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The map label for this gene is ycgM [C]

Identifier: 121610742

GI number: 121610742

Start: 4219847

End: 4220542

Strand: Direct

Name: ycgM [C]

Synonym: Veis_3822

Alternate gene names: 121610742

Gene position: 4219847-4220542 (Clockwise)

Preceding gene: 121610737

Following gene: 121610743

Centisome position: 75.8

GC content: 66.95

Gene sequence:

>696_bases
ATGCGCTATGTGTTTCCTCCCGCGCCCGTGGTCAGCCTGCCCGTGGTGGGCAGCAACGACCGCTTTCCCGTGCACCGCGT
TTACTGCGTGGGCCGCAACTATGCAGAGCACGCCAAGGAAATGGGCTTCAGCGGCCGCGAGCCGCCGTTCTTCTTCATGA
AGCCTGCCGATGCCATCGTGGCGGTCAACGCCGGCGAAACCGGCCACTGGCCCTACCCCGGCCTCACCGCCAACCTGCAC
CACGAGATCGAACTCGTCGTGGCCATTGGCAAGGGGGGGTACCGCATCCCGGCGGCTGACGCTCCGCAGCATATCTACGG
CTACGCCGTGGGTCTGGACATGACACGCCGCGACCTGCAAAACGACATGAAAAAACAGGGCCGCCCCTGGTGCGTGGCCA
AGGGCTTTGACGCCAGCGCGCCGATCGGCCCGATCACGACGGCAGCACAGGCCGGCGCTGTAGAGCAGGCCGCGATCTGG
CTCCAGGTCAATGGCGTCGACCGCCAGCGCAGCACGATAGCGCAGCTCATCTGGAGCATTGCCGAGACCATCGAGCAACT
ATCCACCGCCTGGGCACTGCAACCCGGCGACCTGATCTACACCGGCACCCCCGAAGGCGTGGGCGCCGTCGTGCCTGGCG
ACACACTCACCGGCGGCGTCCAGGGCCTCACCCCGCTGCGCCTGCGCGTGGTGTGA

Upstream 100 bases:

>100_bases
GCGATCCATGCCGACCGCCCCCTGCCTTCGCCCTCCACCCCTTCACCCCTTCATCCTTCGCCCCCTGGTGCGCCGCCAGC
CCGAAAAACGAAAGCCCGAC

Downstream 100 bases:

>100_bases
GCGGTCGCCAACGCACCCACAGCCGCTATTTCGCTATTCTTTCTTTCGCTATTCTTTCAATAGCTGCAAACGCATGTTTT
GCAGGTACCACCCACCCACT

Product: fumarylacetoacetate (FAA) hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MRYVFPPAPVVSLPVVGSNDRFPVHRVYCVGRNYAEHAKEMGFSGREPPFFFMKPADAIVAVNAGETGHWPYPGLTANLH
HEIELVVAIGKGGYRIPAADAPQHIYGYAVGLDMTRRDLQNDMKKQGRPWCVAKGFDASAPIGPITTAAQAGAVEQAAIW
LQVNGVDRQRSTIAQLIWSIAETIEQLSTAWALQPGDLIYTGTPEGVGAVVPGDTLTGGVQGLTPLRLRVV

Sequences:

>Translated_231_residues
MRYVFPPAPVVSLPVVGSNDRFPVHRVYCVGRNYAEHAKEMGFSGREPPFFFMKPADAIVAVNAGETGHWPYPGLTANLH
HEIELVVAIGKGGYRIPAADAPQHIYGYAVGLDMTRRDLQNDMKKQGRPWCVAKGFDASAPIGPITTAAQAGAVEQAAIW
LQVNGVDRQRSTIAQLIWSIAETIEQLSTAWALQPGDLIYTGTPEGVGAVVPGDTLTGGVQGLTPLRLRVV
>Mature_231_residues
MRYVFPPAPVVSLPVVGSNDRFPVHRVYCVGRNYAEHAKEMGFSGREPPFFFMKPADAIVAVNAGETGHWPYPGLTANLH
HEIELVVAIGKGGYRIPAADAPQHIYGYAVGLDMTRRDLQNDMKKQGRPWCVAKGFDASAPIGPITTAAQAGAVEQAAIW
LQVNGVDRQRSTIAQLIWSIAETIEQLSTAWALQPGDLIYTGTPEGVGAVVPGDTLTGGVQGLTPLRLRVV

