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The map label for this gene is glnS [H]

Identifier: 121611150

GI number: 121611150

Start: 4664079

End: 4665965

Strand: Direct

Name: glnS [H]

Synonym: Veis_4234

Alternate gene names: 121611150

Gene position: 4664079-4665965 (Clockwise)

Preceding gene: 121611143

Following gene: 121611151

Centisome position: 83.78

GC content: 65.55

Gene sequence:

>1887_bases
ATGAGCGCCCACATCCCCTCCGCATCCCCGGCCCACACCCCCGCCCTCCCCAAAGCCAGCAACTTCCTGCGCCAGCTCAT
CGAATCCGACCTGGCAAAAGGCACCTACGCCAGCCGCCGCTGGGCCGGCAGCCCCGGCGACGCCGCCCACCACGCCCAGG
GCGGCCCCGACCCCGCCAAAATACGCACCCGCTTCCCGCCCGAGCCGAATGGCTACCTGCACATCGGCCACGCCAAAAGC
ATCTGCCTGAACTTCGGCTTGGCGCGCGACTACGGCGGTGTGTGCCACCTGCGCTTTGACGACACCAATCCGGAAAAAGA
AAACCCCGAATACGTCGACAGCATCATCGACGCGGTGCAATGGCTCGGCTTTGACTGGCGCCAGGGCGGCAACGGCCAGC
CCTACCAGGCCAGCGACTACTTCGACTTCATGTACCGCGCCGCCGAGCACCTGGTCGAAACCGGCCACGCCTACGTGGAC
GAACAAACGGTGGAACAAATCCGCATCCACCGTGGCGACTTCAGCAAGCCCGGCGTGGACAGCCCCTTTCGCAACCGCAG
CCCGGCAGAAAACCTGGCCCGCTTGCGCGAAATGCGTGCCGGCCAGCACGAAGACGGATCGATGGTGCTGCGCGCCAGGA
TCGACATGGCCCACCCCAACATCAACATGCGCGATCCGACCATCTACCGCATCCGCCGCACCACCCACCACCGCACGGGC
GACACCTGGTGCATCTACCCCCTGTACACCTACGCGCACCCGATCGAGGACGCGCTGGAGCAAATCACCCACAGCCTGTG
CACGCTCGAATTTGAAGACCAGCGCCCCTTCTACGACTGGCTGCTGGAGCGCTTGATCGAAACCACCCGGCTCCCCGACG
GGCGGGTCGTGGGCGGCCTGCTGGCCAGCCCGCCCCCGCGCCAGTACGAATTTGCGCGCCTGAACCTGACCTACGTGGTC
ACCAGCAAGCGCAAACTGGCCCAACTGGTGTACGACCACAAGGTCGACGGCTGGGACGACCCCCGCATGCCCACCCTCGC
GGGCCTGCGCCGCCGTGGCTACACCCCCGCCGCGCTGCAACTGTTTGCCGAACGCATAGGCGTGACCAAAAGCGACAGTT
GGATCGACTACAGCACCCTGGAAGGCTGCCTGCGCGAAGACCTGGAGCCCAAAGCCCACCGTGGCATGGCCGTGCTCAAT
CCCGTCAAGCTGGTGCTGACCAACTGGGATGCGGTCATGGGCGCCGGCCATTTGGAGCCCGGCACCCTGCCCGCGCTACC
CCACCCGATCGAAGGCCAGGCCAGCCCCCTGCGCCACTTTTGCATCGGCCAGCAACTGTGGATCGAGCGCGAAGACTTCG
AAGAACATCCCCCCAAGGGCTACAAGCGCCTATATCCACCCCGGCCCGGCGCCGACGGTCAAATGCTGCCCGGCAGCACC
GTGCGCCTGAAGGGCGGCTACGTCATCGAATGCACCGGCTGCACCAAGGACGCCACCGGCACCATCGTCCAAGTGCAGGC
CACCGTGGTGCCCGACACCAAGAGCGGCACCCCCGGCGCCAACAGCGTCAAGGTCAAAGCCGCCATCACCTGGGTCGGCG
TGGCCGACGGCGTGCGCGCCGAGGTGCGCATGTACGACCGCCTGTTCCTGGACGCGCACCCTGACGCCGGCAGCAAAGAC
TTCATCGAAAGCCTGAACCCCGACAGCCTGAAGGTAGTGAGCGCCATCGTCGAGCCCTCACTGGCCCATGCCAAGCCGGA
CGACAAGTTCCAATTCGAGCGCCATGGGTACTTTGTCGCAGACCGGGTCGATCATGTGCCAGGCCGGCCGGTATTCAATC
TGGCGGTCGGATTGAAGGATTCCTGGGGGAAATCAAGTGATTACTGA

