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The map label for this gene is yfmR [H]

Identifier: 121637575

GI number: 121637575

Start: 1898841

End: 1900616

Strand: Reverse

Name: yfmR [H]

Synonym: BCG_1706c

Alternate gene names: 121637575

Gene position: 1900616-1898841 (Counterclockwise)

Preceding gene: 121637579

Following gene: 121637574

Centisome position: 43.45

GC content: 67.68

Gene sequence:

>1776_bases
ATGGCGCACCTACTCGGAGCCGAGGCCGTGCACCTGGCCTATCCGACTCAGGTGGTGTTCGAGGCAGTCACGCTCGGGGT
CAACGACGGGGCGCGCATCGGCATCGTCGGGCGAAACGGCGACGGCAAATCCAGTCTGCTGGGCCTGCTCACCGGTCAAC
TGCGGCCGGACTCCGGTCGGGTCACCCGGCGTAGCGGATTGCGGGTGAACGCGCTCAGCCAAACAGACACCCTCGACCCC
AACCGCACCGTCGGCTGGACGCTCATCGGTGACCAACCCGAACACCAATGGGCGGGCAACCCGCGTATCCGGGACGTGGT
CGCCGGCCTGGTATCCGACATCGCCTGGGACACCCCGGTCAGCACCCTCAGCGGTGGCCAGCGCCGACGGGTGCAACTGG
CCAGCCTGCTGGTCGGCGAATGGGACGTGATCGCTCTCGACGAGCCCACCAACCACCTCGACATCCAAGGCATCACCTGG
CTCGCCGACCACCTACGGCGGCGCTGGGCCCGCAATACCGGCGGCCTACTCGTGGTCACCCACGACCGCTGGTTCCTCGA
CGAGGTCGCCACCACAACATGGGAAGTGCACGACGGAATCGTCGAACCTTTCGAAGGCGGCTACGCGGCGTACGTGCTGC
AGCGCGTCGAGCGGGACCGGCTGACCGCCGCGGCCGAAGCCAAGCGGCAGAACCTGCTGCGCAAGGAGCTGGCTTGGTTG
CGCCGCGGCGCACCGGCGCGGACCTGCAAGCCCAAGTTCCGGATCGAGGCCGCCAACCAACTGATCGCAGACGTGCCGCC
ACCGCGCAACACCGTGGAGCTGGCCAAGCTGGCGGCCGCTCGGCTCGGAAAGGACGTCGTCGACCTGCTCGGCGTGTCGG
TCTCGTACCAGCCTTCTGGGGGCCGCCCGGTGTTGCGCGACATCGAATGGCGGATCGGCCCGGGTGAACGTATCGGCATC
GTCGGGGCTAACGGCGCCGGCAAGTCGACCCTGCTGGGCTTGATCGCCGGCACCGTCCAGCCCGGTGTCGGACGTGTCAA
GCGCGGCAAGACCGTCCGGCTGGCAGTGCTCGATCAGCACGGGGACGATCTGGCACCGTTTGCCGACGACCGGATCGCCG
ATGTGCTAGGCAGGCTGCGTGGCGGCTATCAGGTCGAAGGCCGCGAGGTTACCCCGACCCAGCTGCTAGAGCGTCTCGGG
TTCCGCCGGGACCAGCTGTCCGCGCGAGTCGACGACCTCTCCGGTGGTCAGCGTCGGCGGTTGCAGCTCATGCTGACGCT
GTTGTCCGAGCCGAACGTGCTGCTCCTCGACGAGCCCACCAACGACGTGGACACCGAGATGCTGACGGCGACCGAAGACC
TGCTTGACTCGTGGGCGGGTACGTTGATCGTCGTCTCACACGACCGGTATCTGCTCGAGCGGGTCACTGACCAGCAGTAC
GCGATTCTCGATGACCGGTTGCGGCACCTGCCCGGCGGCATCGACGAATACCTGCAGCTGGCTGCCCGCGTTAGCGCCCC
AGCACCGGCCGAGCGGCCAGCGCCGCCGGCGATGTCGGGCGCACAGCGACGTGCCACCGAAAAAGAGTTGGCCGCAGTCG
ACCGTCAACTCGCCCGCCTGGCCGACCGGGTGGCCGCCAAACATACCGAACTGGCCGAGCATGACCAGTCCGACCACGTC
GGCATCACCCGGCTGACCCAGCAACTACGTGTCCTGCAAGACCACGTCGCGGCGATGGAGAATCGCTGGCTGGAGCTTTC
GGAGATGCTCGAATGA

