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The map label for this gene is dch [H]

Identifier: 121611108

GI number: 121611108

Start: 4617107

End: 4617964

Strand: Direct

Name: dch [H]

Synonym: Veis_4192

Alternate gene names: 121611108

Gene position: 4617107-4617964 (Clockwise)

Preceding gene: 121611107

Following gene: 121611109

Centisome position: 82.94

GC content: 71.33

Gene sequence:

>858_bases
ATGGACACAGCAACCCCCACCGTCCCCCAAGATGCCCCCGTGCGCTGCGTGTCGCGCGGCGCCGTCTTCCAGATCGAACT
GAACCACCCCGAAGCGCGCAATCCGCTCGGCCCCGAGATGATCGATGCGCTCGATGCCGCGCTCACGCAGGCCATCGAGA
TGCCGGCCGCACGCGTCGTGCTGATCACGGCCGCAGGCGAGGCCTTCAGCGCAGGCGGCAACCTCGGCAACATGGCCGAG
CGCCTGAACGCGCCGCCCGGCGCCAACGGCAAGGACCCGATCGCCCAAGGCAACCGGCGCTATGGCGACTTCCTGCGCAG
GCTCTGCAGTGCGCCGAAGGTGGTGGTGGCCAGCGTGCGCGGTGCCGCGATGGGCGGCGGTGCGGGGCTGGTGTGCGCAG
CCGACATCGCCATCGGCGCGCAGGGTGCGAAGTTCGGTTTTCCCGAAGCGGCCATCGGCCTCGTGCCCGGGCAGATCCTG
CCCTTCGTCGCAGCGCGCATCGGCGCACAGGCCGCGCGCCGCCTCATGCTCACGGGCGAGCGCATCGATGCTGCCGAAGC
GCATCGCATCGGCCTGCTCGACTACCACGTGGCCGATCCCGAGCAACTGGCTGCGCGCACCGACGAACTGCTGGCACGCA
TCGTCGCCTGCGCGCCCGGCGCTTCGGCCGCCACCAAGCAGATGCTCCACACGGTGCTCGGCGCCAAGCGCTGGTGGAGC
GACGAGTTGCCCGGCTACCTCGACGAGGCCGCCGACACCTTCGCGCGGCAGATGCGCAGCGAGGCCATCGAAGGCGTCGC
CGCTGCGCGCGGCAAGCGGGCGCCGAACTGGCAGCAGGTCATCGCCGCGCGCGATTGA

Upstream 100 bases:

>100_bases
TGCCGCGCTGATGCAGGCGCGCGTGCTCGCCTCGTCGCCCACGCCGCACTGACGCACTGACGCACTGACCACGCCACTCC
CTCCCCTCCTGAAGCACACC

Downstream 100 bases:

>100_bases
AGAGAACACATTTTAAGGGGGCGGCATGACCATCGATGCCGTCATCGTTTCCACCGCACGAACGCCCATCGGCAAGGCCT
ACCGCGGCGCCTTCAACGAC

Product: enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: Cyclohexa-1,5-diene-1-carboxyl-CoA hydratase; Dienoyl-CoA hydratase [H]

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MDTATPTVPQDAPVRCVSRGAVFQIELNHPEARNPLGPEMIDALDAALTQAIEMPAARVVLITAAGEAFSAGGNLGNMAE
RLNAPPGANGKDPIAQGNRRYGDFLRRLCSAPKVVVASVRGAAMGGGAGLVCAADIAIGAQGAKFGFPEAAIGLVPGQIL
PFVAARIGAQAARRLMLTGERIDAAEAHRIGLLDYHVADPEQLAARTDELLARIVACAPGASAATKQMLHTVLGAKRWWS
DELPGYLDEAADTFARQMRSEAIEGVAAARGKRAPNWQQVIAARD

Sequences:

