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The map label for this gene is adrA [H]

Identifier: 120613376

GI number: 120613376

Start: 5295802

End: 5296935

Strand: Direct

Name: adrA [H]

Synonym: Aave_4748

Alternate gene names: 120613376

Gene position: 5295802-5296935 (Clockwise)

Preceding gene: 120613374

Following gene: 120613378

Centisome position: 98.94

GC content: 69.31

Gene sequence:

>1134_bases
ATGCCGCCGATGCCCCCCTCGCCCAACCCGCCCGCGTCCATGCCCACTCCGGAACGCACCGACCACTGGCTGGTGCGGAT
GAACCACCGCAACCGCACCTTCTTCTACGCCTTGCTGTTCCTGGCGCTGGGGGCGCATTTCCGGCACACGGGCGCCGGCC
CGGCGGTCTGGGTCGTTCTGGTCGTGCAGTTCCTCGTCTATCCGCAGCTCGCCTACTGGACGGCCCGCAGCGCGCCGCGC
CAGGCGAAGGCGGAACTGCGCAACATGGTGGTGGACAACCTCTTCGGCGGACTCTGGGCGGGCCTGCTGGGCATGCCGGT
CTGGATCACCTTCACCCTGTTCATCGGCAACTGCATCAACGTCGTCGCGTTCCACGGCTATCCCGGCCTGCTGCGCCTCG
TGGCCGCCATGGGCTGCGGCCTCCTGGGCGGACTCGTCCTGTATGGAGACCGCCCGCTGCACCCGGACATCGACACGGCC
ACGTCGCTGCTGTGCATCCTGGCGCTCACCCTGTTCCTCACGGTGTTCGCGCACACCAGCTACCGGCGGGCGATGGAACA
ACAGAAGAGCAACGACAGGCTGCGCGAGCAATTCGAGGAAATCCGGGCGCTGCAGGACCAGTTGCAGGAACAGGCCGTGC
GCGACCCGCTCACCGGCCTCTACAACCGGCGCCACCTCGACGCCACGCTCGCGTCCGAGATCGCGCGCTGCGGTGCCCAG
GGCCTGCCCCTGTCCCTGATGATGATCGACATCGACCATTTCAAGCGCATCAACGACACCCACGGCCATGCCGCGGGCGA
TGCCATGCTGCAGGCCCTGGCGCAACTGCTGCAGCGCCACGTGCGCGTGCGGGATCTGGCCTGCCGGCTCGGCGGCGAGG
AATTCGTGCTGCTGCTGCCGGAAACACCGCTCGCGGTGGCCCGGGAGCGTGCCGAGGCACTGCGCGAGGCCTTCGAGGCT
CTCCAGGTGCGCCACGACCCCGAGGTGCTGTCCGCCACCCTGTCCTGCGGGGTCGCGGCGTTCCCGCAGCACGCGCGCCA
GCCGCTGGCGCTCACGGCAAGCGCCGACGAAGCGCTGTACGCCGCCAAGATGCAGGGGCGCAACCGCGTGGTGGTACAGG
ACGAACCCGCCTGA

Upstream 100 bases:

>100_bases
GGAAGGCAACACTGCAGCTTTCCGGAAAACTGCCGATAAGGGGGATCTACTGTCCAGTTCACCATCCATTCGCCCTCCCC
TGCGGGCCTGCCCGGACGCC

Downstream 100 bases:

>100_bases
GACGGCGGCGCCGGGTGCAGTACGGCACGGAGTCCCGCTGCGCGGAATCGCTCATTCCTTCTTGCGCAGGTGGACCGACC
GGGGTCCGCGCAGCGTCTCG

Product: diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 377; Mature: 376

Protein sequence:

>377_residues
MPPMPPSPNPPASMPTPERTDHWLVRMNHRNRTFFYALLFLALGAHFRHTGAGPAVWVVLVVQFLVYPQLAYWTARSAPR
QAKAELRNMVVDNLFGGLWAGLLGMPVWITFTLFIGNCINVVAFHGYPGLLRLVAAMGCGLLGGLVLYGDRPLHPDIDTA
TSLLCILALTLFLTVFAHTSYRRAMEQQKSNDRLREQFEEIRALQDQLQEQAVRDPLTGLYNRRHLDATLASEIARCGAQ
GLPLSLMMIDIDHFKRINDTHGHAAGDAMLQALAQLLQRHVRVRDLACRLGGEEFVLLLPETPLAVARERAEALREAFEA
LQVRHDPEVLSATLSCGVAAFPQHARQPLALTASADEALYAAKMQGRNRVVVQDEPA

Sequences:

