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The map label for this gene is ucpA [C]

Identifier: 121637786

GI number: 121637786

Start: 2133330

End: 2134163

Strand: Reverse

Name: ucpA [C]

Synonym: BCG_1919c

Alternate gene names: 121637786

Gene position: 2134163-2133330 (Counterclockwise)

Preceding gene: 121637787

Following gene: 121637785

Centisome position: 48.79

GC content: 64.27

Gene sequence:

>834_bases
ATGAAAGCGATATTCATCACCGGCGCCGGCAGTGGAATGGGCCGCGAGGGTGCAACGCTTTTCCACGCCAACGGCTGGCG
AGTAGGTGCGATAGACCGCAATGAGGATGGGCTGGCTGCCCTGCGCGTACAGCTTGGTGCCGAACGGCTGTGGGCCCGCG
CCGTCGACGTTACGGACAAGGCGGCCCTTGAGGGTGCGCTCGCTGATTTCTGCGCCGGCAATGTCGGCGGCGGTCTCGAC
ATGATGTGGAACAACGCCGGCATCGGCGAAGGCGGTTGGTTCGAGGACGTGCCGTACGAGGCCGCCGTGCGCGTCGTCGA
CGTGAACTTCAAGGCGGTGCTCACTGGCGCCTACGCCGCACTGCCTTACCTCAAGAAAGCACCGGGAAGTCTGATGTTCT
CGACGTCGTCGTCCTCGGGCACCTATGGCATGCCGCGTATCGCGGTCTACTCGGCGACCAAACACGCCGTCAAGGGGTTG
ACCGAGGCGTTGAGCGTTGAGTGGCAGCGTCATGGGGTTCGCGTCGCCGACGTGCTGCCCGGTCTGATCGACACCGCTAT
CCTCACCTCGACGCGCCAGCATTCCGACGAGGGCCCCTACACGATCTCCGCGGAGCAGATCCGCGCTGCCGCGCCCAAGA
AGGGCATGTTCCGGCTGATGCCCTCGTCCAGCGTCGCCGAGGCAGCCTGGCGGGCCTACCAGCACCCCACACGGTTGCAT
TGGTATGTGCCCCGAAGCATTCGCTGGATTGATCGGCTCAAGGGCGTCAGTCCGGAGTTCGTCCGACGTCACATTGCCAA
GTCCCTGGCCACGTTGGAGCCAAAACGGAAGTAA

Upstream 100 bases:

>100_bases
GCGTCAGCGCCGCAACATCCGAGACATGACCAAGACGTTGCAGCGCATCAAAGATCTGGTTGAAGCAGGCTGAGGGCGGT
TCGGCTATTCCGGATTCCGC

Downstream 100 bases:

>100_bases
TGTCCCGAGCACAATGCTCAGGCCCGAATGGAGGTGGCTGGTGTGCAATCGGTTGGTCACAGTGACCGGAGTTGCAATGG
TCGTCGCGGCTGGTCTCTCC

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MKAIFITGAGSGMGREGATLFHANGWRVGAIDRNEDGLAALRVQLGAERLWARAVDVTDKAALEGALADFCAGNVGGGLD
MMWNNAGIGEGGWFEDVPYEAAVRVVDVNFKAVLTGAYAALPYLKKAPGSLMFSTSSSSGTYGMPRIAVYSATKHAVKGL
TEALSVEWQRHGVRVADVLPGLIDTAILTSTRQHSDEGPYTISAEQIRAAAPKKGMFRLMPSSSVAEAAWRAYQHPTRLH
WYVPRSIRWIDRLKGVSPEFVRRHIAKSLATLEPKRK

Sequences:

>Translated_277_residues
MKAIFITGAGSGMGREGATLFHANGWRVGAIDRNEDGLAALRVQLGAERLWARAVDVTDKAALEGALADFCAGNVGGGLD
MMWNNAGIGEGGWFEDVPYEAAVRVVDVNFKAVLTGAYAALPYLKKAPGSLMFSTSSSSGTYGMPRIAVYSATKHAVKGL
TEALSVEWQRHGVRVADVLPGLIDTAILTSTRQHSDEGPYTISAEQIRAAAPKKGMFRLMPSSSVAEAAWRAYQHPTRLH
WYVPRSIRWIDRLKGVSPEFVRRHIAKSLATLEPKRK
>Mature_277_residues
MKAIFITGAGSGMGREGATLFHANGWRVGAIDRNEDGLAALRVQLGAERLWARAVDVTDKAALEGALADFCAGNVGGGLD
MMWNNAGIGEGGWFEDVPYEAAVRVVDVNFKAVLTGAYAALPYLKKAPGSLMFSTSSSSGTYGMPRIAVYSATKHAVKGL
TEALSVEWQRHGVRVADVLPGLIDTAILTSTRQHSDEGPYTISAEQIRAAAPKKGMFRLMPSSSVAEAAWRAYQHPTRLH
WYVPRSIRWIDRLKGVSPEFVRRHIAKSLATLEPKRK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI31542939, Length=217, Percent_Identity=29.4930875576037, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI20149619, Length=194, Percent_Identity=29.8969072164948, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI40807363, Length=263, Percent_Identity=29.6577946768061, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI7705925, Length=200, Percent_Identity=31.5, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI4503817, Length=190, Percent_Identity=27.8947368421053, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI32455239, Length=190, Percent_Identity=31.5789473684211, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI5031765, Length=190, Percent_Identity=31.5789473684211, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI40548397, Length=195, Percent_Identity=31.7948717948718, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI214010158, Length=195, Percent_Identity=31.7948717948718, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI214010156, Length=195, Percent_Identity=31.7948717948718, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI22758144, Length=195, Percent_Identity=31.7948717948718, Blast_Score=69, Evalue=7e-12,
Organism=Escherichia coli, GI87082100, Length=212, Percent_Identity=29.7169811320755, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787820, Length=235, Percent_Identity=26.3829787234043, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1788459, Length=184, Percent_Identity=30.4347826086957, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1790717, Length=191, Percent_Identity=28.2722513089005, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787335, Length=200, Percent_Identity=29.5, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17562990, Length=198, Percent_Identity=30.8080808080808, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17560150, Length=198, Percent_Identity=29.2929292929293, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71994600, Length=238, Percent_Identity=30.2521008403361, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI71994604, Length=239, Percent_Identity=27.6150627615063, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17544670, Length=201, Percent_Identity=29.8507462686567, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17559104, Length=200, Percent_Identity=28.5, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193204405, Length=193, Percent_Identity=30.0518134715026, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17563726, Length=198, Percent_Identity=28.2828282828283, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI193203117, Length=191, Percent_Identity=29.8429319371728, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI193203115, Length=191, Percent_Identity=29.8429319371728, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17560220, Length=201, Percent_Identity=29.3532338308458, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI72000259, Length=198, Percent_Identity=26.7676767676768, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17564282, Length=192, Percent_Identity=27.6041666666667, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17508895, Length=193, Percent_Identity=28.4974093264249, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17562908, Length=194, Percent_Identity=26.8041237113402, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17562906, Length=200, Percent_Identity=28.5, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322226, Length=225, Percent_Identity=26.2222222222222, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322067, Length=187, Percent_Identity=27.807486631016, Blast_Score=66, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24639444, Length=189, Percent_Identity=32.2751322751323, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21357041, Length=190, Percent_Identity=31.0526315789474, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28571526, Length=203, Percent_Identity=31.5270935960591, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI23397609, Length=189, Percent_Identity=31.2169312169312, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21358495, Length=192, Percent_Identity=28.6458333333333, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24644339, Length=193, Percent_Identity=29.5336787564767, Blast_Score=68, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 30011; Mature: 30011

Theoretical pI: Translated: 10.08; Mature: 10.08

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAIFITGAGSGMGREGATLFHANGWRVGAIDRNEDGLAALRVQLGAERLWARAVDVTDK
CEEEEEEECCCCCCCCCCEEEECCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHH
AALEGALADFCAGNVGGGLDMMWNNAGIGEGGWFEDVPYEAAVRVVDVNFKAVLTGAYAA
HHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCHHHEEEEEECCHHHHHHHHHHH
LPYLKKAPGSLMFSTSSSSGTYGMPRIAVYSATKHAVKGLTEALSVEWQRHGVRVADVLP
HHHHHCCCCCEEEEECCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCEEHHHHHH
GLIDTAILTSTRQHSDEGPYTISAEQIRAAAPKKGMFRLMPSSSVAEAAWRAYQHPTRLH
HHHHHHHHHHHHCCCCCCCEEEEHHHHHHCCCCCCEEEECCCCHHHHHHHHHHCCCCEEE
WYVPRSIRWIDRLKGVSPEFVRRHIAKSLATLEPKRK
EECCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKAIFITGAGSGMGREGATLFHANGWRVGAIDRNEDGLAALRVQLGAERLWARAVDVTDK
CEEEEEEECCCCCCCCCCEEEECCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHH
AALEGALADFCAGNVGGGLDMMWNNAGIGEGGWFEDVPYEAAVRVVDVNFKAVLTGAYAA
HHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCHHHEEEEEECCHHHHHHHHHHH
LPYLKKAPGSLMFSTSSSSGTYGMPRIAVYSATKHAVKGLTEALSVEWQRHGVRVADVLP
HHHHHCCCCCEEEEECCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCEEHHHHHH
GLIDTAILTSTRQHSDEGPYTISAEQIRAAAPKKGMFRLMPSSSVAEAAWRAYQHPTRLH
HHHHHHHHHHHHCCCCCCCEEEEHHHHHHCCCCCCEEEECCCCHHHHHHHHHHCCCCEEE
WYVPRSIRWIDRLKGVSPEFVRRHIAKSLATLEPKRK
EECCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11418146 [H]