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The map label for this gene is PPE21 [H]

Identifier: 121637470

GI number: 121637470

Start: 1763628

End: 1765664

Strand: Reverse

Name: PPE21 [H]

Synonym: BCG_1601c

Alternate gene names: 121637470

Gene position: 1765664-1763628 (Counterclockwise)

Preceding gene: 121637483

Following gene: 121637463

Centisome position: 40.36

GC content: 62.15

Gene sequence:

>2037_bases
ATGAATTTTTCGGTGTTGCCGCCGGAGATCAATTCGGCGCTGATGTTCGCTGGTGCCGGGCCGGGACCGATGTTGGCGGC
GGCGTCGGCCTGGACCGGGCTGGCCGGCGATTTGGGTTCGGCGGCGGCCTCATTTTCGGCGGTGACCTCGCAGTTGGCCA
CCGGGTCCTGGCAAGGTCCGGCGTCAGCGGCCATGACAGGCGTGGCCGCGTCCTATGCTCGCTGGCTGACCACGGCCGCA
GCGCAGGCTGAGCAGGCGGCGGGTCAAGCCCAGGCGGCGGTATCGGCGTTCGAGGCGGCGCTGGCGGCGACGGTGCATCC
GGGCGCGGTGAGCGCCAATCGAGGTCGGTTGCGCTCCTTGGTGGCCTCGAATCTGTTGGGGCAAAACGCCCCGGCCATCG
CGGCCGTCGAGGCCGTCTATGAGCAGATGTGGGCCGCCGATGTCGCCGCGATGCTCGGTTATCACGGCGAGGCGTCGGCG
GTCGCCTTGTCGCTGACGCCGTTCACACCGTCGCCGAGCGCGGCAGCCACGCCCGGCGGTGCGGTGATCATCGCGGGGTT
TCCGTTTCTCGATCTGGGCAACGTCACCATCGGTGGCTTCAATCTGGCCAGCGGCAATCTGGGCCTCGGCAACCTGGGCA
GCTTCAACCCGGGTAGCGCCAACACGGGCAGCGTCAACTTGGGCAACGCCAATATCGGTGATCTCAACCTGGGCAGCGGC
AATATCGGCAGCTACAACCTGGGTGGCGGCAACACCGGGGATCTCAACCCGGGCAGTGGAAACACGGGCACGCTCAACTG
GGGTAGCGGAAACATCGGCAGCTATAACCTGGGCGGCGGCAACCTCGGCAGCTATAACCTGGGTAGTGGAAATACCGGCG
ACACCAACTTTGGCGGCGGTAACACCGGAAATCTCAACGTGGGTGGCGGCAACACCGGGAACTCGAATTTCGGGTTCGGA
AACACCGGTAACGTCAACTTTGGTAACGGAAACACCGGCGACACCAACTTTGGCAGCGGCAACCTTGGCAGTGGAAATAT
CGGTTTCGGCAACAAGGGCTCTCATAACATCGGGTTTGGGAACAGCGGCAACAACAACATCGGCTTCGGGCTCACCGGTG
ATAACCAGATAGGTTTCGGCGCCCTCAATTCAGGTAGCGGGAACCTCGGCTTCGGGAACTCGGGCAACGGTAATATCGGC
TTTTTCAACTCGGGCAATAACAACATCGGCATGGGAAACTCGGGCAATGGAGTCGGGGCGCTGAGCGTGGAGTTCGGCAG
TTCGGCCGAGCGCAGCTCGGGCTTCGGCAACTCCGGCGAGCTCAGTACCGGTATCGGCAACTCCGGCCAGCTCAGCACGG
GCTGGTTCAACTCGGCCACCACCAGCACCGGCTGGTTCAACTCCGGCACCACCAATACCGGCTGGTTCAACTCGGGCACC
ACGAACACCGGAATCGGAAACTCGGGCGGAAACCTGGTCACCGGCAGCATGGGTCTGTTTAACTCCGGCCATACCAACAC
GGGTAGCTTCAATGCCGGCAGCATGAACACGGGCGATTTCAACTCGGGCAACGTGAACACCGGCTACTTCAACTCCGGCA
ACATCAACACCGGCTTCTTCAACTCGGGCGATCTCAACACCGGATTGTTCAACTCGGTCAACCAGCCGGTACAGAACTCC
GGCTGGCTGCACACGGGCACCAACAACTCGGGCTACGCTAACGCCGGCACCTTCAACTCGGGCTTCGATAACAACGCCCG
TGACGAACACGCCGAATTTGTCACCGGTAACTCGGGCCTGGCCAACGTGGGCAACTACAACGCCGGCATCATCAACGTGG
GTGACCATCTGTCGGGCTTCAGAAACTCGGTACCCACGATCACCGGTACGGCCAACATTTCGGGTTTCGTCAATGCGGGA
ACCTCGATCTCTGGCTTCTTCAACTTCGGCAGCCTCATGTCGGGCTTCGCCAACTTCGACGACGAGGTCTCGGGGTATCT
CAACGGGGACAGTCGGGCGTCGGGCTGGATCCATTAG

Upstream 100 bases:

>100_bases
CCCGTCCGAAGCGCCCGGCTTTTTCGTAGGCTTCGCTGCGGTTGGGGCCAGACAGCGCCGTGAAGCCCGGTGGGTGTGGC
CGGCTGACGGGATGGTTGTG

Downstream 100 bases:

>100_bases
CGGCGCTCACGGGCGATCGTGCGGAAACCGCTGGGGGCGGTCGCCTCGCTAACTCCCCAGACATCCAGGGCCGAGCAGCT
CCTTGAGGTCACCCATCAAC

Product: PPE family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 678; Mature: 678

Protein sequence:

>678_residues
MNFSVLPPEINSALMFAGAGPGPMLAAASAWTGLAGDLGSAAASFSAVTSQLATGSWQGPASAAMTGVAASYARWLTTAA
AQAEQAAGQAQAAVSAFEAALAATVHPGAVSANRGRLRSLVASNLLGQNAPAIAAVEAVYEQMWAADVAAMLGYHGEASA
VALSLTPFTPSPSAAATPGGAVIIAGFPFLDLGNVTIGGFNLASGNLGLGNLGSFNPGSANTGSVNLGNANIGDLNLGSG
NIGSYNLGGGNTGDLNPGSGNTGTLNWGSGNIGSYNLGGGNLGSYNLGSGNTGDTNFGGGNTGNLNVGGGNTGNSNFGFG
NTGNVNFGNGNTGDTNFGSGNLGSGNIGFGNKGSHNIGFGNSGNNNIGFGLTGDNQIGFGALNSGSGNLGFGNSGNGNIG
FFNSGNNNIGMGNSGNGVGALSVEFGSSAERSSGFGNSGELSTGIGNSGQLSTGWFNSATTSTGWFNSGTTNTGWFNSGT
TNTGIGNSGGNLVTGSMGLFNSGHTNTGSFNAGSMNTGDFNSGNVNTGYFNSGNINTGFFNSGDLNTGLFNSVNQPVQNS
GWLHTGTNNSGYANAGTFNSGFDNNARDEHAEFVTGNSGLANVGNYNAGIINVGDHLSGFRNSVPTITGTANISGFVNAG
TSISGFFNFGSLMSGFANFDDEVSGYLNGDSRASGWIH

Sequences:

>Translated_678_residues
MNFSVLPPEINSALMFAGAGPGPMLAAASAWTGLAGDLGSAAASFSAVTSQLATGSWQGPASAAMTGVAASYARWLTTAA
AQAEQAAGQAQAAVSAFEAALAATVHPGAVSANRGRLRSLVASNLLGQNAPAIAAVEAVYEQMWAADVAAMLGYHGEASA
VALSLTPFTPSPSAAATPGGAVIIAGFPFLDLGNVTIGGFNLASGNLGLGNLGSFNPGSANTGSVNLGNANIGDLNLGSG
NIGSYNLGGGNTGDLNPGSGNTGTLNWGSGNIGSYNLGGGNLGSYNLGSGNTGDTNFGGGNTGNLNVGGGNTGNSNFGFG
NTGNVNFGNGNTGDTNFGSGNLGSGNIGFGNKGSHNIGFGNSGNNNIGFGLTGDNQIGFGALNSGSGNLGFGNSGNGNIG
FFNSGNNNIGMGNSGNGVGALSVEFGSSAERSSGFGNSGELSTGIGNSGQLSTGWFNSATTSTGWFNSGTTNTGWFNSGT
TNTGIGNSGGNLVTGSMGLFNSGHTNTGSFNAGSMNTGDFNSGNVNTGYFNSGNINTGFFNSGDLNTGLFNSVNQPVQNS
GWLHTGTNNSGYANAGTFNSGFDNNARDEHAEFVTGNSGLANVGNYNAGIINVGDHLSGFRNSVPTITGTANISGFVNAG
TSISGFFNFGSLMSGFANFDDEVSGYLNGDSRASGWIH
>Mature_678_residues
MNFSVLPPEINSALMFAGAGPGPMLAAASAWTGLAGDLGSAAASFSAVTSQLATGSWQGPASAAMTGVAASYARWLTTAA
AQAEQAAGQAQAAVSAFEAALAATVHPGAVSANRGRLRSLVASNLLGQNAPAIAAVEAVYEQMWAADVAAMLGYHGEASA
VALSLTPFTPSPSAAATPGGAVIIAGFPFLDLGNVTIGGFNLASGNLGLGNLGSFNPGSANTGSVNLGNANIGDLNLGSG
NIGSYNLGGGNTGDLNPGSGNTGTLNWGSGNIGSYNLGGGNLGSYNLGSGNTGDTNFGGGNTGNLNVGGGNTGNSNFGFG
NTGNVNFGNGNTGDTNFGSGNLGSGNIGFGNKGSHNIGFGNSGNNNIGFGLTGDNQIGFGALNSGSGNLGFGNSGNGNIG
FFNSGNNNIGMGNSGNGVGALSVEFGSSAERSSGFGNSGELSTGIGNSGQLSTGWFNSATTSTGWFNSGTTNTGWFNSGT
TNTGIGNSGGNLVTGSMGLFNSGHTNTGSFNAGSMNTGDFNSGNVNTGYFNSGNINTGFFNSGDLNTGLFNSVNQPVQNS
GWLHTGTNNSGYANAGTFNSGFDNNARDEHAEFVTGNSGLANVGNYNAGIINVGDHLSGFRNSVPTITGTANISGFVNAG
TSISGFFNFGSLMSGFANFDDEVSGYLNGDSRASGWIH

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PPE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002989
- InterPro:   IPR000030 [H]

Pfam domain/function: PF01469 Pentapeptide_2; PF00823 PPE [H]

