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The map label for this gene is lacD1 [H]

Identifier: 121609553

GI number: 121609553

Start: 2940099

End: 2941145

Strand: Direct

Name: lacD1 [H]

Synonym: Veis_2597

Alternate gene names: 121609553

Gene position: 2940099-2941145 (Clockwise)

Preceding gene: 121609552

Following gene: 121609554

Centisome position: 52.82

GC content: 68.19

Gene sequence:

>1047_bases
ATGCAAATTTCCGCCGGCAAGCTGTGGTCGATGCGCCGTCTCGCCGACGAACGCGGTTTTTTCAAGATGACGGCTGTCGA
CCAGCGGCCTGGCGTGGAAGCGCTGGTACGCCAGCGGCGCGGGGCTGGTGGGGCTGGTGCGTGCCTCTTCGAGGATGTCG
GCCAGGTCAAGCGCGTGCTGATCGAAACCCTGTCGCCCTGGTCGAGCGCGATGCTGCTCGACCCGGGCTACGCCTATCCG
CGCGCCGCGTTGCAAGCCGATCCGCGCAAAGGATTGCTGCTGACCTACGAGCAATGGGACTGCGAGGAAACGCCCGGCGG
CCGCAAGACCTTCGCCTACCGCGACTGGTCGGTCGAGAAGATCAAGCGCCTGGGTGCCGATGGCGTCAAGCTGATGCTGT
GGTGGCGTCCTGATGCGAGCAAAGACGTGAAGCTGCATCAGCGTGCGCTGGTCGAACAGGTGGGCCGCGACTGCCGCCGG
CACGATATCGCCTTCCTGCTGGAGCCGCTGCTCTACCCGCCGGGCAGCGCGCAGGGCGCTTCACGCTACGAGGAGGATGC
GGGCAAGCGCCCCGAGATGGTGCTCGATACCGCGCGCGAGTTCCGCGCCGAGCGCTACGGGATCGACATCTTCAAGATGG
AAAGCCCGATCGCCGCCCACAGCGTGCCCGATCCGGATGCGGCCGAATCGGCGGCCTGTCAGCGCTGGTTCGACGAACTG
GGCCGCACGCTCGATCGCCCCTGGGTCATGCTGTCGGCCGGCGCGGGGATGGAACCCTTCCGGCGCATCGCGGCACATGC
TTTCCGTGCCGGGGCCAGCGGCTACCTCGCCGGACGCGCCATCTGGTGGCCGAGCTTCGAAGCCGCCTTTCCTGACTGGG
AGTCCATGCGCGCCGGCGTCCTGCGCGATGGCGTGCCCTACGCGCGGATGCTGCATGCACTGCTCGAGCGCACCGGCACG
CCCTGGAGCGCCTGCCGCGCGTTTGCGCACGGCATCGAACTGGCGGACGCCAGCGCCGATTTCTACGCCCGCTATCCGGC
CGCCTGA

Upstream 100 bases:

>100_bases
AGGCAAAACCTGCGGCTTGGCAACTGGGAAATCGCCCGGGAAAATGAAATAAAAATATCTCTAGAATCACGAACGACATA
AACGTTCCATTTCAAAACCC

Downstream 100 bases:

>100_bases
GCGCGATGGACTACACCTTCCAGTTCGGTTCGGTGTGGGCTGCGCTGCCCCGACTCGCGCAGGGCGCGCAATTGACGGTG
CTGCTATCGCTCGCCGCCAT

Product: tagatose-bisphosphate aldolase

Products: NA

Alternate protein names: D-tagatose-1,6-bisphosphate aldolase 1; Tagatose-bisphosphate aldolase 1 [H]

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MQISAGKLWSMRRLADERGFFKMTAVDQRPGVEALVRQRRGAGGAGACLFEDVGQVKRVLIETLSPWSSAMLLDPGYAYP
RAALQADPRKGLLLTYEQWDCEETPGGRKTFAYRDWSVEKIKRLGADGVKLMLWWRPDASKDVKLHQRALVEQVGRDCRR
HDIAFLLEPLLYPPGSAQGASRYEEDAGKRPEMVLDTAREFRAERYGIDIFKMESPIAAHSVPDPDAAESAACQRWFDEL
GRTLDRPWVMLSAGAGMEPFRRIAAHAFRAGASGYLAGRAIWWPSFEAAFPDWESMRAGVLRDGVPYARMLHALLERTGT
PWSACRAFAHGIELADASADFYARYPAA

Sequences:

>Translated_348_residues
MQISAGKLWSMRRLADERGFFKMTAVDQRPGVEALVRQRRGAGGAGACLFEDVGQVKRVLIETLSPWSSAMLLDPGYAYP
RAALQADPRKGLLLTYEQWDCEETPGGRKTFAYRDWSVEKIKRLGADGVKLMLWWRPDASKDVKLHQRALVEQVGRDCRR
HDIAFLLEPLLYPPGSAQGASRYEEDAGKRPEMVLDTAREFRAERYGIDIFKMESPIAAHSVPDPDAAESAACQRWFDEL
GRTLDRPWVMLSAGAGMEPFRRIAAHAFRAGASGYLAGRAIWWPSFEAAFPDWESMRAGVLRDGVPYARMLHALLERTGT
PWSACRAFAHGIELADASADFYARYPAA
>Mature_348_residues
MQISAGKLWSMRRLADERGFFKMTAVDQRPGVEALVRQRRGAGGAGACLFEDVGQVKRVLIETLSPWSSAMLLDPGYAYP
RAALQADPRKGLLLTYEQWDCEETPGGRKTFAYRDWSVEKIKRLGADGVKLMLWWRPDASKDVKLHQRALVEQVGRDCRR
HDIAFLLEPLLYPPGSAQGASRYEEDAGKRPEMVLDTAREFRAERYGIDIFKMESPIAAHSVPDPDAAESAACQRWFDEL
GRTLDRPWVMLSAGAGMEPFRRIAAHAFRAGASGYLAGRAIWWPSFEAAFPDWESMRAGVLRDGVPYARMLHALLERTGT
PWSACRAFAHGIELADASADFYARYPAA

Specific function: Unknown

COG id: COG3684

COG function: function code G; Tagatose-1,6-bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase lacD family [H]

Homologues:

Organism=Escherichia coli, GI1790314, Length=299, Percent_Identity=27.4247491638796, Blast_Score=94, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR002915
- InterPro:   IPR005927 [H]

Pfam domain/function: PF01791 DeoC [H]

EC number: =4.1.2.40 [H]

Molecular weight: Translated: 38971; Mature: 38971

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQISAGKLWSMRRLADERGFFKMTAVDQRPGVEALVRQRRGAGGAGACLFEDVGQVKRVL
CCCCCHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
IETLSPWSSAMLLDPGYAYPRAALQADPRKGLLLTYEQWDCEETPGGRKTFAYRDWSVEK
HHHHCCCCCEEEECCCCCCCHHHHCCCCCCCEEEEEECCCCCCCCCCCEEEEECCCCHHH
IKRLGADGVKLMLWWRPDASKDVKLHQRALVEQVGRDCRRHDIAFLLEPLLYPPGSAQGA
HHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
SRYEEDAGKRPEMVLDTAREFRAERYGIDIFKMESPIAAHSVPDPDAAESAACQRWFDEL
HHHHHHCCCCCHHHHHHHHHHHHHHHCCEEEEECCCCHHCCCCCCCHHHHHHHHHHHHHH
GRTLDRPWVMLSAGAGMEPFRRIAAHAFRAGASGYLAGRAIWWPSFEAAFPDWESMRAGV
HHHHCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCEEECCCHHCCCCCHHHHHHHH
LRDGVPYARMLHALLERTGTPWSACRAFAHGIELADASADFYARYPAA
HHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MQISAGKLWSMRRLADERGFFKMTAVDQRPGVEALVRQRRGAGGAGACLFEDVGQVKRVL
CCCCCHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
IETLSPWSSAMLLDPGYAYPRAALQADPRKGLLLTYEQWDCEETPGGRKTFAYRDWSVEK
HHHHCCCCCEEEECCCCCCCHHHHCCCCCCCEEEEEECCCCCCCCCCCEEEEECCCCHHH
IKRLGADGVKLMLWWRPDASKDVKLHQRALVEQVGRDCRRHDIAFLLEPLLYPPGSAQGA
HHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
SRYEEDAGKRPEMVLDTAREFRAERYGIDIFKMESPIAAHSVPDPDAAESAACQRWFDEL
HHHHHHCCCCCHHHHHHHHHHHHHHHCCEEEEECCCCHHCCCCCCCHHHHHHHHHHHHHH
GRTLDRPWVMLSAGAGMEPFRRIAAHAFRAGASGYLAGRAIWWPSFEAAFPDWESMRAGV
HHHHCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCEEECCCHHCCCCCHHHHHHHH
LRDGVPYARMLHALLERTGTPWSACRAFAHGIELADASADFYARYPAA
HHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1400164; 12397186 [H]