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The map label for this gene is furA [H]

Identifier: 121637815

GI number: 121637815

Start: 2157179

End: 2157631

Strand: Reverse

Name: furA [H]

Synonym: BCG_1948c

Alternate gene names: 121637815

Gene position: 2157631-2157179 (Counterclockwise)

Preceding gene: 121637816

Following gene: 121637814

Centisome position: 49.32

GC content: 62.03

Gene sequence:

>453_bases
TTGTCTAGTGTGTCCTCTATACCGGACTACGCCGAACAGCTCCGGACGGCCGACCTGCGCGTGACCCGACCGCGCGTCGC
CGTCCTGGAAGCAGTGAATGCGCATCCACACGCCGACACGGAAACGATTTTCGGTGTCGTGCGTTTTGCGCTGCCCGACG
TATCCCGGCAAGCCGTGTACGACGTGCTGCATGCCCTGACCGCCGCGGGCTTGGTGCGAAAGATCCAACCCTCGGGCTCC
GTCGCGCGCTACGAGTCCAGGGTCGGCGACAACCACCATCACATCGTCTGCCGGTCTTGCGGGGTTATCGCCGATGTCGA
CTGTGCTGTTGGCGAGGCACCCTGTCTGACGGCCTCGGACCATAACGGCTTCCTGTTGGACGAGGCGGAGGTCATCTACT
GGGGTCTATGTCCTGATTGTTCGATATCCGACACTTCGCGATCACATCCGTGA

Upstream 100 bases:

>100_bases
CCCGCCATCCCACGATCCAGCGGCCCCGGGGCGATCGGGTCCTAGCAGACGCCTGTCACGCTAGCCAAAGTCTTGACTGA
TTCCAGAAAAGGGAGTCATA

Downstream 100 bases:

>100_bases
TCACAGCCCGATAACACCAACTCCTGGAAGGAATGCTGTGCCCGAGCAACACCCACCCATTACAGAAACCACCACCGGAG
CCGCTAGCAACGGCTGTCCC

Product: ferric uptake regulation protein furA

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 150; Mature: 149

Protein sequence:

>150_residues
MSSVSSIPDYAEQLRTADLRVTRPRVAVLEAVNAHPHADTETIFGVVRFALPDVSRQAVYDVLHALTAAGLVRKIQPSGS
VARYESRVGDNHHHIVCRSCGVIADVDCAVGEAPCLTASDHNGFLLDEAEVIYWGLCPDCSISDTSRSHP

Sequences:

>Translated_150_residues
MSSVSSIPDYAEQLRTADLRVTRPRVAVLEAVNAHPHADTETIFGVVRFALPDVSRQAVYDVLHALTAAGLVRKIQPSGS
VARYESRVGDNHHHIVCRSCGVIADVDCAVGEAPCLTASDHNGFLLDEAEVIYWGLCPDCSISDTSRSHP
>Mature_149_residues
SSVSSIPDYAEQLRTADLRVTRPRVAVLEAVNAHPHADTETIFGVVRFALPDVSRQAVYDVLHALTAAGLVRKIQPSGSV
ARYESRVGDNHHHIVCRSCGVIADVDCAVGEAPCLTASDHNGFLLDEAEVIYWGLCPDCSISDTSRSHP

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

None

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 16193; Mature: 16062

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
4.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSVSSIPDYAEQLRTADLRVTRPRVAVLEAVNAHPHADTETIFGVVRFALPDVSRQAVY
CCCCCCCHHHHHHHHHCCCEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHH
DVLHALTAAGLVRKIQPSGSVARYESRVGDNHHHIVCRSCGVIADVDCAVGEAPCLTASD
HHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCEEEEECCCCEEECCCCCCCCCEEEECC
HNGFLLDEAEVIYWGLCPDCSISDTSRSHP
CCCEEEECCCEEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure 
SSVSSIPDYAEQLRTADLRVTRPRVAVLEAVNAHPHADTETIFGVVRFALPDVSRQAVY
CCCCCCHHHHHHHHHCCCEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHH
DVLHALTAAGLVRKIQPSGSVARYESRVGDNHHHIVCRSCGVIADVDCAVGEAPCLTASD
HHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCEEEEECCCCEEECCCCCCCCCEEEECC
HNGFLLDEAEVIYWGLCPDCSISDTSRSHP
CCCEEEECCCEEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]