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The map label for this gene is PE_PGRS25 [H]

Identifier: 121637326

GI number: 121637326

Start: 1597287

End: 1598645

Strand: Reverse

Name: PE_PGRS25 [H]

Synonym: BCG_1457c

Alternate gene names: 121637326

Gene position: 1598645-1597287 (Counterclockwise)

Preceding gene: 121637327

Following gene: 121637324

Centisome position: 36.54

GC content: 78.51

Gene sequence:

>1359_bases
ATGTCGTTTTTGTTTGCACAGCCGGAAATGCTGGGCGCGGCGGCGACGGATCTGGCAAGCATCGGCTCGGCGATCAGCAC
GGCCAATGCTGCGGCCGCGGCCGCCACGACGCGTGTGCTGGCCGCCGGTGCCGATGAGGTGTCCGCCGCCGTGGCGGCGC
TGTTTAGCGGCCACGCGCAGACCTATCAGGCGCTGAGCACTCAGGCGGCGGCGTTTCACCAGCAGATCGTGCAGACCCTC
ACGAGCACGGCAGGCGCGTATGCCAGCGCCGAGGCCGCCAACGTCGAGCAGCAGCTGCTGGGTGCGATCAACGCGCCGAC
CATGGCGCTGCTGGGGCGCCCGCTGATCGGCCACGGCGCCGACGGGGCGCCGGGGACCGGGCAGGCCGGCGGGGCCGGCG
GGATCCTGTACGGCAACGGCGGCAACGGCGGGTCCGGCGCCACCGGTCAGGCCGGCGGTGCGGGCGGGGCGGCCGGGCTG
ATCGGCCACGGCGGGGCCGGCGGCCTGGGTGGCACCGGCGCGTCCGGTGGTGCCGGCGGGGCCGGCGGATGGCTGTGGGG
CAACGGCGGGGCCGGCGGCAATGGCGGGGTCGGGGTGGCCGGCGACCCCGGTGGTGTCGGCGGTGCCGGCGGTGCCGGCG
GCGCCGCCGGATTGTGGGGCAGCGGAGGGTCCGGCGGCACCGGCGGGCAAGGGGGGGTCGGTGGCGGCAAGTCCGGCGAC
GGCGGCACGGGGGGTATCGGCGGCGCCGGTGGCGGTGGTGGCTGGCTGCACGGCGACGGCGGCGCCGGCGGACACGGCGG
GCAGGGCGGAACCGGCGTCAGCTCAGGAGGCAACGGCGGGGCCGGCGGCACCGGCGGCGACGGCCGCGGCCTGTCGGGCA
GCGGCGGGGCCGGCGGGCACGGCGGGCAAACTGGGGTTGGAGGCAAAGTCGGGGAGAATAACTTCGGGGGCGCGGGCGGT
GCCGGCGGTACCGGCGGGCTCATCGGCAACGGCGGTGCCGGCGGCACCGGCGGCAAGGGCGGCGACGGCTTCGGCGTGTT
CGGCAAGGGCGGCGCCGGCGGGACCGGCGGGCGAGGCGGTGCCGCCGGCCTGATCGGCGACGCCGGGACCGGCGGGACCG
GCGGAAAGGGCGGCACCGCCGGCGAGGACGGTACCGGCGGCAACGGCGGGACCGGCGGAAACGGTGGGGCCGCCGTCCTA
ATCGGCAACGGCGGGGGCGGCGGCGCCGGCGGAAACGGTGGGGCCGGCAACGATGGCACCCCCGGCAACGGCGGGGGCGG
CGGCGTCGGCGGGACCGGGGGAACCCTGTTCGGCCAGCCCGGCCAACCCGGTCCGCCCGGCCAGCCCGGCCCCGCCTAA

Upstream 100 bases:

>100_bases
ACGTTTCTATAACATTACCAATGATGGCCTATATCACCTGCGCTTATGCTGCACGATCACGACAAGTCTGCTCATACCCA
CAGGATTCAGGGGGACGGTC

Downstream 100 bases:

