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The map label for this gene is csoR

Identifier: 121636893

GI number: 121636893

Start: 1108451

End: 1108810

Strand: Direct

Name: csoR

Synonym: BCG_1021

Alternate gene names: 121636893

Gene position: 1108451-1108810 (Clockwise)

Preceding gene: 121636887

Following gene: 121636894

Centisome position: 25.34

GC content: 62.78

Gene sequence:

>360_bases
ATGAGCAAGGAATTGACCGCAAAGAAGCGCGCGGCGCTGAACCGGCTGAAGACGGTTCGGGGCCATCTTGACGGAATCGT
TCGGATGCTGGAGTCCGACGCCTACTGCGTGGACGTGATGAAGCAGATTTCAGCGGTTCAGTCCTCGCTGGAGCGGGCCA
ACCGGGTGATGCTGCACAACCACTTGGAGACGTGCTTTTCCACGGCGGTGCTGGATGGTCATGGGCAAGCGGCCATCGAA
GAGCTCATTGATGCCGTCAAATTCACGCCGGCGCTGACCGGTCCACACGCGCGGCTCGGCGGTGCCGCGGTCGGCGAGTC
GGCCACCGAGGAGCCGATGCCGGATGCCAGCAACATGTGA

Upstream 100 bases:

>100_bases
GGTGTTGGCGAAACTGCAAATGTTGCCAGGTTCGACTCCTTGGTAGCCCACCCCCAGTGGGGTGGGATACCATGAACGGG
TGAGGGATTAGGGGCAAGCC

Downstream 100 bases:

>100_bases
CGAGCGCCGGACTCCGGTGTTTCTCGGGACAACGACATACGAAAGGAGCATCCGCGATGGTGTGGCATGGATTCCTAGCG
AAGGCGGTACCCACCGTGGT

Product: hypothetical protein

Products: NA

Alternate protein names: Copper-sensitive operon repressor

Number of amino acids: Translated: 119; Mature: 118

Protein sequence:

>119_residues
MSKELTAKKRAALNRLKTVRGHLDGIVRMLESDAYCVDVMKQISAVQSSLERANRVMLHNHLETCFSTAVLDGHGQAAIE
ELIDAVKFTPALTGPHARLGGAAVGESATEEPMPDASNM

Sequences:

>Translated_119_residues
MSKELTAKKRAALNRLKTVRGHLDGIVRMLESDAYCVDVMKQISAVQSSLERANRVMLHNHLETCFSTAVLDGHGQAAIE
ELIDAVKFTPALTGPHARLGGAAVGESATEEPMPDASNM
>Mature_118_residues
SKELTAKKRAALNRLKTVRGHLDGIVRMLESDAYCVDVMKQISAVQSSLERANRVMLHNHLETCFSTAVLDGHGQAAIEE
LIDAVKFTPALTGPHARLGGAAVGESATEEPMPDASNM

Specific function: Copper-sensitive repressor that has a key role in copper homeostasis. It is part of the cso operon involved in the cellular response to increasing concentrations of copper inside the bacterium, which can be highly toxic. In the presence of copper, CsoR fu

COG id: COG1937

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CsoR family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CSOR_MYCBO (Q7U0Y5)

Other databases:

- EMBL:   BX248337
- RefSeq:   NP_854649.1
- ProteinModelPortal:   Q7U0Y5
- SMR:   Q7U0Y5
- EnsemblBacteria:   EBMYCT00000016638
- GeneID:   1093077
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb0992
- GeneTree:   EBGT00050000017289
- HOGENOM:   HBG569719
- OMA:   CIDVANQ
- ProtClustDB:   CLSK790861
- BioCyc:   MBOV233413:MB0992-MONOMER
- GO:   GO:0005737
- GO:   GO:0006350
- InterPro:   IPR003735

Pfam domain/function: PF02583 DUF156

EC number: NA

Molecular weight: Translated: 12800; Mature: 12669

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKELTAKKRAALNRLKTVRGHLDGIVRMLESDAYCVDVMKQISAVQSSLERANRVMLHN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLETCFSTAVLDGHGQAAIEELIDAVKFTPALTGPHARLGGAAVGESATEEPMPDASNM
HHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHCCHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SKELTAKKRAALNRLKTVRGHLDGIVRMLESDAYCVDVMKQISAVQSSLERANRVMLHN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLETCFSTAVLDGHGQAAIEELIDAVKFTPALTGPHARLGGAAVGESATEEPMPDASNM
HHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHCCHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972