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The map label for this gene is rpoC

Identifier: 120613163

GI number: 120613163

Start: 5034124

End: 5038359

Strand: Reverse

Name: rpoC

Synonym: Aave_4530

Alternate gene names: 120613163

Gene position: 5038359-5034124 (Counterclockwise)

Preceding gene: 120613164

Following gene: 120613162

Centisome position: 94.13

GC content: 65.32

Gene sequence:

>4236_bases
ATGAAGTCTCTACTCGACCTGTTCAAGCAATTCACGCCGGACGAGCATTTCGATGCCATCCGCATCGGCATGGCGTCGCC
GGAGAAGATCCGTTCCTGGTCCTTCGGCGAGGTGAAGAAGCCCGAGACGATCAACTACCGCACGTTCAAGCCCGAGCGCG
ACGGCCTGTTCTGCGCCAAGATCTTCGGCCCGATCAAGGACTACGAGTGCCTGTGCGGCAAGTACAAGCGCCTGAAGCAC
CGCGGCGTGATCTGCGAGAAGTGCGGCGTGGAAGTGACCCAGACCAAGGTGCGCCGCGAGCGCATGGGCCACATCGACCT
GGCCGCGCCCTGCGCGCACATCTGGTTCCTGAAGTCGCTGCCGTCGCGTCTGGGCCTGGTGCTCGACATGACGCTGCGCG
ACATCGAGCGCGTGCTGTATTTCGAAGCCTACGTGGTGACCGACCCTGGCATGACCCCGCTGAAGAAGTTCGGGATCATG
TCCGAGGACGACCATGACGCGAAGCGCAAGGAATACGGCGACGAGTTCATCGCCAAGATGGGCGCCGAAGGCATCAAGGA
CCTGCTCGAAGGCATCGACATCGATCTGGAGATCGAGAAGCTGCGCGGCGACCTGACCGGCTCCGAAGTCAAGGTGAAGA
AGAACGCCAAGCGCCTGAAGGTGCTGGAAGCGTTCAAGAAGTCCGGCATCAAGCCCGAGTGGATGGTGCTGGACGTGCTG
CCCGTGCTGCCGCCGGACCTGCGTCCGCTGGTGCCGCTGGACGGCGGCCGCTTCGCGACCTCCGACCTGAACGACCTCTA
TCGCCGCGTCATCAACCGCAACTCGCGCCTGCGCCGCCTGCTGGAGCTGAAGGCTCCGGAGATCATCGCGCGCAACGAGA
AGCGGATGCTGCAGGAAGCCGTCGATTCGCTGCTGGACAACGGCCGCCGCGGCAAGGCGATGACGGGCGCGAACAAGCGC
GCGCTGAAGTCGCTGGCAGACATGATCAAGGGCAAGTCCGGCCGCTTCCGCCAGAACCTGCTGGGCAAGCGCGTCGACTA
CTCCGGCCGTTCCGTGATCACCGTGGGCCCGACGCTCAAGCTGCACCAGTGCGGCCTGCCGAAGCTGATGGCCCTGGAAC
TGTTCAAGCCCTTCATCTTCTCGCGCCTCGAGCAGATGGGCATCGCCACGACCATCAAGGCCGCGAAGAAGGAAGTCGAA
TCCGGCACGCCGGTGGTCTGGGACATCCTGGAAGAGGTCATCAAGGAGCATCCGGTCATGCTGAACCGTGCTCCGACGCT
GCACCGCCTGGGCATCCAGGCCTTCGAGCCGATCCTGATCGAAGGCAAGGCCATCCAGCTGCACCCGCTCGTCTGCGCGG
CCTTCAACGCCGACTTCGACGGTGACCAGATGGCCGTCCACGTGCCGCTGTCGGTGGAAGCGCAGATGGAAGCCCGCACG
CTGATGCTGGCCTCCAACAACGTGCTGTTCCCCGCTTCCGGCGAGCCTTCCATCGTGCCTTCGCAGGACGTGGTGCTGGG
CCTCTACCACGCCACCCGCGACAAGATCAACGGCAAGGGCGAGGGCCTGGTGTTCGCCGACACGGGCGAAGTCCAGCGCG
CGCTGGACGCCGGCCAGGTCGAGCTGCACGCCAAGATCAGCGTGCGCCTGACCGAATGGACCAAGGACAAGGCGTCCGGC
GAGTTCGTGCCCTCGACCTCGCTGGTCGATACGACCGTGGGCCGTGCGCTGCTGTCGGAGATCCTGCCCAAGGGCCTGCC
CTTCAGCAACATCAACAAGGCGCTGAAGAAGAAGGAAATCTCCAAGCTCATCAACGTGAGCTTCCGCAAGTGCGGCCTGA
AGGAAACCGTGGTGTTCGCGGACAAGCTGCTGCAGAACGGTTTCCGCCTGGCCACGCGCGCCGGCTTCTCCGTGGCGATC