Upstream 100 bases:

>100_bases
CCAGAACGATGCGGTCGGAAACATTCGTCTGCATGGCCGTTCTCATTTGGCAAAGGATGCGGCCATCATAGTGTGCTTGC
CCCGGCCTAAAATCGGCCCC

Downstream 100 bases:

>100_bases
GCTGCGCATGGAAAACTGGAAAAGCTACGCGCAATCTTCCCTGTATATCGATCCGTTGACCGTGTTGAGAGGCAGTGCTC
ACACGATATGCGGGCAAACT

Product: glutaminyl-tRNA synthetase

Products: NA

Alternate protein names: Glutamine--tRNA ligase; GlnRS [H]

Number of amino acids: Translated: 628; Mature: 627

Protein sequence:

>628_residues
MSAHIPSASPAHTPALPKASNFLRQLIESDLAKGTYASRRWAGSPGDAAHHAQGGPDPAKIRTRFPPEPNGYLHIGHAKS
ICLNFGLARDYGGVCHLRFDDTNPEKENPEYVDSIIDAVQWLGFDWRQGGNGQPYQASDYFDFMYRAAEHLVETGHAYVD
EQTVEQIRIHRGDFSKPGVDSPFRNRSPAENLARLREMRAGQHEDGSMVLRARIDMAHPNINMRDPTIYRIRRTTHHRTG
DTWCIYPLYTYAHPIEDALEQITHSLCTLEFEDQRPFYDWLLERLIETTRLPDGRVVGGLLASPPPRQYEFARLNLTYVV
TSKRKLAQLVYDHKVDGWDDPRMPTLAGLRRRGYTPAALQLFAERIGVTKSDSWIDYSTLEGCLREDLEPKAHRGMAVLN
PVKLVLTNWDAVMGAGHLEPGTLPALPHPIEGQASPLRHFCIGQQLWIEREDFEEHPPKGYKRLYPPRPGADGQMLPGST
VRLKGGYVIECTGCTKDATGTIVQVQATVVPDTKSGTPGANSVKVKAAITWVGVADGVRAEVRMYDRLFLDAHPDAGSKD
FIESLNPDSLKVVSAIVEPSLAHAKPDDKFQFERHGYFVADRVDHVPGRPVFNLAVGLKDSWGKSSDY

Sequences:

>Translated_628_residues
MSAHIPSASPAHTPALPKASNFLRQLIESDLAKGTYASRRWAGSPGDAAHHAQGGPDPAKIRTRFPPEPNGYLHIGHAKS
ICLNFGLARDYGGVCHLRFDDTNPEKENPEYVDSIIDAVQWLGFDWRQGGNGQPYQASDYFDFMYRAAEHLVETGHAYVD
EQTVEQIRIHRGDFSKPGVDSPFRNRSPAENLARLREMRAGQHEDGSMVLRARIDMAHPNINMRDPTIYRIRRTTHHRTG
DTWCIYPLYTYAHPIEDALEQITHSLCTLEFEDQRPFYDWLLERLIETTRLPDGRVVGGLLASPPPRQYEFARLNLTYVV
TSKRKLAQLVYDHKVDGWDDPRMPTLAGLRRRGYTPAALQLFAERIGVTKSDSWIDYSTLEGCLREDLEPKAHRGMAVLN
PVKLVLTNWDAVMGAGHLEPGTLPALPHPIEGQASPLRHFCIGQQLWIEREDFEEHPPKGYKRLYPPRPGADGQMLPGST
VRLKGGYVIECTGCTKDATGTIVQVQATVVPDTKSGTPGANSVKVKAAITWVGVADGVRAEVRMYDRLFLDAHPDAGSKD
FIESLNPDSLKVVSAIVEPSLAHAKPDDKFQFERHGYFVADRVDHVPGRPVFNLAVGLKDSWGKSSDY
>Mature_627_residues
SAHIPSASPAHTPALPKASNFLRQLIESDLAKGTYASRRWAGSPGDAAHHAQGGPDPAKIRTRFPPEPNGYLHIGHAKSI
CLNFGLARDYGGVCHLRFDDTNPEKENPEYVDSIIDAVQWLGFDWRQGGNGQPYQASDYFDFMYRAAEHLVETGHAYVDE
QTVEQIRIHRGDFSKPGVDSPFRNRSPAENLARLREMRAGQHEDGSMVLRARIDMAHPNINMRDPTIYRIRRTTHHRTGD
TWCIYPLYTYAHPIEDALEQITHSLCTLEFEDQRPFYDWLLERLIETTRLPDGRVVGGLLASPPPRQYEFARLNLTYVVT
SKRKLAQLVYDHKVDGWDDPRMPTLAGLRRRGYTPAALQLFAERIGVTKSDSWIDYSTLEGCLREDLEPKAHRGMAVLNP
VKLVLTNWDAVMGAGHLEPGTLPALPHPIEGQASPLRHFCIGQQLWIEREDFEEHPPKGYKRLYPPRPGADGQMLPGSTV
RLKGGYVIECTGCTKDATGTIVQVQATVVPDTKSGTPGANSVKVKAAITWVGVADGVRAEVRMYDRLFLDAHPDAGSKDF
IESLNPDSLKVVSAIVEPSLAHAKPDDKFQFERHGYFVADRVDHVPGRPVFNLAVGLKDSWGKSSDY

