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The map label for this gene is quiP [H]

Identifier: 121611219

GI number: 121611219

Start: 4747211

End: 4749136

Strand: Direct

Name: quiP [H]

Synonym: Veis_4305

Alternate gene names: 121611219

Gene position: 4747211-4749136 (Clockwise)

Preceding gene: 121611218

Following gene: 121611224

Centisome position: 85.28

GC content: 70.04

Gene sequence:

>1926_bases
GTGGCAGTTGATGCCCCCTACCCCGGCGAGCAGCCCGCCGCCTCGGCGGACCTGGCGGCGCTGTATCGCCAATGGGGGGT
TTACCGGCGTTCTCCGGCCACCGACCCCAGCACCAGCACCTCCGCCGCCACCGGACCGCAAGCAGCCGCCCCGGCCCGGC
AAGACCCATGGCTTGGCCACGCCAACGATCTGAACGCCGGCCTGCTGGCCTGGGCCGAAGCGCTCACGCGCAATGCCGGC
AGCAATGAAGGCCGGGGCAGCAACAACTGGGCGCTGGCAGGCACGCGCACGGTCAGTGGCCGACCGCTGCTGGCCAACGA
CCCGCACCTGGGGCTGGCGGCGCCGGCGATCTGGTACTTTGCCGCGCTGCAAGCGCCTGCGGGGCAGGCCTCGGACGGCA
CGCCGATCGCCCCGTTGGCCGCAGTCGGGGCCACCTTGCCCGGCCTGCCTTTCGTGGTGCTGGGCCGCACCGACCATGTG
GCCTGGGGCTTTACCAACACCAGCCCCGACGTGCAGGACCTGTACCTGGAGCAGATCAACCCCGCCGATCCCACGCAATA
CCGCACCCCCGAGGGCTGGGCGCCGTTCACGGTGCGCACCGAAACCATCCGCGTCAAAGGGGCCGCCGATACCGTGCTCA
GGCTGCGCAGCACCCGCCATGGCCCGGTGCTGAGCGATGTGCAAAAGTCGCATGCCGAGGTGCTGGACCTGGACAAATAC
CTGATCGCGCTACGCTGGAGTGCGCTCGACGCCGACAACCAGAGCGTGATGGCGGGCCTGCAAACCAACCAGGCCCGGAC
GGTCGATGAATTGTTCCAGGCCATGTCACCGTATCACTCGCCGATGCAGAACGTGGTGGCGGCCGACGACCAGGGCCGGA
TCCGTTTCCAGGCCATGGGCCGGGTGCCGCTGCGCGATCCCGCCAACGACATCCGGGGCGTGGCCCCGGCGCCCGGCTGG
CAGGCGCGCTACGACTGGACGGGTTGGCTGCCTGCGGCGCAGACCCCGCGCGACGACGGCGCCAAGGGCTGGGTGGCCAC
GGCCAACCAGCGCGTGACGGCGCCGGACTACCCGCATTACCTGACGCAAGACTGGGTTCTGCCCTACCGCTATCAGCGCA
TAGAACAGCTCATCGAGGCCCGCGAAAAGCACGACATCGCCAGCATGCAGGCCATGCAGCATGATGTGACATCGCTGGCC
ACGCGCCGGCTGCTGCCCTCTCTGCGACAGGCCCGCTCGCCGCATCCGCTGGCCGCGCCCGTGCAAGCGCTGCTGGCGAA
CTTTGACGCCGTGATGGATGCCGACCAAGCGGCGCCCCTGGTGTTTGCCGCCTGGGCCGATGAGCTCACGCGCGGCCTGA
TCGAGCCGCGCATCGGCCAGGCGCGCTTTGCCGCCACCTATGGCAAGCGCGACTACCGGGCGGCGCTGGAAGGCATCCTG
GAACGCAACGACGGCTGGTGGTGCCAGCCCATGTCCTGCGCCGAGCAATCCTCTGCCGCGCTGACCCGTGCGCTGGAGCG
CCTGCAAACGGCCTATGGCCCCGACCCGGCACAGTGGCGCTGGGGCATTGCGCACCCGGCGCTGAGCGAGCACCAGCCGT
TTGGCAACGTGCCGGCGCTGGCCCGTTTTTTCAACGTCCGCGTCGCCTCGCATGGCGACTCGTACACCGTGAACGTGGGG
CAGTACAACCCGGGCCAGACCCGGGGGCCGTTCGTGAACCGCCATGCGGCCTCGCTGCGCGCGGTGTATGACTTGGCGGA
CCTGGAGCAGTCGCGCTTCATCTACCAGACCGGCCAGAGCGGGCTGGTGTTCTCGCCCCGCTACCGCGACATGAGCGCCG
CCTGGGCCGCCACCGGCTACCGCCCCCTGCAACGCCGGCCAGCGCATTGGGCGCATCGGCTGACCCTGGTGCCTGCTGCT
CCGTGA

Upstream 100 bases:

>100_bases
GCGTGGGCTGGACGCTGATGATGGCGCTGGACCTGGGCGGCAACTGGGGCCAGGAATTCGCGCGTCTGGCACTCGCCAGG
ACGCTGGACACGGACCGCCT

Downstream 100 bases:

>100_bases
GCCTGCGGGCCGCCGCCCATTGCGTAGCCCGTTCAGTAACGGATGCTGCCGGCGCAAGACCCGCAAGACCCAGATGCGCC
GACAGCGATGAAAACGAGAG

Product: penicillin amidase

Products: NA

Alternate protein names: AHL acylase quiP; Acyl-HSL acylase quiP; Quorum signal utilization and inactivation protein; Acyl-HSL acylase quiP subunit alpha; Acyl-HSL acylase quiP subunit beta [H]

Number of amino acids: Translated: 641; Mature: 640

Protein sequence:

>641_residues
MAVDAPYPGEQPAASADLAALYRQWGVYRRSPATDPSTSTSAATGPQAAAPARQDPWLGHANDLNAGLLAWAEALTRNAG
SNEGRGSNNWALAGTRTVSGRPLLANDPHLGLAAPAIWYFAALQAPAGQASDGTPIAPLAAVGATLPGLPFVVLGRTDHV
AWGFTNTSPDVQDLYLEQINPADPTQYRTPEGWAPFTVRTETIRVKGAADTVLRLRSTRHGPVLSDVQKSHAEVLDLDKY
LIALRWSALDADNQSVMAGLQTNQARTVDELFQAMSPYHSPMQNVVAADDQGRIRFQAMGRVPLRDPANDIRGVAPAPGW
QARYDWTGWLPAAQTPRDDGAKGWVATANQRVTAPDYPHYLTQDWVLPYRYQRIEQLIEAREKHDIASMQAMQHDVTSLA
TRRLLPSLRQARSPHPLAAPVQALLANFDAVMDADQAAPLVFAAWADELTRGLIEPRIGQARFAATYGKRDYRAALEGIL
ERNDGWWCQPMSCAEQSSAALTRALERLQTAYGPDPAQWRWGIAHPALSEHQPFGNVPALARFFNVRVASHGDSYTVNVG
QYNPGQTRGPFVNRHAASLRAVYDLADLEQSRFIYQTGQSGLVFSPRYRDMSAAWAATGYRPLQRRPAHWAHRLTLVPAA
P

Sequences:

>Translated_641_residues
MAVDAPYPGEQPAASADLAALYRQWGVYRRSPATDPSTSTSAATGPQAAAPARQDPWLGHANDLNAGLLAWAEALTRNAG
SNEGRGSNNWALAGTRTVSGRPLLANDPHLGLAAPAIWYFAALQAPAGQASDGTPIAPLAAVGATLPGLPFVVLGRTDHV
AWGFTNTSPDVQDLYLEQINPADPTQYRTPEGWAPFTVRTETIRVKGAADTVLRLRSTRHGPVLSDVQKSHAEVLDLDKY
LIALRWSALDADNQSVMAGLQTNQARTVDELFQAMSPYHSPMQNVVAADDQGRIRFQAMGRVPLRDPANDIRGVAPAPGW
QARYDWTGWLPAAQTPRDDGAKGWVATANQRVTAPDYPHYLTQDWVLPYRYQRIEQLIEAREKHDIASMQAMQHDVTSLA
TRRLLPSLRQARSPHPLAAPVQALLANFDAVMDADQAAPLVFAAWADELTRGLIEPRIGQARFAATYGKRDYRAALEGIL
ERNDGWWCQPMSCAEQSSAALTRALERLQTAYGPDPAQWRWGIAHPALSEHQPFGNVPALARFFNVRVASHGDSYTVNVG
QYNPGQTRGPFVNRHAASLRAVYDLADLEQSRFIYQTGQSGLVFSPRYRDMSAAWAATGYRPLQRRPAHWAHRLTLVPAA
P
>Mature_640_residues
AVDAPYPGEQPAASADLAALYRQWGVYRRSPATDPSTSTSAATGPQAAAPARQDPWLGHANDLNAGLLAWAEALTRNAGS
NEGRGSNNWALAGTRTVSGRPLLANDPHLGLAAPAIWYFAALQAPAGQASDGTPIAPLAAVGATLPGLPFVVLGRTDHVA
WGFTNTSPDVQDLYLEQINPADPTQYRTPEGWAPFTVRTETIRVKGAADTVLRLRSTRHGPVLSDVQKSHAEVLDLDKYL
IALRWSALDADNQSVMAGLQTNQARTVDELFQAMSPYHSPMQNVVAADDQGRIRFQAMGRVPLRDPANDIRGVAPAPGWQ
ARYDWTGWLPAAQTPRDDGAKGWVATANQRVTAPDYPHYLTQDWVLPYRYQRIEQLIEAREKHDIASMQAMQHDVTSLAT
RRLLPSLRQARSPHPLAAPVQALLANFDAVMDADQAAPLVFAAWADELTRGLIEPRIGQARFAATYGKRDYRAALEGILE
RNDGWWCQPMSCAEQSSAALTRALERLQTAYGPDPAQWRWGIAHPALSEHQPFGNVPALARFFNVRVASHGDSYTVNVGQ
YNPGQTRGPFVNRHAASLRAVYDLADLEQSRFIYQTGQSGLVFSPRYRDMSAAWAATGYRPLQRRPAHWAHRLTLVPAAP

Specific function: Catalyzes the deacylation of acyl-homoserine lactone (AHL or acyl-HSL), releasing homoserine lactone (HSL) and the corresponding fatty acid. Possesses a specificity for the degradation of long-chain acyl-HSLs (side chains of seven or more carbons in lengt

COG id: COG2366

COG function: function code R; Protein related to penicillin acylase

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S45 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014395
- InterPro:   IPR002692 [H]

Pfam domain/function: PF01804 Penicil_amidase [H]

EC number: =3.5.1.97 [H]

