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The map label for this gene is acoR [H]

Identifier: 121611850

GI number: 121611850

Start: 5476271

End: 5478271

Strand: Direct

Name: acoR [H]

Synonym: Veis_4952

Alternate gene names: 121611850

Gene position: 5476271-5478271 (Clockwise)

Preceding gene: 121611849

Following gene: 121611851

Centisome position: 98.37

GC content: 68.67

Gene sequence:

>2001_bases
ATGACGCCCTCTCGGGAGCATCTCGATGTCGTGATGAACGTCGTGGGCAACGAGGCTGCCTTGACCGCGCTGGCCCTCGA
CAACCCCATCCACCGCTCGTGGCTGCGCTGCTACAACGACTACGGGCTGGATCCCGCCGGGCGCCAGCACATGCGCGTGG
AAAGCTCGGGTGCGCTGCGCGACCGGCACGCCAAGCACCTGGCCTACCTGCACACCGCGCGCGCCGCGATGGAGGAGCTC
TACGCGCGCGTGGCCGACCTGGGTTATGTGCTGCTGCTGGCCGATGCAGACGGCATCACGCTGGACTACCTGGGCCACCG
GGCCGGCGATTCGCCGATCCGCGCCGGCCTGGTGGTCGGCGCCAACTGGCACGAGGCGCACGCCGGCACCAACGGCATCG
GCACCTGCCTGGCGGAATGCCGCACGCTGACCTGCCACTATGACGACCATTTCTATGCCGGCAACCTCGACCTCAGTTGC
ACGGCCACGCCGCTGTTCGATCCTGAGGGCGAGCTTATGGGCGCGCTGGATCTGTCCTCGCTCACAACACCCGATTCACG
CGCGAGCCAGCATCTGATCGGCCACATGGCCTCGATGTATGGCCGCATGATCGAGGATGCCAATTTCCTGCGGCACTTCG
GCCACCGGTGGGTCCTGCGGCTGGGACGCGCCGCGTCGCTCGTCGAGGTCAATGCCGAGGCCTTGCTGGCCTTCGATGCC
GACGGCGTGATCGTCGGTGCCGACAGCGGCGCGCGCCGGCTGCTGCAGACCGTGGACGGGCAGAGCGTGGGGGCGCTGCT
CGGCCAGCCGCTGTCGGCCGTGTTCCGCAACCCGCTGGGCGATGTCATGCGGCTGGCGCGCGCCGGCAACGGCGACAGCA
GTGCACTGCTGCACCCCTGGCTGGGCGAGCCGCGCCAGGCCATGGTGCGTGGGCCGCAGCGCAGGACGCGCATGTCGGGT
GCCACCTCCGTCCAGGCTGATCACCTGCAGGCTGCGCCGCAGGGCGATGTGTCTGCGCTGGAGGCTCTGTCCGACCGCGA
CCCGAAGATGGACGCGCTCATCTCCCAAGCCCGCCGCCTGGCCGGCAGGTCGATCAACATGATCATCCAGGGCGAGACCG
GCACCGGCAAGGAGGTGCTTGCCCAGGCGATCCACCAGGCCAGCTCGCGCGCAGACCGGGCCTTCGTGGCCATCAACTGC
GCGGCCATCCCCGAATCGTTGATCGAAAGCGAACTGTTCGGCTACCTGCCGGGTACTTTTACCGGTGCGCGCAGCCGCGG
CATGGTGGGCCTGATCCAGCGGGCGGACGGCGGCACCTTGTTCCTTGACGAGATCGGCGACATGCCGCTGGCACTGCAGA
CGCGGTTGCTGCGAGTGCTGGCCGAACGCGAGCTGCTGCCCCTGGGTGCCGACAAACCCATCCCCTTGGCCTTGACCGTA
CTGGCAGCTTCGCACCGCAACCTACGCGAGCGCATTTCAGCCGGGCAGTTCCGCGAAGACCTCTACTACCGTCTCAGCGG
CGCCACGCTGAGCCTGCCGCCGCTACGGGAGCGGCAGGACCGCGCGTACCTGGTCCGCCGCATCCTTGGCGAAGAGGCCA
CCGCCATCGACGCCAACGGCCACCTCACCGTGCAAGCGATGGAACTGCTGCTGCGTTATCCCTGGCCTGGCAACATCCGC
GAGTTGCGCAACGTGCTGCGCTACGCCCTTTCGATGGCTGAAGGCCATGGCATCGGCGCCCGCGACCTGCCACTGGAGGT
GCAACTGGTCGATGCGCCGGCCCCAGTCTTGCTGGCGACTGTGCCCGCACCGCCCGCCATCGACGTAGCCCCCGGTGGGG
AGGACGCCGATGCCAGCCCCGAGGTGCACCAACTGCTGGGCGCCCTGCGGCGCCATCATTGGGTGATCGCCGATGTGGCG
CGCGAGCTGTCCACGTGCCGCGCCACGGTGTACAGGCGCATGAAGCGACACGGCATCGTCGCGCCCACGCAGTTCTGTTG
A

Upstream 100 bases:

>100_bases
GCGCGCGCTGCAACCCTATACTCGCTCGGACCAAGCGCACAGCCACGCGGCGCATGCCGCAGGGAACCAGAGGCGCCGAC
ACTCCGAAGGAGACAACAGT

Downstream 100 bases:

>100_bases
GCATCAAACGCCGTGTAGATGACAAGTGGCCGCACCCACGTACTCGTCGTGGCTGAACCAGGTGGAGAACTGGCTCTCGC
GCATTCAGCGTGATGTCATA

Product: Fis family GAF modulated sigma54 specific transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 666; Mature: 665

Protein sequence:

>666_residues
MTPSREHLDVVMNVVGNEAALTALALDNPIHRSWLRCYNDYGLDPAGRQHMRVESSGALRDRHAKHLAYLHTARAAMEEL
YARVADLGYVLLLADADGITLDYLGHRAGDSPIRAGLVVGANWHEAHAGTNGIGTCLAECRTLTCHYDDHFYAGNLDLSC
TATPLFDPEGELMGALDLSSLTTPDSRASQHLIGHMASMYGRMIEDANFLRHFGHRWVLRLGRAASLVEVNAEALLAFDA
DGVIVGADSGARRLLQTVDGQSVGALLGQPLSAVFRNPLGDVMRLARAGNGDSSALLHPWLGEPRQAMVRGPQRRTRMSG
ATSVQADHLQAAPQGDVSALEALSDRDPKMDALISQARRLAGRSINMIIQGETGTGKEVLAQAIHQASSRADRAFVAINC
AAIPESLIESELFGYLPGTFTGARSRGMVGLIQRADGGTLFLDEIGDMPLALQTRLLRVLAERELLPLGADKPIPLALTV
LAASHRNLRERISAGQFREDLYYRLSGATLSLPPLRERQDRAYLVRRILGEEATAIDANGHLTVQAMELLLRYPWPGNIR
ELRNVLRYALSMAEGHGIGARDLPLEVQLVDAPAPVLLATVPAPPAIDVAPGGEDADASPEVHQLLGALRRHHWVIADVA
RELSTCRATVYRRMKRHGIVAPTQFC

Sequences:

