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The map label for this gene is yebQ [C]

Identifier: 121638342

GI number: 121638342

Start: 2726024

End: 2727550

Strand: Direct

Name: yebQ [C]

Synonym: BCG_2479

Alternate gene names: 121638342

Gene position: 2726024-2727550 (Clockwise)

Preceding gene: 121638341

Following gene: 121638346

Centisome position: 62.32

GC content: 63.0

Gene sequence:

>1527_bases
ATGACACCGCGCCAGCGGCTGACCGTGTTGGCAACGGGGCTGGGCATCTTCATGGTGTTCGTGGACGTCAACATCGTCAA
TGTCGCATTGCCCAGCATCCAAAAGGTGTTTCACACGGGCGAACAAGGTCTGCAGTGGGCGGTCGCCGGGTACAGCCTGG
GCATGGCGGCCGTGCTGATGAGTTGCGCCCTGCTGGGCGATCGCTACGGTCGCAGGCGCAGTTTTGTGTTCGGGGTCACG
CTCTTCGTCGTGAGCTCTATTGTCTGTGTGCTACCGGTCAGCCTGGCAGTTTTCACGGTCGCACGAGTGATCCAAGGTTT
AGGAGCGGCGTTCATCTCAGTGCTCTCGCTGGCCTTGCTAAGCCACTCCTTTCCCAATCCCCGAATGAAAGCACGGGCGA
TATCCAACTGGATGGCCATAGGCATGGTCGGTGCGGCATCTGCCCCCGCGCTGGGCGGGCTCATGGTCGACGGCCTCGGT
TGGCGCAGCGTGTTCCTGGTGAACGTTCCGCTCGGTGCCATCGTGTGGCTGCTGACGCTAGTCGGTGTCGACGAGTCACA
GGATCCCGAGCCCACTCAACTCGACTGGGTGGGACAGCTGACGCTTATCCCGGCCGTCGCCCTGATCGCATACACCATCA
TCGAGGCTCCCCGGTTCGACCGGCAGTCCGCCGGGTTCGTGGCGGCGTTGCTGTTAGCGGCTGGGGTACTGCTGTGGCTG
TTTGTTCGACACGAACACCGCGCCGCTTTCCCGTTGGTCGATCTCAAACTGTTCGCCGAGCCGTTGTACCGATCGGTGCT
GATCGTCTACTTCGTGGTGATGTCCTGCTTTTTCGGGACTCTGATGGTGATCACCCAGCACTTCCAAAATGTGCGCGACC
TATCGCCGCTGCACGCGGGTTTGATGATGTTGCCGGTCCCCGCGGGATTCGGGGTGGCGAGTCTGCTGGCGGGTAGGGCG
GTCAACAAATGGGGTCCTCAGCTCCCGGTGCTGACGTGCCTGGCGGCCATGTTCATCGGGTTGGCGATTTTCGCGATCTC
GATGGACCACGCGCATCCAGTGGCCCTTGTTGGCCTGACGATCTTTGGCGCGGGAGCCGGCGGCTGCGCCACACCGCTGT
TGCATCTTGGAATGACCAAGGTCGATGATGGCCGTGCCGGCATGGCCGCCGGGATGCTCAATCTGCAGCGGTCGCTGGGC
GGCATTTTCGGCGTCGCCTTCCTGGGCACCATTGTCGCGGCCTGGTTGGGTGCCGCGCTGCCGAACACCATGGCCGACGA
AATTCCCGATCCCATCGCTCGCGCGATCGTTGTCGACGTCATCGTGGACAGCGCGAATCCGCATGCCCACGCGGCATTTA
TCGGGCCAGGACACCGGATAACTGCGGCGCAGGAGGATGAGATCGTACTGGCCGCCGACGCGGTCTTCGTGAGCGGAATC
AAGCTCGCGTTGGGCGGCGCCGCCGTATTGCTGACCGGCGCGTTCGTCCTTGGTTGGACGCGCTTCCCCCGGACCCCCGC
CAGCTAA

Upstream 100 bases:

>100_bases
CCGGCTACGCATGAGTAAGAACCGCATTATGGGCAACCAACCGGAGAAGTCAGATGTGACTGCGGCACCCGACACCGTGG
AGGGCGATTCCCACACTGCA

Downstream 100 bases:

>100_bases
GTGGTCTCGCTCGGTGCGCCCCCACAGTCCCTGCGCCGAGATCGACGTTAGCGTCACGCCTTATGGTGATTTTCCGCTCT
GGCGTGGATCTCGGCGCATG

Product: putative integral membrane transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 508; Mature: 507

Protein sequence:

>508_residues
MTPRQRLTVLATGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVLMSCALLGDRYGRRRSFVFGVT
LFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALLSHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLG
WRSVFLVNVPLGAIVWLLTLVGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLWL
FVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHAGLMMLPVPAGFGVASLLAGRA
VNKWGPQLPVLTCLAAMFIGLAIFAISMDHAHPVALVGLTIFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLG
GIFGVAFLGTIVAAWLGAALPNTMADEIPDPIARAIVVDVIVDSANPHAHAAFIGPGHRITAAQEDEIVLAADAVFVSGI
KLALGGAAVLLTGAFVLGWTRFPRTPAS

Sequences:

>Translated_508_residues
MTPRQRLTVLATGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVLMSCALLGDRYGRRRSFVFGVT
LFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALLSHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLG
WRSVFLVNVPLGAIVWLLTLVGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLWL
FVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHAGLMMLPVPAGFGVASLLAGRA
VNKWGPQLPVLTCLAAMFIGLAIFAISMDHAHPVALVGLTIFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLG
GIFGVAFLGTIVAAWLGAALPNTMADEIPDPIARAIVVDVIVDSANPHAHAAFIGPGHRITAAQEDEIVLAADAVFVSGI
KLALGGAAVLLTGAFVLGWTRFPRTPAS
>Mature_507_residues
TPRQRLTVLATGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVLMSCALLGDRYGRRRSFVFGVTL
FVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALLSHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGW
RSVFLVNVPLGAIVWLLTLVGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLWLF
VRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHAGLMMLPVPAGFGVASLLAGRAV
NKWGPQLPVLTCLAAMFIGLAIFAISMDHAHPVALVGLTIFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGG
IFGVAFLGTIVAAWLGAALPNTMADEIPDPIARAIVVDVIVDSANPHAHAAFIGPGHRITAAQEDEIVLAADAVFVSGIK
LALGGAAVLLTGAFVLGWTRFPRTPAS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily

Homologues:

Organism=Escherichia coli, GI87081983, Length=416, Percent_Identity=29.8076923076923, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1788710, Length=410, Percent_Identity=24.8780487804878, Blast_Score=105, Evalue=7e-24,
Organism=Escherichia coli, GI1790195, Length=254, Percent_Identity=30.7086614173228, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI1789042, Length=415, Percent_Identity=24.3373493975904, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1790146, Length=173, Percent_Identity=29.4797687861272, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1788392, Length=313, Percent_Identity=29.073482428115, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y2459_MYCTU (O53186)

Other databases:

- EMBL:   BX842579
- EMBL:   AE000516
- PIR:   B70865
- RefSeq:   NP_216975.1
- RefSeq:   NP_337020.1
- ProteinModelPortal:   O53186
- EnsemblBacteria:   EBMYCT00000000706
- EnsemblBacteria:   EBMYCT00000071680
- GeneID:   888191
- GeneID:   925796
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT2534
- KEGG:   mtu:Rv2459
- TIGR:   MT2534
- TubercuList:   Rv2459
- GeneTree:   EBGT00050000014781
- HOGENOM:   HBG679341
- OMA:   HERRAPF
- ProtClustDB:   CLSK872052
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196

Pfam domain/function: PF07690 MFS_1; SSF103473 MFS_gen_substrate_transporter

EC number: NA

Molecular weight: Translated: 53480; Mature: 53349

Theoretical pI: Translated: 8.25; Mature: 8.25

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x178ce644)-; HASH(0x176f779c)-; HASH(0x16b2c5fc)-; HASH(0x17592534)-; HASH(0x17832fc4)-; HASH(0x174f0b54)-; HASH(0x17a859f8)-; HASH(0x17628a78)-; HASH(0x1757d7d8)-; HASH(0x179f5b54)-; HASH(0x1653f714)-; HASH(0x179edfe0)-; HASH(0x1732eaac)-; HASH(0x15e79bbc)-;

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPRQRLTVLATGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVLM
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCEEEHHHHHHHHHHHHH
SCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLTL
HCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCEEEEEECCHHHHHHHHHH
VGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLWL
HCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
FVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHAG
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHC
LMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIFAISMDHAHPVALVGLT
CEEEECCCCCCHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
IFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAAWLGAAL
HCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PNTMADEIPDPIARAIVVDVIVDSANPHAHAAFIGPGHRITAAQEDEIVLAADAVFVSGI
CCHHHHHCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEECCCCCCEEEEEHHHHHHHH
KLALGGAAVLLTGAFVLGWTRFPRTPAS
HHHHCHHHHHHHHHHHHHHHHCCCCCCH
>Mature Secondary Structure 
TPRQRLTVLATGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVLM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCEEEHHHHHHHHHHHHH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HHHHCHHHHHHHHHHHHHHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036