>Translated_285_residues
MDTATPTVPQDAPVRCVSRGAVFQIELNHPEARNPLGPEMIDALDAALTQAIEMPAARVVLITAAGEAFSAGGNLGNMAE
RLNAPPGANGKDPIAQGNRRYGDFLRRLCSAPKVVVASVRGAAMGGGAGLVCAADIAIGAQGAKFGFPEAAIGLVPGQIL
PFVAARIGAQAARRLMLTGERIDAAEAHRIGLLDYHVADPEQLAARTDELLARIVACAPGASAATKQMLHTVLGAKRWWS
DELPGYLDEAADTFARQMRSEAIEGVAAARGKRAPNWQQVIAARD
>Mature_285_residues
MDTATPTVPQDAPVRCVSRGAVFQIELNHPEARNPLGPEMIDALDAALTQAIEMPAARVVLITAAGEAFSAGGNLGNMAE
RLNAPPGANGKDPIAQGNRRYGDFLRRLCSAPKVVVASVRGAAMGGGAGLVCAADIAIGAQGAKFGFPEAAIGLVPGQIL
PFVAARIGAQAARRLMLTGERIDAAEAHRIGLLDYHVADPEQLAARTDELLARIVACAPGASAATKQMLHTVLGAKRWWS
DELPGYLDEAADTFARQMRSEAIEGVAAARGKRAPNWQQVIAARD

Specific function: Catalyzes the hydration of cyclohexa-1,5-diene-1- carboxyl-CoA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=291, Percent_Identity=27.8350515463918, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI37594471, Length=255, Percent_Identity=29.0196078431373, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI37594469, Length=255, Percent_Identity=29.0196078431373, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI70995211, Length=221, Percent_Identity=31.6742081447964, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI31542718, Length=267, Percent_Identity=26.9662921348315, Blast_Score=72, Evalue=8e-13,
Organism=Escherichia coli, GI221142681, Length=287, Percent_Identity=30.6620209059233, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787660, Length=267, Percent_Identity=33.3333333333333, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1787659, Length=268, Percent_Identity=29.1044776119403, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI87082183, Length=275, Percent_Identity=27.6363636363636, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788597, Length=193, Percent_Identity=30.5699481865285, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI25145438, Length=257, Percent_Identity=29.9610894941634, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17536985, Length=225, Percent_Identity=27.1111111111111, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17554946, Length=258, Percent_Identity=27.5193798449612, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI19920382, Length=220, Percent_Identity=29.0909090909091, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI20129971, Length=172, Percent_Identity=32.5581395348837, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24653477, Length=172, Percent_Identity=32.5581395348837, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI19922422, Length=265, Percent_Identity=26.7924528301887, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR017602 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.100 [H]

Molecular weight: Translated: 29755; Mature: 29755

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTATPTVPQDAPVRCVSRGAVFQIELNHPEARNPLGPEMIDALDAALTQAIEMPAARVV
CCCCCCCCCCCCCHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEE
LITAAGEAFSAGGNLGNMAERLNAPPGANGKDPIAQGNRRYGDFLRRLCSAPKVVVASVR
EEEECCCHHHCCCCHHHHHHHHCCCCCCCCCCCHHCCCCHHHHHHHHHHCCCCEEHHHHC
GAAMGGGAGLVCAADIAIGAQGAKFGFPEAAIGLVPGQILPFVAARIGAQAARRLMLTGE
CCCCCCCCCEEEEHHHHCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCC
RIDAAEAHRIGLLDYHVADPEQLAARTDELLARIVACAPGASAATKQMLHTVLGAKRWWS
CCCHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCC
DELPGYLDEAADTFARQMRSEAIEGVAAARGKRAPNWQQVIAARD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCC
>Mature Secondary Structure
MDTATPTVPQDAPVRCVSRGAVFQIELNHPEARNPLGPEMIDALDAALTQAIEMPAARVV
CCCCCCCCCCCCCHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEE
LITAAGEAFSAGGNLGNMAERLNAPPGANGKDPIAQGNRRYGDFLRRLCSAPKVVVASVR
EEEECCCHHHCCCCHHHHHHHHCCCCCCCCCCCHHCCCCHHHHHHHHHHCCCCEEHHHHC
GAAMGGGAGLVCAADIAIGAQGAKFGFPEAAIGLVPGQILPFVAARIGAQAARRLMLTGE
CCCCCCCCCEEEEHHHHCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCC
RIDAAEAHRIGLLDYHVADPEQLAARTDELLARIVACAPGASAATKQMLHTVLGAKRWWS
CCCHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCC
DELPGYLDEAADTFARQMRSEAIEGVAAARGKRAPNWQQVIAARD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9746358; 9738901 [H]