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The map label for this gene is dapE [H]

Identifier: 121637131

GI number: 121637131

Start: 1374979

End: 1376043

Strand: Direct

Name: dapE [H]

Synonym: BCG_1262

Alternate gene names: 121637131

Gene position: 1374979-1376043 (Clockwise)

Preceding gene: 121637129

Following gene: 121637134

Centisome position: 31.43

GC content: 66.57

Gene sequence:

>1065_bases
GTGCTGGATTTGCGCGGGGACCCGATCGAATTGACCGCGGCGCTGATTGACATCCCCAGCGAGTCGAGGAAGGAGGCACG
CATCGCCGACGAGGTGGAAGCGGCGTTGCGCGCTCAGGCATCGGGGTTCGAGATCATCCGCAACGGCAACGCGGTGCTGG
CGCGTACAAAGCTGAACCGGTCCTCGCGGGTGCTGTTGGCCGGACACCTGGACACCGTGCCAGTGGCCGGCAACCTGCCT
AGCCGCCGCGAGAACGACCAGCTGCACGGCTGCGGCGCAGCCGACATGAAATCCGGCGACGCGGTCTTCCTTCATCTGGC
CGCTACACTGGCCGAACCGACGCACGATCTAACACTGGTGTTCTACGACTGCGAGGAAATCGATTCGGCGGCAAACGGTT
TAGGCCGCATCCAGCGCGAGCTGCCGGACTGGCTATCCGCGGATGTAGCCATCTTGGGTGAGCCCACCGCCGGCTGCATC
GAGGCTGGTTGCCAGGGCACGTTGCGTGTCGTCCTCAGCGTGACCGGAACTCGCGCGCATTCAGCGCGTTCGTGGTTGGG
TGACAACGCAATCCACAAGTTGGGTGCTGTGCTGGACCGGTTGGCCGTCTACCGGGCACGCAGCGTCGACATCGACGGTT
GCACCTATCGGGAGGGCCTCTCGGCGGTGCGCGTAGCAGGCGGCGTCGCCGGCAACGTGATCCCTGACGCGGCCTCGGTC
ACGATCAACTACCGCTTTGCCCCCGACCGGTCGGTGGCCGCGGCATTGCAACATGTCCATGACGTGTTCGACGGGCTCGA
CGTGCAGATCGAGCAGACGGACGCCGCGGCCGGTGCGCTGCCTGGCCTGTCCGAGCCCGCGGCCAAGGCGCTGGTCGAGG
CCGCCGGCGGGCAGGTCCGGGCCAAGTATGGCTGGACTGATGTGTCGCGCTTTGCCGCTTTGGGCATACCGGCGGTCAAT
TACGGCCCAGGTGATCCCAACCTGGCGCACTGCCGCGACGAACGGGTGCCCGTCGGCAACATCACCGCGGCCGTGGACTT
GCTGCGCCGATACCTGGGTGGCTAG

Upstream 100 bases:

>100_bases
CGGTCGACACGCTACTTGTGCCGCCGAACAGACACAAAACCACCCTATTTCGACCAGAATCGGGTGCTTTTGCGTCTGCT
CGGCCAACTAAGCTAGCGCC

Downstream 100 bases:

>100_bases
CGCTGCTGTGGCCCCAAGCGTGCTGCCGCCTTGGTCGCGTCGGCTGCCGCGGCTGCCATCCCGATCCCGGCCAGCTCCTC
AGCCACCGCGGTCAGCTCGG

Product: succinyl-diaminopimelate desuccinylase

Products: NA

Alternate protein names: SDAP desuccinylase [H]

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MLDLRGDPIELTAALIDIPSESRKEARIADEVEAALRAQASGFEIIRNGNAVLARTKLNRSSRVLLAGHLDTVPVAGNLP
SRRENDQLHGCGAADMKSGDAVFLHLAATLAEPTHDLTLVFYDCEEIDSAANGLGRIQRELPDWLSADVAILGEPTAGCI
EAGCQGTLRVVLSVTGTRAHSARSWLGDNAIHKLGAVLDRLAVYRARSVDIDGCTYREGLSAVRVAGGVAGNVIPDAASV
TINYRFAPDRSVAAALQHVHDVFDGLDVQIEQTDAAAGALPGLSEPAAKALVEAAGGQVRAKYGWTDVSRFAALGIPAVN
YGPGDPNLAHCRDERVPVGNITAAVDLLRRYLGG

