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The map label for this gene is livK [C]

Identifier: 121611554

GI number: 121611554

Start: 5138340

End: 5139494

Strand: Direct

Name: livK [C]

Synonym: Veis_4646

Alternate gene names: 121611554

Gene position: 5138340-5139494 (Clockwise)

Preceding gene: 121611553

Following gene: 121611555

Centisome position: 92.3

GC content: 59.65

Gene sequence:

>1155_bases
ATGCACCTTTCTTCTACTTCCCGTCTCGCCTCCTTGCTGATGGCGGGGCTGATTTCCGTCGCTGCGATGCCTGCAGCGTC
CCAACCTATCAAGCTGGGCATCATTACCGACCGGGTGGGTGCCGCCAAGCCGTACGCGGAACCTGTTTTGCAGGGCGCGC
AAGTGGCCGCCAAGGAGCTCAATGCCAGCGGTGGCGTGTTGGGACGCCCGATCGAGCTCCTGGTGGAAGATGATCAGGGC
CGCCCGGATCTCTCGGCAACAGCGGCACGCAAGCTCGTCGATTCTGGTGTGGCTTTCATCCTGTCGATTTCCTGGACCTC
GGCCACTCAGCAGGCGCAGTCGGTGACCGTTGAAACAGGTACACCGCACCTCGCGCCCAGCAACAGCGGCGATACGCTGA
CCACGCAGATCGCCAACCCCAACTTTTGGCAGACCGGACCGCTTGCGTCCTCGCAAGTTTCGACGTTGCTCGCGTATGCA
CGAAGCAAGTCCTTCAAACGCGTCGCGATCATTGGTGACAACACGGGGCTGGGCCAGCTGATGACGCAATCTTTCAAGGC
TGGTATCGAAGCTGCAAAGATCCAAGTTGTCAGTGAGGAAGTGGTTCCACGTGGCGCCAATAGCGCTGATGCCCAGATTC
AGAGAGTTCGGGCGTCGAATCCGGACGCGATCTTTCTCACCGGAATCCTCGCTCCAGAGAACACACTGATTCTGCGCGCC
TATCGACTGCTGGGCCTCAAGGCGCCACTGCTCGGGAACTTTAGTTTCTCGAACATTCAGTACGCATCGGTCGCAAAGGG
GTTGTTGGACGGGTTGGTCTTCATCGATGCGTTCGATCCCACCAAGCCGCAAGTGCAGCGGTTCATCGCGACCTATACCA
AGGCCGCCGGAACTGCGCCCGACAACATCAATGCTTACGGTTACGACGGGGTGATGCTTGTGGCCGACGCGATTCGCCGT
GCGGGCGGAACGGACAAGCTCAAGGTCCGCGATGCGATGCAAGCAACCAAGGGGTTCGTAGGCGTGCTGGGAGCGCAGGG
AGCAAGCTATGGCTTCGCCAACGGAAAGCGCACGGGTTTCGATGGTGATGGCTTGGTGGTGCGCATCTACGAAGGTGATC
GCCAGGGCAAAGTGCAATTCACCGGAACCCGTTGA

Upstream 100 bases:

>100_bases
CTGCTGGAGTCAGGCAGCTCGGCCGTGACGACGGACGCGGCAACGCACATCGCACTTGCGGTCTGAACCTGAAGAACATC
AATACAACGGAGACATCACC

Downstream 100 bases:

>100_bases
ACAAGCGCAGCTCTCGCTATGCAAGACTTCTTCGAACTTCTGGTCAGCGCCGTATCGACCGGTTGCATCTACGGGCTTGT
TGCCTTGGCCTATCTGCTCA

Product: extracellular ligand-binding receptor

Products: ADP; phosphate; L-leucine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MHLSSTSRLASLLMAGLISVAAMPAASQPIKLGIITDRVGAAKPYAEPVLQGAQVAAKELNASGGVLGRPIELLVEDDQG
RPDLSATAARKLVDSGVAFILSISWTSATQQAQSVTVETGTPHLAPSNSGDTLTTQIANPNFWQTGPLASSQVSTLLAYA
RSKSFKRVAIIGDNTGLGQLMTQSFKAGIEAAKIQVVSEEVVPRGANSADAQIQRVRASNPDAIFLTGILAPENTLILRA
YRLLGLKAPLLGNFSFSNIQYASVAKGLLDGLVFIDAFDPTKPQVQRFIATYTKAAGTAPDNINAYGYDGVMLVADAIRR
AGGTDKLKVRDAMQATKGFVGVLGAQGASYGFANGKRTGFDGDGLVVRIYEGDRQGKVQFTGTR

Sequences:

>Translated_384_residues
MHLSSTSRLASLLMAGLISVAAMPAASQPIKLGIITDRVGAAKPYAEPVLQGAQVAAKELNASGGVLGRPIELLVEDDQG
RPDLSATAARKLVDSGVAFILSISWTSATQQAQSVTVETGTPHLAPSNSGDTLTTQIANPNFWQTGPLASSQVSTLLAYA
RSKSFKRVAIIGDNTGLGQLMTQSFKAGIEAAKIQVVSEEVVPRGANSADAQIQRVRASNPDAIFLTGILAPENTLILRA
YRLLGLKAPLLGNFSFSNIQYASVAKGLLDGLVFIDAFDPTKPQVQRFIATYTKAAGTAPDNINAYGYDGVMLVADAIRR
AGGTDKLKVRDAMQATKGFVGVLGAQGASYGFANGKRTGFDGDGLVVRIYEGDRQGKVQFTGTR
>Mature_384_residues
MHLSSTSRLASLLMAGLISVAAMPAASQPIKLGIITDRVGAAKPYAEPVLQGAQVAAKELNASGGVLGRPIELLVEDDQG
RPDLSATAARKLVDSGVAFILSISWTSATQQAQSVTVETGTPHLAPSNSGDTLTTQIANPNFWQTGPLASSQVSTLLAYA
RSKSFKRVAIIGDNTGLGQLMTQSFKAGIEAAKIQVVSEEVVPRGANSADAQIQRVRASNPDAIFLTGILAPENTLILRA
YRLLGLKAPLLGNFSFSNIQYASVAKGLLDGLVFIDAFDPTKPQVQRFIATYTKAAGTAPDNINAYGYDGVMLVADAIRR
AGGTDKLKVRDAMQATKGFVGVLGAQGASYGFANGKRTGFDGDGLVVRIYEGDRQGKVQFTGTR

Specific function: Component of an amino-acid transport system (Potential) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the leucine-binding protein family [H]

Homologues:

Organism=Escherichia coli, GI1789867, Length=269, Percent_Identity=28.996282527881, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI48994941, Length=264, Percent_Identity=28.030303030303, Blast_Score=90, Evalue=3e-19,

Paralogues:

None

Copy number: 240 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001828
- InterPro:   IPR000709 [H]

Pfam domain/function: PF01094 ANF_receptor [H]

EC number: NA

Molecular weight: Translated: 40270; Mature: 40270

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHLSSTSRLASLLMAGLISVAAMPAASQPIKLGIITDRVGAAKPYAEPVLQGAQVAAKEL
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHH
NASGGVLGRPIELLVEDDQGRPDLSATAARKLVDSGVAFILSISWTSATQQAQSVTVETG
CCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCEEEEEEEECCCHHHHHHEEEEECC
TPHLAPSNSGDTLTTQIANPNFWQTGPLASSQVSTLLAYARSKSFKRVAIIGDNTGLGQL
CCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCHHHH
MTQSFKAGIEAAKIQVVSEEVVPRGANSADAQIQRVRASNPDAIFLTGILAPENTLILRA
HHHHHHCCCCEEEEEEEHHHHCCCCCCCHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHH
YRLLGLKAPLLGNFSFSNIQYASVAKGLLDGLVFIDAFDPTKPQVQRFIATYTKAAGTAP
HHHHCCCCCCCCCCCCCCEEHHHHHHHHHHCEEEEECCCCCCHHHHHHHHHHHHHCCCCC
DNINAYGYDGVMLVADAIRRAGGTDKLKVRDAMQATKGFVGVLGAQGASYGFANGKRTGF
CCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHEEECCCCCCCCCCCCCCCCC
DGDGLVVRIYEGDRQGKVQFTGTR
CCCCEEEEEEECCCCCEEEEECCC
>Mature Secondary Structure
MHLSSTSRLASLLMAGLISVAAMPAASQPIKLGIITDRVGAAKPYAEPVLQGAQVAAKEL
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHH
NASGGVLGRPIELLVEDDQGRPDLSATAARKLVDSGVAFILSISWTSATQQAQSVTVETG
CCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCEEEEEEEECCCHHHHHHEEEEECC
TPHLAPSNSGDTLTTQIANPNFWQTGPLASSQVSTLLAYARSKSFKRVAIIGDNTGLGQL
CCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCHHHH
MTQSFKAGIEAAKIQVVSEEVVPRGANSADAQIQRVRASNPDAIFLTGILAPENTLILRA
HHHHHHCCCCEEEEEEEHHHHCCCCCCCHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHH
YRLLGLKAPLLGNFSFSNIQYASVAKGLLDGLVFIDAFDPTKPQVQRFIATYTKAAGTAP
HHHHCCCCCCCCCCCCCCEEHHHHHHHHHHCEEEEECCCCCCHHHHHHHHHHHHHCCCCC
DNINAYGYDGVMLVADAIRRAGGTDKLKVRDAMQATKGFVGVLGAQGASYGFANGKRTGF
CCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHEEECCCCCCCCCCCCCCCCC
DGDGLVVRIYEGDRQGKVQFTGTR
CCCCEEEEEEECCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-leucine [Periplasm]; H2O [C]

Specific reaction: ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11756688 [H]