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The map label for this gene is arcA

Identifier: 121636930

GI number: 121636930

Start: 1147674

End: 1148882

Strand: Direct

Name: arcA

Synonym: BCG_1058

Alternate gene names: 121636930

Gene position: 1147674-1148882 (Clockwise)

Preceding gene: 121636928

Following gene: 121636932

Centisome position: 26.24

GC content: 65.67

Gene sequence:

>1209_bases
GTGGGTGTCGAATTGGGGTCAAATTCCGAGGTCGGCGCGCTAAGAGTGGTCATCCTGCACCGCCCGGGGGCCGAACTGCG
CCGGCTCACACCGCGCAACACCGACCAGCTGCTGTTCGACGGCCTGCCCTGGGTATCCCGCGCGCAGGACGAGCACGACG
AATTCGCCGAGCTGCTGGCTTCCCGCGGTGCGGAAGTGCTGTTGCTGTCGGACCTGTTGACTGAGGCACTACATCACAGC
GGGGCCGCCCGCATGCAGGGGATCGCCGCTGCCGTCGACGCACCGCGGCTGGGACTGCCGCTGGCGCAAGAGCTTTCGGC
CTACCTGCGTAGTCTCGACCCAGGCAGGTTGGCGCATGTGCTGACGGCCGGCATGACCTTCAACGAGCTCCCGTCGGACA
CGCGGACCGACGTGTCGTTGGTGTTGCGTATGCACCATGGCGGAGACTTCGTCATTGAGCCGTTGCCGAACCTGGTGTTC
ACCCGCGACTCGTCGATATGGATCGGGCCGCGGGTGGTGATCCCGTCGCTGGCATTACGGGCACGGGTGCGCGAAGCGTC
GCTGACCGACCTCATCTATGCTCATCACCCGCGGTTCACCGGTGTGCGGCGTGCCTATGAATCGCGCACCGCTCCGGTCG
AGGGTGGCGACGTGTTGTTGCTCGCCCCGGGTGTGGTCGCTGTCGGAGTGGGCGAGCGGACTACACCAGCAGGCGCGGAA
GCATTGGCGCGCAGCCTTTTTGACGATGATCTTGCGCATACCGTGCTCGCCGTGCCGATCGCTCAGCAGCGCGCGCAAAT
GCATCTGGACACGGTGTGCACGATGGTCGACACCGATACGATGGTGATGTACGCCAACGTTGTCGACACGCTCGAGGCGT
TCACGATCCAGCGCACACCCGACGGCGTGACCATCGGCGATGCGGCCCCGTTCGCGGAGGCGGCTGCCAAGGCGATGGGA
ATCGACAAGCTGCGGGTAATTCATACCGGAATGGACCCCGTCGTCGCTGAACGCGAACAGTGGGACGACGGCAACAACAC
GTTGGCGTTGGCGCCCGGTGTCGTTGTCGCCTACGAGCGCAACGTACAGACCAACGCCCGCCTGCAGGACGCGGGCATCG
AAGTGCTTACCATCGCCGGCTCCGAATTGGGTACCGGCCGTGGCGGGCCCCGCTGCATGTCCTGTCCGGCCGCCCGCGAT
CCGCTTTAG

Upstream 100 bases:

>100_bases
GCTCGTTGTGCTCGAAGAGCGCGCCTTGAACCGCGATCGCCACGCCGCCAAGCTTATCGCACATTCGTTCGATGGCGCCG
CCCCGGCTACGGTTTGACCT

Downstream 100 bases:

>100_bases
GAGTGGCGATTTCGGCGCCTGGCGGCGCCGCAGATCACCGCCAGCTGGGCAGCCAGATCTCCAGGTTCCAGGTCTGTTGT
GAGATTGGCAGACCGGTGAG

Product: arginine deiminase

Products: NA

Alternate protein names: ADI; Arginine dihydrolase; AD

Number of amino acids: Translated: 402; Mature: 401

Protein sequence:

>402_residues
MGVELGSNSEVGALRVVILHRPGAELRRLTPRNTDQLLFDGLPWVSRAQDEHDEFAELLASRGAEVLLLSDLLTEALHHS
GAARMQGIAAAVDAPRLGLPLAQELSAYLRSLDPGRLAHVLTAGMTFNELPSDTRTDVSLVLRMHHGGDFVIEPLPNLVF
TRDSSIWIGPRVVIPSLALRARVREASLTDLIYAHHPRFTGVRRAYESRTAPVEGGDVLLLAPGVVAVGVGERTTPAGAE
ALARSLFDDDLAHTVLAVPIAQQRAQMHLDTVCTMVDTDTMVMYANVVDTLEAFTIQRTPDGVTIGDAAPFAEAAAKAMG
IDKLRVIHTGMDPVVAEREQWDDGNNTLALAPGVVVAYERNVQTNARLQDAGIEVLTIAGSELGTGRGGPRCMSCPAARD
PL

Sequences:

>Translated_402_residues
MGVELGSNSEVGALRVVILHRPGAELRRLTPRNTDQLLFDGLPWVSRAQDEHDEFAELLASRGAEVLLLSDLLTEALHHS
GAARMQGIAAAVDAPRLGLPLAQELSAYLRSLDPGRLAHVLTAGMTFNELPSDTRTDVSLVLRMHHGGDFVIEPLPNLVF
TRDSSIWIGPRVVIPSLALRARVREASLTDLIYAHHPRFTGVRRAYESRTAPVEGGDVLLLAPGVVAVGVGERTTPAGAE
ALARSLFDDDLAHTVLAVPIAQQRAQMHLDTVCTMVDTDTMVMYANVVDTLEAFTIQRTPDGVTIGDAAPFAEAAAKAMG
IDKLRVIHTGMDPVVAEREQWDDGNNTLALAPGVVVAYERNVQTNARLQDAGIEVLTIAGSELGTGRGGPRCMSCPAARD
PL
>Mature_401_residues
GVELGSNSEVGALRVVILHRPGAELRRLTPRNTDQLLFDGLPWVSRAQDEHDEFAELLASRGAEVLLLSDLLTEALHHSG
AARMQGIAAAVDAPRLGLPLAQELSAYLRSLDPGRLAHVLTAGMTFNELPSDTRTDVSLVLRMHHGGDFVIEPLPNLVFT
RDSSIWIGPRVVIPSLALRARVREASLTDLIYAHHPRFTGVRRAYESRTAPVEGGDVLLLAPGVVAVGVGERTTPAGAEA
LARSLFDDDLAHTVLAVPIAQQRAQMHLDTVCTMVDTDTMVMYANVVDTLEAFTIQRTPDGVTIGDAAPFAEAAAKAMGI
DKLRVIHTGMDPVVAEREQWDDGNNTLALAPGVVVAYERNVQTNARLQDAGIEVLTIAGSELGTGRGGPRCMSCPAARDP
L

Specific function: Unknown

COG id: COG2235

COG function: function code E; Arginine deiminase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginine deiminase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARCA_MYCBO (P63552)

Other databases:

- EMBL:   BX248337
- RefSeq:   NP_854685.1
- ProteinModelPortal:   P63552
- EnsemblBacteria:   EBMYCT00000015157
- GeneID:   1093345
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb1028
- GeneTree:   EBGT00050000017417
- HOGENOM:   HBG298398
- OMA:   EEHDQFA
- ProtClustDB:   PRK01388
- BioCyc:   MBOV233413:MB1028-MONOMER
- BRENDA:   3.5.3.6
- GO:   GO:0005737
- HAMAP:   MF_00242
- InterPro:   IPR003198
- InterPro:   IPR003876
- PIRSF:   PIRSF006356
- PRINTS:   PR01466
- TIGRFAMs:   TIGR01078

Pfam domain/function: PF02274 Amidinotransf

EC number: =3.5.3.6

Molecular weight: Translated: 43090; Mature: 42959

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: ACT_SITE 392-392

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVELGSNSEVGALRVVILHRPGAELRRLTPRNTDQLLFDGLPWVSRAQDEHDEFAELLA
CCCCCCCCCCCCEEEEEEEECCCHHHHHCCCCCCCHHHCCCCCCHHHCCCHHHHHHHHHH
SRGAEVLLLSDLLTEALHHSGAARMQGIAAAVDAPRLGLPLAQELSAYLRSLDPGRLAHV
HCCCCEEEHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHH
LTAGMTFNELPSDTRTDVSLVLRMHHGGDFVIEPLPNLVFTRDSSIWIGPRVVIPSLALR
HHCCCCHHCCCCCCCCCEEEEEEEECCCCEEEECCCCEEEECCCCEEECCHHHHHHHHHH
ARVREASLTDLIYAHHPRFTGVRRAYESRTAPVEGGDVLLLAPGVVAVGVGERTTPAGAE
HHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCEEEECCCEEEECCCCCCCCCHHH
ALARSLFDDDLAHTVLAVPIAQQRAQMHLDTVCTMVDTDTMVMYANVVDTLEAFTIQRTP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHEEEEECC
DGVTIGDAAPFAEAAAKAMGIDKLRVIHTGMDPVVAEREQWDDGNNTLALAPGVVVAYER
CCEEECCCCHHHHHHHHHHCCCCEEEEECCCCCHHHHHHCCCCCCCEEEECCCEEEEEEC
NVQTNARLQDAGIEVLTIAGSELGTGRGGPRCMSCPAARDPL
CCCCCCEEECCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GVELGSNSEVGALRVVILHRPGAELRRLTPRNTDQLLFDGLPWVSRAQDEHDEFAELLA
CCCCCCCCCCCEEEEEEEECCCHHHHHCCCCCCCHHHCCCCCCHHHCCCHHHHHHHHHH
SRGAEVLLLSDLLTEALHHSGAARMQGIAAAVDAPRLGLPLAQELSAYLRSLDPGRLAHV
HCCCCEEEHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHH
LTAGMTFNELPSDTRTDVSLVLRMHHGGDFVIEPLPNLVFTRDSSIWIGPRVVIPSLALR
HHCCCCHHCCCCCCCCCEEEEEEEECCCCEEEECCCCEEEECCCCEEECCHHHHHHHHHH
ARVREASLTDLIYAHHPRFTGVRRAYESRTAPVEGGDVLLLAPGVVAVGVGERTTPAGAE
HHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCEEEECCCEEEECCCCCCCCCHHH
ALARSLFDDDLAHTVLAVPIAQQRAQMHLDTVCTMVDTDTMVMYANVVDTLEAFTIQRTP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHEEEEECC
DGVTIGDAAPFAEAAAKAMGIDKLRVIHTGMDPVVAEREQWDDGNNTLALAPGVVVAYER
CCEEECCCCHHHHHHHHHHCCCCEEEEECCCCCHHHHHHCCCCCCCEEEECCCEEEEEEC
NVQTNARLQDAGIEVLTIAGSELGTGRGGPRCMSCPAARDPL
CCCCCCEEECCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972