Click here to switch to the map view.

The map label for this gene is paaG [C]

Identifier: 121609713

GI number: 121609713

Start: 3110956

End: 3111741

Strand: Direct

Name: paaG [C]

Synonym: Veis_2761

Alternate gene names: 121609713

Gene position: 3110956-3111741 (Clockwise)

Preceding gene: 121609711

Following gene: 121609715

Centisome position: 55.88

GC content: 66.67

Gene sequence:

>786_bases
GTGGATTTCGCAGAACTGCAATACGCGGTCGTGGGCCGGGCCGCCGTGCTCACCATCCACCGGCCCGAGCGTCTGAACGC
CTGGACGCCAACGCTGGAAGCCGAACTCCGATCGGCCATCCGGCAAGCCAACCAGGATGACGGCGTGCGCTGCGCCGTGT
TGACCGGGGCAGGACGGGCCTTTTGCGCCGGAATGGATATGCAGGTGCTGCGCGCAGGCCAGACCAACACCCGAGCGCCC
GGCGCGTCCGATGAGGACGCGGCCCAGCGCTACGGCTATCTGTGGGATTTCGACAAACCCTTGGTTGCCGCGATCAATGG
CGCGACGGCCGGCGTCGGGTTGTGTCTGGCGCTGTACTGCGACCTGCGGTACGTCGCGGCTGGCGCCAAGATCACGGCAC
CCTATGCCCGCCGCGGCCTCGTGGCTGAGCACGGCATGGCCTGGCTCTTGCCACGCCTGATAGGCCCCATGCATGCGGCC
GACCTGCTGCTGTCGGGCCGCACGATCCTGGGCGAGGAGGCCGAACGCATGGGCTTGGCCAACCTGCTGCCGGCCGAGGG
CTTCTTGAACGCCGTGATGCAGCGCGTGCAGGAGATTGCCACGGCCACATCGCCGCGCTCGATTCGCATCATCAAACATC
AGTTGCGCCAAGCCCGCTACCAGACGTTGGGCCAGGCCACCCGCAGCGCCGACCTGGAAATCGCCGCCTGCCGCCACACC
GAAGACTTCAAGGAAGGTGTGCAGCACTTTCTGGAAAAGCGCTCCCCCCAATTCACCGGTAGGTAG

Upstream 100 bases:

>100_bases
TTTCGATAAGCGAAATTCTGGACTCGTCCCGCCTTGTCCACCCGCAGGTGCGCGGGAATACTGGGCGCTCGCCGACACCA
GAACGACATCGGAGACAAAC

Downstream 100 bases:

>100_bases
ACATGGCAGACAACGACATGGCACAGCCGCTCGCAGGCATCCGGGTCGTCGAAATCGGGCAGAACATCGCGGGGCCTTAC
GCAAGCGAGATCCTGTCCTC

Product: enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MDFAELQYAVVGRAAVLTIHRPERLNAWTPTLEAELRSAIRQANQDDGVRCAVLTGAGRAFCAGMDMQVLRAGQTNTRAP
GASDEDAAQRYGYLWDFDKPLVAAINGATAGVGLCLALYCDLRYVAAGAKITAPYARRGLVAEHGMAWLLPRLIGPMHAA
DLLLSGRTILGEEAERMGLANLLPAEGFLNAVMQRVQEIATATSPRSIRIIKHQLRQARYQTLGQATRSADLEIAACRHT
EDFKEGVQHFLEKRSPQFTGR

Sequences:

>Translated_261_residues
MDFAELQYAVVGRAAVLTIHRPERLNAWTPTLEAELRSAIRQANQDDGVRCAVLTGAGRAFCAGMDMQVLRAGQTNTRAP
GASDEDAAQRYGYLWDFDKPLVAAINGATAGVGLCLALYCDLRYVAAGAKITAPYARRGLVAEHGMAWLLPRLIGPMHAA
DLLLSGRTILGEEAERMGLANLLPAEGFLNAVMQRVQEIATATSPRSIRIIKHQLRQARYQTLGQATRSADLEIAACRHT
EDFKEGVQHFLEKRSPQFTGR
>Mature_261_residues
MDFAELQYAVVGRAAVLTIHRPERLNAWTPTLEAELRSAIRQANQDDGVRCAVLTGAGRAFCAGMDMQVLRAGQTNTRAP
GASDEDAAQRYGYLWDFDKPLVAAINGATAGVGLCLALYCDLRYVAAGAKITAPYARRGLVAEHGMAWLLPRLIGPMHAA
DLLLSGRTILGEEAERMGLANLLPAEGFLNAVMQRVQEIATATSPRSIRIIKHQLRQARYQTLGQATRSADLEIAACRHT
EDFKEGVQHFLEKRSPQFTGR

