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The map label for this gene is PPE11

Identifier: 121636367

GI number: 121636367

Start: 573989

End: 575545

Strand: Direct

Name: PPE11

Synonym: BCG_0492

Alternate gene names: 121636367

Gene position: 573989-575545 (Clockwise)

Preceding gene: 121636366

Following gene: 121636368

Centisome position: 13.12

GC content: 67.76

Gene sequence:

>1557_bases
ATGACGAGCGCACTGATATGGATGGCCTCTCCGCCGGAGGTGCATTCGGCCTTGTTGAGTAGTGGGCCGGGGCCGGGGCC
GGTACTGGCCGCCGCCACAGGGTGGTCGTCACTGGGCCGTGAATACGCCGCGGTTGCTGAGGAACTCGGGGCATTGCTGG
CTGCGGTGCAAGCCGGGGTGTGGCAGGGGCCCAGCGCCGAATCATTTGCTGCCGCGTGCCTGCCGTATCTGTCTTGGTTG
ACGCAGGCCAGCGCCGACTGCGCCGCGGCGGCTGCCCGGCTGGAGGCGGTGACCGCCGCCTACGCCGCGGCTTTGGTGGC
CATGCCCACCCTGGCCGAGTTGGCGGCTAACCACGCGACCCACGGGGCCATGGTGGCGACCAATTTCTTCGGGATCAACA
CCATACCGATCGCGGTCAACGAGGCCGACTACGTGCGGATGTGGCTTCAGGCGGCCACCACGATGGCCACCTATCAAGCG
GTCGCGGACTCGGCGGTGCGCTCGATCCCGGACAGCGTGCCTCCGCCGCGAATTCTGAAATCCAATGCCCAATCCCAACA
CTCGAGCTCGAATAATTCCGGGGGCGCGGACCCGGTGGACGACTTCATTGCAGAGATCTTGAAGATCATCACCGGCGGTC
GCGTGATCTGGGACCCCGAAGCCGGCACTGTCAACGGCCTCCCCTATGACGCTTATACCAACCCCGGCACACTCATGTGG
TGGATTGCCAGAAGTCTGGAACTTCTTCAAGACTTTCAAGAGTTCGCCAAGCTGCTGTTCACCAATCCGGTGAAGGCTTT
TCAGTTCCTTGTCGACCTCATCCTGTTCGACTGGCCTACACACATGCTGCAGCTGGCTACCTGGCTGGCCGAGAACCCGC
AGTTGCTGGTGGCTGCGCTCACCCCAGCCATCTCCGGACTGGGAGCGGTATCGGGGTTGGCCGGGTTGACCGGCCTAGTC
CCTCAGCCCCCCGTCGTGCCCGCGCCGGCACCCGATGCGGTCGTGCCCACCGTGTTGCCACTCGCCGGGACGGCCACGCC
GACTACCGCGCCGGCCAGCGCCCCGGCCGCCGGAGCGGCGCCCGGGCCCCCGGCCGGTACCGCCACTGCCACATCGGCGT
CGGTGCCAACGAGCGCCGGCGGCTTTCCCCCTTACCTCGTGGGCAGCGGTCCAGGCATCGACTTCGACGCGGGGACGCCC
GCCGGTTCCAGGAGAGCGCAGCCCGCCGCGGATAACGTCACGGCCGTGGCGGCAGCGCAGGTGTCGGCCCGTCATCAGGC
ACGTCGGCGCCGACGAGCGGCGGCGAAGGAACGTGGCAACGCCGACGAGTTCGTCGATATGGACTCCGGCCCGGCGATTC
CGCCGTCGGGCGAGCGGGACGCTTGGGCGTCCAATTCGGGCGTGGGCGGGCTGGGGTTTGCCGGCACCGCAAGCAACGAG
ACGGTGGCAGCGCCGGCCGGATTGACCACGCTGGCCGACGATGAGTTCCAGTGTGGCCCACGGATGCCGATGCTGCCGGG
CGCTTGGGACTTGGGAACTTGGGACCGCGGGGACTGA

Upstream 100 bases:

>100_bases
AGACCGCAACTACGGCGCGCGCCGTGGCGGTCGCTAGGTCCGGAATGGATTGTGTGGCCGGTGATGCGTCAGGGGCGACT
TCGTGCCTACGCGGTGAGCT

Downstream 100 bases:

>100_bases
TTACCCTACAACGCAGCGACGTCGCGCATGATGTCGGTGGGTTCGCGCACCGGCGCCCCACAGGTCAGGCAGAACGCGCC
CGGGGAACGGGTGAGCCGAC

Product: PPE family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 518; Mature: 517

Protein sequence:

>518_residues
MTSALIWMASPPEVHSALLSSGPGPGPVLAAATGWSSLGREYAAVAEELGALLAAVQAGVWQGPSAESFAAACLPYLSWL
TQASADCAAAAARLEAVTAAYAAALVAMPTLAELAANHATHGAMVATNFFGINTIPIAVNEADYVRMWLQAATTMATYQA
VADSAVRSIPDSVPPPRILKSNAQSQHSSSNNSGGADPVDDFIAEILKIITGGRVIWDPEAGTVNGLPYDAYTNPGTLMW
WIARSLELLQDFQEFAKLLFTNPVKAFQFLVDLILFDWPTHMLQLATWLAENPQLLVAALTPAISGLGAVSGLAGLTGLV
PQPPVVPAPAPDAVVPTVLPLAGTATPTTAPASAPAAGAAPGPPAGTATATSASVPTSAGGFPPYLVGSGPGIDFDAGTP
AGSRRAQPAADNVTAVAAAQVSARHQARRRRRAAAKERGNADEFVDMDSGPAIPPSGERDAWASNSGVGGLGFAGTASNE
TVAAPAGLTTLADDEFQCGPRMPMLPGAWDLGTWDRGD

Sequences:

>Translated_518_residues
MTSALIWMASPPEVHSALLSSGPGPGPVLAAATGWSSLGREYAAVAEELGALLAAVQAGVWQGPSAESFAAACLPYLSWL
TQASADCAAAAARLEAVTAAYAAALVAMPTLAELAANHATHGAMVATNFFGINTIPIAVNEADYVRMWLQAATTMATYQA
VADSAVRSIPDSVPPPRILKSNAQSQHSSSNNSGGADPVDDFIAEILKIITGGRVIWDPEAGTVNGLPYDAYTNPGTLMW
WIARSLELLQDFQEFAKLLFTNPVKAFQFLVDLILFDWPTHMLQLATWLAENPQLLVAALTPAISGLGAVSGLAGLTGLV
PQPPVVPAPAPDAVVPTVLPLAGTATPTTAPASAPAAGAAPGPPAGTATATSASVPTSAGGFPPYLVGSGPGIDFDAGTP
AGSRRAQPAADNVTAVAAAQVSARHQARRRRRAAAKERGNADEFVDMDSGPAIPPSGERDAWASNSGVGGLGFAGTASNE
TVAAPAGLTTLADDEFQCGPRMPMLPGAWDLGTWDRGD
>Mature_517_residues
TSALIWMASPPEVHSALLSSGPGPGPVLAAATGWSSLGREYAAVAEELGALLAAVQAGVWQGPSAESFAAACLPYLSWLT
QASADCAAAAARLEAVTAAYAAALVAMPTLAELAANHATHGAMVATNFFGINTIPIAVNEADYVRMWLQAATTMATYQAV
ADSAVRSIPDSVPPPRILKSNAQSQHSSSNNSGGADPVDDFIAEILKIITGGRVIWDPEAGTVNGLPYDAYTNPGTLMWW
IARSLELLQDFQEFAKLLFTNPVKAFQFLVDLILFDWPTHMLQLATWLAENPQLLVAALTPAISGLGAVSGLAGLTGLVP
QPPVVPAPAPDAVVPTVLPLAGTATPTTAPASAPAAGAAPGPPAGTATATSASVPTSAGGFPPYLVGSGPGIDFDAGTPA
GSRRAQPAADNVTAVAAAQVSARHQARRRRRAAAKERGNADEFVDMDSGPAIPPSGERDAWASNSGVGGLGFAGTASNET
VAAPAGLTTLADDEFQCGPRMPMLPGAWDLGTWDRGD

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PPE family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PPE11_MYCTU (Q6MX41)

Other databases:

- EMBL:   BX842573
- EMBL:   AE000516
- PIR:   F70831
- RefSeq:   NP_334878.1
- RefSeq:   YP_177727.1
- HSSP:   Q79FE1
- ProteinModelPortal:   Q6MX41
- SMR:   Q6MX41
- EnsemblBacteria:   EBMYCT00000001138
- EnsemblBacteria:   EBMYCT00000069016
- GeneID:   886317
- GeneID:   923801
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT0469
- KEGG:   mtu:Rv0453
- TIGR:   MT0469
- TubercuList:   Rv0453
- GeneTree:   EBGT00050000014875
- HOGENOM:   HBG572308
- OMA:   ETHHARR
- ProtClustDB:   CLSK799711
- GO:   GO:0005829
- InterPro:   IPR000030

Pfam domain/function: PF00823 PPE

EC number: NA

Molecular weight: Translated: 52837; Mature: 52706

Theoretical pI: Translated: 4.36; Mature: 4.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSALIWMASPPEVHSALLSSGPGPGPVLAAATGWSSLGREYAAVAEELGALLAAVQAGV
CCCEEEEECCCHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHC
WQGPSAESFAAACLPYLSWLTQASADCAAAAARLEAVTAAYAAALVAMPTLAELAANHAT
CCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
HGAMVATNFFGINTIPIAVNEADYVRMWLQAATTMATYQAVADSAVRSIPDSVPPPRILK
CCCEEEEEECCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
SNAQSQHSSSNNSGGADPVDDFIAEILKIITGGRVIWDPEAGTVNGLPYDAYTNPGTLMW
CCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCCCHHHH
WIARSLELLQDFQEFAKLLFTNPVKAFQFLVDLILFDWPTHMLQLATWLAENPQLLVAAL
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCEEEEHH
TPAISGLGAVSGLAGLTGLVPQPPVVPAPAPDAVVPTVLPLAGTATPTTAPASAPAAGAA
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCC
PGPPAGTATATSASVPTSAGGFPPYLVGSGPGIDFDAGTPAGSRRAQPAADNVTAVAAAQ
CCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
VSARHQARRRRRAAAKERGNADEFVDMDSGPAIPPSGERDAWASNSGVGGLGFAGTASNE
HHHHHHHHHHHHHHHHHCCCCHHEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TVAAPAGLTTLADDEFQCGPRMPMLPGAWDLGTWDRGD
CEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TSALIWMASPPEVHSALLSSGPGPGPVLAAATGWSSLGREYAAVAEELGALLAAVQAGV
CCEEEEECCCHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHC
WQGPSAESFAAACLPYLSWLTQASADCAAAAARLEAVTAAYAAALVAMPTLAELAANHAT
CCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
HGAMVATNFFGINTIPIAVNEADYVRMWLQAATTMATYQAVADSAVRSIPDSVPPPRILK
CCCEEEEEECCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
SNAQSQHSSSNNSGGADPVDDFIAEILKIITGGRVIWDPEAGTVNGLPYDAYTNPGTLMW
CCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCCCHHHH
WIARSLELLQDFQEFAKLLFTNPVKAFQFLVDLILFDWPTHMLQLATWLAENPQLLVAAL
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCEEEEHH
TPAISGLGAVSGLAGLTGLVPQPPVVPAPAPDAVVPTVLPLAGTATPTTAPASAPAAGAA
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCC
PGPPAGTATATSASVPTSAGGFPPYLVGSGPGIDFDAGTPAGSRRAQPAADNVTAVAAAQ
CCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
VSARHQARRRRRAAAKERGNADEFVDMDSGPAIPPSGERDAWASNSGVGGLGFAGTASNE
HHHHHHHHHHHHHHHHHCCCCHHEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TVAAPAGLTTLADDEFQCGPRMPMLPGAWDLGTWDRGD
CEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036