EC number: NA

Molecular weight: Translated: 66679; Mature: 66679

Theoretical pI: Translated: 4.19; Mature: 4.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFSVLPPEINSALMFAGAGPGPMLAAASAWTGLAGDLGSAAASFSAVTSQLATGSWQGP
CCCCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
ASAAMTGVAASYARWLTTAAAQAEQAAGQAQAAVSAFEAALAATVHPGAVSANRGRLRSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHH
VASNLLGQNAPAIAAVEAVYEQMWAADVAAMLGYHGEASAVALSLTPFTPSPSAAATPGG
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCC
AVIIAGFPFLDLGNVTIGGFNLASGNLGLGNLGSFNPGSANTGSVNLGNANIGDLNLGSG
EEEEECCCCEEECCEEECCEEECCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCEECCCC
NIGSYNLGGGNTGDLNPGSGNTGTLNWGSGNIGSYNLGGGNLGSYNLGSGNTGDTNFGGG
CCCEEECCCCCCCCCCCCCCCCEEEECCCCCCCEEECCCCCCCCEECCCCCCCCCCCCCC
NTGNLNVGGGNTGNSNFGFGNTGNVNFGNGNTGDTNFGSGNLGSGNIGFGNKGSHNIGFG
CCCEEECCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NSGNNNIGFGLTGDNQIGFGALNSGSGNLGFGNSGNGNIGFFNSGNNNIGMGNSGNGVGA
CCCCCCEEEEECCCCCCCEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEE
LSVEFGSSAERSSGFGNSGELSTGIGNSGQLSTGWFNSATTSTGWFNSGTTNTGWFNSGT
EEEECCCCCHHHCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TNTGIGNSGGNLVTGSMGLFNSGHTNTGSFNAGSMNTGDFNSGNVNTGYFNSGNINTGFF
CCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCEE
NSGDLNTGLFNSVNQPVQNSGWLHTGTNNSGYANAGTFNSGFDNNARDEHAEFVTGNSGL
CCCCCCCHHHHHCCCCHHCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCC
ANVGNYNAGIINVGDHLSGFRNSVPTITGTANISGFVNAGTSISGFFNFGSLMSGFANFD
CCCCCCCCCEEECCHHHHHHHHCCCEEEECCCCCEEEECCCCEEHHHHHHHHHHHHHCCC
DEVSGYLNGDSRASGWIH
CHHCEEECCCCCCCCCCC
>Mature Secondary Structure
MNFSVLPPEINSALMFAGAGPGPMLAAASAWTGLAGDLGSAAASFSAVTSQLATGSWQGP
CCCCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
ASAAMTGVAASYARWLTTAAAQAEQAAGQAQAAVSAFEAALAATVHPGAVSANRGRLRSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHH
VASNLLGQNAPAIAAVEAVYEQMWAADVAAMLGYHGEASAVALSLTPFTPSPSAAATPGG
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCC
AVIIAGFPFLDLGNVTIGGFNLASGNLGLGNLGSFNPGSANTGSVNLGNANIGDLNLGSG
EEEEECCCCEEECCEEECCEEECCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCEECCCC
NIGSYNLGGGNTGDLNPGSGNTGTLNWGSGNIGSYNLGGGNLGSYNLGSGNTGDTNFGGG
CCCEEECCCCCCCCCCCCCCCCEEEECCCCCCCEEECCCCCCCCEECCCCCCCCCCCCCC
NTGNLNVGGGNTGNSNFGFGNTGNVNFGNGNTGDTNFGSGNLGSGNIGFGNKGSHNIGFG
CCCEEECCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NSGNNNIGFGLTGDNQIGFGALNSGSGNLGFGNSGNGNIGFFNSGNNNIGMGNSGNGVGA
CCCCCCEEEEECCCCCCCEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEE
LSVEFGSSAERSSGFGNSGELSTGIGNSGQLSTGWFNSATTSTGWFNSGTTNTGWFNSGT
EEEECCCCCHHHCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TNTGIGNSGGNLVTGSMGLFNSGHTNTGSFNAGSMNTGDFNSGNVNTGYFNSGNINTGFF
CCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCEE
NSGDLNTGLFNSVNQPVQNSGWLHTGTNNSGYANAGTFNSGFDNNARDEHAEFVTGNSGL
CCCCCCCHHHHHCCCCHHCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCC
ANVGNYNAGIINVGDHLSGFRNSVPTITGTANISGFVNAGTSISGFFNFGSLMSGFANFD
CCCCCCCCCEEECCHHHHHHHHCCCEEEECCCCCEEEECCCCEEHHHHHHHHHHHHHCCC
DEVSGYLNGDSRASGWIH
CHHCEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]