGVGGVGAAGANGATPGQDGAAGVAGSDDGAGGDGLAGSDGGDGGAGGVGGNGGRGGWLLGNGGAGGVGGVGGAGGAGA
AGGAGGAGATGINGPAGISAAGGDGGAGGNGGAGGNGGVGGAGGAGGSAGLLGYVGRAGDGGAGGGGGLGGAPGDGGAGG
NGGSWLAAGDGGAGGHGGDPGLGGAGGAGGGVGRRRCSRGGQWSGGRQRRAGQRRQRRQRWQWRPRIGRRRSWR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PE family. PGRS subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000084 [H]

Pfam domain/function: PF00934 PE [H]

EC number: NA

Molecular weight: Translated: 41392; Mature: 41261

Theoretical pI: Translated: 10.08; Mature: 10.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYVIATPEMMATAAFDLARIGSQVSAASAVAAMPTTEVVAAGADEVSAGIAALFSAHAQ
CCEEECCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHH
EYQALSAQAAAFHDQFVHTLTAAARWYTATEIANAAAMRVVLGAVNAPTQTLLGRPLIGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCC
GAHGTAPGQPGGAGGLLFGNGGNGAAGAVGQVGGAGGAAGLFGIGGAGGAGGAGAPGGTG
CCCCCCCCCCCCCCEEEEECCCCCCCCCHHCCCCCCCCCHHEECCCCCCCCCCCCCCCCC
GTGGWLAGGGGVGGMGGAGGGAGGAGGNAGLFGNGGAGGAGGAGGGAGGAGGNAGWFGHG
CCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GAGGVGGVGAAGANGATPGQDGAAGVAGSDDGAGGDGLAGSDGGDGGAGGVGGNGGRGGW
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCE
LLGNGGAGGVGGVGGAGGAGAAGGAGGAGATGINGPAGISAAGGDGGAGGNGGAGGNGGV
EEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GGAGGAGGSAGLLGYVGRAGDGGAGGGGGLGGAPGDGGAGGNGGSWLAAGDGGAGGHGGD
CCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCC
PGLGGAGGAGGGVGRRRCSRGGQWSGGRQRRAGQRRQRRQRWQWRPRIGRRRSWR
CCCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
SYVIATPEMMATAAFDLARIGSQVSAASAVAAMPTTEVVAAGADEVSAGIAALFSAHAQ
CEEECCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHH
EYQALSAQAAAFHDQFVHTLTAAARWYTATEIANAAAMRVVLGAVNAPTQTLLGRPLIGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCC
GAHGTAPGQPGGAGGLLFGNGGNGAAGAVGQVGGAGGAAGLFGIGGAGGAGGAGAPGGTG
CCCCCCCCCCCCCCEEEEECCCCCCCCCHHCCCCCCCCCHHEECCCCCCCCCCCCCCCCC
GTGGWLAGGGGVGGMGGAGGGAGGAGGNAGLFGNGGAGGAGGAGGGAGGAGGNAGWFGHG
CCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GAGGVGGVGAAGANGATPGQDGAAGVAGSDDGAGGDGLAGSDGGDGGAGGVGGNGGRGGW
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCE
LLGNGGAGGVGGVGGAGGAGAAGGAGGAGATGINGPAGISAAGGDGGAGGNGGAGGNGGV
EEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GGAGGAGGSAGLLGYVGRAGDGGAGGGGGLGGAPGDGGAGGNGGSWLAAGDGGAGGHGGD
CCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCC
PGLGGAGGAGGGVGRRRCSRGGQWSGGRQRRAGQRRQRRQRWQWRPRIGRRRSWR
CCCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]