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The map label for this gene is corA [H]

Identifier: 120613205

GI number: 120613205

Start: 5089261

End: 5090247

Strand: Direct

Name: corA [H]

Synonym: Aave_4572

Alternate gene names: 120613205

Gene position: 5089261-5090247 (Clockwise)

Preceding gene: 120613204

Following gene: 120613212

Centisome position: 95.08

GC content: 62.92

Gene sequence:

>987_bases
ATGCTCAACATTTTCACGCTCGCCAACGGCCGCCTCGTCCAGGAAGAGATCGAATCCCTGGAAGACCTCGCCCGCTTCCA
GCCGATCTGGGTGGACCTGGAATCGCCCACGCTCGAAGAGAAGCGCTGGATCAAGCAGCACTACGGCCTGCAGATCCCCG
CGGACGCGATGGACGAGGACATCGAGGAATCCGCCCGCTTCTACGAGGAAGACAACGGCGAGCTGCATATCCGCAGCGAC
TTCCTGATCGACGACGAGGACAACCCCCGCTCGGTGCGCGTGGCGTTCATCCTCAACCTGGTCAACGACACGCTCAAGAG
CAAGGGCGTGCTGTTCTCCATCCATGACGAGGACCTGCCCGTCTTCCGGCTGCTGCGCATGCGCGCGCGCCGGGCGCCCG
GCCTGATCGAGGACGCCAAGGAAGTGCTGCTCAAGCTCTTCGACCTGGACGCGGAATACTCCGCCGACACGCTCGAGGGC
ATCTATGACGAACTGAAGGAAGTGAGCACCCAGGTGCTGGCGGGCGACGTGACGGACGCCCGCGCCGGCGAGGTGCTGGC
CGCCATCGCGCGCCAGGAGGACCTGAACGGCCGCATCCGCCGCAACGTGATGGACACGCGCCGCGCCGTGAGCTTCATGA
TGCGCAGCAAGATGCTGAACGCCGAGCAGTTCGAGGACGCGCGGCAGATCCTGCGCGACATCGAGTCGCTGGACAACCAC
ACGGCGTTCCTGTTCGACAAGATCAACTTCCTGATGGATGCCACGGTCGGCTTCATCAACATCAACCAGAACAAGATCAT
CAAGATCTTCTCGGTGGCGAGCGTGGCGCTGCTGCCGCCCACGCTCATCGCGAGCGTGTACGGGATGAACTTCCAGTACA
TGCCGGAATTGCAGTGGACCTACGGCTACGCCTACGGCATCGCGCTGATGGTGGCGAGCGCGGTGGGACCCATGTGGTAT
TTCCGTAAGCGCGGATGGTTGAAGTGA

Upstream 100 bases:

>100_bases
TCAACTCCCGGCATGCCCAGGGCTTTCGGGGGGTTGAAAGCACCCTTGCGTCATCCCTTCGCCAACGGCGCCGCCGCGCC
AACCCACCGGGAACGAGCCC

Downstream 100 bases:

>100_bases
ATCCCCGCTGAGGCGCTGCGCGCGCTCCCCCCTGGAGGAACGACGCCGGTGGCGCGGCGGAGCCGGTGGCGCGGCGTATG
CCGGCCTGGGCCGCGCCTCC

Product: magnesium and cobalt transport protein CorA

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MLNIFTLANGRLVQEEIESLEDLARFQPIWVDLESPTLEEKRWIKQHYGLQIPADAMDEDIEESARFYEEDNGELHIRSD
FLIDDEDNPRSVRVAFILNLVNDTLKSKGVLFSIHDEDLPVFRLLRMRARRAPGLIEDAKEVLLKLFDLDAEYSADTLEG
IYDELKEVSTQVLAGDVTDARAGEVLAAIARQEDLNGRIRRNVMDTRRAVSFMMRSKMLNAEQFEDARQILRDIESLDNH
TAFLFDKINFLMDATVGFININQNKIIKIFSVASVALLPPTLIASVYGMNFQYMPELQWTYGYAYGIALMVASAVGPMWY
FRKRGWLK