Upstream 100 bases:

>100_bases
GGCCCATCCCAGCCCGCATCGTCGCCACGCTAGAGCTCGACCGCGCGGCTCCTCAGCGGCCCATCCCAGCCCGCATCGTC
GCCACGCTAGGGTCGGCCCC

Downstream 100 bases:

>100_bases
GGACGTATCGGACGGTGCGCTACCCGCTTGGCGAAGCGCTGCTGGCGCTGTATCGATGGCGCGGTCCGCTGATCAACGCC
GGAGTCGGTGGGCATGGCTA

Product: macrolide ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 591; Mature: 590

Protein sequence:

>591_residues
MAHLLGAEAVHLAYPTQVVFEAVTLGVNDGARIGIVGRNGDGKSSLLGLLTGQLRPDSGRVTRRSGLRVNALSQTDTLDP
NRTVGWTLIGDQPEHQWAGNPRIRDVVAGLVSDIAWDTPVSTLSGGQRRRVQLASLLVGEWDVIALDEPTNHLDIQGITW
LADHLRRRWARNTGGLLVVTHDRWFLDEVATTTWEVHDGIVEPFEGGYAAYVLQRVERDRLTAAAEAKRQNLLRKELAWL
RRGAPARTCKPKFRIEAANQLIADVPPPRNTVELAKLAAARLGKDVVDLLGVSVSYQPSGGRPVLRDIEWRIGPGERIGI
VGANGAGKSTLLGLIAGTVQPGVGRVKRGKTVRLAVLDQHGDDLAPFADDRIADVLGRLRGGYQVEGREVTPTQLLERLG
FRRDQLSARVDDLSGGQRRRLQLMLTLLSEPNVLLLDEPTNDVDTEMLTATEDLLDSWAGTLIVVSHDRYLLERVTDQQY
AILDDRLRHLPGGIDEYLQLAARVSAPAPAERPAPPAMSGAQRRATEKELAAVDRQLARLADRVAAKHTELAEHDQSDHV
GITRLTQQLRVLQDHVAAMENRWLELSEMLE

Sequences:

>Translated_591_residues
MAHLLGAEAVHLAYPTQVVFEAVTLGVNDGARIGIVGRNGDGKSSLLGLLTGQLRPDSGRVTRRSGLRVNALSQTDTLDP
NRTVGWTLIGDQPEHQWAGNPRIRDVVAGLVSDIAWDTPVSTLSGGQRRRVQLASLLVGEWDVIALDEPTNHLDIQGITW
LADHLRRRWARNTGGLLVVTHDRWFLDEVATTTWEVHDGIVEPFEGGYAAYVLQRVERDRLTAAAEAKRQNLLRKELAWL
RRGAPARTCKPKFRIEAANQLIADVPPPRNTVELAKLAAARLGKDVVDLLGVSVSYQPSGGRPVLRDIEWRIGPGERIGI
VGANGAGKSTLLGLIAGTVQPGVGRVKRGKTVRLAVLDQHGDDLAPFADDRIADVLGRLRGGYQVEGREVTPTQLLERLG
FRRDQLSARVDDLSGGQRRRLQLMLTLLSEPNVLLLDEPTNDVDTEMLTATEDLLDSWAGTLIVVSHDRYLLERVTDQQY
AILDDRLRHLPGGIDEYLQLAARVSAPAPAERPAPPAMSGAQRRATEKELAAVDRQLARLADRVAAKHTELAEHDQSDHV
GITRLTQQLRVLQDHVAAMENRWLELSEMLE
>Mature_590_residues
AHLLGAEAVHLAYPTQVVFEAVTLGVNDGARIGIVGRNGDGKSSLLGLLTGQLRPDSGRVTRRSGLRVNALSQTDTLDPN
RTVGWTLIGDQPEHQWAGNPRIRDVVAGLVSDIAWDTPVSTLSGGQRRRVQLASLLVGEWDVIALDEPTNHLDIQGITWL
ADHLRRRWARNTGGLLVVTHDRWFLDEVATTTWEVHDGIVEPFEGGYAAYVLQRVERDRLTAAAEAKRQNLLRKELAWLR
RGAPARTCKPKFRIEAANQLIADVPPPRNTVELAKLAAARLGKDVVDLLGVSVSYQPSGGRPVLRDIEWRIGPGERIGIV
GANGAGKSTLLGLIAGTVQPGVGRVKRGKTVRLAVLDQHGDDLAPFADDRIADVLGRLRGGYQVEGREVTPTQLLERLGF
RRDQLSARVDDLSGGQRRRLQLMLTLLSEPNVLLLDEPTNDVDTEMLTATEDLLDSWAGTLIVVSHDRYLLERVTDQQYA
ILDDRLRHLPGGIDEYLQLAARVSAPAPAERPAPPAMSGAQRRATEKELAAVDRQLARLADRVAAKHTELAEHDQSDHVG
ITRLTQQLRVLQDHVAAMENRWLELSEMLE

