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The map label for this gene is glcD [H]

Identifier: 121611599

GI number: 121611599

Start: 5179136

End: 5180563

Strand: Direct

Name: glcD [H]

Synonym: Veis_4691

Alternate gene names: 121611599

Gene position: 5179136-5180563 (Clockwise)

Preceding gene: 121611598

Following gene: 121611603

Centisome position: 93.04

GC content: 67.37

Gene sequence:

>1428_bases
ATGAGCGACAACGAACTGCTGCAAGGACTGCGCGCCATCGTCGGCGAGAACGGCGCCACCGAGGCACCCGACGCGCTCGC
GCCGCATCTGGTCGACTGGCGCAAGCGCCATGTCGGCGTGGCCGATGCCATCGTCTTCCCGCGCACGACCGAACAGGTAG
CCGACGTGCTGCGCTTCTGCGCGGCGCATGCGATCCGCGTCTTTCCGCAAGGCGGCAACACCAGCGTGTGCGGCGGCTCC
GTGCCGGCGACCGAGGGCCGCAACATCGTGCTCGCGCTCGGCAAGATGAACCGAATCCTCGACCTCAATCCGCGCAACAA
CTCGATGACGGTGCAGGCCGGCTGCGTGCTCGCCGACCTGCAGGAAGCGGCGTCGAAGGTCGACCGCCTGTTCCCGCTGT
CGCTGGGCGCCGAAGGCTCGTGCCAGATCGGCGGCAACATCGCGACCAACGCCGGCGGCACGAACGTCGTCCGCTTCGGC
AACACGCGCGACCTGGTGCTGGGCCTCGAGGTCGTGCTGCCCGACGGCCAGATCTGGAACGGTATCCGGACGCTTCGCAA
GAACAACAGCGGCTACGACCTGAAGAATCTCTTCATCGGCGCCGAGGGAACGCTGGGCGTGGTCACCGCGGCCGCGCTGA
AGCTCTTCCCCAAGCCGAAGTCCGTCGCGGCGGCGCTGATGGGTTTCGAGACCGTCGACGCGGCCGTCGACGAAGGCATT
CGGCTGCAAGGGCTCTTTCCGGGCGAACTGGTCGGGCTCGAGCTGATCTCGCGCTCGGAATTCGAGATCTCGCTGCGCCA
CGGCCATGAGCTTCGCAACCCGTTTCCCGACGGCGTGCCGCCGTGGCTCGTGCTCGTGGAGCTGGCCTCGTCGAGCGTCG
GCGACGCGCTGACCGCGCAATTGCAGGACGCGCTCGAAGCGGCGTACGAATCGGGCGCCTGCCAGGAAGTGGTGGTCGCG
ACCTCGGATCAGCATCGCAACGAGTTCTGGCGGATCCGCCACAACGTGACCGAGGCGAACGGCCGCGAAGGCATGGGCCT
GACGCACGACATCGCGGTGCCGATCTACACGATCCCGGCCTTCATGGAGCGCGCCGCGGCCGCGCTCGCGACGCACTATC
CGCAGGCGACGCAGGTCGTGGTCGGCCACATGGGCGACGGCAACCTGCACTACATCGCGATGTTCTCGCATGCGATCTGG
GCCGAGGTCGCGGACAAGGCCGCGTTCCAGCGCGACCTGAGCCATCGGCTCTACGACATCGCGGCGGAACTGGGCGGCAC
CTTCAGCGCCGAGCACGGCATCGGGTCGCTGCACGTCGACGAGATGCGCGTCTACAAGAACCGGGTCGAGATCGAGCTCA
TGCAGAAGATCAAGTCGCTGGTCGATCCGCAGGACATGATGAATCCGGGACGCGTGCTGCCGTCCTGA

Upstream 100 bases:

>100_bases
AGGGCATCTCGGACCGCGCCGCGGATCGCATCGAGGTCGGCGCGTCGCTCGCGCTGCGCTGGGCCGCGCACAATACCGTC
GTGATCAAGGCGAACCAGGG

Downstream 100 bases:

>100_bases
AGCATCAGGCAGCTTCGGCTGCCTGACGCCCGGCGACGCATCAGATCGTCGTCGTCAGTTCCGGCACGGCCACGAACAGA
TCGGCCACCAGTCCGTAGTC

Product: D-lactate dehydrogenase (cytochrome)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 475; Mature: 474

Protein sequence:

