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The map label for this gene is qseD [H]

Identifier: 120613329

GI number: 120613329

Start: 5241272

End: 5242216

Strand: Direct

Name: qseD [H]

Synonym: Aave_4698

Alternate gene names: 120613329

Gene position: 5241272-5242216 (Clockwise)

Preceding gene: 120613328

Following gene: 120613330

Centisome position: 97.92

GC content: 73.65

Gene sequence:

>945_bases
ATGCAGCTCAAATGGATGGAAGACTTCATCGCGCTGGCCCAGGAACGCAGTTTCACCCGCGCAGCCGAACTGCGGCACGT
CACGCATCCCGCATTCGGGCGGCGCATCCGGGCACTGGAGGCCTGGGCCGGCACGGCCCTGGTGGAGCGCGGCGGTGCGC
AGGAGCAGGACGCCGGCCATCCCCGTGGCCGCGGCGGTGCGGGCGGCCCGGTGCGGCTGACGGCGGCGGGAACGGCCTTT
CTCGCGACGGCGGAGCAGCTCGCGCGCGAGCTCTCCCAATCGCAGGGGGAGCTGCGCGCCATCGCCGGCCGGCAGGCGCG
CTCGGTCACCATCGCCACGGGCCGCACGCTGGCGCGCACGGCGCTGGCGGACGCCCTCCCGCGGCTGCGGGCGGTCCTGC
AGTCCGCAGAGCTGCGGGTAGTGACCAACGGACTGGCGCAGACGGTGGAGATGCTGGAGCGCGGCGAGGCGGATTTCTGG
CTGGGCTACCACCATGCCGCGCTCGAAGTGCGGCTGGACGGGCGCTCCTACGCCCACGCCACGCTCGCGTCCGACCGGCT
CGTGCCCGTGTCGCGCGCGGATTCCCAGGGCCTGCCGCGGCATGCACTGGCTTCGTCCGGCTCCGCGGTGCCTTACCTCG
CCTACGCCGACACGCTGGCGCTCGGCCGGCTGGTGGAAGACCTGCTGGCGCGGCACCCGCTGGCGCCCCGGCTGCGCCGC
ATCATCGAATGCGACTCGGCCGACGCGCAATACGAGTACGTGCACCGCGGACTGGGCGTTGCCTGGCTGCCCTGGTCCAT
GGTGCGGGCCGACTGCCAGGCCGGACGGCTGGCTGCGGCCGGTGAACGCCGCCTGGAACTGCGTTTCGACGTTCGGCTGG
TCCGGCCCAAGCGCCGGCTCACCGATGCCGCCGAGGCGGCATGGCAGGCTTTCGTGCGCGCCTGA

Upstream 100 bases:

>100_bases
GTACGGCGGTGCAGCCGCATTGAGCTGCCCGTGCCGGCCATCCAGGGCCGCGGGGCCAGAAGGCTCCAGGCCGACACACT
CAACAGCGGTAGCACCTGTC

Downstream 100 bases:

>100_bases
CTGCCGGGCTGCACCCGCCGGTGGTGCCGGATCGGCACGGCTTCGTGCCCATTTGGCACCGTCTGCCTGCACGCGGGTCC
GACAATCGTGCCCACCCCCT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Quorum-sensing regulator protein D [H]

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MQLKWMEDFIALAQERSFTRAAELRHVTHPAFGRRIRALEAWAGTALVERGGAQEQDAGHPRGRGGAGGPVRLTAAGTAF
LATAEQLARELSQSQGELRAIAGRQARSVTIATGRTLARTALADALPRLRAVLQSAELRVVTNGLAQTVEMLERGEADFW
LGYHHAALEVRLDGRSYAHATLASDRLVPVSRADSQGLPRHALASSGSAVPYLAYADTLALGRLVEDLLARHPLAPRLRR
IIECDSADAQYEYVHRGLGVAWLPWSMVRADCQAGRLAAAGERRLELRFDVRLVRPKRRLTDAAEAAWQAFVRA

Sequences:

>Translated_314_residues
MQLKWMEDFIALAQERSFTRAAELRHVTHPAFGRRIRALEAWAGTALVERGGAQEQDAGHPRGRGGAGGPVRLTAAGTAF
LATAEQLARELSQSQGELRAIAGRQARSVTIATGRTLARTALADALPRLRAVLQSAELRVVTNGLAQTVEMLERGEADFW
LGYHHAALEVRLDGRSYAHATLASDRLVPVSRADSQGLPRHALASSGSAVPYLAYADTLALGRLVEDLLARHPLAPRLRR
IIECDSADAQYEYVHRGLGVAWLPWSMVRADCQAGRLAAAGERRLELRFDVRLVRPKRRLTDAAEAAWQAFVRA
>Mature_314_residues
MQLKWMEDFIALAQERSFTRAAELRHVTHPAFGRRIRALEAWAGTALVERGGAQEQDAGHPRGRGGAGGPVRLTAAGTAF
LATAEQLARELSQSQGELRAIAGRQARSVTIATGRTLARTALADALPRLRAVLQSAELRVVTNGLAQTVEMLERGEADFW
LGYHHAALEVRLDGRSYAHATLASDRLVPVSRADSQGLPRHALASSGSAVPYLAYADTLALGRLVEDLLARHPLAPRLRR
IIECDSADAQYEYVHRGLGVAWLPWSMVRADCQAGRLAAAGERRLELRFDVRLVRPKRRLTDAAEAAWQAFVRA

Specific function: Down-regulates expression of the flagellar regulon, decreasing motility [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790783, Length=309, Percent_Identity=25.5663430420712, Blast_Score=99, Evalue=2e-22,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34314; Mature: 34314

Theoretical pI: Translated: 10.64; Mature: 10.64

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLKWMEDFIALAQERSFTRAAELRHVTHPAFGRRIRALEAWAGTALVERGGAQEQDAGH
CCCHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PRGRGGAGGPVRLTAAGTAFLATAEQLARELSQSQGELRAIAGRQARSVTIATGRTLART
CCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCEEEEECCCHHHHH
ALADALPRLRAVLQSAELRVVTNGLAQTVEMLERGEADFWLGYHHAALEVRLDGRSYAHA
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEEEECCCCHHHH
TLASDRLVPVSRADSQGLPRHALASSGSAVPYLAYADTLALGRLVEDLLARHPLAPRLRR
HHCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHH
IIECDSADAQYEYVHRGLGVAWLPWSMVRADCQAGRLAAAGERRLELRFDVRLVRPKRRL
HHHCCCCCCHHHHHHHCCCEEECCHHHHHHHHHCCCCHHCCCCEEEEEEEEEEECCHHHH
TDAAEAAWQAFVRA
HHHHHHHHHHHHCC
>Mature Secondary Structure
MQLKWMEDFIALAQERSFTRAAELRHVTHPAFGRRIRALEAWAGTALVERGGAQEQDAGH
CCCHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PRGRGGAGGPVRLTAAGTAFLATAEQLARELSQSQGELRAIAGRQARSVTIATGRTLART
CCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCEEEEECCCHHHHH
ALADALPRLRAVLQSAELRVVTNGLAQTVEMLERGEADFWLGYHHAALEVRLDGRSYAHA
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEEEECCCCHHHH
TLASDRLVPVSRADSQGLPRHALASSGSAVPYLAYADTLALGRLVEDLLARHPLAPRLRR
HHCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHH
IIECDSADAQYEYVHRGLGVAWLPWSMVRADCQAGRLAAAGERRLELRFDVRLVRPKRRL
HHHCCCCCCHHHHHHHCCCEEECCHHHHHHHHHCCCCHHCCCCEEEEEEEEEEECCHHHH
TDAAEAAWQAFVRA
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 7876157 [H]