GACGACATGCTCGTGCCGCCGCAGAAGACCGAGATCCTGGCCCGTGCCGAAGCCGAGGTGAAGGAGATCGAGCAGCAGTA
CGTCTCCGGTCTCGTGACCGCCGGCGAGCGCTACAACAAGGTGGTGGACATCTGGGGCAAGGCCGGCGACGACGTGTCCA
AGGTGATGATGGACCAGCTCAAGGTCGAGAAGACCACCGACCGCCACGGCAAGGAAGTGAACCAGGAGTCCTTCAACGCC
ATCTACATGATGGCCGACTCGGGCGCCCGGGGTTCCGCCGCGCAGATCCGCCAGCTGGCCGGCATGCGCGGCCTGATGGC
CAAGCCGGACGGCTCCATCATCGAGACCCCCATCACGGCGAACTTCCGTGAAGGCCTGAACGTGCTGCAGTACTTCATCT
CCACCCACGGCGCCCGGAAGGGCCTGGCGGATACGGCGCTGAAGACCGCGAACTCCGGCTACCTCACCCGCCGCCTGGTG
GACGTGACGCAGGATCTCGTGGTGACCGAAGAGGACTGCGGCACGACCAACGGTTCGGTGATGCGCGCCATCGTCGAGGG
CGGTGAAGTGATCGAGTCGCTGCGCGAGCGCGTGCTCGGCCGCTCCACGGCCGAAGAGGTGCTGCACCCCGAAACCCGCG
CCGTGCTGGTGCCGGCCGGCCAGATGCTGGACGAAGACACCCTCGAAGAGCTGGAAGCCGCCGGCGTGGACGAGGTGAAG
GTGCGCACCGCGCTGACCTGCGAAACCCGCTACGGCCTCTGCGCCAAGTGCTATGGCCGCGATCTGGGCCGTGGCGGCCT
GATCAACCTCGGCGAAGCCGTGGGTGTGATCGCTGCCCAGTCCATCGGCGAACCCGGCACGCAGTTGACCATGCGTACGT
TCCACATCGGTGGTGCCGCGTCGCGCGCCGCCATCGCATCGACCGTGGAAGCGAAGTCCAACGGCGTGATCGGCTTCAAC
GCCACGATGCGCTACGTGACCAACAGCAAGGGCGAGCTGGTGGTGATCGCGCGCTCGGGCGAGGTCATCATCCAGGACGA
GCACGGCCGCGAGCGCGAGCGCCACAAGGTGCCGTACGGCGCGACGCTGACGGTGAAGGCCGACCAGCAGGTCAAGGCCG
GCACGATCCTGGCCAACTGGGACCCGCTGACGCGACCGATCATCACGGAATTCGCCGGCCAGGTGAAGTTCGAGAACATC
GAGGAAGGCCTCACCGTCGCCAAGCAGGTGGACGATGTGACCGGCCTGTCCACGCTGGTCGTGATCGATCCGAAGCGCCG
TGGCTCCGCCAAGGTGGTGCGCCCGCAGGTGAAGCTCGTCGATGCGAACGGCGCCGAGGTGAAGATCCCCGGTACCGACC
ACTCGGTGACGATCGGCTTCCAGGTCGGCGCGCTGATCCAGGTGCGCGACGGCCAGGACGTGGGCCCCGGCGAAGTGCTG
GCGCGTATTCCGGTCGAAGGCCAGAAGACCCGCGACATCACCGGGGGTCTGCCGCGCGTGGCCGAGCTGTTCGAGGCCCG
CTCGCCCAAGGACAAGGGCATGCTGGCCGAGATCACCGGCACGGTGTCCTTCGGCAAGGAAACCAAGGGCAAGGTGCGCC
TGCAGATCACCGATCCGGACGGCAAGGTCTGGGACGAGCTGGTGCCCAAGGAAAAGAACGTGCTGGTCCACGAAGGCCAG
GTGGTGAACAAGGGCGAGCTGATCGTCGATGGTCCGGCCGATCCGCAGGACATCCTGCGCCTGCTGGGCATCGAGGAACT
GTCGCGCTACATCGTCGATGAAGTGCAGGACGTCTATCGCCTCCAGGGTGTGAAGATCAACGACAAGCACATCGAGGTGA
TCGTTCGCCAGATGCTGCGCCGCGTCGTGGTCGAGAACCCGGGCGAGTCGGGCTACATCGCCGGCGAGCAGGTCGAGCGT
TCGGAGATCCTCAACACCAACGAACAGCTGCAGTCCGAGGGCAAGATCCCCGCGACCTACAGCAACGTGCTGCTGGGTAT
CACGAAGGCATCGCTGTCCACCGATTCGTTCATCTCGGCCGCTTCCTTCCAGGAAACGACCCGCGTGCTCACCGAGGCTG
CCATCATGGGCAAGCGCGACGAGCTGCGTGGCCTGAAGGAGAACGTGATCGTGGGCCGCCTGATCCCGGCGGGTACCGGC
CTGGCCTACCACCAGGCACGCAAGGCCAAGGAAGCCATGGACGACGCCGAGCGCCGCGCCATCGCCGAGGCCGAGGCTGC
CGAGATGGCCACCACGGGCTCCGACGAAGCTCCGGAAGTCGAAGGCTCCGGCGTGGAAAGCGGTTCGGCCGAGTAA