>475_residues
MSDNELLQGLRAIVGENGATEAPDALAPHLVDWRKRHVGVADAIVFPRTTEQVADVLRFCAAHAIRVFPQGGNTSVCGGS
VPATEGRNIVLALGKMNRILDLNPRNNSMTVQAGCVLADLQEAASKVDRLFPLSLGAEGSCQIGGNIATNAGGTNVVRFG
NTRDLVLGLEVVLPDGQIWNGIRTLRKNNSGYDLKNLFIGAEGTLGVVTAAALKLFPKPKSVAAALMGFETVDAAVDEGI
RLQGLFPGELVGLELISRSEFEISLRHGHELRNPFPDGVPPWLVLVELASSSVGDALTAQLQDALEAAYESGACQEVVVA
TSDQHRNEFWRIRHNVTEANGREGMGLTHDIAVPIYTIPAFMERAAAALATHYPQATQVVVGHMGDGNLHYIAMFSHAIW
AEVADKAAFQRDLSHRLYDIAAELGGTFSAEHGIGSLHVDEMRVYKNRVEIELMQKIKSLVDPQDMMNPGRVLPS

Sequences:

>Translated_475_residues
MSDNELLQGLRAIVGENGATEAPDALAPHLVDWRKRHVGVADAIVFPRTTEQVADVLRFCAAHAIRVFPQGGNTSVCGGS
VPATEGRNIVLALGKMNRILDLNPRNNSMTVQAGCVLADLQEAASKVDRLFPLSLGAEGSCQIGGNIATNAGGTNVVRFG
NTRDLVLGLEVVLPDGQIWNGIRTLRKNNSGYDLKNLFIGAEGTLGVVTAAALKLFPKPKSVAAALMGFETVDAAVDEGI
RLQGLFPGELVGLELISRSEFEISLRHGHELRNPFPDGVPPWLVLVELASSSVGDALTAQLQDALEAAYESGACQEVVVA
TSDQHRNEFWRIRHNVTEANGREGMGLTHDIAVPIYTIPAFMERAAAALATHYPQATQVVVGHMGDGNLHYIAMFSHAIW
AEVADKAAFQRDLSHRLYDIAAELGGTFSAEHGIGSLHVDEMRVYKNRVEIELMQKIKSLVDPQDMMNPGRVLPS
>Mature_474_residues
SDNELLQGLRAIVGENGATEAPDALAPHLVDWRKRHVGVADAIVFPRTTEQVADVLRFCAAHAIRVFPQGGNTSVCGGSV
PATEGRNIVLALGKMNRILDLNPRNNSMTVQAGCVLADLQEAASKVDRLFPLSLGAEGSCQIGGNIATNAGGTNVVRFGN
TRDLVLGLEVVLPDGQIWNGIRTLRKNNSGYDLKNLFIGAEGTLGVVTAAALKLFPKPKSVAAALMGFETVDAAVDEGIR
LQGLFPGELVGLELISRSEFEISLRHGHELRNPFPDGVPPWLVLVELASSSVGDALTAQLQDALEAAYESGACQEVVVAT
SDQHRNEFWRIRHNVTEANGREGMGLTHDIAVPIYTIPAFMERAAAALATHYPQATQVVVGHMGDGNLHYIAMFSHAIWA
EVADKAAFQRDLSHRLYDIAAELGGTFSAEHGIGSLHVDEMRVYKNRVEIELMQKIKSLVDPQDMMNPGRVLPS

Specific function: Unknown

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Homo sapiens, GI119964728, Length=460, Percent_Identity=37.1739130434783, Blast_Score=281, Evalue=1e-75,
Organism=Homo sapiens, GI37595756, Length=476, Percent_Identity=33.8235294117647, Blast_Score=211, Evalue=1e-54,
Organism=Homo sapiens, GI37595754, Length=499, Percent_Identity=32.4649298597194, Blast_Score=200, Evalue=3e-51,
Organism=Homo sapiens, GI4501993, Length=257, Percent_Identity=28.0155642023346, Blast_Score=86, Evalue=1e-16,
Organism=Escherichia coli, GI1789351, Length=441, Percent_Identity=28.7981859410431, Blast_Score=166, Evalue=4e-42,
Organism=Escherichia coli, GI1787977, Length=506, Percent_Identity=24.3083003952569, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI48994907, Length=499, Percent_Identity=23.0460921843687, Blast_Score=93, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17534361, Length=472, Percent_Identity=30.5084745762712, Blast_Score=233, Evalue=2e-61,
Organism=Caenorhabditis elegans, GI71992373, Length=479, Percent_Identity=30.4801670146138, Blast_Score=169, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI71992381, Length=479, Percent_Identity=29.6450939457203, Blast_Score=161, Evalue=5e-40,
Organism=Caenorhabditis elegans, GI71992392, Length=363, Percent_Identity=32.5068870523416, Blast_Score=149, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI17556096, Length=470, Percent_Identity=23.6170212765957, Blast_Score=96, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6320764, Length=484, Percent_Identity=33.0578512396694, Blast_Score=256, Evalue=6e-69,
Organism=Saccharomyces cerevisiae, GI6320023, Length=478, Percent_Identity=30.5439330543933, Blast_Score=250, Evalue=3e-67,
Organism=Saccharomyces cerevisiae, GI6320027, Length=450, Percent_Identity=28.6666666666667, Blast_Score=177, Evalue=5e-45,
Organism=Drosophila melanogaster, GI18921117, Length=446, Percent_Identity=33.4080717488789, Blast_Score=240, Evalue=2e-63,
Organism=Drosophila melanogaster, GI24639277, Length=446, Percent_Identity=33.4080717488789, Blast_Score=240, Evalue=2e-63,
Organism=Drosophila melanogaster, GI24639275, Length=446, Percent_Identity=33.4080717488789, Blast_Score=240, Evalue=2e-63,
Organism=Drosophila melanogaster, GI24653753, Length=210, Percent_Identity=31.9047619047619, Blast_Score=97, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR016164
- InterPro:   IPR016168
- InterPro:   IPR004113
- InterPro:   IPR004490
- InterPro:   IPR006094
- InterPro:   IPR016171 [H]

