Click here to switch to the map view.

The map label for this gene is PE23

Identifier: 121638214

GI number: 121638214

Start: 2577826

End: 2578974

Strand: Direct

Name: PE23

Synonym: BCG_2349

Alternate gene names: 121638214

Gene position: 2577826-2578974 (Clockwise)

Preceding gene: 121638213

Following gene: 121638217

Centisome position: 58.93

GC content: 64.49

Gene sequence:

>1149_bases
ATGCAGTTCCTGAGCGTGATTCCAGAGCAGGTCGAGTCCGCGGCTCAAGATTTGGCGGGCATTCGCTCAGCGCTGAGCGC
GTCTTACGCGGCCGCAGCGGGACCCACAACAGCGGTGGTTTCCGCTGCCGAGGACGAGGTGTCGACCGCGATTGCGTCGA
TATTCGGCGCCTACGGTCGACAGTGCCAGGTTCTCAGCGCCCAGGCCTCCGCGTTTCATGACGAGTTCGTCAACCTGTTG
AAAACTGGCGCGACTGCATACCGCAACACCGAATTCGCCAACGCCCAAAGCAACGTGCTGAATGCAGTGAACGCACCGGC
CCGATCGCTGTTGGGGCACCCGAGCGCGGCTGAGAGCGTGCAGAACTCGGCCCCAACGCTAGGCGGTGGCCACAGCACCG
TGACCGCTGGGCTTGCCGCACAGGCCGGTCGTGCCGTCGCGACGGTCGAACAACAGGCTGCGGCTGCGGTTGCCCCGTTG
CCAAGCGCCGGCGCCGGACTGGCTCAGGTTGTCAACGGCGTCGTGACCGCCGGACAGGGTTCCGCCGCCAAACTTGCCAC
CGCGCTGCAGAGCGCCGCGCCCTGGCTGGCCAAGAGCGGCGGCGAGTTCATCGTGGCTGGGCAGAGCGCGCTGACCGGTG
TTGCTTTGCTGCAACCTGCCGTGGTCGGCGTTGTTCAGGCGGGCGGTACGTTCTTGACCGCCGGAACGAGCGCTGCTACC
GGACTGGGTCTGCTCACACTTGCTGGTGTTGAGTTCAGTCAAGGCGTTGGCAACCTTGCGCTGGCTTCAGGGACCGCCGC
GACCGGACTTGGTCTGCTGGGCAGTGCCGGTGTGCAACTGTTCAGTCCTGCCTTTTTACTGGCTGTGCCCACCGCGTTGG
GTGGAGTTGGCTCGCTCGCGATCGCAGTAGTTCAGCTTGTGCAAGGCGTCCAACACCTGTCGTTGGTTGTGCCGAACGTT
GTTGCCGGGATCGCTGCACTGCAGACCGCCGGTGCCCAGTTTGCCCAGGGTGTTAACCACACGATGCTGGCCGCTCAGCT
CGGTGCCCCTGGGATAGCTGTCTTACAGACCGCCGGTGGCCATTTTGCTCAAGGCATTGGCCACCTGACGACGGCTGGCA
ATGCCGCTGTCACGGTGCTGATCTCCTAG

Upstream 100 bases:

>100_bases
GGCGAACGCCAACTTGGCCCGAAAAGACCGGCATTTCACTACTATCAATGTGCCTCGATCGTCGTTGGATAACAACCGTA
GTGAGTCGAGAGGAACCAGT

Downstream 100 bases:

>100_bases
CCGGGCGGTCGAGCTTCATCCCGGAGCCGCTACGTTACGCCGAGATGCTGCACCCGGAGAATCGGTCCGATTGAGTTCTG
GGACCGATAAGTTCGGCTGG

Product: PE family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MQFLSVIPEQVESAAQDLAGIRSALSASYAAAAGPTTAVVSAAEDEVSTAIASIFGAYGRQCQVLSAQASAFHDEFVNLL
KTGATAYRNTEFANAQSNVLNAVNAPARSLLGHPSAAESVQNSAPTLGGGHSTVTAGLAAQAGRAVATVEQQAAAAVAPL
PSAGAGLAQVVNGVVTAGQGSAAKLATALQSAAPWLAKSGGEFIVAGQSALTGVALLQPAVVGVVQAGGTFLTAGTSAAT
GLGLLTLAGVEFSQGVGNLALASGTAATGLGLLGSAGVQLFSPAFLLAVPTALGGVGSLAIAVVQLVQGVQHLSLVVPNV
VAGIAALQTAGAQFAQGVNHTMLAAQLGAPGIAVLQTAGGHFAQGIGHLTTAGNAAVTVLIS

Sequences:

>Translated_382_residues
MQFLSVIPEQVESAAQDLAGIRSALSASYAAAAGPTTAVVSAAEDEVSTAIASIFGAYGRQCQVLSAQASAFHDEFVNLL
KTGATAYRNTEFANAQSNVLNAVNAPARSLLGHPSAAESVQNSAPTLGGGHSTVTAGLAAQAGRAVATVEQQAAAAVAPL
PSAGAGLAQVVNGVVTAGQGSAAKLATALQSAAPWLAKSGGEFIVAGQSALTGVALLQPAVVGVVQAGGTFLTAGTSAAT
GLGLLTLAGVEFSQGVGNLALASGTAATGLGLLGSAGVQLFSPAFLLAVPTALGGVGSLAIAVVQLVQGVQHLSLVVPNV
VAGIAALQTAGAQFAQGVNHTMLAAQLGAPGIAVLQTAGGHFAQGIGHLTTAGNAAVTVLIS
>Mature_382_residues
MQFLSVIPEQVESAAQDLAGIRSALSASYAAAAGPTTAVVSAAEDEVSTAIASIFGAYGRQCQVLSAQASAFHDEFVNLL
KTGATAYRNTEFANAQSNVLNAVNAPARSLLGHPSAAESVQNSAPTLGGGHSTVTAGLAAQAGRAVATVEQQAAAAVAPL
PSAGAGLAQVVNGVVTAGQGSAAKLATALQSAAPWLAKSGGEFIVAGQSALTGVALLQPAVVGVVQAGGTFLTAGTSAAT
GLGLLTLAGVEFSQGVGNLALASGTAATGLGLLGSAGVQLFSPAFLLAVPTALGGVGSLAIAVVQLVQGVQHLSLVVPNV
VAGIAALQTAGAQFAQGVNHTMLAAQLGAPGIAVLQTAGGHFAQGIGHLTTAGNAAVTVLIS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PE family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PE23_MYCBO (P0A685)

Other databases:

- EMBL:   BX248342
- RefSeq:   NP_856004.1
- ProteinModelPortal:   P0A685
- EnsemblBacteria:   EBMYCT00000014665
- GeneID:   1094342
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb2355
- GeneTree:   EBGT00050000014959
- HOGENOM:   HBG128011
- ProtClustDB:   CLSK799895
- BioCyc:   MBOV233413:MB2355-MONOMER
- InterPro:   IPR000084

Pfam domain/function: PF00934 PE

EC number: NA

Molecular weight: Translated: 36833; Mature: 36833

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS00147 ARGINASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x17716708)-; HASH(0x17900b98)-; HASH(0x171231c8)-; HASH(0x16fae2e0)-; HASH(0x1732eadc)-; HASH(0x17542d0c)-; HASH(0x17569114)-; HASH(0x1757d518)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFLSVIPEQVESAAQDLAGIRSALSASYAAAAGPTTAVVSAAEDEVSTAIASIFGAYGR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHEHHHHHHHHHHHHHHHHHCC
QCQVLSAQASAFHDEFVNLLKTGATAYRNTEFANAQSNVLNAVNAPARSLLGHPSAAESV
CEEEHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHCCCHHHHHCCCHHHHHH
QNSAPTLGGGHSTVTAGLAAQAGRAVATVEQQAAAAVAPLPSAGAGLAQVVNGVVTAGQG
HHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCC
SAAKLATALQSAAPWLAKSGGEFIVAGQSALTGVALLQPAVVGVVQAGGTFLTAGTSAAT
CHHHHHHHHHHHCCHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHH
GLGLLTLAGVEFSQGVGNLALASGTAATGLGLLGSAGVQLFSPAFLLAVPTALGGVGSLA
HHHHHHHHCCHHHCCCCCEEEECCCHHHHHHHHHHCCHHHHCCHHHHHHHHHHCCHHHHH
IAVVQLVQGVQHLSLVVPNVVAGIAALQTAGAQFAQGVNHTMLAAQLGAPGIAVLQTAGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEECCCC
HFAQGIGHLTTAGNAAVTVLIS
HHHHHHHHHCCCCCEEEEEEEH
>Mature Secondary Structure
MQFLSVIPEQVESAAQDLAGIRSALSASYAAAAGPTTAVVSAAEDEVSTAIASIFGAYGR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHEHHHHHHHHHHHHHHHHHCC
QCQVLSAQASAFHDEFVNLLKTGATAYRNTEFANAQSNVLNAVNAPARSLLGHPSAAESV
CEEEHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHCCCHHHHHCCCHHHHHH
QNSAPTLGGGHSTVTAGLAAQAGRAVATVEQQAAAAVAPLPSAGAGLAQVVNGVVTAGQG
HHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCC
SAAKLATALQSAAPWLAKSGGEFIVAGQSALTGVALLQPAVVGVVQAGGTFLTAGTSAAT
CHHHHHHHHHHHCCHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHH
GLGLLTLAGVEFSQGVGNLALASGTAATGLGLLGSAGVQLFSPAFLLAVPTALGGVGSLA
HHHHHHHHCCHHHCCCCCEEEECCCHHHHHHHHHHCCHHHHCCHHHHHHHHHHCCHHHHH
IAVVQLVQGVQHLSLVVPNVVAGIAALQTAGAQFAQGVNHTMLAAQLGAPGIAVLQTAGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEECCCC
HFAQGIGHLTTAGNAAVTVLIS
HHHHHHHHHCCCCCEEEEEEEH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972