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The map label for this gene is ytfL [C]

Identifier: 121637744

GI number: 121637744

Start: 2090635

End: 2091684

Strand: Reverse

Name: ytfL [C]

Synonym: BCG_1877c

Alternate gene names: 121637744

Gene position: 2091684-2090635 (Counterclockwise)

Preceding gene: 121637745

Following gene: 121637743

Centisome position: 47.82

GC content: 64.95

Gene sequence:

>1050_bases
ATGGATGTGCTGTCCGCGGTGTTGCTGGCGCTTTTGCTGATCGGCGCCAACGCGTTCTTCGTGGGCGCGGAATTCGCGTT
GATCTCGGCGCGTCGTGACCGCCTCGAAGCGCTGGCCGAGCAGGGCAAGGCCACTGCCGTCACCGTGATCCGGGCGGGCG
AACAGCTCCCGGCGATGCTGACCGGCGCACAGCTGGGGGTTACGGTGTCCTCGATCCTGCTTGGCCGGGTCGGCGAACCG
GCAGTCGTCAAGCTGCTACAGCTGTCGTTCGGGCTGAGCGGTGTACCGCCGGCGCTGCTGCACACCTTGTCGTTGGCGGT
GGCGTTGGCGATCGTGGTGGCGCTGCATGTCCTGCTCGGTGAGATGGTGCCGAAGAACATCGCTTTGGCTGGTCCGGAGC
GAACAGCGATGTTGCTGGTCCCGCCGTACCTGGTCTACGTGCGCCTCGCCCGGCCGTTCATCGCGTTCTACAACAACTGC
GCCAACGCGATACTGCGGCTGGTTGGGGTGCAGCCGAAGGATGAACTCGACATCGCCGTCTCCACTGCGGAACTGTCCGA
GATGATCGCCGAATCGCTATCCGAAGGCCTGCTGGATCACGAGGAGCACACGCGGCTAACCCGAGCCCTTCGGATTCGAA
CTCGCCTGGTTGCCGATGTCGCGGTGCCGCTGGTCAACATTCGGGCAGTGCAGGTGTCGGCGGTAGGGTCCGGGCCCACC
ATCGGCGGGGTCGAACAGGCCTTGGCGCAAACCGGCTACTCCCGCTTTCCGGTGGTGGATCGCGGTGGAAGGTTCATCGG
ATATCTGCACATCAAGGACGTGCTGACCCTCGGTGACAATCCGCAAACCGTGATCGATCTGGCCGTTGTGCGCCCGCTGC
CGCGGGTTCCCCAATCGTTGCCGCTGGCCGACGCCCTGTCGCGGATGCGGCGCATCAACAGCCATCTGGCCTTGGTAACC
GCCGACAACGGTTCTGTCGTGGGGATGGTGGCGCTGGAGGACGTGGTGGAGGACCTGGTTGGCACCATGCGCGACGGGAC
GCATCGTTGA

Upstream 100 bases:

>100_bases
GGTTAGCCACCGTGATCCAGATGGACGGGCGCCGGATCGACTCGTTGGAGTTGATCAAAATGGGCGGCCATGCCGACCCC
GGGTCGGGGCGGGGCCGCTG

Downstream 100 bases:

>100_bases
CTGACGCAGGGATCGGTGTCTGACGGGACACCGAGCGTAATCGGGGGCTGCTGCCGCTGACAATCGTTTCGGATCAGTTG
GCCCGAACGCCGGACGTGGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MDVLSAVLLALLLIGANAFFVGAEFALISARRDRLEALAEQGKATAVTVIRAGEQLPAMLTGAQLGVTVSSILLGRVGEP
AVVKLLQLSFGLSGVPPALLHTLSLAVALAIVVALHVLLGEMVPKNIALAGPERTAMLLVPPYLVYVRLARPFIAFYNNC
ANAILRLVGVQPKDELDIAVSTAELSEMIAESLSEGLLDHEEHTRLTRALRIRTRLVADVAVPLVNIRAVQVSAVGSGPT
IGGVEQALAQTGYSRFPVVDRGGRFIGYLHIKDVLTLGDNPQTVIDLAVVRPLPRVPQSLPLADALSRMRRINSHLALVT
ADNGSVVGMVALEDVVEDLVGTMRDGTHR

Sequences:

>Translated_349_residues
MDVLSAVLLALLLIGANAFFVGAEFALISARRDRLEALAEQGKATAVTVIRAGEQLPAMLTGAQLGVTVSSILLGRVGEP
AVVKLLQLSFGLSGVPPALLHTLSLAVALAIVVALHVLLGEMVPKNIALAGPERTAMLLVPPYLVYVRLARPFIAFYNNC
ANAILRLVGVQPKDELDIAVSTAELSEMIAESLSEGLLDHEEHTRLTRALRIRTRLVADVAVPLVNIRAVQVSAVGSGPT
IGGVEQALAQTGYSRFPVVDRGGRFIGYLHIKDVLTLGDNPQTVIDLAVVRPLPRVPQSLPLADALSRMRRINSHLALVT
ADNGSVVGMVALEDVVEDLVGTMRDGTHR
>Mature_349_residues
MDVLSAVLLALLLIGANAFFVGAEFALISARRDRLEALAEQGKATAVTVIRAGEQLPAMLTGAQLGVTVSSILLGRVGEP
AVVKLLQLSFGLSGVPPALLHTLSLAVALAIVVALHVLLGEMVPKNIALAGPERTAMLLVPPYLVYVRLARPFIAFYNNC
ANAILRLVGVQPKDELDIAVSTAELSEMIAESLSEGLLDHEEHTRLTRALRIRTRLVADVAVPLVNIRAVQVSAVGSGPT
IGGVEQALAQTGYSRFPVVDRGGRFIGYLHIKDVLTLGDNPQTVIDLAVVRPLPRVPQSLPLADALSRMRRINSHLALVT
ADNGSVVGMVALEDVVEDLVGTMRDGTHR

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=336, Percent_Identity=30.952380952381, Blast_Score=186, Evalue=3e-47,
Organism=Escherichia coli, GI1790664, Length=344, Percent_Identity=24.4186046511628, Blast_Score=111, Evalue=9e-26,
Organism=Escherichia coli, GI145693175, Length=331, Percent_Identity=22.0543806646526, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI87082033, Length=190, Percent_Identity=27.8947368421053, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000644
- InterPro:   IPR002550 [H]

Pfam domain/function: PF00571 CBS; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 37040; Mature: 37040

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVLSAVLLALLLIGANAFFVGAEFALISARRDRLEALAEQGKATAVTVIRAGEQLPAML
CCHHHHHHHHHHHHCCCHHEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHH
TGAQLGVTVSSILLGRVGEPAVVKLLQLSFGLSGVPPALLHTLSLAVALAIVVALHVLLG
CCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EMVPKNIALAGPERTAMLLVPPYLVYVRLARPFIAFYNNCANAILRLVGVQPKDELDIAV
HHCCCCEEECCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
STAELSEMIAESLSEGLLDHEEHTRLTRALRIRTRLVADVAVPLVNIRAVQVSAVGSGPT
EHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCC
IGGVEQALAQTGYSRFPVVDRGGRFIGYLHIKDVLTLGDNPQTVIDLAVVRPLPRVPQSL
CCHHHHHHHHCCCCCCCEEECCCCEEEEEEEEHHHCCCCCCHHHHHHHHHCCCCCCCCCC
PLADALSRMRRINSHLALVTADNGSVVGMVALEDVVEDLVGTMRDGTHR
CHHHHHHHHHHHCCCEEEEEECCCCEEEHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MDVLSAVLLALLLIGANAFFVGAEFALISARRDRLEALAEQGKATAVTVIRAGEQLPAML
CCHHHHHHHHHHHHCCCHHEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHH
TGAQLGVTVSSILLGRVGEPAVVKLLQLSFGLSGVPPALLHTLSLAVALAIVVALHVLLG
CCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EMVPKNIALAGPERTAMLLVPPYLVYVRLARPFIAFYNNCANAILRLVGVQPKDELDIAV
HHCCCCEEECCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
STAELSEMIAESLSEGLLDHEEHTRLTRALRIRTRLVADVAVPLVNIRAVQVSAVGSGPT
EHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCC
IGGVEQALAQTGYSRFPVVDRGGRFIGYLHIKDVLTLGDNPQTVIDLAVVRPLPRVPQSL
CCHHHHHHHHCCCCCCCEEECCCCEEEEEEEEHHHCCCCCCHHHHHHHHHCCCCCCCCCC
PLADALSRMRRINSHLALVTADNGSVVGMVALEDVVEDLVGTMRDGTHR
CHHHHHHHHHHHCCCEEEEEECCCCEEEHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]