Sequences:

>Translated_328_residues
MLNIFTLANGRLVQEEIESLEDLARFQPIWVDLESPTLEEKRWIKQHYGLQIPADAMDEDIEESARFYEEDNGELHIRSD
FLIDDEDNPRSVRVAFILNLVNDTLKSKGVLFSIHDEDLPVFRLLRMRARRAPGLIEDAKEVLLKLFDLDAEYSADTLEG
IYDELKEVSTQVLAGDVTDARAGEVLAAIARQEDLNGRIRRNVMDTRRAVSFMMRSKMLNAEQFEDARQILRDIESLDNH
TAFLFDKINFLMDATVGFININQNKIIKIFSVASVALLPPTLIASVYGMNFQYMPELQWTYGYAYGIALMVASAVGPMWY
FRKRGWLK
>Mature_328_residues
MLNIFTLANGRLVQEEIESLEDLARFQPIWVDLESPTLEEKRWIKQHYGLQIPADAMDEDIEESARFYEEDNGELHIRSD
FLIDDEDNPRSVRVAFILNLVNDTLKSKGVLFSIHDEDLPVFRLLRMRARRAPGLIEDAKEVLLKLFDLDAEYSADTLEG
IYDELKEVSTQVLAGDVTDARAGEVLAAIARQEDLNGRIRRNVMDTRRAVSFMMRSKMLNAEQFEDARQILRDIESLDNH
TAFLFDKINFLMDATVGFININQNKIIKIFSVASVALLPPTLIASVYGMNFQYMPELQWTYGYAYGIALMVASAVGPMWY
FRKRGWLK

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=328, Percent_Identity=43.9024390243902, Blast_Score=264, Evalue=7e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 37728; Mature: 37728

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNIFTLANGRLVQEEIESLEDLARFQPIWVDLESPTLEEKRWIKQHYGLQIPADAMDED
CEEEEEECCCCCHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHCCCCCCHHHHHHH
IEESARFYEEDNGELHIRSDFLIDDEDNPRSVRVAFILNLVNDTLKSKGVLFSIHDEDLP
HHHHHHHHHCCCCEEEEEECEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCH
VFRLLRMRARRAPGLIEDAKEVLLKLFDLDAEYSADTLEGIYDELKEVSTQVLAGDVTDA
HHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
RAGEVLAAIARQEDLNGRIRRNVMDTRRAVSFMMRSKMLNAEQFEDARQILRDIESLDNH
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCC
TAFLFDKINFLMDATVGFININQNKIIKIFSVASVALLPPTLIASVYGMNFQYMPELQWT
HHHHHHHHHHHHHCCEEEEEECCCCEEEHHHHHHHHHCCHHHHHHHHCCCCEECCCCCHH
YGYAYGIALMVASAVGPMWYFRKRGWLK
HHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLNIFTLANGRLVQEEIESLEDLARFQPIWVDLESPTLEEKRWIKQHYGLQIPADAMDED
CEEEEEECCCCCHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHCCCCCCHHHHHHH
IEESARFYEEDNGELHIRSDFLIDDEDNPRSVRVAFILNLVNDTLKSKGVLFSIHDEDLP
HHHHHHHHHCCCCEEEEEECEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCH
VFRLLRMRARRAPGLIEDAKEVLLKLFDLDAEYSADTLEGIYDELKEVSTQVLAGDVTDA
HHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
RAGEVLAAIARQEDLNGRIRRNVMDTRRAVSFMMRSKMLNAEQFEDARQILRDIESLDNH
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCC
TAFLFDKINFLMDATVGFININQNKIIKIFSVASVALLPPTLIASVYGMNFQYMPELQWT
HHHHHHHHHHHHHCCEEEEEECCCCEEEHHHHHHHHHCCHHHHHHHHCCCCEECCCCCHH
YGYAYGIALMVASAVGPMWYFRKRGWLK
HHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA