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The map label for this gene is PE_PGRS11 [H]

Identifier: 121636677

GI number: 121636677

Start: 877942

End: 879696

Strand: Direct

Name: PE_PGRS11 [H]

Synonym: BCG_0805

Alternate gene names: 121636677

Gene position: 877942-879696 (Clockwise)

Preceding gene: 121636673

Following gene: 121636681

Centisome position: 20.07

GC content: 68.49

Gene sequence:

>1755_bases
ATGTCATTTGTGATCGTGGCGCGGGACGCGTTGGCGGCGGCCGCGGCGGATCTAGCGCAGATCGGTTCGGCAGTGAATGC
GGGCAATCTGGCCGCAGCCAATCCGACGACCGCTGTGGCGGCGGCGGCCGCCGACGAGGTATCGGCGGCACTCGCGGCGC
TGTTCGGCGCGCATGCCCGGGAGTATCAGGCGGCGGCGGCGCAGGCAGCGGCGTATCACGAGCAGTTTGTGCACCGATTG
AGCGCGGCAGCGACATCGTATGCGGTTACCGAGGTGACCATCGCGACGTCGCTCCGGGGGGCGCTGGGCTCGGCGCCCGC
GTCCGTTTCCGACGGGTTCCAAGCGTTCGTCTATGGTCCGATTCACGCGACCGGCCAGCAATGGATCAACAGCCCGGTCG
GCGAGGCGCTCGCCCCGATTGTCAATGCGCCGACAAACGTGCTGCTCGGCCGCGATCTGATCGGCAACGGCGTCACCGGG
ACGGCGGCAGCTCCCAACGGTGGCCCCGGCGGTTTGCTATTCGGTGACGGTGGGGCCGGCTATACCGGCGGTAACGGTGG
GAGTGCCGGGTTAATCGGCAACGGGGGTACCGGTGGCGCCGGCTTTGCCGGCGGAGTGGGCGGCATGGGCGGCACCGGCG
GCTGGTTGATGGGCAACGGCGGCATGGGTGGCGCGGGCGGTGTCGGCGGTAACGGCGGCGCCGGGGGCCAGGCGCTGTTG
TTCGGCAACGGCGGCCTGGGCGGAGCCGGCGGGGCTGGCGGGGTCGATGGGGCTATCGGTCGTGGCGGGTGGTTCATCGG
TACCGGCGGCATGGCCACGATCGGTGGTGGCGGCAACGGGCAGTCGATCGTCATCGACTTCGTGCGGCACGGCCAGACGC
CGGGCAACGCCGCAATGTTGATCGACACGGCGGTGCCCGGACCCGGACTCACCGCGCTGGGCCAGCAACAGGCGCAGGCC
ATCGCCAACGCGCTCGCGGCCAAGGGCCCCTATGCCGGGATCTTCGACTCGCAGTTGATCAGAACGCAGCAGACCGCCGC
GCCGTTGGCGAACTTGCTGGGGATGGCCCCGCAGGTATTGCCCGGGCTCAACGAGATCCATGCCGGCATCTTCGAGGACC
TGCCGCAGATCAGCCCCGCGGGCCTGCTGTATCTCGTCGGCCCGATCGCCTGGACGCTCGGATTTCCCATCGTGCCGATG
CTGGCCCCGGGCTCCACCGACGTCAACGGGATCGTCTTCAACCGAGCCTTTACCGGTGCGGTTCAAACGATCTACGACGC
TTCCTTGGCCAATCCGGTCGTGGCCGCAGACGGCAACATCACGTCGGTCGCTTACTCCAGCGCATTCACCATCGGGGTCG
GGACGATGATGAACGTCGACAATCCCCATCCGCTACTGCTGCTCACCCACCCGGTGCCCAACACCGGCGCCGTCGTGGTA
CAGGGCAATCCCGAGGGCGGCTGGACGCTGGTCAGCTGGGACGGGATACCCGTCGGGCCGGCGTCGCTGCCGACCGCGTT
ATTCGTCGACGTGCGCGAGCTGATCACGGCGCCGCAATATGCGGCCTACGACATTTGGGAGTCCCTGTTCACCGGCGATC
CGGCGGCGGTCATCAACGCGGTGCGAGACGGTGCCGATGAGGTCGGCGCGGCTGTGGTCCAGTTCCCACATGCGGTGGCT
GACGACGTGATCGACGCTACGGGCCACCCCTATCTAAGCGGCCTGCCGATCGGTCTGCCCAGCCTGATCCCATGA

Upstream 100 bases:

>100_bases
GGAGACGCTTGGATGCTCGTTGCATTTTGGCCGATACCCGCATCTGTTCCGGCGCTGCGCTCCATCATGGCTAGTACGCG
ACAACACCCGGGGGTAAGCG

Downstream 100 bases:

>100_bases
CCGCGAGCGACCAATAGGTCCCCACATGGCCCGGAGGCCGCTGCCAGCATTGACCCGACGATGCCGGCCCGCAGGCTTCC
CCGATCGTGCGGAACCTGCT

Product: PE-PGRS family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 584; Mature: 583

Protein sequence:

>584_residues
MSFVIVARDALAAAAADLAQIGSAVNAGNLAAANPTTAVAAAAADEVSAALAALFGAHAREYQAAAAQAAAYHEQFVHRL
SAAATSYAVTEVTIATSLRGALGSAPASVSDGFQAFVYGPIHATGQQWINSPVGEALAPIVNAPTNVLLGRDLIGNGVTG
TAAAPNGGPGGLLFGDGGAGYTGGNGGSAGLIGNGGTGGAGFAGGVGGMGGTGGWLMGNGGMGGAGGVGGNGGAGGQALL
FGNGGLGGAGGAGGVDGAIGRGGWFIGTGGMATIGGGGNGQSIVIDFVRHGQTPGNAAMLIDTAVPGPGLTALGQQQAQA
IANALAAKGPYAGIFDSQLIRTQQTAAPLANLLGMAPQVLPGLNEIHAGIFEDLPQISPAGLLYLVGPIAWTLGFPIVPM
LAPGSTDVNGIVFNRAFTGAVQTIYDASLANPVVAADGNITSVAYSSAFTIGVGTMMNVDNPHPLLLLTHPVPNTGAVVV
QGNPEGGWTLVSWDGIPVGPASLPTALFVDVRELITAPQYAAYDIWESLFTGDPAAVINAVRDGADEVGAAVVQFPHAVA
DDVIDATGHPYLSGLPIGLPSLIP

Sequences:

>Translated_584_residues
MSFVIVARDALAAAAADLAQIGSAVNAGNLAAANPTTAVAAAAADEVSAALAALFGAHAREYQAAAAQAAAYHEQFVHRL
SAAATSYAVTEVTIATSLRGALGSAPASVSDGFQAFVYGPIHATGQQWINSPVGEALAPIVNAPTNVLLGRDLIGNGVTG
TAAAPNGGPGGLLFGDGGAGYTGGNGGSAGLIGNGGTGGAGFAGGVGGMGGTGGWLMGNGGMGGAGGVGGNGGAGGQALL
FGNGGLGGAGGAGGVDGAIGRGGWFIGTGGMATIGGGGNGQSIVIDFVRHGQTPGNAAMLIDTAVPGPGLTALGQQQAQA
IANALAAKGPYAGIFDSQLIRTQQTAAPLANLLGMAPQVLPGLNEIHAGIFEDLPQISPAGLLYLVGPIAWTLGFPIVPM
LAPGSTDVNGIVFNRAFTGAVQTIYDASLANPVVAADGNITSVAYSSAFTIGVGTMMNVDNPHPLLLLTHPVPNTGAVVV
QGNPEGGWTLVSWDGIPVGPASLPTALFVDVRELITAPQYAAYDIWESLFTGDPAAVINAVRDGADEVGAAVVQFPHAVA
DDVIDATGHPYLSGLPIGLPSLIP
>Mature_583_residues
SFVIVARDALAAAAADLAQIGSAVNAGNLAAANPTTAVAAAAADEVSAALAALFGAHAREYQAAAAQAAAYHEQFVHRLS
AAATSYAVTEVTIATSLRGALGSAPASVSDGFQAFVYGPIHATGQQWINSPVGEALAPIVNAPTNVLLGRDLIGNGVTGT
AAAPNGGPGGLLFGDGGAGYTGGNGGSAGLIGNGGTGGAGFAGGVGGMGGTGGWLMGNGGMGGAGGVGGNGGAGGQALLF
GNGGLGGAGGAGGVDGAIGRGGWFIGTGGMATIGGGGNGQSIVIDFVRHGQTPGNAAMLIDTAVPGPGLTALGQQQAQAI
ANALAAKGPYAGIFDSQLIRTQQTAAPLANLLGMAPQVLPGLNEIHAGIFEDLPQISPAGLLYLVGPIAWTLGFPIVPML
APGSTDVNGIVFNRAFTGAVQTIYDASLANPVVAADGNITSVAYSSAFTIGVGTMMNVDNPHPLLLLTHPVPNTGAVVVQ
GNPEGGWTLVSWDGIPVGPASLPTALFVDVRELITAPQYAAYDIWESLFTGDPAAVINAVRDGADEVGAAVVQFPHAVAD
DVIDATGHPYLSGLPIGLPSLIP

Specific function: Unknown

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PE family. PGRS subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000084 [H]

Pfam domain/function: PF00934 PE [H]

EC number: NA

Molecular weight: Translated: 56946; Mature: 56814

Theoretical pI: Translated: 4.20; Mature: 4.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFVIVARDALAAAAADLAQIGSAVNAGNLAAANPTTAVAAAAADEVSAALAALFGAHAR
CEEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EYQAAAAQAAAYHEQFVHRLSAAATSYAVTEVTIATSLRGALGSAPASVSDGFQAFVYGP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHCCCCCCCCCCCEEEEEEC
IHATGQQWINSPVGEALAPIVNAPTNVLLGRDLIGNGVTGTAAAPNGGPGGLLFGDGGAG
CCCCHHHHHCCHHHHHHHHHHCCCCCEEECCHHHCCCCCCCCCCCCCCCCEEEECCCCCC
YTGGNGGSAGLIGNGGTGGAGFAGGVGGMGGTGGWLMGNGGMGGAGGVGGNGGAGGQALL
CCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCEEEE
FGNGGLGGAGGAGGVDGAIGRGGWFIGTGGMATIGGGGNGQSIVIDFVRHGQTPGNAAML
EECCCCCCCCCCCCCCCCCCCCCEEEECCCEEEECCCCCCCEEEEEHHHCCCCCCCEEEE
IDTAVPGPGLTALGQQQAQAIANALAAKGPYAGIFDSQLIRTQQTAAPLANLLGMAPQVL
EEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHH
PGLNEIHAGIFEDLPQISPAGLLYLVGPIAWTLGFPIVPMLAPGSTDVNGIVFNRAFTGA
CCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCEEEEECHHHHH
VQTIYDASLANPVVAADGNITSVAYSSAFTIGVGTMMNVDNPHPLLLLTHPVPNTGAVVV
HHHHHHHHHCCCEEECCCCEEEEEECCEEEEECCEEEECCCCCCEEEEECCCCCCCEEEE
QGNPEGGWTLVSWDGIPVGPASLPTALFVDVRELITAPQYAAYDIWESLFTGDPAAVINA
EECCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHH
VRDGADEVGAAVVQFPHAVADDVIDATGHPYLSGLPIGLPSLIP
HHCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SFVIVARDALAAAAADLAQIGSAVNAGNLAAANPTTAVAAAAADEVSAALAALFGAHAR
EEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EYQAAAAQAAAYHEQFVHRLSAAATSYAVTEVTIATSLRGALGSAPASVSDGFQAFVYGP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHCCCCCCCCCCCEEEEEEC
IHATGQQWINSPVGEALAPIVNAPTNVLLGRDLIGNGVTGTAAAPNGGPGGLLFGDGGAG
CCCCHHHHHCCHHHHHHHHHHCCCCCEEECCHHHCCCCCCCCCCCCCCCCEEEECCCCCC
YTGGNGGSAGLIGNGGTGGAGFAGGVGGMGGTGGWLMGNGGMGGAGGVGGNGGAGGQALL
CCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCEEEE
FGNGGLGGAGGAGGVDGAIGRGGWFIGTGGMATIGGGGNGQSIVIDFVRHGQTPGNAAML
EECCCCCCCCCCCCCCCCCCCCCEEEECCCEEEECCCCCCCEEEEEHHHCCCCCCCEEEE
IDTAVPGPGLTALGQQQAQAIANALAAKGPYAGIFDSQLIRTQQTAAPLANLLGMAPQVL
EEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHH
PGLNEIHAGIFEDLPQISPAGLLYLVGPIAWTLGFPIVPMLAPGSTDVNGIVFNRAFTGA
CCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCEEEEECHHHHH
VQTIYDASLANPVVAADGNITSVAYSSAFTIGVGTMMNVDNPHPLLLLTHPVPNTGAVVV
HHHHHHHHHCCCEEECCCCEEEEEECCEEEEECCEEEECCCCCCEEEEECCCCCCCEEEE
QGNPEGGWTLVSWDGIPVGPASLPTALFVDVRELITAPQYAAYDIWESLFTGDPAAVINA
EECCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHH
VRDGADEVGAAVVQFPHAVADDVIDATGHPYLSGLPIGLPSLIP
HHCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]