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI69354671, Length=410, Percent_Identity=28.5365853658537, Blast_Score=146, Evalue=6e-35,
Organism=Homo sapiens, GI10947135, Length=410, Percent_Identity=28.5365853658537, Blast_Score=145, Evalue=8e-35,
Organism=Homo sapiens, GI148612853, Length=527, Percent_Identity=25.2371916508539, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI10947137, Length=386, Percent_Identity=26.9430051813472, Blast_Score=126, Evalue=6e-29,
Organism=Homo sapiens, GI27881506, Length=386, Percent_Identity=26.9430051813472, Blast_Score=126, Evalue=6e-29,
Organism=Escherichia coli, GI2367384, Length=534, Percent_Identity=32.5842696629214, Blast_Score=246, Evalue=3e-66,
Organism=Escherichia coli, GI1789751, Length=635, Percent_Identity=28.6614173228346, Blast_Score=234, Evalue=1e-62,
Organism=Escherichia coli, GI1787182, Length=514, Percent_Identity=30.7392996108949, Blast_Score=205, Evalue=9e-54,
Organism=Escherichia coli, GI1787041, Length=538, Percent_Identity=26.0223048327138, Blast_Score=169, Evalue=5e-43,
Organism=Escherichia coli, GI1788165, Length=208, Percent_Identity=34.1346153846154, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1788897, Length=534, Percent_Identity=22.4719101123595, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1786563, Length=191, Percent_Identity=30.3664921465969, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1787758, Length=178, Percent_Identity=29.7752808988764, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17553372, Length=531, Percent_Identity=29.3785310734463, Blast_Score=167, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17559834, Length=540, Percent_Identity=24.8148148148148, Blast_Score=162, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI17555318, Length=542, Percent_Identity=24.7232472324723, Blast_Score=141, Evalue=8e-34,
Organism=Caenorhabditis elegans, GI71992290, Length=177, Percent_Identity=27.683615819209, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17538654, Length=217, Percent_Identity=25.8064516129032, Blast_Score=70, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6321121, Length=406, Percent_Identity=30.2955665024631, Blast_Score=155, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6320874, Length=536, Percent_Identity=26.865671641791, Blast_Score=155, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6325030, Length=363, Percent_Identity=27.5482093663912, Blast_Score=120, Evalue=6e-28,
Organism=Saccharomyces cerevisiae, GI6324314, Length=358, Percent_Identity=25.1396648044693, Blast_Score=112, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6323278, Length=200, Percent_Identity=29.5, Blast_Score=80, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24641342, Length=526, Percent_Identity=27.7566539923954, Blast_Score=176, Evalue=3e-44,
Organism=Drosophila melanogaster, GI24666836, Length=537, Percent_Identity=27.9329608938547, Blast_Score=171, Evalue=9e-43,
Organism=Drosophila melanogaster, GI24642252, Length=526, Percent_Identity=26.8060836501901, Blast_Score=141, Evalue=1e-33,
Organism=Drosophila melanogaster, GI18859989, Length=526, Percent_Identity=26.8060836501901, Blast_Score=141, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24581191, Length=174, Percent_Identity=29.3103448275862, Blast_Score=73, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24581189, Length=174, Percent_Identity=29.3103448275862, Blast_Score=73, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24581193, Length=174, Percent_Identity=29.3103448275862, Blast_Score=73, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24581195, Length=174, Percent_Identity=29.3103448275862, Blast_Score=73, Evalue=7e-13,
Organism=Drosophila melanogaster, GI116007184, Length=197, Percent_Identity=28.9340101522843, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI221500365, Length=197, Percent_Identity=28.9340101522843, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 65023; Mature: 64892

