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The map label for this gene is yciK [C]

Identifier: 121635979

GI number: 121635979

Start: 104997

End: 105908

Strand: Direct

Name: yciK [C]

Synonym: BCG_0099

Alternate gene names: 121635979

Gene position: 104997-105908 (Clockwise)

Preceding gene: 121635976

Following gene: 121635982

Centisome position: 2.4

GC content: 65.79

Gene sequence:

>912_bases
ATGACCAAATGGACTGCCGCCGACATTCCTGACCAGACCGGCCGGACCGCCGTCATCACGGGGGCCAACACCGGACTTGG
ATTCGAGACCGCCGCAGCGCTTGCCGCCCATGGTGCACACGTGGTGCTGGCTGTGCGCAACCTCGACAAGGGCAAGCAGG
CGGCGGCACGCATCACCGAGGCCACCCCCGGCGCCGAAGTAGAGCTTCAGGAGCTTGACCTGACCTCGCTGGCGTCGGTG
CGCGCCGCCGCGGCACAGCTGAAGTCTGACCACCAGCGCATCGACCTGCTGATCAACAACGCCGGGGTGATGTATACACC
CCGACAGACCACAGCAGACGGCTTCGAGATGCAGTTCGGCACCAACCACTTGGGCCATTTCGCGTTGACCGGCCTGTTGA
TTGATCGACTGCTGCCCGTCGCCGGTTCACGAGTGGTCACCATCAGCAGCGTCGGCCATCGCATCCGTGCCGCAATCCAT
TTCGACGACCTCCAGTGGGAACGCCGGTACAGGCGGGTCGCCGCCTACGGCCAAGCCAAGCTCGCCAACCTGCTGTTCAC
TTATGAACTTCAGCGTCGGTTAGCACCGGGCGGAACCACCATCGCGGTCGCGTCGCACCCGGGAGTGTCCAACACCGAAC
TGGTCCGCAACATGCCACGGCCGCTCGTCGCGGTGGCGGCCATACTGGCGCCGCTGATGCAAGACGCCGAACTGGGGGCC
CTGCCGACATTGCGTGCCGCCACCGATCCCGCGGTGCGCGGCGGCCAGTACTTCGGACCCGATGGCTTCGGTGAAATACG
GGGCTACCCGAAGGTGGTGGCCTCCAGCGCCCAGTCTCACGACGAGCAGCTGCAGCGCCGCCTGTGGGCTGTGTCCGAAG
AGCTCACCGGGGTCGTCTATCCCGTCGGATGA

Upstream 100 bases:

>100_bases
CGTACCTCCGAAAGCCTTGACAAAGCGGGGCGCGCGTTCCGTATAGTTCGGCTAAGCGGAGCGCTCGCCCCGCTTAGTCA
AAGCATAGCGAGGAGCCCTC

Downstream 100 bases:

>100_bases
GCCGGACTCAACGGCAACGGTTGGTCAACACTCGACGATGTTGACTGCGACGTTGATGGCGAGCCCGCCGGCCGAGGTTT
CCTTGTACTTGGTGTGCATG

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MTKWTAADIPDQTGRTAVITGANTGLGFETAAALAAHGAHVVLAVRNLDKGKQAAARITEATPGAEVELQELDLTSLASV
RAAAAQLKSDHQRIDLLINNAGVMYTPRQTTADGFEMQFGTNHLGHFALTGLLIDRLLPVAGSRVVTISSVGHRIRAAIH
FDDLQWERRYRRVAAYGQAKLANLLFTYELQRRLAPGGTTIAVASHPGVSNTELVRNMPRPLVAVAAILAPLMQDAELGA
LPTLRAATDPAVRGGQYFGPDGFGEIRGYPKVVASSAQSHDEQLQRRLWAVSEELTGVVYPVG

Sequences:

>Translated_303_residues
MTKWTAADIPDQTGRTAVITGANTGLGFETAAALAAHGAHVVLAVRNLDKGKQAAARITEATPGAEVELQELDLTSLASV
RAAAAQLKSDHQRIDLLINNAGVMYTPRQTTADGFEMQFGTNHLGHFALTGLLIDRLLPVAGSRVVTISSVGHRIRAAIH
FDDLQWERRYRRVAAYGQAKLANLLFTYELQRRLAPGGTTIAVASHPGVSNTELVRNMPRPLVAVAAILAPLMQDAELGA
LPTLRAATDPAVRGGQYFGPDGFGEIRGYPKVVASSAQSHDEQLQRRLWAVSEELTGVVYPVG
>Mature_302_residues
TKWTAADIPDQTGRTAVITGANTGLGFETAAALAAHGAHVVLAVRNLDKGKQAAARITEATPGAEVELQELDLTSLASVR
AAAAQLKSDHQRIDLLINNAGVMYTPRQTTADGFEMQFGTNHLGHFALTGLLIDRLLPVAGSRVVTISSVGHRIRAAIHF
DDLQWERRYRRVAAYGQAKLANLLFTYELQRRLAPGGTTIAVASHPGVSNTELVRNMPRPLVAVAAILAPLMQDAELGAL
PTLRAATDPAVRGGQYFGPDGFGEIRGYPKVVASSAQSHDEQLQRRLWAVSEELTGVVYPVG

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI225579078, Length=305, Percent_Identity=44.2622950819672, Blast_Score=206, Evalue=3e-53,
Organism=Homo sapiens, GI186928839, Length=287, Percent_Identity=43.205574912892, Blast_Score=190, Evalue=1e-48,
Organism=Homo sapiens, GI166795268, Length=285, Percent_Identity=41.0526315789474, Blast_Score=184, Evalue=7e-47,
Organism=Homo sapiens, GI10190746, Length=304, Percent_Identity=39.1447368421053, Blast_Score=176, Evalue=2e-44,
Organism=Homo sapiens, GI7706523, Length=297, Percent_Identity=37.3737373737374, Blast_Score=169, Evalue=2e-42,
Organism=Homo sapiens, GI19923931, Length=262, Percent_Identity=43.8931297709924, Blast_Score=169, Evalue=3e-42,
Organism=Homo sapiens, GI193804850, Length=299, Percent_Identity=38.7959866220736, Blast_Score=168, Evalue=7e-42,
Organism=Homo sapiens, GI146231950, Length=296, Percent_Identity=37.8378378378378, Blast_Score=135, Evalue=3e-32,
Organism=Homo sapiens, GI7705421, Length=246, Percent_Identity=27.6422764227642, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI13375997, Length=176, Percent_Identity=32.3863636363636, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI72534732, Length=160, Percent_Identity=32.5, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI20149619, Length=143, Percent_Identity=35.6643356643357, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17532791, Length=305, Percent_Identity=34.7540983606557, Blast_Score=147, Evalue=7e-36,
Organism=Caenorhabditis elegans, GI193207620, Length=306, Percent_Identity=34.3137254901961, Blast_Score=140, Evalue=9e-34,
Organism=Caenorhabditis elegans, GI17532805, Length=306, Percent_Identity=34.640522875817, Blast_Score=138, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17558006, Length=295, Percent_Identity=31.1864406779661, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI71992402, Length=298, Percent_Identity=32.5503355704698, Blast_Score=124, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI17535059, Length=297, Percent_Identity=31.986531986532, Blast_Score=109, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI32565532, Length=136, Percent_Identity=41.1764705882353, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17505416, Length=309, Percent_Identity=26.8608414239482, Blast_Score=97, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI72001364, Length=298, Percent_Identity=29.8657718120805, Blast_Score=95, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI115533174, Length=291, Percent_Identity=29.2096219931272, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI115533172, Length=291, Percent_Identity=29.2096219931272, Blast_Score=83, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6324820, Length=332, Percent_Identity=29.8192771084337, Blast_Score=108, Evalue=9e-25,
Organism=Drosophila melanogaster, GI28573296, Length=295, Percent_Identity=44.0677966101695, Blast_Score=208, Evalue=4e-54,
Organism=Drosophila melanogaster, GI19921754, Length=295, Percent_Identity=42.7118644067797, Blast_Score=197, Evalue=9e-51,
Organism=Drosophila melanogaster, GI22024069, Length=295, Percent_Identity=41.6949152542373, Blast_Score=194, Evalue=8e-50,
Organism=Drosophila melanogaster, GI161076371, Length=295, Percent_Identity=40.6779661016949, Blast_Score=183, Evalue=1e-46,
Organism=Drosophila melanogaster, GI24586328, Length=293, Percent_Identity=39.5904436860068, Blast_Score=181, Evalue=6e-46,
Organism=Drosophila melanogaster, GI45554248, Length=253, Percent_Identity=43.0830039525692, Blast_Score=160, Evalue=9e-40,
Organism=Drosophila melanogaster, GI24640117, Length=253, Percent_Identity=43.0830039525692, Blast_Score=160, Evalue=9e-40,
Organism=Drosophila melanogaster, GI20129347, Length=298, Percent_Identity=35.9060402684564, Blast_Score=145, Evalue=4e-35,
Organism=Drosophila melanogaster, GI24647946, Length=250, Percent_Identity=37.2, Blast_Score=142, Evalue=4e-34,
Organism=Drosophila melanogaster, GI45553409, Length=250, Percent_Identity=37.2, Blast_Score=141, Evalue=4e-34,
Organism=Drosophila melanogaster, GI24647948, Length=250, Percent_Identity=37.2, Blast_Score=141, Evalue=4e-34,
Organism=Drosophila melanogaster, GI24656154, Length=262, Percent_Identity=36.2595419847328, Blast_Score=129, Evalue=2e-30,
Organism=Drosophila melanogaster, GI19922628, Length=262, Percent_Identity=36.2595419847328, Blast_Score=129, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24647931, Length=300, Percent_Identity=35, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI21357041, Length=210, Percent_Identity=30.4761904761905, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI28571526, Length=202, Percent_Identity=31.6831683168317, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 32413; Mature: 32282

