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The map label for this gene is recG [H]

Identifier: 121610609

GI number: 121610609

Start: 4072592

End: 4074481

Strand: Direct

Name: recG [H]

Synonym: Veis_3682

Alternate gene names: 121610609

Gene position: 4072592-4074481 (Clockwise)

Preceding gene: 121610607

Following gene: 121610617

Centisome position: 73.16

GC content: 67.72

Gene sequence:

>1890_bases
ATGGGGGATCGGGCCGATTTTTTCGCACTACCCTGTCTCGGCTGCCGCAATGCGGCCGAGGCGCTGCTGTGCCTGCCCAA
GACCTACATCGATAAAACCCGTGCGCACGAGCGCATTCACCGGGCGCCAGCGGAGCGCGCAGCGCTTTTTCAGGGCAAGT
TGGTCCGTTGCCGTGGTCTGAACGCCGATGGGCAAGCCACGCGCAGCCCCTTTGCTCGATTTGCGCGATTTGCGCACTCG
GTGGAATTGACGGTGGACTTTGCCGACGCCAGCGCGATGCGCGTTCGGCTTTTCGGCGCGCGCATCGAGGAACTCGCCGC
GCTCGTCGATCAGACCATCGTGCTGCAAGCCTGCGCGCGCCCGTTGGCAAACGGGCCGACGAGCCTGCACGGCGCCACGC
TCGCGGCCGTCACCGGCTGCATCGAGCCCCAGTATGTCGGCGTGCCCGGCGGGATTTCCGGCCAGAAGATCCGGTGCGCA
GTCCATGCCGCGCTGGGCATCGAGGGCAGTCTGGATCAGGCGGCGCTGCTGCTGCAAGGCAATGCGCCCATCGAGTCCGT
GCTGCACGAGCACGGCATCACGGCCCGCGCGCTGCTGCAAGACCTGCACCGGCCAGCCACACTGCGTGCCGGCGACACGG
CGCTTGCCATCGCCCGCGCCTGCGTGGTGCGCGAGATCCGCAGCGCGGCCGTTGCCAGTCGGGTGGTCGCCGCGCCCTGC
CCCTACGACATCGACCAGCACCTGATCGCCCTCGTGGCCGCGCAGAAGGAAACGCTCAGCCAGGATCAGCGCCGGGCGCT
CAACGCCATTCGCCTGCAGGTCAACGACCGGCGGGGCGCCCGCATCCTGCTCAATGGCGATGTGGGCACGGGCAAGACCC
TGGTGTTTCTGCTCGCGCTCGCGGCCATCGCCAGCACCAGCGGCAAGCGCGTTGCCGTGGTCGTTCCCAGCGACCTGGTG
GCCCGACAGATCCACGCCCAGGCCCAGGCGCGCTTTCCGCAACTGCAACCCTGCCTGGTGATGGCCGGCAGCGGCGATGT
GCCCGATGACAGCCTGATGCTGATCGGCACACAGGCCCTGTTCCATCGGGCTGAGCATCTCGAGCTCGAGGCCCTGGTGG
TCGATGAGCAGCACAAGTTCTCGGTGGCGCAGCGCACCGTGCTCGCGCGCGGCCACACCCATGTGATCGAGGCCAGCGCC
ACGCCCATCCCGCGCTCGCTGGCCCTGGCCATCTTCGACGGCTGGATGCAGGTGCGCATCGTCAACTGCCCGGTGCAAAA
AACCATCGTCTCACGCATCGCCATGCCCGAGAGCCGGCGCAAAGTGGTTGCGCTGGCCCATGCCCACTTGCAGCGTGGCC
ACAAGGTTGTCTTCCTCTACCCGAAGGTGGACGGCCAAGGCGCAACGGTGCGCGCTGCCGGCGAACGGCTGGACAAGCAC
TTCCAGGGCAAGGTGGCCGTCGTGCACGGACAGATGGGCCGTGATGCCAAGGAATCGGCCCTGAAGGCGTTTGCCAGCGG
CGAGCGCCCGATCATCGCTGCCAGCACGGCCGTGGAGGTCGGCGTCGATGTGCCCGACATTGGCCTGATGGTCGTCAGCG
GCGCCGATCGCTTCGCCGTGGCCCAGTTGCACCAACTGCGCGGGCGGCTGGCGCGCAACGGCGGCAAGGCCCACTTCGTG
ATGATGCTCGACAAGAAGCCGTCGAAGCTGACCGAGTTGCGGCTGCGGGCCGTTTGCCAGCATGCCGATGGCTTCTCGCT
GGCAGAGCGCGACATGGAGCTTCGCGGCTTCGGGGATGTGCTCGGCGATCTCCAGTCGGGCCAGTCCAGCGCCACCTTCA
AACTGCCGCGCCTGCAAGTGGCGGATTTCACCAAGCCCGCAGGGGTGTAG