Pfam domain/function: PF02913 FAD-oxidase_C; PF01565 FAD_binding_4 [H]

EC number: NA

Molecular weight: Translated: 51111; Mature: 50980

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDNELLQGLRAIVGENGATEAPDALAPHLVDWRKRHVGVADAIVFPRTTEQVADVLRFC
CCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHEEECCCCHHHHHHHHHHH
AAHAIRVFPQGGNTSVCGGSVPATEGRNIVLALGKMNRILDLNPRNNSMTVQAGCVLADL
HHHHEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCEEECCCCCCCEEEECCHHHHHH
QEAASKVDRLFPLSLGAEGSCQIGGNIATNAGGTNVVRFGNTRDLVLGLEVVLPDGQIWN
HHHHHHHHHCCCCCCCCCCCEEECCEEEECCCCCCEEEECCCCEEEEEEEEEECCCHHHH
GIRTLRKNNSGYDLKNLFIGAEGTLGVVTAAALKLFPKPKSVAAALMGFETVDAAVDEGI
HHHHHHCCCCCCCHHHEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCC
RLQGLFPGELVGLELISRSEFEISLRHGHELRNPFPDGVPPWLVLVELASSSVGDALTAQ
EEEECCCCHHHHHHHHCCCCEEEEECCCCHHCCCCCCCCCHHHHHHHHHCCCCCHHHHHH
LQDALEAAYESGACQEVVVATSDQHRNEFWRIRHNVTEANGREGMGLTHDIAVPIYTIPA
HHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCEEECCCHHHHHHH
FMERAAAALATHYPQATQVVVGHMGDGNLHYIAMFSHAIWAEVADKAAFQRDLSHRLYDI
HHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAELGGTFSAEHGIGSLHVDEMRVYKNRVEIELMQKIKSLVDPQDMMNPGRVLPS
HHHHCCCEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCC
>Mature Secondary Structure 
SDNELLQGLRAIVGENGATEAPDALAPHLVDWRKRHVGVADAIVFPRTTEQVADVLRFC
CHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHEEECCCCHHHHHHHHHHH
AAHAIRVFPQGGNTSVCGGSVPATEGRNIVLALGKMNRILDLNPRNNSMTVQAGCVLADL
HHHHEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCEEECCCCCCCEEEECCHHHHHH
QEAASKVDRLFPLSLGAEGSCQIGGNIATNAGGTNVVRFGNTRDLVLGLEVVLPDGQIWN
HHHHHHHHHCCCCCCCCCCCEEECCEEEECCCCCCEEEECCCCEEEEEEEEEECCCHHHH
GIRTLRKNNSGYDLKNLFIGAEGTLGVVTAAALKLFPKPKSVAAALMGFETVDAAVDEGI
HHHHHHCCCCCCCHHHEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCC
RLQGLFPGELVGLELISRSEFEISLRHGHELRNPFPDGVPPWLVLVELASSSVGDALTAQ
EEEECCCCHHHHHHHHCCCCEEEEECCCCHHCCCCCCCCCHHHHHHHHHCCCCCHHHHHH
LQDALEAAYESGACQEVVVATSDQHRNEFWRIRHNVTEANGREGMGLTHDIAVPIYTIPA
HHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCEEECCCHHHHHHH
FMERAAAALATHYPQATQVVVGHMGDGNLHYIAMFSHAIWAEVADKAAFQRDLSHRLYDI
HHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAELGGTFSAEHGIGSLHVDEMRVYKNRVEIELMQKIKSLVDPQDMMNPGRVLPS
HHHHCCCEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]