>Translated_666_residues
MTPSREHLDVVMNVVGNEAALTALALDNPIHRSWLRCYNDYGLDPAGRQHMRVESSGALRDRHAKHLAYLHTARAAMEEL
YARVADLGYVLLLADADGITLDYLGHRAGDSPIRAGLVVGANWHEAHAGTNGIGTCLAECRTLTCHYDDHFYAGNLDLSC
TATPLFDPEGELMGALDLSSLTTPDSRASQHLIGHMASMYGRMIEDANFLRHFGHRWVLRLGRAASLVEVNAEALLAFDA
DGVIVGADSGARRLLQTVDGQSVGALLGQPLSAVFRNPLGDVMRLARAGNGDSSALLHPWLGEPRQAMVRGPQRRTRMSG
ATSVQADHLQAAPQGDVSALEALSDRDPKMDALISQARRLAGRSINMIIQGETGTGKEVLAQAIHQASSRADRAFVAINC
AAIPESLIESELFGYLPGTFTGARSRGMVGLIQRADGGTLFLDEIGDMPLALQTRLLRVLAERELLPLGADKPIPLALTV
LAASHRNLRERISAGQFREDLYYRLSGATLSLPPLRERQDRAYLVRRILGEEATAIDANGHLTVQAMELLLRYPWPGNIR
ELRNVLRYALSMAEGHGIGARDLPLEVQLVDAPAPVLLATVPAPPAIDVAPGGEDADASPEVHQLLGALRRHHWVIADVA
RELSTCRATVYRRMKRHGIVAPTQFC
>Mature_665_residues
TPSREHLDVVMNVVGNEAALTALALDNPIHRSWLRCYNDYGLDPAGRQHMRVESSGALRDRHAKHLAYLHTARAAMEELY
ARVADLGYVLLLADADGITLDYLGHRAGDSPIRAGLVVGANWHEAHAGTNGIGTCLAECRTLTCHYDDHFYAGNLDLSCT
ATPLFDPEGELMGALDLSSLTTPDSRASQHLIGHMASMYGRMIEDANFLRHFGHRWVLRLGRAASLVEVNAEALLAFDAD
GVIVGADSGARRLLQTVDGQSVGALLGQPLSAVFRNPLGDVMRLARAGNGDSSALLHPWLGEPRQAMVRGPQRRTRMSGA
TSVQADHLQAAPQGDVSALEALSDRDPKMDALISQARRLAGRSINMIIQGETGTGKEVLAQAIHQASSRADRAFVAINCA
AIPESLIESELFGYLPGTFTGARSRGMVGLIQRADGGTLFLDEIGDMPLALQTRLLRVLAERELLPLGADKPIPLALTVL
AASHRNLRERISAGQFREDLYYRLSGATLSLPPLRERQDRAYLVRRILGEEATAIDANGHLTVQAMELLLRYPWPGNIRE
LRNVLRYALSMAEGHGIGARDLPLEVQLVDAPAPVLLATVPAPPAIDVAPGGEDADASPEVHQLLGALRRHHWVIADVAR
ELSTCRATVYRRMKRHGIVAPTQFC

Specific function: Required for sigma-54-dependent transcription of acoXABC [H]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1789233, Length=351, Percent_Identity=39.3162393162393, Blast_Score=227, Evalue=2e-60,
Organism=Escherichia coli, GI1788905, Length=249, Percent_Identity=46.1847389558233, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI1790437, Length=320, Percent_Identity=38.125, Blast_Score=210, Evalue=2e-55,
Organism=Escherichia coli, GI1790299, Length=325, Percent_Identity=41.2307692307692, Blast_Score=209, Evalue=4e-55,
Organism=Escherichia coli, GI87082117, Length=324, Percent_Identity=41.0493827160494, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI1788550, Length=243, Percent_Identity=43.6213991769547, Blast_Score=201, Evalue=1e-52,
Organism=Escherichia coli, GI87082152, Length=335, Percent_Identity=40, Blast_Score=199, Evalue=5e-52,
Organism=Escherichia coli, GI1786524, Length=243, Percent_Identity=48.1481481481481, Blast_Score=199, Evalue=7e-52,
Organism=Escherichia coli, GI1789087, Length=325, Percent_Identity=39.0769230769231, Blast_Score=195, Evalue=9e-51,
Organism=Escherichia coli, GI1787583, Length=337, Percent_Identity=35.6083086053413, Blast_Score=186, Evalue=4e-48,
Organism=Escherichia coli, GI87081872, Length=242, Percent_Identity=38.8429752066116, Blast_Score=159, Evalue=6e-40,
Organism=Escherichia coli, GI1789828, Length=231, Percent_Identity=35.0649350649351, Blast_Score=130, Evalue=4e-31,
Organism=Escherichia coli, GI87081858, Length=651, Percent_Identity=25.3456221198157, Blast_Score=125, Evalue=7e-30,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 72247; Mature: 72116