Upstream 100 bases:

>100_bases
GATACATGCGGCCATGGATCGCCGGCCGTGCGAATGCCTGTCTGTTCGAGGCATGATTTATCGCTCTTGAATCACGCTCT
GTCTGGTGTATGGTTTGGGC

Downstream 100 bases:

>100_bases
CGCGGGGACAGGTTTGCCGACGGGCTGTCCCACCGGGAAACCCGCCACCGCCACTACGACCCATGGCGCCGGAAGTTCCA
CGGTGCAATCGGCCTGGGAT

Product: helicase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 629; Mature: 628

Protein sequence:

>629_residues
MGDRADFFALPCLGCRNAAEALLCLPKTYIDKTRAHERIHRAPAERAALFQGKLVRCRGLNADGQATRSPFARFARFAHS
VELTVDFADASAMRVRLFGARIEELAALVDQTIVLQACARPLANGPTSLHGATLAAVTGCIEPQYVGVPGGISGQKIRCA
VHAALGIEGSLDQAALLLQGNAPIESVLHEHGITARALLQDLHRPATLRAGDTALAIARACVVREIRSAAVASRVVAAPC
PYDIDQHLIALVAAQKETLSQDQRRALNAIRLQVNDRRGARILLNGDVGTGKTLVFLLALAAIASTSGKRVAVVVPSDLV
ARQIHAQAQARFPQLQPCLVMAGSGDVPDDSLMLIGTQALFHRAEHLELEALVVDEQHKFSVAQRTVLARGHTHVIEASA
TPIPRSLALAIFDGWMQVRIVNCPVQKTIVSRIAMPESRRKVVALAHAHLQRGHKVVFLYPKVDGQGATVRAAGERLDKH
FQGKVAVVHGQMGRDAKESALKAFASGERPIIAASTAVEVGVDVPDIGLMVVSGADRFAVAQLHQLRGRLARNGGKAHFV
MMLDKKPSKLTELRLRAVCQHADGFSLAERDMELRGFGDVLGDLQSGQSSATFKLPRLQVADFTKPAGV

Sequences:

>Translated_629_residues
MGDRADFFALPCLGCRNAAEALLCLPKTYIDKTRAHERIHRAPAERAALFQGKLVRCRGLNADGQATRSPFARFARFAHS
VELTVDFADASAMRVRLFGARIEELAALVDQTIVLQACARPLANGPTSLHGATLAAVTGCIEPQYVGVPGGISGQKIRCA
VHAALGIEGSLDQAALLLQGNAPIESVLHEHGITARALLQDLHRPATLRAGDTALAIARACVVREIRSAAVASRVVAAPC
PYDIDQHLIALVAAQKETLSQDQRRALNAIRLQVNDRRGARILLNGDVGTGKTLVFLLALAAIASTSGKRVAVVVPSDLV
ARQIHAQAQARFPQLQPCLVMAGSGDVPDDSLMLIGTQALFHRAEHLELEALVVDEQHKFSVAQRTVLARGHTHVIEASA
TPIPRSLALAIFDGWMQVRIVNCPVQKTIVSRIAMPESRRKVVALAHAHLQRGHKVVFLYPKVDGQGATVRAAGERLDKH
FQGKVAVVHGQMGRDAKESALKAFASGERPIIAASTAVEVGVDVPDIGLMVVSGADRFAVAQLHQLRGRLARNGGKAHFV
MMLDKKPSKLTELRLRAVCQHADGFSLAERDMELRGFGDVLGDLQSGQSSATFKLPRLQVADFTKPAGV
>Mature_628_residues
GDRADFFALPCLGCRNAAEALLCLPKTYIDKTRAHERIHRAPAERAALFQGKLVRCRGLNADGQATRSPFARFARFAHSV
ELTVDFADASAMRVRLFGARIEELAALVDQTIVLQACARPLANGPTSLHGATLAAVTGCIEPQYVGVPGGISGQKIRCAV
HAALGIEGSLDQAALLLQGNAPIESVLHEHGITARALLQDLHRPATLRAGDTALAIARACVVREIRSAAVASRVVAAPCP
YDIDQHLIALVAAQKETLSQDQRRALNAIRLQVNDRRGARILLNGDVGTGKTLVFLLALAAIASTSGKRVAVVVPSDLVA
RQIHAQAQARFPQLQPCLVMAGSGDVPDDSLMLIGTQALFHRAEHLELEALVVDEQHKFSVAQRTVLARGHTHVIEASAT
PIPRSLALAIFDGWMQVRIVNCPVQKTIVSRIAMPESRRKVVALAHAHLQRGHKVVFLYPKVDGQGATVRAAGERLDKHF
QGKVAVVHGQMGRDAKESALKAFASGERPIIAASTAVEVGVDVPDIGLMVVSGADRFAVAQLHQLRGRLARNGGKAHFVM
MLDKKPSKLTELRLRAVCQHADGFSLAERDMELRGFGDVLGDLQSGQSSATFKLPRLQVADFTKPAGV