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKWTAADIPDQTGRTAVITGANTGLGFETAAALAAHGAHVVLAVRNLDKGKQAAARITE
CCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHC
ATPGAEVELQELDLTSLASVRAAAAQLKSDHQRIDLLINNAGVMYTPRQTTADGFEMQFG
CCCCCCEEEHHCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEECCCCCCCCCEEEECC
TNHLGHFALTGLLIDRLLPVAGSRVVTISSVGHRIRAAIHFDDLQWERRYRRVAAYGQAK
CCHHHHHHHHHHHHHHHHHCCCCCEEEEEHHCCEEEEEEEECCHHHHHHHHHHHHHCHHH
LANLLFTYELQRRLAPGGTTIAVASHPGVSNTELVRNMPRPLVAVAAILAPLMQDAELGA
HHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCCCCC
LPTLRAATDPAVRGGQYFGPDGFGEIRGYPKVVASSAQSHDEQLQRRLWAVSEELTGVVY
CCCCCCCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEE
PVG
ECC
>Mature Secondary Structure 
TKWTAADIPDQTGRTAVITGANTGLGFETAAALAAHGAHVVLAVRNLDKGKQAAARITE
CCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHC
ATPGAEVELQELDLTSLASVRAAAAQLKSDHQRIDLLINNAGVMYTPRQTTADGFEMQFG
CCCCCCEEEHHCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEECCCCCCCCCEEEECC
TNHLGHFALTGLLIDRLLPVAGSRVVTISSVGHRIRAAIHFDDLQWERRYRRVAAYGQAK
CCHHHHHHHHHHHHHHHHHCCCCCEEEEEHHCCEEEEEEEECCHHHHHHHHHHHHHCHHH
LANLLFTYELQRRLAPGGTTIAVASHPGVSNTELVRNMPRPLVAVAAILAPLMQDAELGA
HHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCCCCC
LPTLRAATDPAVRGGQYFGPDGFGEIRGYPKVVASSAQSHDEQLQRRLWAVSEELTGVVY
CCCCCCCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEE
PVG
ECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on the CH-OH group of donors; With NAD or NADP as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8383668 [H]