>Translated_377_residues
MPPMPPSPNPPASMPTPERTDHWLVRMNHRNRTFFYALLFLALGAHFRHTGAGPAVWVVLVVQFLVYPQLAYWTARSAPR
QAKAELRNMVVDNLFGGLWAGLLGMPVWITFTLFIGNCINVVAFHGYPGLLRLVAAMGCGLLGGLVLYGDRPLHPDIDTA
TSLLCILALTLFLTVFAHTSYRRAMEQQKSNDRLREQFEEIRALQDQLQEQAVRDPLTGLYNRRHLDATLASEIARCGAQ
GLPLSLMMIDIDHFKRINDTHGHAAGDAMLQALAQLLQRHVRVRDLACRLGGEEFVLLLPETPLAVARERAEALREAFEA
LQVRHDPEVLSATLSCGVAAFPQHARQPLALTASADEALYAAKMQGRNRVVVQDEPA
>Mature_376_residues
PPMPPSPNPPASMPTPERTDHWLVRMNHRNRTFFYALLFLALGAHFRHTGAGPAVWVVLVVQFLVYPQLAYWTARSAPRQ
AKAELRNMVVDNLFGGLWAGLLGMPVWITFTLFIGNCINVVAFHGYPGLLRLVAAMGCGLLGGLVLYGDRPLHPDIDTAT
SLLCILALTLFLTVFAHTSYRRAMEQQKSNDRLREQFEEIRALQDQLQEQAVRDPLTGLYNRRHLDATLASEIARCGAQG
LPLSLMMIDIDHFKRINDTHGHAAGDAMLQALAQLLQRHVRVRDLACRLGGEEFVLLLPETPLAVARERAEALREAFEAL
QVRHDPEVLSATLSCGVAAFPQHARQPLALTASADEALYAAKMQGRNRVVVQDEPA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1786584, Length=325, Percent_Identity=32.3076923076923, Blast_Score=144, Evalue=8e-36,
Organism=Escherichia coli, GI1787262, Length=164, Percent_Identity=39.6341463414634, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI145693134, Length=178, Percent_Identity=39.8876404494382, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI87081881, Length=172, Percent_Identity=41.2790697674419, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI87082007, Length=185, Percent_Identity=38.3783783783784, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI1788381, Length=179, Percent_Identity=34.6368715083799, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1788085, Length=166, Percent_Identity=35.5421686746988, Blast_Score=95, Evalue=9e-21,
Organism=Escherichia coli, GI1787816, Length=169, Percent_Identity=36.6863905325444, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787802, Length=173, Percent_Identity=34.1040462427746, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI87081974, Length=166, Percent_Identity=30.7228915662651, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788956, Length=192, Percent_Identity=32.2916666666667, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1787541, Length=174, Percent_Identity=29.3103448275862, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR007894 [H]

Pfam domain/function: PF00990 GGDEF; PF05230 MASE2 [H]

EC number: NA

Molecular weight: Translated: 41870; Mature: 41739

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPMPPSPNPPASMPTPERTDHWLVRMNHRNRTFFYALLFLALGAHFRHTGAGPAVWVVL
CCCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
VVQFLVYPQLAYWTARSAPRQAKAELRNMVVDNLFGGLWAGLLGMPVWITFTLFIGNCIN
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVAFHGYPGLLRLVAAMGCGLLGGLVLYGDRPLHPDIDTATSLLCILALTLFLTVFAHTS
HHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
YRRAMEQQKSNDRLREQFEEIRALQDQLQEQAVRDPLTGLYNRRHLDATLASEIARCGAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GLPLSLMMIDIDHFKRINDTHGHAAGDAMLQALAQLLQRHVRVRDLACRLGGEEFVLLLP
CCCCEEEEEEHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
ETPLAVARERAEALREAFEALQVRHDPEVLSATLSCGVAAFPQHARQPLALTASADEALY
CCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHCCCCEEEECCCHHHHH
AAKMQGRNRVVVQDEPA
HHHHCCCCEEEEECCCC
>Mature Secondary Structure 
PPMPPSPNPPASMPTPERTDHWLVRMNHRNRTFFYALLFLALGAHFRHTGAGPAVWVVL
CCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
VVQFLVYPQLAYWTARSAPRQAKAELRNMVVDNLFGGLWAGLLGMPVWITFTLFIGNCIN
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVAFHGYPGLLRLVAAMGCGLLGGLVLYGDRPLHPDIDTATSLLCILALTLFLTVFAHTS
HHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
YRRAMEQQKSNDRLREQFEEIRALQDQLQEQAVRDPLTGLYNRRHLDATLASEIARCGAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GLPLSLMMIDIDHFKRINDTHGHAAGDAMLQALAQLLQRHVRVRDLACRLGGEEFVLLLP
CCCCEEEEEEHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
ETPLAVARERAEALREAFEALQVRHDPEVLSATLSCGVAAFPQHARQPLALTASADEALY
CCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHCCCCEEEECCCHHHHH
AAKMQGRNRVVVQDEPA
HHHHCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]