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The map label for this gene is devB

Identifier: 121637375

GI number: 121637375

Start: 1648526

End: 1649269

Strand: Reverse

Name: devB

Synonym: BCG_1506c

Alternate gene names: 121637375

Gene position: 1649269-1648526 (Counterclockwise)

Preceding gene: 121637376

Following gene: 121637374

Centisome position: 37.7

GC content: 67.88

Gene sequence:

>744_bases
GTGAGCAGTAGCATCGAGATCTTCCCCGATAGCGACATTCTGGTCGCGGCCGCGGGTAAGCGCTTGGTTGGCGCCATCGG
GGCCGCGGTGGCGGCCAGAGGGCAGGCGCTGATCGTGCTGACCGGGGGCGGCAACGGGATTGCGCTTCTGCGCTACCTCA
GCGCCCAAGCACAGCAGATTGAATGGTCCAAGGTGCACCTGTTCTGGGGCGACGAACGCTACGTTCCCGAAGACGATGAC
GAGCGCAATCTCAAGCAGGCCCGGCGGGCGTTGCTCAATCACGTCGACATTCCATCGAACCAGGTGCACCCGATGGCCGC
CAGTGATGGTGACTTCGGCGGCGATCTGGACGCCGCGGCCCTGGCCTACGAACAGGTGCTGGCCGCCAGTGCCGCACCAG
GTGACCCGGCGCCGAATTTCGACGTCCACCTGCTGGGCATGGGGCCCGAGGGCCACATTAACTCGCTGTTCCCGCACAGC
CCCGCCGTCCTCGAGAGCACCCGCATGGTGGTGGCGGTCGACGACTCGCCGAAACCGCCGCCACGCCGAATCACCTTGAC
CCTGCCGGCGATTCAGCGTTCCCGCGAGGTGTGGCTGCTGGTTTCCGGGCCGGGTAAGGCCGACGCCGTGGCCGCGGCCA
TCGGCGGCGCCGATCCGGTTTCGGTACCGGCGGCCGGGGCCGTCGGGCGTCAGAACACGCTCTGGCTGCTGGACCGCGAC
GCCGCCGCCAAGCTTCCGAGTTAA

Upstream 100 bases:

>100_bases
GCAGGGTAACCGGTGAGTGCCTAGCCGAAGACCTGCGCCGGCTGGACCCCGACGAAATCTACTGCGCCGCGCTCGAGGGA
ATCAAGAAGGTGCAGTACCG

Downstream 100 bases:

>100_bases
CCGCGTCAGGGTCATAATGACCGTCATGGCAGACAGAAGCGGCCGCCCCGCGCCCGTGCGACGGCGAATGAAAACCCTCA
CCCAGGCCGCATTGAACGCC

Product: putative 6-phosphogluconolactonase devB

Products: NA

Alternate protein names: 6PGL

Number of amino acids: Translated: 247; Mature: 246

Protein sequence:

>247_residues
MSSSIEIFPDSDILVAAAGKRLVGAIGAAVAARGQALIVLTGGGNGIALLRYLSAQAQQIEWSKVHLFWGDERYVPEDDD
ERNLKQARRALLNHVDIPSNQVHPMAASDGDFGGDLDAAALAYEQVLAASAAPGDPAPNFDVHLLGMGPEGHINSLFPHS
PAVLESTRMVVAVDDSPKPPPRRITLTLPAIQRSREVWLLVSGPGKADAVAAAIGGADPVSVPAAGAVGRQNTLWLLDRD
AAAKLPS

Sequences:

>Translated_247_residues
MSSSIEIFPDSDILVAAAGKRLVGAIGAAVAARGQALIVLTGGGNGIALLRYLSAQAQQIEWSKVHLFWGDERYVPEDDD
ERNLKQARRALLNHVDIPSNQVHPMAASDGDFGGDLDAAALAYEQVLAASAAPGDPAPNFDVHLLGMGPEGHINSLFPHS
PAVLESTRMVVAVDDSPKPPPRRITLTLPAIQRSREVWLLVSGPGKADAVAAAIGGADPVSVPAAGAVGRQNTLWLLDRD
AAAKLPS
>Mature_246_residues
SSSIEIFPDSDILVAAAGKRLVGAIGAAVAARGQALIVLTGGGNGIALLRYLSAQAQQIEWSKVHLFWGDERYVPEDDDE
RNLKQARRALLNHVDIPSNQVHPMAASDGDFGGDLDAAALAYEQVLAASAAPGDPAPNFDVHLLGMGPEGHINSLFPHSP
AVLESTRMVVAVDDSPKPPPRRITLTLPAIQRSREVWLLVSGPGKADAVAAAIGGADPVSVPAAGAVGRQNTLWLLDRDA
AAKLPS

Specific function: Hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily

Homologues:

Organism=Homo sapiens, GI52145310, Length=234, Percent_Identity=33.7606837606838, Blast_Score=116, Evalue=2e-26,
Organism=Homo sapiens, GI6912586, Length=252, Percent_Identity=32.9365079365079, Blast_Score=104, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI115533058, Length=249, Percent_Identity=30.1204819277108, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI115533060, Length=249, Percent_Identity=30.1204819277108, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6324362, Length=205, Percent_Identity=32.1951219512195, Blast_Score=97, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6319918, Length=206, Percent_Identity=32.5242718446602, Blast_Score=93, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6321957, Length=253, Percent_Identity=26.8774703557312, Blast_Score=92, Evalue=7e-20,
Organism=Saccharomyces cerevisiae, GI6321687, Length=259, Percent_Identity=28.957528957529, Blast_Score=86, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24641119, Length=213, Percent_Identity=36.150234741784, Blast_Score=106, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): 6PGL_MYCBO (P63339)

Other databases:

- EMBL:   BX248339
- RefSeq:   NP_855132.1
- ProteinModelPortal:   P63339
- SMR:   P63339
- EnsemblBacteria:   EBMYCT00000017677
- GeneID:   1092337
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb1480c
- GeneTree:   EBGT00050000017647
- HOGENOM:   HBG725991
- OMA:   PAICLTG
- ProtClustDB:   CLSK791167
- BioCyc:   MBOV233413:MB1480C-MONOMER
- BRENDA:   3.1.1.31
- InterPro:   IPR005900
- InterPro:   IPR006148
- PANTHER:   PTHR11054
- TIGRFAMs:   TIGR01198

Pfam domain/function: PF01182 Glucosamine_iso

EC number: =3.1.1.31

Molecular weight: Translated: 25804; Mature: 25673

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSSIEIFPDSDILVAAAGKRLVGAIGAAVAARGQALIVLTGGGNGIALLRYLSAQAQQI
CCCCEEEECCCCEEEEECCCHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCC
EWSKVHLFWGDERYVPEDDDERNLKQARRALLNHVDIPSNQVHPMAASDGDFGGDLDAAA
EEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCCHHHHH
LAYEQVLAASAAPGDPAPNFDVHLLGMGPEGHINSLFPHSPAVLESTRMVVAVDDSPKPP
HHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCEECCCEEEEEECCCCCCC
PRRITLTLPAIQRSREVWLLVSGPGKADAVAAAIGGADPVSVPAAGAVGRQNTLWLLDRD
CCEEEEEECCCCCCCEEEEEEECCCCCHHEEEECCCCCCCCCCCCCCCCCCCEEEEEECC
AAAKLPS
HHCCCCC
>Mature Secondary Structure 
SSSIEIFPDSDILVAAAGKRLVGAIGAAVAARGQALIVLTGGGNGIALLRYLSAQAQQI
CCCEEEECCCCEEEEECCCHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCC
EWSKVHLFWGDERYVPEDDDERNLKQARRALLNHVDIPSNQVHPMAASDGDFGGDLDAAA
EEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCCHHHHH
LAYEQVLAASAAPGDPAPNFDVHLLGMGPEGHINSLFPHSPAVLESTRMVVAVDDSPKPP
HHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCEECCCEEEEEECCCCCCC
PRRITLTLPAIQRSREVWLLVSGPGKADAVAAAIGGADPVSVPAAGAVGRQNTLWLLDRD
CCEEEEEECCCCCCCEEEEEEECCCCCHHEEEECCCCCCCCCCCCCCCCCCCEEEEEECC
AAAKLPS
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972