Specific function: Unknown

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI4826960, Length=573, Percent_Identity=40.4886561954625, Blast_Score=367, Evalue=1e-101,
Organism=Homo sapiens, GI62241042, Length=552, Percent_Identity=30.2536231884058, Blast_Score=231, Evalue=1e-60,
Organism=Homo sapiens, GI134288884, Length=102, Percent_Identity=35.2941176470588, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1786895, Length=612, Percent_Identity=48.0392156862745, Blast_Score=551, Evalue=1e-158,
Organism=Escherichia coli, GI1788743, Length=99, Percent_Identity=38.3838383838384, Blast_Score=84, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17543332, Length=579, Percent_Identity=37.8238341968912, Blast_Score=353, Evalue=1e-97,
Organism=Caenorhabditis elegans, GI17511007, Length=559, Percent_Identity=28.6225402504472, Blast_Score=214, Evalue=8e-56,
Organism=Caenorhabditis elegans, GI71993394, Length=218, Percent_Identity=26.1467889908257, Blast_Score=68, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6324742, Length=604, Percent_Identity=36.2582781456954, Blast_Score=330, Evalue=3e-91,
Organism=Saccharomyces cerevisiae, GI6321192, Length=557, Percent_Identity=34.1113105924596, Blast_Score=257, Evalue=3e-69,
Organism=Drosophila melanogaster, GI17864488, Length=573, Percent_Identity=37.521815008726, Blast_Score=347, Evalue=1e-95,
Organism=Drosophila melanogaster, GI24649466, Length=550, Percent_Identity=30.7272727272727, Blast_Score=229, Evalue=4e-60,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 1200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR004514
- InterPro:   IPR022861
- InterPro:   IPR000924
- InterPro:   IPR020061
- InterPro:   IPR020058
- InterPro:   IPR020059
- InterPro:   IPR020056
- InterPro:   IPR011035
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c; PF03950 tRNA-synt_1c_C [H]

EC number: =6.1.1.18 [H]

