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The map label for this gene is potC [H]

Identifier: 121611597

GI number: 121611597

Start: 5177165

End: 5177995

Strand: Direct

Name: potC [H]

Synonym: Veis_4689

Alternate gene names: 121611597

Gene position: 5177165-5177995 (Clockwise)

Preceding gene: 121611596

Following gene: 121611598

Centisome position: 93.0

GC content: 64.02

Gene sequence:

>831_bases
ATGAGCACATCGGCATCGCGCGGCGTGATCGATCGCCAGGGCAACTTCTACGGCGGCGTGCGCAACCTGCTGGCCGTCTT
CGTCTACGCGTTCATCTTGGTACCGACGCTGATCGTTATCCCGATCTCCTTCGGCGGGTCGGGCGAGCTGTCCTTTCCGC
CGCGGGTCTGGACCCTCGACCTCTACGGCCAGCTCTTCTCGTCCACGCCATGGATGGCGTCGATCCTGCAGAGCCTGAAG
GTCGCGGTCATCACAACGATCGTGTCGATGCTGATCGGCATCCCGGCCTCGTACGGCCTGGTGCGCTTCGAGTTCCCCGG
CAAGAAGCTGGTCATGCTGCTGCTGATGAGCCCGATCCTCGTGCCCGTCATTGTGATCTCGCTCGGTCTGTACCTTTACC
TGTCGCGACTCCAGGTCGTCGGCACGACCATCGGCCTCGTGGCGAGCCATACCGCCTACGTCGTGCCGTTCATGATGATG
ACCGTGATGGCAGGCGTGCGAAAGCTCGACCCCGCGCTGGAGTTCGCGGCGACCATCATGGGCGCCAGCCGCTCGACCGT
GTTCTTCAAGGTCGTGCTGCCGCAGCTCAAGCCGTCGCTCCTGGCGGGCGCGCTGTTCGCGTTCCTGGTCTCGTTCGACG
AGGTCGTGATCGCCTGGTTCCTGACCAGCCCGTCGACCACCACGCTGCCCGTCAAGATGTACAGCAGCATCCAGTGGGAC
ATTTCCCCCGTGATTGCCGCGGTCTCCGCGTTGCTCACGGCCCTGTCGTTCGTCTTCTGCTGCATCTCCGTCTTGTTCCA
GCCGGCGGCGCCGAGCGACGGCAATCCCTGA

Upstream 100 bases:

>100_bases
TGGCGTCGGCCATCGGCGTCATCCTGCTGGGCATCGTCACGCTGGCCGCCATCCTCGCCGACCAGGCGAAGCGGTTCGGC
AGCCGCCCCGGGGTGCCGGC

Downstream 100 bases:

>100_bases
CACCATGAATGCCAGCACCCAAGAACGTCGAAACATAATGAAGATGATCAGTCCGACTCCCGACGACGCCATGATCGTCT
TCGACGGCGTGAGCAAGTCG

Product: binding-protein-dependent transport systems inner membrane component

Products: Phosphate; putrescine [Cytoplasm]; ADP; spermidine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 275

Protein sequence:

>276_residues
MSTSASRGVIDRQGNFYGGVRNLLAVFVYAFILVPTLIVIPISFGGSGELSFPPRVWTLDLYGQLFSSTPWMASILQSLK
VAVITTIVSMLIGIPASYGLVRFEFPGKKLVMLLLMSPILVPVIVISLGLYLYLSRLQVVGTTIGLVASHTAYVVPFMMM
TVMAGVRKLDPALEFAATIMGASRSTVFFKVVLPQLKPSLLAGALFAFLVSFDEVVIAWFLTSPSTTTLPVKMYSSIQWD
ISPVIAAVSALLTALSFVFCCISVLFQPAAPSDGNP

Sequences:

>Translated_276_residues
MSTSASRGVIDRQGNFYGGVRNLLAVFVYAFILVPTLIVIPISFGGSGELSFPPRVWTLDLYGQLFSSTPWMASILQSLK
VAVITTIVSMLIGIPASYGLVRFEFPGKKLVMLLLMSPILVPVIVISLGLYLYLSRLQVVGTTIGLVASHTAYVVPFMMM
TVMAGVRKLDPALEFAATIMGASRSTVFFKVVLPQLKPSLLAGALFAFLVSFDEVVIAWFLTSPSTTTLPVKMYSSIQWD
ISPVIAAVSALLTALSFVFCCISVLFQPAAPSDGNP
>Mature_275_residues
STSASRGVIDRQGNFYGGVRNLLAVFVYAFILVPTLIVIPISFGGSGELSFPPRVWTLDLYGQLFSSTPWMASILQSLKV
AVITTIVSMLIGIPASYGLVRFEFPGKKLVMLLLMSPILVPVIVISLGLYLYLSRLQVVGTTIGLVASHTAYVVPFMMMT
VMAGVRKLDPALEFAATIMGASRSTVFFKVVLPQLKPSLLAGALFAFLVSFDEVVIAWFLTSPSTTTLPVKMYSSIQWDI
SPVIAAVSALLTALSFVFCCISVLFQPAAPSDGNP

Specific function: Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine [H]

COG id: COG1177

COG function: function code E; ABC-type spermidine/putrescine transport system, permease component II

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787368, Length=222, Percent_Identity=31.0810810810811, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787081, Length=231, Percent_Identity=29.004329004329, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1787369, Length=196, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1787714, Length=208, Percent_Identity=31.25, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788764, Length=145, Percent_Identity=31.0344827586207, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 29717; Mature: 29586

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTSASRGVIDRQGNFYGGVRNLLAVFVYAFILVPTLIVIPISFGGSGELSFPPRVWTLD
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEHH
LYGQLFSSTPWMASILQSLKVAVITTIVSMLIGIPASYGLVRFEFPGKKLVMLLLMSPIL
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHH
VPVIVISLGLYLYLSRLQVVGTTIGLVASHTAYVVPFMMMTVMAGVRKLDPALEFAATIM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GASRSTVFFKVVLPQLKPSLLAGALFAFLVSFDEVVIAWFLTSPSTTTLPVKMYSSIQWD
CCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHCCCCC
ISPVIAAVSALLTALSFVFCCISVLFQPAAPSDGNP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
STSASRGVIDRQGNFYGGVRNLLAVFVYAFILVPTLIVIPISFGGSGELSFPPRVWTLD
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEHH
LYGQLFSSTPWMASILQSLKVAVITTIVSMLIGIPASYGLVRFEFPGKKLVMLLLMSPIL
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHH
VPVIVISLGLYLYLSRLQVVGTTIGLVASHTAYVVPFMMMTVMAGVRKLDPALEFAATIM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GASRSTVFFKVVLPQLKPSLLAGALFAFLVSFDEVVIAWFLTSPSTTTLPVKMYSSIQWD
CCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHCCCCC
ISPVIAAVSALLTALSFVFCCISVLFQPAAPSDGNP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Putrescine [Periplasm]; H2O; ATP; spermidine [Periplasm] [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] ATP + spermidine [Periplasm] + H2O = ADP + phosphate + spermidine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]