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=244, Percent_Identity=28.2786885245902, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI45643119, Length=248, Percent_Identity=25.4032258064516, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI260275230, Length=248, Percent_Identity=25.4032258064516, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI260274832, Length=248, Percent_Identity=25.4032258064516, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI20127408, Length=183, Percent_Identity=32.7868852459016, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI221136756, Length=193, Percent_Identity=27.4611398963731, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI221136753, Length=193, Percent_Identity=27.4611398963731, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI116235487, Length=182, Percent_Identity=29.6703296703297, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI221307494, Length=193, Percent_Identity=27.4611398963731, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI70995211, Length=253, Percent_Identity=25.296442687747, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI68989263, Length=175, Percent_Identity=34.2857142857143, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI25453481, Length=189, Percent_Identity=26.4550264550265, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI51538573, Length=189, Percent_Identity=26.4550264550265, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI4757966, Length=189, Percent_Identity=26.4550264550265, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI51538581, Length=189, Percent_Identity=26.4550264550265, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI4757968, Length=189, Percent_Identity=26.4550264550265, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI49355787, Length=189, Percent_Identity=26.4550264550265, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI37594469, Length=172, Percent_Identity=29.6511627906977, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI37594471, Length=172, Percent_Identity=29.6511627906977, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1787660, Length=253, Percent_Identity=34.7826086956522, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1787659, Length=264, Percent_Identity=30.3030303030303, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI221142681, Length=255, Percent_Identity=30.5882352941176, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI87082183, Length=278, Percent_Identity=24.8201438848921, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788597, Length=260, Percent_Identity=28.8461538461538, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788682, Length=200, Percent_Identity=27.5, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17554946, Length=248, Percent_Identity=28.6290322580645, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI25145438, Length=248, Percent_Identity=28.2258064516129, Blast_Score=98, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17560910, Length=251, Percent_Identity=29.0836653386454, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17535521, Length=247, Percent_Identity=22.6720647773279, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17534483, Length=262, Percent_Identity=24.4274809160305, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17549921, Length=214, Percent_Identity=26.6355140186916, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17536985, Length=221, Percent_Identity=25.7918552036199, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI25144276, Length=159, Percent_Identity=31.4465408805031, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17508953, Length=159, Percent_Identity=31.4465408805031, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17508951, Length=159, Percent_Identity=31.4465408805031, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320241, Length=206, Percent_Identity=25.7281553398058, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI20129971, Length=245, Percent_Identity=31.4285714285714, Blast_Score=111, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24653477, Length=245, Percent_Identity=31.4285714285714, Blast_Score=111, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24653139, Length=254, Percent_Identity=26.7716535433071, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21357171, Length=257, Percent_Identity=27.6264591439689, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24654903, Length=216, Percent_Identity=22.6851851851852, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI19922422, Length=248, Percent_Identity=24.1935483870968, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24650670, Length=176, Percent_Identity=31.25, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 28501; Mature: 28501

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFAELQYAVVGRAAVLTIHRPERLNAWTPTLEAELRSAIRQANQDDGVRCAVLTGAGRA
CCHHHHHHHHHCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCH
FCAGMDMQVLRAGQTNTRAPGASDEDAAQRYGYLWDFDKPLVAAINGATAGVGLCLALYC
HHCCCCHHHHHCCCCCCCCCCCCCHHHHHHCCCCCCCCCHHHHHHCCCHHHHHHHHHHHH
DLRYVAAGAKITAPYARRGLVAEHGMAWLLPRLIGPMHAADLLLSGRTILGEEAERMGLA
HHHHHHCCCEEECHHHHCCCHHHCCHHHHHHHHHCHHHHHHHHHCCCHHHCCHHHHCCHH
NLLPAEGFLNAVMQRVQEIATATSPRSIRIIKHQLRQARYQTLGQATRSADLEIAACRHT
HHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCC
EDFKEGVQHFLEKRSPQFTGR
HHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MDFAELQYAVVGRAAVLTIHRPERLNAWTPTLEAELRSAIRQANQDDGVRCAVLTGAGRA
CCHHHHHHHHHCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCH
FCAGMDMQVLRAGQTNTRAPGASDEDAAQRYGYLWDFDKPLVAAINGATAGVGLCLALYC
HHCCCCHHHHHCCCCCCCCCCCCCHHHHHHCCCCCCCCCHHHHHHCCCHHHHHHHHHHHH
DLRYVAAGAKITAPYARRGLVAEHGMAWLLPRLIGPMHAADLLLSGRTILGEEAERMGLA
HHHHHHCCCEEECHHHHCCCHHHCCHHHHHHHHHCHHHHHHHHHCCCHHHCCHHHHCCHH
NLLPAEGFLNAVMQRVQEIATATSPRSIRIIKHQLRQARYQTLGQATRSADLEIAACRHT
HHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCC
EDFKEGVQHFLEKRSPQFTGR
HHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA