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The map label for this gene is 121637017

Identifier: 121637017

GI number: 121637017

Start: 1245465

End: 1245785

Strand: Direct

Name: 121637017

Synonym: BCG_1146

Alternate gene names: NA

Gene position: 1245465-1245785 (Clockwise)

Preceding gene: 121637016

Following gene: 121637018

Centisome position: 28.47

GC content: 64.17

Gene sequence:

>321_bases
TTGCCGTGCGTGGGCTACGGCGACCGTCGCGAATTCGTCGACGCGGTGGCCGTAGAAGCCATCTGCGAAAACCTGAATAC
CTCGGGGCAACCCGATCCCGACCTGGTGATCCGCACCTCGGGGGAACAACGCTTGTCCGGCCACCGAGGGCCCACTGGCG
GAGTTTCGCGACGTCGACTTCTGCGCGCGCTGCGTGACTACAGTACGCCACACGCGTCGATCCCCTACGTTCCGCCGCCC
TATCGAAGCGACGGGATCCACGCTTCCCGGCTGGCGGTTGAATCGGTTTTCGATGCATTGGCTGGGCGCGTCGAACTCTA
A

Upstream 100 bases:

>100_bases
GCGTCTACTACAGCTTGCGCAGCCGTAGCCGCTTGATGGCATCGGACTGGTTACCGTCTGCCTGCTGTCCACAGAAAACC
TGTGTGCGATCCCGACGAGC

Downstream 100 bases:

>100_bases
AGACTTTATGGAAATTAGTTGTACAGTGATAAAACCGTTATAGGGTCCGTTGTCAAACAATGATAATCACGTGATAGGAA
CGTGATTCATCGGTCTGAAG

Product: hypothetical protein

Products: NA

Alternate protein names: (2Z,6E)-farnesyl diphosphate synthase; Z-FPP synthase; Z-isoprenyl diphosphate synthase [H]

Number of amino acids: Translated: 106; Mature: 105

Protein sequence:

>106_residues
MPCVGYGDRREFVDAVAVEAICENLNTSGQPDPDLVIRTSGEQRLSGHRGPTGGVSRRRLLRALRDYSTPHASIPYVPPP
YRSDGIHASRLAVESVFDALAGRVEL

Sequences:

>Translated_106_residues
MPCVGYGDRREFVDAVAVEAICENLNTSGQPDPDLVIRTSGEQRLSGHRGPTGGVSRRRLLRALRDYSTPHASIPYVPPP
YRSDGIHASRLAVESVFDALAGRVEL
>Mature_105_residues
PCVGYGDRREFVDAVAVEAICENLNTSGQPDPDLVIRTSGEQRLSGHRGPTGGVSRRRLLRALRDYSTPHASIPYVPPPY
RSDGIHASRLAVESVFDALAGRVEL

Specific function: Generates Z-farnesyl diphosphate (Z-FPP) from isopentenyl pyrophosphate (IPP). Z-FPP is the precursor of decaprenyl diphosphate, which has a central role in the biosynthesis of the mycobacterial cell wall [H]

COG id: COG0020

COG function: function code I; Undecaprenyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPP synthase family. Z-FPP synthase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001441
- InterPro:   IPR018520 [H]

Pfam domain/function: PF01255 Prenyltransf [H]

EC number: =2.5.1.68 [H]

Molecular weight: Translated: 11544; Mature: 11413

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPCVGYGDRREFVDAVAVEAICENLNTSGQPDPDLVIRTSGEQRLSGHRGPTGGVSRRRL
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHHCCCCCCCCCHHHHHH
LRALRDYSTPHASIPYVPPPYRSDGIHASRLAVESVFDALAGRVEL
HHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PCVGYGDRREFVDAVAVEAICENLNTSGQPDPDLVIRTSGEQRLSGHRGPTGGVSRRRL
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHHCCCCCCCCCHHHHHH
LRALRDYSTPHASIPYVPPPYRSDGIHASRLAVESVFDALAGRVEL
HHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]