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The map label for this gene is 121636558

Identifier: 121636558

GI number: 121636558

Start: 763701

End: 764201

Strand: Direct

Name: 121636558

Synonym: BCG_0686

Alternate gene names: NA

Gene position: 763701-764201 (Clockwise)

Preceding gene: 121636557

Following gene: 121636559

Centisome position: 17.46

GC content: 60.48

Gene sequence:

>501_bases
ATGGCGCTCAAGACCGATATCCGCGGGATGATTTGGCGGTACCCGGACTACTTCATCGTGGGCCGTGAGCAATGCCGCGA
GTTTGCCCGAGCTGTCAAGTGCGACCACCCGGCCTTTTTCAGCGAGGAAGCGGCCGCCGACCTCGGTTACGACGCGCTGG
TTGCTCCGCTGACCTTCGTGACGATCCTCGCCAAATATGTGCAACTGGACTTCTTCCGCCACGTCGACGTGGGCATGGAG
ACGATGCAGATCGTTCAGGTCGACCAGCGGTTCGTGTTCCACAAACCCGTGCTCGCCGGGGACAAGTTGTGGGCTCGGAT
GGACATCCATTCGGTGGACGAGCGGTTCGGCGCAGACATCGTCGTTACCAGAAACCTCTGCACCAACGACGACGGTGAGC
TGGTCATGGAGGCCTACACCACGCTGATGGGCCAGCAGGGTGATGGTTCCGCCAGACTCAAATGGGACAAGGAATCCGGG
CAGGTCATCAGGACCGCGTAA

Upstream 100 bases:

>100_bases
TGATCCTGAGAGCAAGTCGGTGACCATCGCACTCACCGCTACTACCGGCGGCAAGAAGATTTTCGGGCGGGCCATCGCCT
CGGCGAAGTTAGCGTAGTTT

Downstream 100 bases:

>100_bases
TTAGCAACTGGCCGCTGCGGCCATGTACACTCGGACCTCGGGGTTTTCCCAACATCGGCGCGCTTTCCGTGAGTTCAACG
AGCGGAGTGTCGTCTCCACT

Product: (3R)-hydroxyacyl-ACP dehydratase subunit HadC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 166; Mature: 165

Protein sequence:

>166_residues
MALKTDIRGMIWRYPDYFIVGREQCREFARAVKCDHPAFFSEEAAADLGYDALVAPLTFVTILAKYVQLDFFRHVDVGME
TMQIVQVDQRFVFHKPVLAGDKLWARMDIHSVDERFGADIVVTRNLCTNDDGELVMEAYTTLMGQQGDGSARLKWDKESG
QVIRTA

Sequences:

>Translated_166_residues
MALKTDIRGMIWRYPDYFIVGREQCREFARAVKCDHPAFFSEEAAADLGYDALVAPLTFVTILAKYVQLDFFRHVDVGME
TMQIVQVDQRFVFHKPVLAGDKLWARMDIHSVDERFGADIVVTRNLCTNDDGELVMEAYTTLMGQQGDGSARLKWDKESG
QVIRTA
>Mature_165_residues
ALKTDIRGMIWRYPDYFIVGREQCREFARAVKCDHPAFFSEEAAADLGYDALVAPLTFVTILAKYVQLDFFRHVDVGMET
MQIVQVDQRFVFHKPVLAGDKLWARMDIHSVDERFGADIVVTRNLCTNDDGELVMEAYTTLMGQQGDGSARLKWDKESGQ
VIRTA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0336 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y637_MYCTU (P96928)

Other databases:

- EMBL:   BX842574
- EMBL:   AE000516
- PIR:   B70613
- RefSeq:   NP_215151.1
- RefSeq:   NP_335077.1
- ProteinModelPortal:   P96928
- DIP:   DIP-46459N
- EnsemblBacteria:   EBMYCT00000001715
- EnsemblBacteria:   EBMYCT00000072033
- GeneID:   888019
- GeneID:   925948
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT0666
- KEGG:   mtu:Rv0637
- TIGR:   MT0666
- TubercuList:   Rv0637
- GeneTree:   EBGT00050000015263
- HOGENOM:   HBG659807
- OMA:   NSISAGW
- ProtClustDB:   PRK13691
- BioCyc:   MetaCyc:RV0637-MONOMER
- HAMAP:   MF_00799
- InterPro:   IPR016709
- PIRSF:   PIRSF018072

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 18930; Mature: 18799

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALKTDIRGMIWRYPDYFIVGREQCREFARAVKCDHPAFFSEEAAADLGYDALVAPLTFV
CCCCCCCCHHEECCCCEEEECHHHHHHHHHHHCCCCCCCCCCHHHHHCCHHHHHHHHHHH
TILAKYVQLDFFRHVDVGMETMQIVQVDQRFVFHKPVLAGDKLWARMDIHSVDERFGADI
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCEEECCHHHHHHHHCCCE
VVTRNLCTNDDGELVMEAYTTLMGQQGDGSARLKWDKESGQVIRTA
EEECCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEECC
>Mature Secondary Structure 
ALKTDIRGMIWRYPDYFIVGREQCREFARAVKCDHPAFFSEEAAADLGYDALVAPLTFV
CCCCCCCHHEECCCCEEEECHHHHHHHHHHHCCCCCCCCCCHHHHHCCHHHHHHHHHHH
TILAKYVQLDFFRHVDVGMETMQIVQVDQRFVFHKPVLAGDKLWARMDIHSVDERFGADI
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCEEECCHHHHHHHHCCCE
VVTRNLCTNDDGELVMEAYTTLMGQQGDGSARLKWDKESGQVIRTA
EEECCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036