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=368, Percent_Identity=33.1521739130435, Blast_Score=166, Evalue=4e-42,
Organism=Escherichia coli, GI1787357, Length=369, Percent_Identity=31.7073170731707, Blast_Score=149, Evalue=4e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 67432; Mature: 67301

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDRADFFALPCLGCRNAAEALLCLPKTYIDKTRAHERIHRAPAERAALFQGKLVRCRGL
CCCCCCEEEECCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHHHCCCEEEEECC
NADGQATRSPFARFARFAHSVELTVDFADASAMRVRLFGARIEELAALVDQTIVLQACAR
CCCCCCHHHHHHHHHHHHCEEEEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
PLANGPTSLHGATLAAVTGCIEPQYVGVPGGISGQKIRCAVHAALGIEGSLDQAALLLQG
HHCCCCCCCCCHHHHHHHHCCCCCEECCCCCCCCCEEEEEEEEECCCCCCCCCEEEEEEC
NAPIESVLHEHGITARALLQDLHRPATLRAGDTALAIARACVVREIRSAAVASRVVAAPC
CCCHHHHHHHCCCHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PYDIDQHLIALVAAQKETLSQDQRRALNAIRLQVNDRRGARILLNGDVGTGKTLVFLLAL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCEEEEECCCCCCHHHHHHHHH
AAIASTSGKRVAVVVPSDLVARQIHAQAQARFPQLQPCLVMAGSGDVPDDSLMLIGTQAL
HHHHCCCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCEEEEECHHH
FHRAEHLELEALVVDEQHKFSVAQRTVLARGHTHVIEASATPIPRSLALAIFDGWMQVRI
HHHHHCCEEEEEEECCCHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHCCCEEEEEE
VNCPVQKTIVSRIAMPESRRKVVALAHAHLQRGHKVVFLYPKVDGQGATVRAAGERLDKH
ECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCEEEHHHHHHHHH
FQGKVAVVHGQMGRDAKESALKAFASGERPIIAASTAVEVGVDVPDIGLMVVSGADRFAV
HCCCEEEEECCCCCCHHHHHHHHHHCCCCCEEEECCEEEECCCCCCCCEEEEECCCHHHH
AQLHQLRGRLARNGGKAHFVMMLDKKPSKLTELRLRAVCQHADGFSLAERDMELRGFGDV
HHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHH
LGDLQSGQSSATFKLPRLQVADFTKPAGV
HHHHHCCCCCCEEECCCEEECCCCCCCCC
>Mature Secondary Structure 
GDRADFFALPCLGCRNAAEALLCLPKTYIDKTRAHERIHRAPAERAALFQGKLVRCRGL
CCCCCEEEECCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHHHCCCEEEEECC
NADGQATRSPFARFARFAHSVELTVDFADASAMRVRLFGARIEELAALVDQTIVLQACAR
CCCCCCHHHHHHHHHHHHCEEEEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
PLANGPTSLHGATLAAVTGCIEPQYVGVPGGISGQKIRCAVHAALGIEGSLDQAALLLQG
HHCCCCCCCCCHHHHHHHHCCCCCEECCCCCCCCCEEEEEEEEECCCCCCCCCEEEEEEC
NAPIESVLHEHGITARALLQDLHRPATLRAGDTALAIARACVVREIRSAAVASRVVAAPC
CCCHHHHHHHCCCHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PYDIDQHLIALVAAQKETLSQDQRRALNAIRLQVNDRRGARILLNGDVGTGKTLVFLLAL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCEEEEECCCCCCHHHHHHHHH
AAIASTSGKRVAVVVPSDLVARQIHAQAQARFPQLQPCLVMAGSGDVPDDSLMLIGTQAL
HHHHCCCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCEEEEECHHH
FHRAEHLELEALVVDEQHKFSVAQRTVLARGHTHVIEASATPIPRSLALAIFDGWMQVRI
HHHHHCCEEEEEEECCCHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHCCCEEEEEE
VNCPVQKTIVSRIAMPESRRKVVALAHAHLQRGHKVVFLYPKVDGQGATVRAAGERLDKH
ECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCEEEHHHHHHHHH
FQGKVAVVHGQMGRDAKESALKAFASGERPIIAASTAVEVGVDVPDIGLMVVSGADRFAV
HCCCEEEEECCCCCCHHHHHHHHHHCCCCCEEEECCEEEECCCCCCCCEEEEECCCHHHH
AQLHQLRGRLARNGGKAHFVMMLDKKPSKLTELRLRAVCQHADGFSLAERDMELRGFGDV
HHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHH
LGDLQSGQSSATFKLPRLQVADFTKPAGV
HHHHHCCCCCCEEECCCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8830261; 11463916 [H]