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHLLGAEAVHLAYPTQVVFEAVTLGVNDGARIGIVGRNGDGKSSLLGLLTGQLRPDSGR
CCCCCCCCEEEEECCHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCC
VTRRSGLRVNALSQTDTLDPNRTVGWTLIGDQPEHQWAGNPRIRDVVAGLVSDIAWDTPV
EECCCCCEEEECCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCH
STLSGGQRRRVQLASLLVGEWDVIALDEPTNHLDIQGITWLADHLRRRWARNTGGLLVVT
HHHCCCHHHHHHHHHHHHCCCCEEEECCCCCCEECCHHHHHHHHHHHHHCCCCCCEEEEE
HDRWFLDEVATTTWEVHDGIVEPFEGGYAAYVLQRVERDRLTAAAEAKRQNLLRKELAWL
CCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRGAPARTCKPKFRIEAANQLIADVPPPRNTVELAKLAAARLGKDVVDLLGVSVSYQPSG
HCCCCCCCCCCCCEEHHHHHHHHCCCCCCCHHHHHHHHHHHHCHHHHHHHCCCEEECCCC
GRPVLRDIEWRIGPGERIGIVGANGAGKSTLLGLIAGTVQPGVGRVKRGKTVRLAVLDQH
CCCCHHCCCEEECCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECC
GDDLAPFADDRIADVLGRLRGGYQVEGREVTPTQLLERLGFRRDQLSARVDDLSGGQRRR
CCCCCCCCCHHHHHHHHHHCCCEEECCCCCCHHHHHHHHCCCHHHHHHHHHCCCCCHHHH
LQLMLTLLSEPNVLLLDEPTNDVDTEMLTATEDLLDSWAGTLIVVSHDRYLLERVTDQQY
HHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHCCCHH
AILDDRLRHLPGGIDEYLQLAARVSAPAPAERPAPPAMSGAQRRATEKELAAVDRQLARL
HHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
ADRVAAKHTELAEHDQSDHVGITRLTQQLRVLQDHVAAMENRWLELSEMLE
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCC
>Mature Secondary Structure 
AHLLGAEAVHLAYPTQVVFEAVTLGVNDGARIGIVGRNGDGKSSLLGLLTGQLRPDSGR
CCCCCCCEEEEECCHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCC
VTRRSGLRVNALSQTDTLDPNRTVGWTLIGDQPEHQWAGNPRIRDVVAGLVSDIAWDTPV
EECCCCCEEEECCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCH
STLSGGQRRRVQLASLLVGEWDVIALDEPTNHLDIQGITWLADHLRRRWARNTGGLLVVT
HHHCCCHHHHHHHHHHHHCCCCEEEECCCCCCEECCHHHHHHHHHHHHHCCCCCCEEEEE
HDRWFLDEVATTTWEVHDGIVEPFEGGYAAYVLQRVERDRLTAAAEAKRQNLLRKELAWL
CCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRGAPARTCKPKFRIEAANQLIADVPPPRNTVELAKLAAARLGKDVVDLLGVSVSYQPSG
HCCCCCCCCCCCCEEHHHHHHHHCCCCCCCHHHHHHHHHHHHCHHHHHHHCCCEEECCCC
GRPVLRDIEWRIGPGERIGIVGANGAGKSTLLGLIAGTVQPGVGRVKRGKTVRLAVLDQH
CCCCHHCCCEEECCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECC
GDDLAPFADDRIADVLGRLRGGYQVEGREVTPTQLLERLGFRRDQLSARVDDLSGGQRRR
CCCCCCCCCHHHHHHHHHHCCCEEECCCCCCHHHHHHHHCCCHHHHHHHHHCCCCCHHHH
LQLMLTLLSEPNVLLLDEPTNDVDTEMLTATEDLLDSWAGTLIVVSHDRYLLERVTDQQY
HHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHCCCHH
AILDDRLRHLPGGIDEYLQLAARVSAPAPAERPAPPAMSGAQRRATEKELAAVDRQLARL
HHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
ADRVAAKHTELAEHDQSDHVGITRLTQQLRVLQDHVAAMENRWLELSEMLE
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]