>100_bases
CCCGACCAAACCGACGCGGGCCGCGAAACCCTGAAAAGGGCTGGTCTACCCGCGGCGCGAATATTCGCTGGGCGCAACGC
CATACCAGCGTTTGAACGCA

Product: PE-PGRS family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MSFLFAQPEMLGAAATDLASIGSAISTANAAAAAATTRVLAAGADEVSAAVAALFSGHAQTYQALSTQAAAFHQQIVQTL
TSTAGAYASAEAANVEQQLLGAINAPTMALLGRPLIGHGADGAPGTGQAGGAGGILYGNGGNGGSGATGQAGGAGGAAGL
IGHGGAGGLGGTGASGGAGGAGGWLWGNGGAGGNGGVGVAGDPGGVGGAGGAGGAAGLWGSGGSGGTGGQGGVGGGKSGD
GGTGGIGGAGGGGGWLHGDGGAGGHGGQGGTGVSSGGNGGAGGTGGDGRGLSGSGGAGGHGGQTGVGGKVGENNFGGAGG
AGGTGGLIGNGGAGGTGGKGGDGFGVFGKGGAGGTGGRGGAAGLIGDAGTGGTGGKGGTAGEDGTGGNGGTGGNGGAAVL
IGNGGGGGAGGNGGAGNDGTPGNGGGGGVGGTGGTLFGQPGQPGPPGQPGPA

Sequences:

>Translated_452_residues
MSFLFAQPEMLGAAATDLASIGSAISTANAAAAAATTRVLAAGADEVSAAVAALFSGHAQTYQALSTQAAAFHQQIVQTL
TSTAGAYASAEAANVEQQLLGAINAPTMALLGRPLIGHGADGAPGTGQAGGAGGILYGNGGNGGSGATGQAGGAGGAAGL
IGHGGAGGLGGTGASGGAGGAGGWLWGNGGAGGNGGVGVAGDPGGVGGAGGAGGAAGLWGSGGSGGTGGQGGVGGGKSGD
GGTGGIGGAGGGGGWLHGDGGAGGHGGQGGTGVSSGGNGGAGGTGGDGRGLSGSGGAGGHGGQTGVGGKVGENNFGGAGG
AGGTGGLIGNGGAGGTGGKGGDGFGVFGKGGAGGTGGRGGAAGLIGDAGTGGTGGKGGTAGEDGTGGNGGTGGNGGAAVL
IGNGGGGGAGGNGGAGNDGTPGNGGGGGVGGTGGTLFGQPGQPGPPGQPGPA
>Mature_451_residues
SFLFAQPEMLGAAATDLASIGSAISTANAAAAAATTRVLAAGADEVSAAVAALFSGHAQTYQALSTQAAAFHQQIVQTLT
STAGAYASAEAANVEQQLLGAINAPTMALLGRPLIGHGADGAPGTGQAGGAGGILYGNGGNGGSGATGQAGGAGGAAGLI
GHGGAGGLGGTGASGGAGGAGGWLWGNGGAGGNGGVGVAGDPGGVGGAGGAGGAAGLWGSGGSGGTGGQGGVGGGKSGDG
GTGGIGGAGGGGGWLHGDGGAGGHGGQGGTGVSSGGNGGAGGTGGDGRGLSGSGGAGGHGGQTGVGGKVGENNFGGAGGA
GGTGGLIGNGGAGGTGGKGGDGFGVFGKGGAGGTGGRGGAAGLIGDAGTGGTGGKGGTAGEDGTGGNGGTGGNGGAAVLI
GNGGGGGAGGNGGAGNDGTPGNGGGGGVGGTGGTLFGQPGQPGPPGQPGPA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PE family. PGRS subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000084 [H]

Pfam domain/function: PF00934 PE [H]

EC number: NA

Molecular weight: Translated: 37966; Mature: 37835

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFLFAQPEMLGAAATDLASIGSAISTANAAAAAATTRVLAAGADEVSAAVAALFSGHAQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCHHH
TYQALSTQAAAFHQQIVQTLTSTAGAYASAEAANVEQQLLGAINAPTMALLGRPLIGHGA
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCC
DGAPGTGQAGGAGGILYGNGGNGGSGATGQAGGAGGAAGLIGHGGAGGLGGTGASGGAGG
CCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCC
AGGWLWGNGGAGGNGGVGVAGDPGGVGGAGGAGGAAGLWGSGGSGGTGGQGGVGGGKSGD
CCCCEECCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GGTGGIGGAGGGGGWLHGDGGAGGHGGQGGTGVSSGGNGGAGGTGGDGRGLSGSGGAGGH
CCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GGQTGVGGKVGENNFGGAGGAGGTGGLIGNGGAGGTGGKGGDGFGVFGKGGAGGTGGRGG
CCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCEEEECCCCCCCCCCCC
AAGLIGDAGTGGTGGKGGTAGEDGTGGNGGTGGNGGAAVLIGNGGGGGAGGNGGAGNDGT
CCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCC
PGNGGGGGVGGTGGTLFGQPGQPGPPGQPGPA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SFLFAQPEMLGAAATDLASIGSAISTANAAAAAATTRVLAAGADEVSAAVAALFSGHAQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCHHH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CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]