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI13654274, Length=204, Percent_Identity=40.1960784313725, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI215422413, Length=197, Percent_Identity=41.1167512690355, Blast_Score=154, Evalue=6e-38,
Organism=Homo sapiens, GI66348062, Length=197, Percent_Identity=41.1167512690355, Blast_Score=154, Evalue=6e-38,
Organism=Homo sapiens, GI156231349, Length=184, Percent_Identity=35.3260869565217, Blast_Score=107, Evalue=6e-24,
Organism=Homo sapiens, GI40786394, Length=184, Percent_Identity=34.7826086956522, Blast_Score=104, Evalue=6e-23,
Organism=Escherichia coli, GI1787428, Length=197, Percent_Identity=40.6091370558376, Blast_Score=143, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17557057, Length=195, Percent_Identity=38.4615384615385, Blast_Score=140, Evalue=6e-34,
Organism=Saccharomyces cerevisiae, GI6324161, Length=218, Percent_Identity=32.5688073394495, Blast_Score=128, Evalue=9e-31,
Organism=Drosophila melanogaster, GI28572127, Length=214, Percent_Identity=30.3738317757009, Blast_Score=110, Evalue=9e-25,
Organism=Drosophila melanogaster, GI28571789, Length=206, Percent_Identity=29.126213592233, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24663695, Length=214, Percent_Identity=27.5700934579439, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 24869; Mature: 24869

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYVFPPAPVVSLPVVGSNDRFPVHRVYCVGRNYAEHAKEMGFSGREPPFFFMKPADAIV
CCCCCCCCCEEEEEEECCCCCCCEEEEEEECCCHHHHHHHCCCCCCCCCEEEECCCCEEE
AVNAGETGHWPYPGLTANLHHEIELVVAIGKGGYRIPAADAPQHIYGYAVGLDMTRRDLQ
EEECCCCCCCCCCCCEECCCEEEEEEEEECCCCEECCCCCCCCCEEEEEECCCHHHHHHH
NDMKKQGRPWCVAKGFDASAPIGPITTAAQAGAVEQAAIWLQVNGVDRQRSTIAQLIWSI
HHHHHCCCCEEEECCCCCCCCCCCCHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHHH
AETIEQLSTAWALQPGDLIYTGTPEGVGAVVPGDTLTGGVQGLTPLRLRVV
HHHHHHHHHHHCCCCCCEEEECCCCCCEEEECCCCCCCCCCCCCCEEEEEC
>Mature Secondary Structure
MRYVFPPAPVVSLPVVGSNDRFPVHRVYCVGRNYAEHAKEMGFSGREPPFFFMKPADAIV
CCCCCCCCCEEEEEEECCCCCCCEEEEEEECCCHHHHHHHCCCCCCCCCEEEECCCCEEE
AVNAGETGHWPYPGLTANLHHEIELVVAIGKGGYRIPAADAPQHIYGYAVGLDMTRRDLQ
EEECCCCCCCCCCCCEECCCEEEEEEEEECCCCEECCCCCCCCCEEEEEECCCHHHHHHH
NDMKKQGRPWCVAKGFDASAPIGPITTAAQAGAVEQAAIWLQVNGVDRQRSTIAQLIWSI
HHHHHCCCCEEEECCCCCCCCCCCCHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHHH
AETIEQLSTAWALQPGDLIYTGTPEGVGAVVPGDTLTGGVQGLTPLRLRVV
HHHHHHHHHHHCCCCCCEEEECCCCCCEEEECCCCCCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]