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The map label for this gene is dppA [H]

Identifier: 121611504

GI number: 121611504

Start: 5089588

End: 5090409

Strand: Direct

Name: dppA [H]

Synonym: Veis_4595

Alternate gene names: 121611504

Gene position: 5089588-5090409 (Clockwise)

Preceding gene: 121611503

Following gene: 121611508

Centisome position: 91.43

GC content: 67.52

Gene sequence:

>822_bases
ATGAAAGTCCTGATCTCCACCGACATCGAAGGCGTGGCGGGCGTCTACCACCACGAGCAGACACGCCAGGGCAACCCCGA
ATACGAACGCGCGCGCGTGCTGATGGCACACGAGGCCAACGCCGCGATTGCCGGCGCCTTCGACGCCGGCGCCACCGAGG
TGCTGGTGAACGACTCGCACGGCGGCTTTCGCAACATGCCGCCCGACATGCTCGACGCACGCGCCCGTGTCGTGCAGGGC
AAGCCGCGCTACCTGAGCATGGTGGCCGGCGTGGAAGAAGACGGTGTGCAGGCGCTCTGCATGCTCGGCTACCACTCGCG
CGCGCAAGGCCGCGGCATCCTCGCGCACACGATCAACGGCTTTGCCTTTGCGGGCATCCGCTTTGGCGATCAGGAACTGG
GCGAGGCCGGGATCTACGGCGCGCTGGCCGGCGCGTACGGCGTGCCCGTGGTGATGGGCAGCGGCGACGACATGTTCATC
GCCGAGAACCGCGCGCTCTTTCCGCACGCGACCTTCGTGCAGACCAAGAAGGCGACGGGCTTCAACAGCGGCGTGTCGCT
CTCGTCGGAGCAATCGCGCCAGGCGATCCGTGCCGGCGTGATCGAAGCGCTGGCCGCGCGTGCCAATGCACGTCCGCTGG
TCTTCAAGGGCCCGCAGGTGGTCACGCTGCGCACCCAGTCGCCGATGATGGCCGACCTGTTCTGCCAATGGCCGAGCTTC
GAGCGCGTCGACGGCGTCACGCTGCGTTTCAGTGCTGACACGGTGGAAGCAGCCGTGCGCGTGCTGAACTGCTGCTCGGC
GATGTCGTCGATGCTGCGCTGA

Upstream 100 bases:

>100_bases
GCCACGCCCGTCACGGGGCGCGACGGCAACCACCGCGCTGCGCTCGGCGAACTGCTGCCGGCGTCTTCCCTTTCACCTCT
CGTTTAGAAAACACACGCTC

Downstream 100 bases:

>100_bases
AGCCGCAGCTTCTCAGAAGGTGCGAATGAATCCGGCGTGGCCGAGCAGCCCGCCCAGGCGCGTCCCCTCAAGGCGCAAAG
CGCAGCCATAGCTCGGGCTA

Product: peptidase M55, D-aminopeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MKVLISTDIEGVAGVYHHEQTRQGNPEYERARVLMAHEANAAIAGAFDAGATEVLVNDSHGGFRNMPPDMLDARARVVQG
KPRYLSMVAGVEEDGVQALCMLGYHSRAQGRGILAHTINGFAFAGIRFGDQELGEAGIYGALAGAYGVPVVMGSGDDMFI
AENRALFPHATFVQTKKATGFNSGVSLSSEQSRQAIRAGVIEALAARANARPLVFKGPQVVTLRTQSPMMADLFCQWPSF
ERVDGVTLRFSADTVEAAVRVLNCCSAMSSMLR

Sequences:

>Translated_273_residues
MKVLISTDIEGVAGVYHHEQTRQGNPEYERARVLMAHEANAAIAGAFDAGATEVLVNDSHGGFRNMPPDMLDARARVVQG
KPRYLSMVAGVEEDGVQALCMLGYHSRAQGRGILAHTINGFAFAGIRFGDQELGEAGIYGALAGAYGVPVVMGSGDDMFI
AENRALFPHATFVQTKKATGFNSGVSLSSEQSRQAIRAGVIEALAARANARPLVFKGPQVVTLRTQSPMMADLFCQWPSF
ERVDGVTLRFSADTVEAAVRVLNCCSAMSSMLR
>Mature_273_residues
MKVLISTDIEGVAGVYHHEQTRQGNPEYERARVLMAHEANAAIAGAFDAGATEVLVNDSHGGFRNMPPDMLDARARVVQG
KPRYLSMVAGVEEDGVQALCMLGYHSRAQGRGILAHTINGFAFAGIRFGDQELGEAGIYGALAGAYGVPVVMGSGDDMFI
AENRALFPHATFVQTKKATGFNSGVSLSSEQSRQAIRAGVIEALAARANARPLVFKGPQVVTLRTQSPMMADLFCQWPSF
ERVDGVTLRFSADTVEAAVRVLNCCSAMSSMLR

Specific function: Hydrolyzes N-terminal residues in D-amino acid containing peptides. Among the tested substrates, the highest activities are with D-Ala-D-Ala and D-Ala-Gly-Gly. The physiological role is not clear [H]

COG id: COG2362

COG function: function code E; D-aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M55 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007035 [H]

Pfam domain/function: PF04951 Peptidase_M55 [H]

EC number: NA

Molecular weight: Translated: 29226; Mature: 29226

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLISTDIEGVAGVYHHEQTRQGNPEYERARVLMAHEANAAIAGAFDAGATEVLVNDSH
CEEEEECCCCHHHHHHHHHHHCCCCCCHHHHEEEEEECCCCEEEECCCCCCEEEEEECCC
GGFRNMPPDMLDARARVVQGKPRYLSMVAGVEEDGVQALCMLGYHSRAQGRGILAHTING
CCCCCCCHHHHHHHHHHHCCCCHHHHEECCCCCCCHHHEEECCCCCCCCCCEEEEEECCC
FAFAGIRFGDQELGEAGIYGALAGAYGVPVVMGSGDDMFIAENRALFPHATFVQTKKATG
EEEEEEEECCHHHCCCCHHHHHHHCCCCEEEEECCCCEEEECCCEECCCHHHEEECCCCC
FNSGVSLSSEQSRQAIRAGVIEALAARANARPLVFKGPQVVTLRTQSPMMADLFCQWPSF
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCEEEEEECCCCCHHHHHCCCCCC
ERVDGVTLRFSADTVEAAVRVLNCCSAMSSMLR
CCCCCEEEEEECHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKVLISTDIEGVAGVYHHEQTRQGNPEYERARVLMAHEANAAIAGAFDAGATEVLVNDSH
CEEEEECCCCHHHHHHHHHHHCCCCCCHHHHEEEEEECCCCEEEECCCCCCEEEEEECCC
GGFRNMPPDMLDARARVVQGKPRYLSMVAGVEEDGVQALCMLGYHSRAQGRGILAHTING
CCCCCCCHHHHHHHHHHHCCCCHHHHEECCCCCCCHHHEEECCCCCCCCCCEEEEEECCC
FAFAGIRFGDQELGEAGIYGALAGAYGVPVVMGSGDDMFIAENRALFPHATFVQTKKATG
EEEEEEEECCHHHCCCCHHHHHHHCCCCEEEEECCCCEEEECCCEECCCHHHEEECCCCC
FNSGVSLSSEQSRQAIRAGVIEALAARANARPLVFKGPQVVTLRTQSPMMADLFCQWPSF
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCEEEEEECCCCCHHHHHCCCCCC
ERVDGVTLRFSADTVEAAVRVLNCCSAMSSMLR
CCCCCEEEEEECHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1766370; 9384377 [H]