Molecular weight: Translated: 70245; Mature: 70114

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAHIPSASPAHTPALPKASNFLRQLIESDLAKGTYASRRWAGSPGDAAHHAQGGPDPAK
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCCCCCCCCCHHH
IRTRFPPEPNGYLHIGHAKSICLNFGLARDYGGVCHLRFDDTNPEKENPEYVDSIIDAVQ
EEECCCCCCCCEEEECCHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHH
WLGFDWRQGGNGQPYQASDYFDFMYRAAEHLVETGHAYVDEQTVEQIRIHRGDFSKPGVD
HCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHCCHHHHHHHHHHCCCCCCCCCC
SPFRNRSPAENLARLREMRAGQHEDGSMVLRARIDMAHPNINMRDPTIYRIRRTTHHRTG
CCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCCCCCCCEEEEEHHHCCCCC
DTWCIYPLYTYAHPIEDALEQITHSLCTLEFEDQRPFYDWLLERLIETTRLPDGRVVGGL
CCEEEEEHHHHHCCHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHCCCCCCEECHH
LASPPPRQYEFARLNLTYVVTSKRKLAQLVYDHKVDGWDDPRMPTLAGLRRRGYTPAALQ
HCCCCCCCEEEEEEEEEEEEECHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCHHHHH
LFAERIGVTKSDSWIDYSTLEGCLREDLEPKAHRGMAVLNPVKLVLTNWDAVMGAGHLEP
HHHHHHCCCCCCCCCCHHHHHHHHHHCCCCHHHCCEEEECCEEEEEECCHHHHCCCCCCC
GTLPALPHPIEGQASPLRHFCIGQQLWIEREDFEEHPPKGYKRLYPPRPGADGQMLPGST
CCCCCCCCCCCCCCCHHHHHHCCHHHCCCHHHHHHCCCCCHHCCCCCCCCCCCCCCCCCE
VRLKGGYVIECTGCTKDATGTIVQVQATVVPDTKSGTPGANSVKVKAAITWVGVADGVRA
EEECCCEEEEECCCCCCCCCCEEEEEEEEECCCCCCCCCCCCEEEEEEEEEEECCCCCHH
EVRMYDRLFLDAHPDAGSKDFIESLNPDSLKVVSAIVEPSLAHAKPDDKFQFERHGYFVA
HHHHHHHHEEECCCCCCCHHHHHCCCCCHHHHHHHHHCCHHHCCCCCCCCCHHHCCEEEE
DRVDHVPGRPVFNLAVGLKDSWGKSSDY
HHHCCCCCCCEEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
SAHIPSASPAHTPALPKASNFLRQLIESDLAKGTYASRRWAGSPGDAAHHAQGGPDPAK
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCCCCCCCCCHHH
IRTRFPPEPNGYLHIGHAKSICLNFGLARDYGGVCHLRFDDTNPEKENPEYVDSIIDAVQ
EEECCCCCCCCEEEECCHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHH
WLGFDWRQGGNGQPYQASDYFDFMYRAAEHLVETGHAYVDEQTVEQIRIHRGDFSKPGVD
HCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHCCHHHHHHHHHHCCCCCCCCCC
SPFRNRSPAENLARLREMRAGQHEDGSMVLRARIDMAHPNINMRDPTIYRIRRTTHHRTG
CCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCCCCCCCEEEEEHHHCCCCC
DTWCIYPLYTYAHPIEDALEQITHSLCTLEFEDQRPFYDWLLERLIETTRLPDGRVVGGL
CCEEEEEHHHHHCCHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHCCCCCCEECHH
LASPPPRQYEFARLNLTYVVTSKRKLAQLVYDHKVDGWDDPRMPTLAGLRRRGYTPAALQ
HCCCCCCCEEEEEEEEEEEEECHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCHHHHH
LFAERIGVTKSDSWIDYSTLEGCLREDLEPKAHRGMAVLNPVKLVLTNWDAVMGAGHLEP
HHHHHHCCCCCCCCCCHHHHHHHHHHCCCCHHHCCEEEECCEEEEEECCHHHHCCCCCCC
GTLPALPHPIEGQASPLRHFCIGQQLWIEREDFEEHPPKGYKRLYPPRPGADGQMLPGST
CCCCCCCCCCCCCCCHHHHHHCCHHHCCCHHHHHHCCCCCHHCCCCCCCCCCCCCCCCCE
VRLKGGYVIECTGCTKDATGTIVQVQATVVPDTKSGTPGANSVKVKAAITWVGVADGVRA
EEECCCEEEEECCCCCCCCCCEEEEEEEEECCCCCCCCCCCCEEEEEEEEEEECCCCCHH
EVRMYDRLFLDAHPDAGSKDFIESLNPDSLKVVSAIVEPSLAHAKPDDKFQFERHGYFVA
HHHHHHHHEEECCCCCCCHHHHHCCCCCHHHHHHHHHCCHHHCCCCCCCCCHHHCCEEEE
DRVDHVPGRPVFNLAVGLKDSWGKSSDY
HHHCCCCCCCEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12910271 [H]