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The map label for this gene is yafC [H]

Identifier: 121611523

GI number: 121611523

Start: 5107440

End: 5108384

Strand: Direct

Name: yafC [H]

Synonym: Veis_4614

Alternate gene names: 121611523

Gene position: 5107440-5108384 (Clockwise)

Preceding gene: 121611510

Following gene: 121611524

Centisome position: 91.75

GC content: 66.46

Gene sequence:

>945_bases
ATGAGTCACTGGACCGAGTACGAGTTCTTCGTGCGGGTGGTGGAGCTGGGCAGCCTGAGCAAGGCGGCCGAAGCCATGGG
CTTGTCGAACCCGTCGGCCAGCCGCCATCTCGCGGCCCTGGAACGCCGCCTCGGCGCGAGGCTGATCGAACGCAGCACGC
GCCGCCTGTTCGTGACGGACGTCGGCCAGGACTTCTACCGCTGTTGCAAGAGGGCCCTGGACGACATGCAGGAGGCCGTC
GAGGCGGTCAACGCGACCACGTCCAACCCGGTGGGTGTGCTGCGCGTGACCGCGTCGCTGTCGCTGTCGATGCAGCACAT
CGCGCCGCTGCTACCGGCATTCGCGCAGCGATACCCCAACATCCGCGTGAAAGTGGTCGCAGCCAATCGCTACTACGACA
TCATCGACAACAACATCGACGTGGCGCTGCGCACGCGCGAGTCCGAACCGGACTCGAGCCTCGTGATCCGAAGCCTGGCG
ACCACGCGGCGCGTGCTGGCCGTCTCACCGGCCTACCTCGAGCGCCACGGTGCGCCCCGCCACCCGCGGGAATTGGCGGA
GCACCGGTTGCTGCTGTACACGTACCACGCCCCCGACTCGCTGACCTTCCAGCGCGGCGACGAGGCCGTGACGATTCCAA
CCAAGCCCATGCTCGAAGCCAACGACGGCCAGGTCCTGCGCGTGGCGGGCGTGCAAGGGCTGGGGATCATGGTGCAACCG
ATGTACGTGATCTACGACGACCTGGTGGCGGATCGCCTGATTCCGGTCATGACCGACTGGAAGCTGCCGCCGATGTCGGT
CAACATCGTCTATCAGCACCGCCGCCTCGTCCCGGCGAAGACCCGCGCCTTCATCGACTTCCTGGTGGAAGACTTCCAGC
GGCAGGATTACGAAAGGCGTTGGGCTTCAATGATGGCGGGTCGCGCCGACCGGGTCGCCCCGTGA

Upstream 100 bases:

>100_bases
AAAGCGCATGCGAGGAGGTTCGAAGCGAATGCTATGGATGACTCGAATGGAAATATATGACGATAATGAAAATGACATTT
TCATTGGGCGGAAGAATCCC

Downstream 100 bases:

>100_bases
CCGTGTGGCCGTAGAGGGGCCTCTGACGAAGACGTCTAGTGTCGCGTCACCGATCATCTGTCGGTCTGCGCTGGCCATCG
AAGCGCATCGCGGCGTTGCA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MSHWTEYEFFVRVVELGSLSKAAEAMGLSNPSASRHLAALERRLGARLIERSTRRLFVTDVGQDFYRCCKRALDDMQEAV
EAVNATTSNPVGVLRVTASLSLSMQHIAPLLPAFAQRYPNIRVKVVAANRYYDIIDNNIDVALRTRESEPDSSLVIRSLA
TTRRVLAVSPAYLERHGAPRHPRELAEHRLLLYTYHAPDSLTFQRGDEAVTIPTKPMLEANDGQVLRVAGVQGLGIMVQP
MYVIYDDLVADRLIPVMTDWKLPPMSVNIVYQHRRLVPAKTRAFIDFLVEDFQRQDYERRWASMMAGRADRVAP

Sequences:

>Translated_314_residues
MSHWTEYEFFVRVVELGSLSKAAEAMGLSNPSASRHLAALERRLGARLIERSTRRLFVTDVGQDFYRCCKRALDDMQEAV
EAVNATTSNPVGVLRVTASLSLSMQHIAPLLPAFAQRYPNIRVKVVAANRYYDIIDNNIDVALRTRESEPDSSLVIRSLA
TTRRVLAVSPAYLERHGAPRHPRELAEHRLLLYTYHAPDSLTFQRGDEAVTIPTKPMLEANDGQVLRVAGVQGLGIMVQP
MYVIYDDLVADRLIPVMTDWKLPPMSVNIVYQHRRLVPAKTRAFIDFLVEDFQRQDYERRWASMMAGRADRVAP
>Mature_313_residues
SHWTEYEFFVRVVELGSLSKAAEAMGLSNPSASRHLAALERRLGARLIERSTRRLFVTDVGQDFYRCCKRALDDMQEAVE
AVNATTSNPVGVLRVTASLSLSMQHIAPLLPAFAQRYPNIRVKVVAANRYYDIIDNNIDVALRTRESEPDSSLVIRSLAT
TRRVLAVSPAYLERHGAPRHPRELAEHRLLLYTYHAPDSLTFQRGDEAVTIPTKPMLEANDGQVLRVAGVQGLGIMVQPM
YVIYDDLVADRLIPVMTDWKLPPMSVNIVYQHRRLVPAKTRAFIDFLVEDFQRQDYERRWASMMAGRADRVAP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=287, Percent_Identity=33.7979094076655, Blast_Score=154, Evalue=7e-39,
Organism=Escherichia coli, GI145693193, Length=284, Percent_Identity=29.5774647887324, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1789639, Length=286, Percent_Identity=28.6713286713287, Blast_Score=121, Evalue=7e-29,
Organism=Escherichia coli, GI1787128, Length=287, Percent_Identity=25.0871080139373, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1789440, Length=287, Percent_Identity=25.7839721254355, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI87081978, Length=287, Percent_Identity=27.5261324041812, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1787589, Length=282, Percent_Identity=23.0496453900709, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1789173, Length=245, Percent_Identity=26.1224489795918, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI157672245, Length=117, Percent_Identity=31.6239316239316, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788706, Length=289, Percent_Identity=25.6055363321799, Blast_Score=68, Evalue=8e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35590; Mature: 35459

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: PS50931 HTH_LYSR ; PS00237 G_PROTEIN_RECEP_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHWTEYEFFVRVVELGSLSKAAEAMGLSNPSASRHLAALERRLGARLIERSTRRLFVTD
CCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEC
VGQDFYRCCKRALDDMQEAVEAVNATTSNPVGVLRVTASLSLSMQHIAPLLPAFAQRYPN
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCC
IRVKVVAANRYYDIIDNNIDVALRTRESEPDSSLVIRSLATTRRVLAVSPAYLERHGAPR
EEEEEEEECCEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHHEEECHHHHHHCCCCC
HPRELAEHRLLLYTYHAPDSLTFQRGDEAVTIPTKPMLEANDGQVLRVAGVQGLGIMVQP
CHHHHHCCEEEEEEEECCCCCEEECCCCEEEECCCCCEECCCCCEEEEECCCCCCEEECH
MYVIYDDLVADRLIPVMTDWKLPPMSVNIVYQHRRLVPAKTRAFIDFLVEDFQRQDYERR
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
WASMMAGRADRVAP
HHHHHCCCCCCCCC
>Mature Secondary Structure 
SHWTEYEFFVRVVELGSLSKAAEAMGLSNPSASRHLAALERRLGARLIERSTRRLFVTD
CCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEC
VGQDFYRCCKRALDDMQEAVEAVNATTSNPVGVLRVTASLSLSMQHIAPLLPAFAQRYPN
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCC
IRVKVVAANRYYDIIDNNIDVALRTRESEPDSSLVIRSLATTRRVLAVSPAYLERHGAPR
EEEEEEEECCEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHHEEECHHHHHHCCCCC
HPRELAEHRLLLYTYHAPDSLTFQRGDEAVTIPTKPMLEANDGQVLRVAGVQGLGIMVQP
CHHHHHCCEEEEEEEECCCCCEEECCCCEEEECCCCCEECCCCCEEEEECCCCCCEEECH
MYVIYDDLVADRLIPVMTDWKLPPMSVNIVYQHRRLVPAKTRAFIDFLVEDFQRQDYERR
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
WASMMAGRADRVAP
HHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]