Sequences:

>Translated_354_residues
MLDLRGDPIELTAALIDIPSESRKEARIADEVEAALRAQASGFEIIRNGNAVLARTKLNRSSRVLLAGHLDTVPVAGNLP
SRRENDQLHGCGAADMKSGDAVFLHLAATLAEPTHDLTLVFYDCEEIDSAANGLGRIQRELPDWLSADVAILGEPTAGCI
EAGCQGTLRVVLSVTGTRAHSARSWLGDNAIHKLGAVLDRLAVYRARSVDIDGCTYREGLSAVRVAGGVAGNVIPDAASV
TINYRFAPDRSVAAALQHVHDVFDGLDVQIEQTDAAAGALPGLSEPAAKALVEAAGGQVRAKYGWTDVSRFAALGIPAVN
YGPGDPNLAHCRDERVPVGNITAAVDLLRRYLGG
>Mature_354_residues
MLDLRGDPIELTAALIDIPSESRKEARIADEVEAALRAQASGFEIIRNGNAVLARTKLNRSSRVLLAGHLDTVPVAGNLP
SRRENDQLHGCGAADMKSGDAVFLHLAATLAEPTHDLTLVFYDCEEIDSAANGLGRIQRELPDWLSADVAILGEPTAGCI
EAGCQGTLRVVLSVTGTRAHSARSWLGDNAIHKLGAVLDRLAVYRARSVDIDGCTYREGLSAVRVAGGVAGNVIPDAASV
TINYRFAPDRSVAAALQHVHDVFDGLDVQIEQTDAAAGALPGLSEPAAKALVEAAGGQVRAKYGWTDVSRFAALGIPAVN
YGPGDPNLAHCRDERVPVGNITAAVDLLRRYLGG

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; fifth step. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650
- InterPro:   IPR010174 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.18 [H]

Molecular weight: Translated: 37273; Mature: 37273

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS00758 ARGE_DAPE_CPG2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDLRGDPIELTAALIDIPSESRKEARIADEVEAALRAQASGFEIIRNGNAVLARTKLNR
CCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEEEECCC
SSRVLLAGHLDTVPVAGNLPSRRENDQLHGCGAADMKSGDAVFLHLAATLAEPTHDLTLV
CCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHCCCCCCEEEE
FYDCEEIDSAANGLGRIQRELPDWLSADVAILGEPTAGCIEAGCQGTLRVVLSVTGTRAH
EEEHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHCCCCEEEEEEEECCCCHH
SARSWLGDNAIHKLGAVLDRLAVYRARSVDIDGCTYREGLSAVRVAGGVAGNVIPDAASV
HHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEE
TINYRFAPDRSVAAALQHVHDVFDGLDVQIEQTDAAAGALPGLSEPAAKALVEAAGGQVR
EEEEEECCCHHHHHHHHHHHHHHCCCCEEEECCCCHHCCCCCCCCHHHHHHHHHCCCEEE
AKYGWTDVSRFAALGIPAVNYGPGDPNLAHCRDERVPVGNITAAVDLLRRYLGG
EECCCCHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLDLRGDPIELTAALIDIPSESRKEARIADEVEAALRAQASGFEIIRNGNAVLARTKLNR
CCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEEEECCC
SSRVLLAGHLDTVPVAGNLPSRRENDQLHGCGAADMKSGDAVFLHLAATLAEPTHDLTLV
CCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHCCCCCCEEEE
FYDCEEIDSAANGLGRIQRELPDWLSADVAILGEPTAGCIEAGCQGTLRVVLSVTGTRAH
EEEHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHCCCCEEEEEEEECCCCHH
SARSWLGDNAIHKLGAVLDRLAVYRARSVDIDGCTYREGLSAVRVAGGVAGNVIPDAASV
HHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEE
TINYRFAPDRSVAAALQHVHDVFDGLDVQIEQTDAAAGALPGLSEPAAKALVEAAGGQVR
EEEEEECCCHHHHHHHHHHHHHHCCCCEEEECCCCHHCCCCCCCCHHHHHHHHHCCCEEE
AKYGWTDVSRFAALGIPAVNYGPGDPNLAHCRDERVPVGNITAAVDLLRRYLGG
EECCCCHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7881553; 12948626; 7592354 [H]