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The map label for this gene is 121636816

Identifier: 121636816

GI number: 121636816

Start: 1025775

End: 1026752

Strand: Reverse

Name: 121636816

Synonym: BCG_0945c

Alternate gene names: NA

Gene position: 1026752-1025775 (Counterclockwise)

Preceding gene: 121636820

Following gene: 121636814

Centisome position: 23.47

GC content: 60.63

Gene sequence:

>978_bases
ATGCGGACCGAGGACGATAGCTGGGATGTCACCACGAGTGTTGGTTCGACAGGACTATTGGTAGCCGCCGCAAGAGCATT
GGAGACGCAGAAGGCCGATCCGCTGGCCATCGATCCCTATGCCGAGGTTTTCTGCCGTGCCGCAGGTGGTGAATGGGCCG
ACGTATTGGACGGCAAGCTGCCCGATCACTATCTGACAACCGGGGACTTCGGTGAGCATTTCGTCAACTTCCAAGGTGCC
CGCACCAGGTATTTCGACGAGTATTTCTCCCGGGCAACGGCCGCCGGCATGAAGCAGGTGGTCATCTTGGCTGCAGGATT
GGATTCCCGTGCATTCCGATTGCAATGGCCAATCGGGACAACAATCTTCGAGTTGGATCGACCTCAGGTCCTCGACTTCA
AGAACGCGGTGCTCGCCGACTATCACATACGGCCGCGAGCCCAACGTCGGTCGGTTGCTGTCGATCTGCGCGATGAGTGG
CAGATAGCCTTGTGTAACAACGGATTTGATGCCAACCGGCCGTCGGCTTGGATCGCCGAGGGCCTGCTGGTCTATCTCTC
GGCCGAGGCCCAGCAGCGCCTGTTTATCGGCATCGACACCTTGGCTAGCCCCGGTAGCCACGTTGCTGTCGAGGAAGCAA
CTCCACTGGACCCTTGCGAATTCGCAGCGAAGCTCGAACGAGAACGCGCCGCGAACGCCCAAGGCGACCCGCGCAGGTTC
TTTCAAATGGTCTACAACGAGCGGTGGGCGCGGGCCACGGAATGGTTCGATGAGCGAGGCTGGCGCGCGACCGCTACTCC
ATTGGCCGAGTATCTGCGCCGCGTCGGCCGAGCGGTGCCCGAAGCCGATACCGAAGCTGCGCCAATGGTCACCGCTATAA
CCTTTGTCAGCGCCGTCAGAACGGGATTAGTGGCCGATCCCGCGCGAACGTCACCGTCCAGCACCTCGATAGGCTTCAAG
CGCTTTGAGGCCGACTAG

Upstream 100 bases:

>100_bases
GCGTAGAAGTACCAAGTCCACCGCGCAGATATGTGTGCACGGCCGACTGCGCTGGGATACCGACAGCGGTGGGCGGACTG
GAGCAACTAGAGTTCGATGA

Downstream 100 bases:

>100_bases
TTGCGCGCACCGCAGCATAGCGTCGCAGGTCGTATTCTTCGGGATGTAGGTTAGCGAGCATGGCGCGGTGTTTGGCCGGT
GCAAATGGCCAAACCTCAGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MRTEDDSWDVTTSVGSTGLLVAAARALETQKADPLAIDPYAEVFCRAAGGEWADVLDGKLPDHYLTTGDFGEHFVNFQGA
RTRYFDEYFSRATAAGMKQVVILAAGLDSRAFRLQWPIGTTIFELDRPQVLDFKNAVLADYHIRPRAQRRSVAVDLRDEW
QIALCNNGFDANRPSAWIAEGLLVYLSAEAQQRLFIGIDTLASPGSHVAVEEATPLDPCEFAAKLERERAANAQGDPRRF
FQMVYNERWARATEWFDERGWRATATPLAEYLRRVGRAVPEADTEAAPMVTAITFVSAVRTGLVADPARTSPSSTSIGFK
RFEAD

Sequences:

>Translated_325_residues
MRTEDDSWDVTTSVGSTGLLVAAARALETQKADPLAIDPYAEVFCRAAGGEWADVLDGKLPDHYLTTGDFGEHFVNFQGA
RTRYFDEYFSRATAAGMKQVVILAAGLDSRAFRLQWPIGTTIFELDRPQVLDFKNAVLADYHIRPRAQRRSVAVDLRDEW
QIALCNNGFDANRPSAWIAEGLLVYLSAEAQQRLFIGIDTLASPGSHVAVEEATPLDPCEFAAKLERERAANAQGDPRRF
FQMVYNERWARATEWFDERGWRATATPLAEYLRRVGRAVPEADTEAAPMVTAITFVSAVRTGLVADPARTSPSSTSIGFK
RFEAD
>Mature_325_residues
MRTEDDSWDVTTSVGSTGLLVAAARALETQKADPLAIDPYAEVFCRAAGGEWADVLDGKLPDHYLTTGDFGEHFVNFQGA
RTRYFDEYFSRATAAGMKQVVILAAGLDSRAFRLQWPIGTTIFELDRPQVLDFKNAVLADYHIRPRAQRRSVAVDLRDEW
QIALCNNGFDANRPSAWIAEGLLVYLSAEAQQRLFIGIDTLASPGSHVAVEEATPLDPCEFAAKLERERAANAQGDPRRF
FQMVYNERWARATEWFDERGWRATATPLAEYLRRVGRAVPEADTEAAPMVTAITFVSAVRTGLVADPARTSPSSTSIGFK
RFEAD

Specific function: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0677 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y893_MYCTU (P64747)

Other databases:

- EMBL:   BX842574
- EMBL:   AE000516
- PIR:   B70782
- RefSeq:   NP_215408.1
- RefSeq:   NP_335349.1
- ProteinModelPortal:   P64747
- EnsemblBacteria:   EBMYCT00000001720
- EnsemblBacteria:   EBMYCT00000071808
- GeneID:   885477
- GeneID:   926231
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT0917
- KEGG:   mtu:Rv0893c
- TIGR:   MT0917
- TubercuList:   Rv0893c
- GeneTree:   EBGT00050000015698
- HOGENOM:   HBG570783
- OMA:   WIRAGES
- ProtClustDB:   CLSK790400
- InterPro:   IPR011610
- InterPro:   IPR007213
- TIGRFAMs:   TIGR00027

Pfam domain/function: PF04072 LCM

EC number: NA

Molecular weight: Translated: 36074; Mature: 36074

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: BINDING 126-126

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTEDDSWDVTTSVGSTGLLVAAARALETQKADPLAIDPYAEVFCRAAGGEWADVLDGKL
CCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCCCEEECHHHHHHHHHCCCCHHHHHCCCC
PDHYLTTGDFGEHFVNFQGARTRYFDEYFSRATAAGMKQVVILAAGLDSRAFRLQWPIGT
CCCEECCCCHHHHHHCCCCCHHHHHHHHHHHHHHHCHHEEEEEEECCCCCEEEEECCCCC
TIFELDRPQVLDFKNAVLADYHIRPRAQRRSVAVDLRDEWQIALCNNGFDANRPSAWIAE
EEEECCCCCEECCCCCEEECCCCCCCCCCCCEEEEECCCEEEEEECCCCCCCCCHHHHHC
GLLVYLSAEAQQRLFIGIDTLASPGSHVAVEEATPLDPCEFAAKLERERAANAQGDPRRF
CCCEEEECCCCCEEEEEEHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCCHHHH
FQMVYNERWARATEWFDERGWRATATPLAEYLRRVGRAVPEADTEAAPMVTAITFVSAVR
HHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
TGLVADPARTSPSSTSIGFKRFEAD
HCCCCCCCCCCCCCCCCCCEEECCC
>Mature Secondary Structure
MRTEDDSWDVTTSVGSTGLLVAAARALETQKADPLAIDPYAEVFCRAAGGEWADVLDGKL
CCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCCCEEECHHHHHHHHHCCCCHHHHHCCCC
PDHYLTTGDFGEHFVNFQGARTRYFDEYFSRATAAGMKQVVILAAGLDSRAFRLQWPIGT
CCCEECCCCHHHHHHCCCCCHHHHHHHHHHHHHHHCHHEEEEEEECCCCCEEEEECCCCC
TIFELDRPQVLDFKNAVLADYHIRPRAQRRSVAVDLRDEWQIALCNNGFDANRPSAWIAE
EEEECCCCCEECCCCCEEECCCCCCCCCCCCEEEEECCCEEEEEECCCCCCCCCHHHHHC
GLLVYLSAEAQQRLFIGIDTLASPGSHVAVEEATPLDPCEFAAKLERERAANAQGDPRRF
CCCEEEECCCCCEEEEEEHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCCHHHH
FQMVYNERWARATEWFDERGWRATATPLAEYLRRVGRAVPEADTEAAPMVTAITFVSAVR
HHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
TGLVADPARTSPSSTSIGFKRFEAD
HCCCCCCCCCCCCCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036