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The map label for this gene is kdpA

Identifier: 121636959

GI number: 121636959

Start: 1182497

End: 1184212

Strand: Direct

Name: kdpA

Synonym: BCG_1087

Alternate gene names: 121636959

Gene position: 1182497-1184212 (Clockwise)

Preceding gene: 121636958

Following gene: 121636960

Centisome position: 27.03

GC content: 63.46

Gene sequence:

>1716_bases
ATGTCCGGGACGAGTTGGTTGCAGTTCGCGGCGTTGATCGCGGTGCTGTTGCTCACCGCGCCAGCGCTGGGCGGCTACCT
GGCCAAGATCTACGGCGACGAGGCCAAAAAGCCCGGCGATCGGGTGTTTGGGCCGATCGAGCGCGTGATCTACCAGGTAT
GCCGAGTCGATCCCGGCAGCGAGCAACGGTGGAGCACCTATGCCCTGTCCGTGCTTGCGTTCAGTGTTATGTCCTTCCTG
CTGCTGTATGGGATCGCGCGGTTTCAGGGCGTGCTGCCGTTCAATCCGACGGACAAGCCGGCGGTGACCGACCATGTCGC
CTTCAACGCCGCGGTCAGCTTCATGACCAATACCAACTGGCAGTCCTACAGCGGCGAAGCCACGATGAGCCACTTCACCC
AGATGACCGGGCTGGCCGTGCAGAACTTCGTCTCCGCGTCCGCCGGCATGTGCGTGCTGGCGGCCCTGATCAGAGGTCTG
GCCCGCAAACGGGCGAGCACGCTCGGCAACTTCTGGGTAGACCTCGCCCGCACCGTGTTGCGCATCATGTTTCCGCTGTC
GTTCGTGGTGGCGATCCTGTTGGTCAGCCAGGGCGTGATCCAGAACCTGCATGGTTTCATCGTCGCCAACACGCTGGAGG
GCGCCCCCCAGCTCATTCCAGGCGGGCCGGTGGCCAGCCAGGTCGCGATCAAGCAGCTCGGCACCAACGGCGGCGGGTTC
TTCAACGTGAACTCCGCGCATCCGTTCGAAAACTACACGCCGATAGGCAATTTCGTCGAAAACTGGGCGATCCTGATCAT
CCCGTTCGCGCTGTGCTTCGCCTTCGGCAAGATGGTGCACGACCGTCGTCAAGGCTGGGCGGTGCTGGCCATCATGGGCA
TCATTTGGATCGGAATGTCAGTCGCGGCAATGTCATTCGAGGCCAAGGGCAACCCGCGGCTGGATGCGCTGGGGGTGACA
CAGCAGACGACGGTCGACCAGTCCGGCGGCAACCTGGAGGGCAAGGAGGTGCGCTTTGGCGTCGGTGCGTCTGGGTTATG
GGCGGCGTCGACGACCGGCACCTCCAACGGCTCGGTCAACTCGATGCACGACAGCTACACACCACTGGGCGGCATGGTCC
CGCTGGCGCACATGATGCTCGGCGAAGTCAGCCCGGGCGGCACCGGCGTCGGATTGAACGGCCTACTGGTCATGGCGATC
CTGGCGGTTTTCATCGCCGGCCTCATGGTAGGCCGGACACCGGAGTATCTCGGCAAGAAGATCCAGGCCACCGAGATGAA
GCTGGTGACGCTCTACATCCTGGCGATGCCCATCGCCCTGCTGAGTTTCGCCGCCGCGTCGGTGCTGATCTCCTCCGCGC
TGGCGTCGCGGAACAACCCTGGGCCGCATGGTCTTTCGGAGATTCTATACGCCTACACGTCGGGCGCGAACAACAACGGG
TCGGCCTTTGCCGGTCTGACCGCGTCTACCTGGTCATATGACACCACGATCGGAGTGGCGATGTTGATCGGTAGGTTCTT
CCTGATCATTCCGGTGCTGGCGATCGCCGGCTCCCTGGCACGTAAAGGCACGACGCCGGTTACCGCCGCCACCTTCCCGA
CGCACAAGCCGCTCTTTGTTGGCCTGGTCATTGGGGTCGTACTGATCGTCGGCGGCCTGACGTTCTTCCCCGCCCTGGCG
CTGGGGCCGATCGTCGAGCAGTTATCGACCCAGTGA

Upstream 100 bases:

>100_bases
GAATGGCGATGACTACGGTCGACAACATCGTCGGGTTGGTGATCGCGGTGGCGCTAATGGCGTTCCTATTCGCGGCGCTG
CTGTTTCCGGAGAAGTTCTG

Downstream 100 bases:

>100_bases
TGATCGCACGCATGGAGACCTCCGCAACCGCCGCGGCAGCGACGTCGGCACCCCGGCTCCGGCTGGCCAAGCGCTCGCTG
TTCGATCCGATGATTGTGCG

Product: potassium-transporting ATPase subunit A

Products: NA

Alternate protein names: ATP phosphohydrolase [potassium-transporting] A chain; Potassium-binding and translocating subunit A; Potassium-translocating ATPase A chain

Number of amino acids: Translated: 571; Mature: 570

Protein sequence:

>571_residues
MSGTSWLQFAALIAVLLLTAPALGGYLAKIYGDEAKKPGDRVFGPIERVIYQVCRVDPGSEQRWSTYALSVLAFSVMSFL
LLYGIARFQGVLPFNPTDKPAVTDHVAFNAAVSFMTNTNWQSYSGEATMSHFTQMTGLAVQNFVSASAGMCVLAALIRGL
ARKRASTLGNFWVDLARTVLRIMFPLSFVVAILLVSQGVIQNLHGFIVANTLEGAPQLIPGGPVASQVAIKQLGTNGGGF
FNVNSAHPFENYTPIGNFVENWAILIIPFALCFAFGKMVHDRRQGWAVLAIMGIIWIGMSVAAMSFEAKGNPRLDALGVT
QQTTVDQSGGNLEGKEVRFGVGASGLWAASTTGTSNGSVNSMHDSYTPLGGMVPLAHMMLGEVSPGGTGVGLNGLLVMAI
LAVFIAGLMVGRTPEYLGKKIQATEMKLVTLYILAMPIALLSFAAASVLISSALASRNNPGPHGLSEILYAYTSGANNNG
SAFAGLTASTWSYDTTIGVAMLIGRFFLIIPVLAIAGSLARKGTTPVTAATFPTHKPLFVGLVIGVVLIVGGLTFFPALA
LGPIVEQLSTQ

Sequences:

>Translated_571_residues
MSGTSWLQFAALIAVLLLTAPALGGYLAKIYGDEAKKPGDRVFGPIERVIYQVCRVDPGSEQRWSTYALSVLAFSVMSFL
LLYGIARFQGVLPFNPTDKPAVTDHVAFNAAVSFMTNTNWQSYSGEATMSHFTQMTGLAVQNFVSASAGMCVLAALIRGL
ARKRASTLGNFWVDLARTVLRIMFPLSFVVAILLVSQGVIQNLHGFIVANTLEGAPQLIPGGPVASQVAIKQLGTNGGGF
FNVNSAHPFENYTPIGNFVENWAILIIPFALCFAFGKMVHDRRQGWAVLAIMGIIWIGMSVAAMSFEAKGNPRLDALGVT
QQTTVDQSGGNLEGKEVRFGVGASGLWAASTTGTSNGSVNSMHDSYTPLGGMVPLAHMMLGEVSPGGTGVGLNGLLVMAI
LAVFIAGLMVGRTPEYLGKKIQATEMKLVTLYILAMPIALLSFAAASVLISSALASRNNPGPHGLSEILYAYTSGANNNG
SAFAGLTASTWSYDTTIGVAMLIGRFFLIIPVLAIAGSLARKGTTPVTAATFPTHKPLFVGLVIGVVLIVGGLTFFPALA
LGPIVEQLSTQ
>Mature_570_residues
SGTSWLQFAALIAVLLLTAPALGGYLAKIYGDEAKKPGDRVFGPIERVIYQVCRVDPGSEQRWSTYALSVLAFSVMSFLL
LYGIARFQGVLPFNPTDKPAVTDHVAFNAAVSFMTNTNWQSYSGEATMSHFTQMTGLAVQNFVSASAGMCVLAALIRGLA
RKRASTLGNFWVDLARTVLRIMFPLSFVVAILLVSQGVIQNLHGFIVANTLEGAPQLIPGGPVASQVAIKQLGTNGGGFF
NVNSAHPFENYTPIGNFVENWAILIIPFALCFAFGKMVHDRRQGWAVLAIMGIIWIGMSVAAMSFEAKGNPRLDALGVTQ
QTTVDQSGGNLEGKEVRFGVGASGLWAASTTGTSNGSVNSMHDSYTPLGGMVPLAHMMLGEVSPGGTGVGLNGLLVMAIL
AVFIAGLMVGRTPEYLGKKIQATEMKLVTLYILAMPIALLSFAAASVLISSALASRNNPGPHGLSEILYAYTSGANNNGS
AFAGLTASTWSYDTTIGVAMLIGRFFLIIPVLAIAGSLARKGTTPVTAATFPTHKPLFVGLVIGVVLIVGGLTFFPALAL
GPIVEQLSTQ

Specific function: One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions

COG id: COG2060

COG function: function code P; K+-transporting ATPase, A chain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdpA family

Homologues:

Organism=Escherichia coli, GI1786915, Length=569, Percent_Identity=50.2636203866432, Blast_Score=532, Evalue=1e-152,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATKA_MYCBO (P65210)

Other databases:

- EMBL:   BX248337
- RefSeq:   NP_854714.1
- ProteinModelPortal:   P65210
- EnsemblBacteria:   EBMYCT00000015805
- GeneID:   1091664
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb1058
- GeneTree:   EBGT00050000017659
- HOGENOM:   HBG291815
- OMA:   GAIQNFH
- ProtClustDB:   PRK05482
- BioCyc:   MBOV233413:MB1058-MONOMER
- BRENDA:   3.6.3.12
- HAMAP:   MF_00275
- InterPro:   IPR004623
- PIRSF:   PIRSF001294
- TIGRFAMs:   TIGR00680

Pfam domain/function: PF03814 KdpA

EC number: =3.6.3.12

Molecular weight: Translated: 60164; Mature: 60033

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x14bc8fcc)-; HASH(0x14afcf80)-; HASH(0x14f329ac)-; HASH(0x1273c434)-; HASH(0x133ed260)-; HASH(0x1507c330)-; HASH(0x151b208c)-; HASH(0x14a0aa28)-; HASH(0x15011988)-; HASH(0x14fc11ac)-; HASH(0x14097a30)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure 
SGTSWLQFAALIAVLLLTAPALGGYLAKIYGDEAKKPGDRVFGPIERVIYQVCRVDPGS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCC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HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972