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The map label for this gene is ligD [H]

Identifier: 121609782

GI number: 121609782

Start: 3184875

End: 3185804

Strand: Direct

Name: ligD [H]

Synonym: Veis_2833

Alternate gene names: 121609782

Gene position: 3184875-3185804 (Clockwise)

Preceding gene: 121609781

Following gene: 121609783

Centisome position: 57.21

GC content: 68.39

Gene sequence:

>930_bases
ATGATCGAAGACTTCAACGGCAAGACCGCCGTGCTGACCGGCGCAGGCTCCGGCTTTGGCCTCGAATGCGCCCGCATCGG
CGCGCGCCTGGGCATGAACCTGGTGCTGGTCGATGTGCAACGGGACGCGCTCGACACCGCAGCGGCCGAAATGCGGGCCA
GTTGCAGCCCGGGCCGCCAGGTGCTGGCCCGCCAGGTGGACGTGGCAAACGCCGCCGGAATGCAGCAGTTGGCCGAAGAC
GTGCAGCAGCGCCTCGGCGCGCCGCACCTGGTGTTCAACAACGCCGGCGTGGGCGCAGGCGGCCTGGTGTGGGAGAACTC
GGTCAAGGACTGGGAATGGGTGCTGGGCGTGAACCTGTGGGGGGTGGTGCACGGCGTGCGTCTGTTCACCCCGATGATGC
TCGCCGCCGCAGGCAAAGACCCGGCCTGGCGCGGCCACATCGTCAACACCGCCAGCATGGCGGGACTGCTGGCAGCCCCC
AACATGGGCATCTACAACGTCAGCAAGCACGCGGTGGTCAGCCTGTCGGAGACGCTGTACCAAGACCTGGCGCTGGTCAC
GGACCAGATCGGCGCCAGCGTGCTATGCCCCTTTTTCGTCTCCACCGCCATCCACCAGAGCCAGCGCAACCGCCCCGCCA
GCCTGCCGGCCGACAGGCCCACCCGAAGCCAACGCATCAGCCGGGCCATGAGCAACAAGGCCGTGGGCAGCGGCAAGGTC
AGCGCCGCTGCCGTTGCCCAAAAGGTGTTCGACGCCGTCGCCCAAGGCCGGTTCTACATCTACAGCCACCCCAAGTCCCT
GGCCTCCGTGCAGACGCGCATGGAAGACATCGTGCTGGGCCGCAACCCCACCGACCCCCTGGCCGACAAACCCGAAATCG
GCGCGCAATTGCGCGCCGCGCTGCGCGCCGATGAAGCCGCAGGCGCCTGA

Upstream 100 bases:

>100_bases
GGGATCGACTTCGAGGGCCTGCTGGCGCGCGCCTTGCCCGTCTGAGCCGGCAGGTGCATCGACCTGCCGTATGGCTGACC
TGTAGCGAAAGGAATCGGAA

Downstream 100 bases:

>100_bases
GCCGTGATTCCATTTCCCAATCGTTCGTGAGCGCGAAGGCGAAGCGCAGACAGCACGAATGCACGGCAAGCGACGCCGGC
AAAGCGCACGGATGATTCGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MIEDFNGKTAVLTGAGSGFGLECARIGARLGMNLVLVDVQRDALDTAAAEMRASCSPGRQVLARQVDVANAAGMQQLAED
VQQRLGAPHLVFNNAGVGAGGLVWENSVKDWEWVLGVNLWGVVHGVRLFTPMMLAAAGKDPAWRGHIVNTASMAGLLAAP
NMGIYNVSKHAVVSLSETLYQDLALVTDQIGASVLCPFFVSTAIHQSQRNRPASLPADRPTRSQRISRAMSNKAVGSGKV
SAAAVAQKVFDAVAQGRFYIYSHPKSLASVQTRMEDIVLGRNPTDPLADKPEIGAQLRAALRADEAAGA

Sequences:

>Translated_309_residues
MIEDFNGKTAVLTGAGSGFGLECARIGARLGMNLVLVDVQRDALDTAAAEMRASCSPGRQVLARQVDVANAAGMQQLAED
VQQRLGAPHLVFNNAGVGAGGLVWENSVKDWEWVLGVNLWGVVHGVRLFTPMMLAAAGKDPAWRGHIVNTASMAGLLAAP
NMGIYNVSKHAVVSLSETLYQDLALVTDQIGASVLCPFFVSTAIHQSQRNRPASLPADRPTRSQRISRAMSNKAVGSGKV
SAAAVAQKVFDAVAQGRFYIYSHPKSLASVQTRMEDIVLGRNPTDPLADKPEIGAQLRAALRADEAAGA
>Mature_309_residues
MIEDFNGKTAVLTGAGSGFGLECARIGARLGMNLVLVDVQRDALDTAAAEMRASCSPGRQVLARQVDVANAAGMQQLAED
VQQRLGAPHLVFNNAGVGAGGLVWENSVKDWEWVLGVNLWGVVHGVRLFTPMMLAAAGKDPAWRGHIVNTASMAGLLAAP
NMGIYNVSKHAVVSLSETLYQDLALVTDQIGASVLCPFFVSTAIHQSQRNRPASLPADRPTRSQRISRAMSNKAVGSGKV
SAAAVAQKVFDAVAQGRFYIYSHPKSLASVQTRMEDIVLGRNPTDPLADKPEIGAQLRAALRADEAAGA

Specific function: Catalyzes the C alpha dehydrogenation of arylglycerol- beta-aryl ether (C alpha alcohol type) (compound IV) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40807363, Length=264, Percent_Identity=26.1363636363636, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI31542939, Length=202, Percent_Identity=30.6930693069307, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI142976729, Length=198, Percent_Identity=30.8080808080808, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI25282469, Length=241, Percent_Identity=27.8008298755187, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI20149619, Length=195, Percent_Identity=27.1794871794872, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI224922801, Length=173, Percent_Identity=30.635838150289, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI87082100, Length=204, Percent_Identity=30.8823529411765, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI87082160, Length=227, Percent_Identity=25.5506607929515, Blast_Score=61, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI193203115, Length=219, Percent_Identity=27.3972602739726, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI193203117, Length=221, Percent_Identity=27.1493212669683, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17564282, Length=212, Percent_Identity=27.3584905660377, Blast_Score=81, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17508895, Length=203, Percent_Identity=26.1083743842365, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71994604, Length=227, Percent_Identity=24.2290748898678, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17507613, Length=275, Percent_Identity=24.7272727272727, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI32563809, Length=275, Percent_Identity=24.7272727272727, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17567345, Length=217, Percent_Identity=27.6497695852535, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI281364892, Length=216, Percent_Identity=25.9259259259259, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24581726, Length=240, Percent_Identity=27.0833333333333, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24644339, Length=183, Percent_Identity=30.0546448087432, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24640492, Length=223, Percent_Identity=25.5605381165919, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28571526, Length=205, Percent_Identity=28.780487804878, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21355631, Length=202, Percent_Identity=27.2277227722772, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24639444, Length=199, Percent_Identity=28.643216080402, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI281364494, Length=216, Percent_Identity=27.3148148148148, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24665243, Length=194, Percent_Identity=28.3505154639175, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI221331218, Length=194, Percent_Identity=28.3505154639175, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21357041, Length=181, Percent_Identity=28.1767955801105, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28571387, Length=212, Percent_Identity=26.4150943396226, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 32666; Mature: 32666

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEDFNGKTAVLTGAGSGFGLECARIGARLGMNLVLVDVQRDALDTAAAEMRASCSPGRQ
CCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHCCCHHHH
VLARQVDVANAAGMQQLAEDVQQRLGAPHLVFNNAGVGAGGLVWENSVKDWEWVLGVNLW
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCEECCCCCCEEEEECCHHH
GVVHGVRLFTPMMLAAAGKDPAWRGHIVNTASMAGLLAAPNMGIYNVSKHAVVSLSETLY
HHHHHHHHHHHHHHHHCCCCCCCCCEEECHHHHHHHHCCCCCCEEECCHHHHHHHHHHHH
QDLALVTDQIGASVLCPFFVSTAIHQSQRNRPASLPADRPTRSQRISRAMSNKAVGSGKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCH
SAAAVAQKVFDAVAQGRFYIYSHPKSLASVQTRMEDIVLGRNPTDPLADKPEIGAQLRAA
HHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
LRADEAAGA
HHHHHCCCC
>Mature Secondary Structure
MIEDFNGKTAVLTGAGSGFGLECARIGARLGMNLVLVDVQRDALDTAAAEMRASCSPGRQ
CCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHCCCHHHH
VLARQVDVANAAGMQQLAEDVQQRLGAPHLVFNNAGVGAGGLVWENSVKDWEWVLGVNLW
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCEECCCCCCEEEEECCHHH
GVVHGVRLFTPMMLAAAGKDPAWRGHIVNTASMAGLLAAPNMGIYNVSKHAVVSLSETLY
HHHHHHHHHHHHHHHHCCCCCCCCCEEECHHHHHHHHCCCCCCEEECCHHHHHHHHHHHH
QDLALVTDQIGASVLCPFFVSTAIHQSQRNRPASLPADRPTRSQRISRAMSNKAVGSGKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCH
SAAAVAQKVFDAVAQGRFYIYSHPKSLASVQTRMEDIVLGRNPTDPLADKPEIGAQLRAA
HHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
LRADEAAGA
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1744051; 8495726; 7764263 [H]