Molecular weight: Translated: 70130; Mature: 69999

Theoretical pI: Translated: 7.87; Mature: 7.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVDAPYPGEQPAASADLAALYRQWGVYRRSPATDPSTSTSAATGPQAAAPARQDPWLGH
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
ANDLNAGLLAWAEALTRNAGSNEGRGSNNWALAGTRTVSGRPLLANDPHLGLAAPAIWYF
CCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCEECCCCCCCHHHHHHHHH
AALQAPAGQASDGTPIAPLAAVGATLPGLPFVVLGRTDHVAWGFTNTSPDVQDLYLEQIN
HHHCCCCCCCCCCCCCHHHHHHHCCCCCCCEEEEECCCCEEEECCCCCCCHHHHHHHHCC
PADPTQYRTPEGWAPFTVRTETIRVKGAADTVLRLRSTRHGPVLSDVQKSHAEVLDLDKY
CCCCCCCCCCCCCCCEEEEEEEEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
LIALRWSALDADNQSVMAGLQTNQARTVDELFQAMSPYHSPMQNVVAADDQGRIRFQAMG
HHHHHHHHCCCCCHHHHCCCCCCCHHHHHHHHHHHCHHHHHHHHHHCCCCCCCEEEEEEC
RVPLRDPANDIRGVAPAPGWQARYDWTGWLPAAQTPRDDGAKGWVATANQRVTAPDYPHY
CCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCH
LTQDWVLPYRYQRIEQLIEAREKHDIASMQAMQHDVTSLATRRLLPSLRQARSPHPLAAP
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
VQALLANFDAVMDADQAAPLVFAAWADELTRGLIEPRIGQARFAATYGKRDYRAALEGIL
HHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHCCCCCCCHHHHHHHCCHHHHHHHHHHH
ERNDGWWCQPMSCAEQSSAALTRALERLQTAYGPDPAQWRWGIAHPALSEHQPFGNVPAL
HCCCCCEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCHHHH
ARFFNVRVASHGDSYTVNVGQYNPGQTRGPFVNRHAASLRAVYDLADLEQSRFIYQTGQS
HHHHHEEEECCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCEEEECCCC
GLVFSPRYRDMSAAWAATGYRPLQRRPAHWAHRLTLVPAAP
CCEECCCCCCCHHHHHHCCCCHHHCCCCCHHHEEEEECCCC
>Mature Secondary Structure 
AVDAPYPGEQPAASADLAALYRQWGVYRRSPATDPSTSTSAATGPQAAAPARQDPWLGH
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
ANDLNAGLLAWAEALTRNAGSNEGRGSNNWALAGTRTVSGRPLLANDPHLGLAAPAIWYF
CCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCEECCCCCCCHHHHHHHHH
AALQAPAGQASDGTPIAPLAAVGATLPGLPFVVLGRTDHVAWGFTNTSPDVQDLYLEQIN
HHHCCCCCCCCCCCCCHHHHHHHCCCCCCCEEEEECCCCEEEECCCCCCCHHHHHHHHCC
PADPTQYRTPEGWAPFTVRTETIRVKGAADTVLRLRSTRHGPVLSDVQKSHAEVLDLDKY
CCCCCCCCCCCCCCCEEEEEEEEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
LIALRWSALDADNQSVMAGLQTNQARTVDELFQAMSPYHSPMQNVVAADDQGRIRFQAMG
HHHHHHHHCCCCCHHHHCCCCCCCHHHHHHHHHHHCHHHHHHHHHHCCCCCCCEEEEEEC
RVPLRDPANDIRGVAPAPGWQARYDWTGWLPAAQTPRDDGAKGWVATANQRVTAPDYPHY
CCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCH
LTQDWVLPYRYQRIEQLIEAREKHDIASMQAMQHDVTSLATRRLLPSLRQARSPHPLAAP
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
VQALLANFDAVMDADQAAPLVFAAWADELTRGLIEPRIGQARFAATYGKRDYRAALEGIL
HHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHCCCCCCCHHHHHHHCCHHHHHHHHHHH
ERNDGWWCQPMSCAEQSSAALTRALERLQTAYGPDPAQWRWGIAHPALSEHQPFGNVPAL
HCCCCCEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCHHHH
ARFFNVRVASHGDSYTVNVGQYNPGQTRGPFVNRHAASLRAVYDLADLEQSRFIYQTGQS
HHHHHEEEECCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCEEEECCCC
GLVFSPRYRDMSAAWAATGYRPLQRRPAHWAHRLTLVPAAP
CCEECCCCCCCHHHHHHCCCCHHHCCCCCHHHEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]