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The map label for this gene is ywlC [H]

Identifier: 120613197

GI number: 120613197

Start: 5081121

End: 5082131

Strand: Direct

Name: ywlC [H]

Synonym: Aave_4564

Alternate gene names: 120613197

Gene position: 5081121-5082131 (Clockwise)

Preceding gene: 120613196

Following gene: 120613198

Centisome position: 94.93

GC content: 72.8

Gene sequence:

>1011_bases
ATGATCCTCGACGGCCGGCTCCCCTCTTCCATCGATGCGGCGGCCCGGGCGCTGCGGGCCGGCAGGCTGCTGGGCCTGCC
CACGGAAACCGTGTACGGGCTCGCGGCGGATGCCGCCAGCGACGCGGCCGTGGCACAGATTTTCGAGGCCAAGGGCCGCC
CGAGCGACCACCCGCTGATCGTGCACGTGGCGGGGCCCGAAGGCATACCGCACTTCGCCGCGTCCGTTCCGCCTTTCGCC
GAGGCCCTGGTACGGGCTTTCTGGCCCGGCCCCCTGACATTGATCCTCCCGCGCCTGCCGGACAGGGCTGCCGCGGCGGC
CGGCGGCCAGAACAGCGTGGGCCTGCGCTGCCCGGCGCACCCGGTGGCGCAGGCCGTGCTCAAGGCCTGCGCATCGGACG
ATCCGGCGCTGGGCGGCCAGCCGGTGCATGGCGTGGCGGCGCCCAGCGCCAACCGCTTCGGCCGGGTGAGCCCCACCACC
GCGCAGCATGTGCAGGACGAGTTCGGGGAAGGCCTGGTGGTCCTCGACGGAGGGCCGTGCGCGGTGGGCATCGAATCGAC
CATCATCGACTGCACGCGCGGCGTGCCGGTGCTGCTGCGCCCGGGGGCCATCACCCGCGCCGAGATCGCCGCGGCCTGCG
GACTGTCGCCCCTGTCGAAGGAGGAACTGCCTTCGCACACGCCGCGGGCATCCGGCACGCTGGAAGCGCACTACGCGCCC
AGTGCCAAGGTACGGCTCATGGACGCCAAGGCACTGCAGGCCGGGCTGGAACTGCTGGGCGCCGAGGCACGCCACCTGGC
GGTGTATGCACGCGCCCGTCTTCGTTCGCCATCGCCCGGCGTGGTACTGCGCCGCATGCCGGAAGATGCCGCGGCCGCCG
CCCGGGAACTTTTCGCGGCCCTGCGGGACTTCGATGACGCGGGTGTGAAACTCATCTGGGTGGAAACACCGCCGGAGACA
CCGGACTGGGAAGGCGTGAGGGACCGCCTGCAGCGGGCAGCCGCCGCCTGA

Upstream 100 bases:

>100_bases
GGCCACCTGAACGTCACCGCGCCCACCGCGGAAGCCGCACGCGCCACGGCGCTGCAGGCCGCCGCGCTGCTGGGCATCGC
CGCGTTCTGAGGCCACCGCC

Downstream 100 bases:

>100_bases
ATTCGCGGGACGCCTCGGCGACACCCCCGGTTGCAAAGCCTTACAGCGCCAGTCGTTACACTCTTGCTCAATTTTCCTGG
AGAACAACATATGGCAGCAA

Product: translation factor SUA5

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MILDGRLPSSIDAAARALRAGRLLGLPTETVYGLAADAASDAAVAQIFEAKGRPSDHPLIVHVAGPEGIPHFAASVPPFA
EALVRAFWPGPLTLILPRLPDRAAAAAGGQNSVGLRCPAHPVAQAVLKACASDDPALGGQPVHGVAAPSANRFGRVSPTT
AQHVQDEFGEGLVVLDGGPCAVGIESTIIDCTRGVPVLLRPGAITRAEIAAACGLSPLSKEELPSHTPRASGTLEAHYAP
SAKVRLMDAKALQAGLELLGAEARHLAVYARARLRSPSPGVVLRRMPEDAAAAARELFAALRDFDDAGVKLIWVETPPET
PDWEGVRDRLQRAAAA

Sequences:

>Translated_336_residues
MILDGRLPSSIDAAARALRAGRLLGLPTETVYGLAADAASDAAVAQIFEAKGRPSDHPLIVHVAGPEGIPHFAASVPPFA
EALVRAFWPGPLTLILPRLPDRAAAAAGGQNSVGLRCPAHPVAQAVLKACASDDPALGGQPVHGVAAPSANRFGRVSPTT
AQHVQDEFGEGLVVLDGGPCAVGIESTIIDCTRGVPVLLRPGAITRAEIAAACGLSPLSKEELPSHTPRASGTLEAHYAP
SAKVRLMDAKALQAGLELLGAEARHLAVYARARLRSPSPGVVLRRMPEDAAAAARELFAALRDFDDAGVKLIWVETPPET
PDWEGVRDRLQRAAAA
>Mature_336_residues
MILDGRLPSSIDAAARALRAGRLLGLPTETVYGLAADAASDAAVAQIFEAKGRPSDHPLIVHVAGPEGIPHFAASVPPFA
EALVRAFWPGPLTLILPRLPDRAAAAAGGQNSVGLRCPAHPVAQAVLKACASDDPALGGQPVHGVAAPSANRFGRVSPTT
AQHVQDEFGEGLVVLDGGPCAVGIESTIIDCTRGVPVLLRPGAITRAEIAAACGLSPLSKEELPSHTPRASGTLEAHYAP
SAKVRLMDAKALQAGLELLGAEARHLAVYARARLRSPSPGVVLRRMPEDAAAAARELFAALRDFDDAGVKLIWVETPPET
PDWEGVRDRLQRAAAA

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Escherichia coli, GI2367210, Length=171, Percent_Identity=28.0701754385965, Blast_Score=61, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17537239, Length=190, Percent_Identity=30, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6321269, Length=397, Percent_Identity=32.4937027707809, Blast_Score=163, Evalue=3e-41,
Organism=Drosophila melanogaster, GI78707274, Length=111, Percent_Identity=32.4324324324324, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 34840; Mature: 34840

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILDGRLPSSIDAAARALRAGRLLGLPTETVYGLAADAASDAAVAQIFEAKGRPSDHPLI
CEECCCCCCHHHHHHHHHHHCCEECCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCEE
VHVAGPEGIPHFAASVPPFAEALVRAFWPGPLTLILPRLPDRAAAAAGGQNSVGLRCPAH
EEECCCCCCCHHHCCCCHHHHHHHHHHCCCCCEEEECCCCCHHHHHCCCCCCCCCCCCCH
PVAQAVLKACASDDPALGGQPVHGVAAPSANRFGRVSPTTAQHVQDEFGEGLVVLDGGPC
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEECCCCE
AVGIESTIIDCTRGVPVLLRPGAITRAEIAAACGLSPLSKEELPSHTPRASGTLEAHYAP
EECHHHHHHHHCCCCCEEECCCCCHHHHHHHHHCCCCCCHHHCCCCCCCCCCCEEEEECC
SAKVRLMDAKALQAGLELLGAEARHLAVYARARLRSPSPGVVLRRMPEDAAAAARELFAA
CCEEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHH
LRDFDDAGVKLIWVETPPETPDWEGVRDRLQRAAAA
HHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MILDGRLPSSIDAAARALRAGRLLGLPTETVYGLAADAASDAAVAQIFEAKGRPSDHPLI
CEECCCCCCHHHHHHHHHHHCCEECCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCEE
VHVAGPEGIPHFAASVPPFAEALVRAFWPGPLTLILPRLPDRAAAAAGGQNSVGLRCPAH
EEECCCCCCCHHHCCCCHHHHHHHHHHCCCCCEEEECCCCCHHHHHCCCCCCCCCCCCCH
PVAQAVLKACASDDPALGGQPVHGVAAPSANRFGRVSPTTAQHVQDEFGEGLVVLDGGPC
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEECCCCE
AVGIESTIIDCTRGVPVLLRPGAITRAEIAAACGLSPLSKEELPSHTPRASGTLEAHYAP
EECHHHHHHHHCCCCCEEECCCCCHHHHHHHHHCCCCCCHHHCCCCCCCCCCCEEEEECC
SAKVRLMDAKALQAGLELLGAEARHLAVYARARLRSPSPGVVLRRMPEDAAAAARELFAA
CCEEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHH
LRDFDDAGVKLIWVETPPETPDWEGVRDRLQRAAAA
HHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]