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The map label for this gene is yfhR [C]

Identifier: 121638189

GI number: 121638189

Start: 2554946

End: 2555791

Strand: Reverse

Name: yfhR [C]

Synonym: BCG_2324c

Alternate gene names: 121638189

Gene position: 2555791-2554946 (Counterclockwise)

Preceding gene: 121638190

Following gene: 121638185

Centisome position: 58.42

GC content: 67.61

Gene sequence:

>846_bases
ATGTCGCTAAAGAGGTGTCGCGCGTTGCCGGTGGTCGCTATCGTCGCGCTGGTGGCATCGGGCGTGATTACGTTCATCTG
GTCGCAGCAGCGTCGGCTAATCTACTTCCCGTCTGCGGGTCCGGTGCCATCGGCTTCCTCCGTTTTGCCCGCCGGCCGCG
ATGTCGTGGTCGAAACACAAGATGGAATGCGCTTGGGTGGCTGGTACTTCCCGCATACTTCGGGCGGTAGTGGGCCCGCG
GTGCTGGTGTGCAATGGCAACGCCGGCGACCGGTCGATGCGTGCGGAGCTGGCTGTCGCGCTGCATGGCCTGGGCCTGTC
GGTGTTGCTGTTTGACTATCGCGGCTACGGCGGTAACCCGGGTCGGCCGTCTGAGCAGGGCCTGGCCGCCGACGCTCGGG
CCGCGCAGGAGTGGCTGTCCGGCCAGTCCGACGTCGACCCCGCGCGCATTGCCTATTTCGGCGAATCCCTCGGCGCGGCG
GTGGCGGTCGGGCTGGCCGTGCAACGGCCGCCGGCGGCACTCGTGCTGAGATCTCCGTTCACGTCGCTGGCCGAGGTCGG
CGCGGTGCACTACCCGTGGCTGCCGCTGCGCCGGTTGCTGCTGGACCACTACCCGTCGATCGAGCGCATCGCCTCTGTAC
ACGCGCCGGTGCTGGTCATCGCGGGCGGCAGCGACGACATCGTCCCCGCTACGCTTAGTGAGTGGCTGGTCGCAGCGGCC
GCCGAGCCTAAGCGATACGTGGTGGTTCCCGGTGTGGGTCACAACGACCCGGAACTACTCGATGGGCGGGTGATGCTCGA
TGCGATCCGGCGCTTCTTGACGGAGACGGCGGTGCTCGGACAGTGA

Upstream 100 bases:

>100_bases
CGTTGAATTTCGTGTCGATTTTCTGTTTGGAACGGTGGTTTCGGTAATCCACTGGTCGCGGGGACCCCGCTTTCGATGCG
TCGCACCGGTGCGGGGCTAG

Downstream 100 bases:

>100_bases
ACCGGGCATGACGACGCCCGCCGGTGTCCGGTGACTCGTGTGGCGTTGCTGACTACCGGTCGTGAGCTGAGCCAGGCCGC
ACCGCCGGCGCGGGCGCGCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MSLKRCRALPVVAIVALVASGVITFIWSQQRRLIYFPSAGPVPSASSVLPAGRDVVVETQDGMRLGGWYFPHTSGGSGPA
VLVCNGNAGDRSMRAELAVALHGLGLSVLLFDYRGYGGNPGRPSEQGLAADARAAQEWLSGQSDVDPARIAYFGESLGAA
VAVGLAVQRPPAALVLRSPFTSLAEVGAVHYPWLPLRRLLLDHYPSIERIASVHAPVLVIAGGSDDIVPATLSEWLVAAA
AEPKRYVVVPGVGHNDPELLDGRVMLDAIRRFLTETAVLGQ

Sequences:

>Translated_281_residues
MSLKRCRALPVVAIVALVASGVITFIWSQQRRLIYFPSAGPVPSASSVLPAGRDVVVETQDGMRLGGWYFPHTSGGSGPA
VLVCNGNAGDRSMRAELAVALHGLGLSVLLFDYRGYGGNPGRPSEQGLAADARAAQEWLSGQSDVDPARIAYFGESLGAA
VAVGLAVQRPPAALVLRSPFTSLAEVGAVHYPWLPLRRLLLDHYPSIERIASVHAPVLVIAGGSDDIVPATLSEWLVAAA
AEPKRYVVVPGVGHNDPELLDGRVMLDAIRRFLTETAVLGQ
>Mature_280_residues
SLKRCRALPVVAIVALVASGVITFIWSQQRRLIYFPSAGPVPSASSVLPAGRDVVVETQDGMRLGGWYFPHTSGGSGPAV
LVCNGNAGDRSMRAELAVALHGLGLSVLLFDYRGYGGNPGRPSEQGLAADARAAQEWLSGQSDVDPARIAYFGESLGAAV
AVGLAVQRPPAALVLRSPFTSLAEVGAVHYPWLPLRRLLLDHYPSIERIASVHAPVLVIAGGSDDIVPATLSEWLVAAAA
EPKRYVVVPGVGHNDPELLDGRVMLDAIRRFLTETAVLGQ

Specific function: Unknown

COG id: COG1073

COG function: function code R; Hydrolases of the alpha/beta superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To S.pombe bem46 and yeast YNL320w [H]

Homologues:

Organism=Homo sapiens, GI49355781, Length=266, Percent_Identity=29.6992481203008, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI194306564, Length=201, Percent_Identity=32.8358208955224, Blast_Score=101, Evalue=6e-22,
Organism=Homo sapiens, GI194306562, Length=197, Percent_Identity=32.994923857868, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI71051602, Length=225, Percent_Identity=28.4444444444444, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI71051600, Length=225, Percent_Identity=28.4444444444444, Blast_Score=98, Evalue=7e-21,
Organism=Homo sapiens, GI109689718, Length=185, Percent_Identity=34.5945945945946, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI24308097, Length=190, Percent_Identity=33.6842105263158, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI151301175, Length=212, Percent_Identity=30.6603773584906, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI32451492, Length=262, Percent_Identity=29.0076335877863, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI32528310, Length=262, Percent_Identity=29.0076335877863, Blast_Score=87, Evalue=1e-17,
Organism=Escherichia coli, GI226510965, Length=268, Percent_Identity=32.089552238806, Blast_Score=114, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI71988362, Length=198, Percent_Identity=34.3434343434343, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17566318, Length=309, Percent_Identity=24.2718446601942, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71997133, Length=190, Percent_Identity=26.8421052631579, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6324009, Length=278, Percent_Identity=29.136690647482, Blast_Score=90, Evalue=4e-19,
Organism=Drosophila melanogaster, GI17137566, Length=281, Percent_Identity=32.7402135231317, Blast_Score=107, Evalue=7e-24,
Organism=Drosophila melanogaster, GI281362521, Length=202, Percent_Identity=30.1980198019802, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI281362519, Length=202, Percent_Identity=30.1980198019802, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI28571878, Length=202, Percent_Identity=30.1980198019802, Blast_Score=93, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002925 [H]

Pfam domain/function: PF01738 DLH [H]

EC number: NA

Molecular weight: Translated: 29671; Mature: 29540

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLKRCRALPVVAIVALVASGVITFIWSQQRRLIYFPSAGPVPSASSVLPAGRDVVVETQ
CCHHHHHCCHHHHHHHHHHHHHHEEEECCCCEEEECCCCCCCCCCCCCCCCCCEEEEECC
DGMRLGGWYFPHTSGGSGPAVLVCNGNAGDRSMRAELAVALHGLGLSVLLFDYRGYGGNP
CCCEECCEECCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEEEECCCCCCC
GRPSEQGLAADARAAQEWLSGQSDVDPARIAYFGESLGAAVAVGLAVQRPPAALVLRSPF
CCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCH
TSLAEVGAVHYPWLPLRRLLLDHYPSIERIASVHAPVLVIAGGSDDIVPATLSEWLVAAA
HHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHC
AEPKRYVVVPGVGHNDPELLDGRVMLDAIRRFLTETAVLGQ
CCCCEEEEECCCCCCCHHHHCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SLKRCRALPVVAIVALVASGVITFIWSQQRRLIYFPSAGPVPSASSVLPAGRDVVVETQ
CHHHHHCCHHHHHHHHHHHHHHEEEECCCCEEEECCCCCCCCCCCCCCCCCCEEEEECC
DGMRLGGWYFPHTSGGSGPAVLVCNGNAGDRSMRAELAVALHGLGLSVLLFDYRGYGGNP
CCCEECCEECCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEEEECCCCCCC
GRPSEQGLAADARAAQEWLSGQSDVDPARIAYFGESLGAAVAVGLAVQRPPAALVLRSPF
CCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCH
TSLAEVGAVHYPWLPLRRLLLDHYPSIERIASVHAPVLVIAGGSDDIVPATLSEWLVAAA
HHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHC
AEPKRYVVVPGVGHNDPELLDGRVMLDAIRRFLTETAVLGQ
CCCCEEEEECCCCCCCHHHHCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]