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPSREHLDVVMNVVGNEAALTALALDNPIHRSWLRCYNDYGLDPAGRQHMRVESSGALR
CCCCHHHHHHHHHHHCCHHHEEEEHHCCHHHHHHHHHHHHCCCCCCCCCCEEECCCCCHH
DRHAKHLAYLHTARAAMEELYARVADLGYVLLLADADGITLDYLGHRAGDSPIRAGLVVG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHCCCCCCCCCEEEEEEC
ANWHEAHAGTNGIGTCLAECRTLTCHYDDHFYAGNLDLSCTATPLFDPEGELMGALDLSS
CCCHHHCCCCCHHHHHHHHHCEEEEEECCCEEECCCCEEEEECCCCCCCCCEEEEEECCC
LTTPDSRASQHLIGHMASMYGRMIEDANFLRHFGHRWVLRLGRAASLVEVNAEALLAFDA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEECCEEEEEECC
DGVIVGADSGARRLLQTVDGQSVGALLGQPLSAVFRNPLGDVMRLARAGNGDSSALLHPW
CCEEEECCHHHHHHHHHHCCCHHHHHHCCCHHHHHHCHHHHHHHHHHCCCCCCCCEECCC
LGEPRQAMVRGPQRRTRMSGATSVQADHLQAAPQGDVSALEALSDRDPKMDALISQARRL
CCCCHHHHHCCCHHHHHCCCCCCCCHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHH
AGRSINMIIQGETGTGKEVLAQAIHQASSRADRAFVAINCAAIPESLIESELFGYLPGTF
CCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEEHHHCCHHHHHHHHHHCCCCCC
TGARSRGMVGLIQRADGGTLFLDEIGDMPLALQTRLLRVLAERELLPLGADKPIPLALTV
CCCCCCCCEEEEEECCCCEEEHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
LAASHRNLRERISAGQFREDLYYRLSGATLSLPPLRERQDRAYLVRRILGEEATAIDANG
HHHHHHHHHHHHHHHHHHHHHHEEECCCEECCCCCHHHHHHHHHHHHHHCCCCEEECCCC
HLTVQAMELLLRYPWPGNIRELRNVLRYALSMAEGHGIGARDLPLEVQLVDAPAPVLLAT
CCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCEEEEE
VPAPPAIDVAPGGEDADASPEVHQLLGALRRHHWVIADVARELSTCRATVYRRMKRHGIV
CCCCCCEECCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
APTQFC
CCCCCC
>Mature Secondary Structure 
TPSREHLDVVMNVVGNEAALTALALDNPIHRSWLRCYNDYGLDPAGRQHMRVESSGALR
CCCHHHHHHHHHHHCCHHHEEEEHHCCHHHHHHHHHHHHCCCCCCCCCCEEECCCCCHH
DRHAKHLAYLHTARAAMEELYARVADLGYVLLLADADGITLDYLGHRAGDSPIRAGLVVG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHCCCCCCCCCEEEEEEC
ANWHEAHAGTNGIGTCLAECRTLTCHYDDHFYAGNLDLSCTATPLFDPEGELMGALDLSS
CCCHHHCCCCCHHHHHHHHHCEEEEEECCCEEECCCCEEEEECCCCCCCCCEEEEEECCC
LTTPDSRASQHLIGHMASMYGRMIEDANFLRHFGHRWVLRLGRAASLVEVNAEALLAFDA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEECCEEEEEECC
DGVIVGADSGARRLLQTVDGQSVGALLGQPLSAVFRNPLGDVMRLARAGNGDSSALLHPW
CCEEEECCHHHHHHHHHHCCCHHHHHHCCCHHHHHHCHHHHHHHHHHCCCCCCCCEECCC
LGEPRQAMVRGPQRRTRMSGATSVQADHLQAAPQGDVSALEALSDRDPKMDALISQARRL
CCCCHHHHHCCCHHHHHCCCCCCCCHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHH
AGRSINMIIQGETGTGKEVLAQAIHQASSRADRAFVAINCAAIPESLIESELFGYLPGTF
CCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEEHHHCCHHHHHHHHHHCCCCCC
TGARSRGMVGLIQRADGGTLFLDEIGDMPLALQTRLLRVLAERELLPLGADKPIPLALTV
CCCCCCCCEEEEEECCCCEEEHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
LAASHRNLRERISAGQFREDLYYRLSGATLSLPPLRERQDRAYLVRRILGEEATAIDANG
HHHHHHHHHHHHHHHHHHHHHHEEECCCEECCCCCHHHHHHHHHHHHHHCCCCEEECCCC
HLTVQAMELLLRYPWPGNIRELRNVLRYALSMAEGHGIGARDLPLEVQLVDAPAPVLLAT
CCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCEEEEE
VPAPPAIDVAPGGEDADASPEVHQLLGALRRHHWVIADVARELSTCRATVYRRMKRHGIV
CCCCCCEECCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
APTQFC
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1378052 [H]