Upstream 100 bases:

>100_bases
GGCATGCCCGAGTCGTTCAATGTGCTGGTCAAGGAAATCCGTTCCCTGGGCCTGGACATCGAACTGGAACGTTCTTAAGA
AGTACTAGGAGATAGGGTTT

Downstream 100 bases:

>100_bases
CCCACGGCCCTGCCTGCAAGCCGAACGGCCTGCCGCAACGCTCCCGCTCTGTCGCTCGTGGCAGGCCGGGAGCGTTTTTT
CAGGCGCGGAGGCTGCTGGC

Product: DNA-directed RNA polymerase subunit beta'

Products: NA

Alternate protein names: RNAP subunit beta'; RNA polymerase subunit beta'; Transcriptase subunit beta'

Number of amino acids: Translated: 1411; Mature: 1411

Protein sequence:

>1411_residues
MKSLLDLFKQFTPDEHFDAIRIGMASPEKIRSWSFGEVKKPETINYRTFKPERDGLFCAKIFGPIKDYECLCGKYKRLKH
RGVICEKCGVEVTQTKVRRERMGHIDLAAPCAHIWFLKSLPSRLGLVLDMTLRDIERVLYFEAYVVTDPGMTPLKKFGIM
SEDDHDAKRKEYGDEFIAKMGAEGIKDLLEGIDIDLEIEKLRGDLTGSEVKVKKNAKRLKVLEAFKKSGIKPEWMVLDVL
PVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNSRLRRLLELKAPEIIARNEKRMLQEAVDSLLDNGRRGKAMTGANKR
ALKSLADMIKGKSGRFRQNLLGKRVDYSGRSVITVGPTLKLHQCGLPKLMALELFKPFIFSRLEQMGIATTIKAAKKEVE
SGTPVVWDILEEVIKEHPVMLNRAPTLHRLGIQAFEPILIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSVEAQMEART
LMLASNNVLFPASGEPSIVPSQDVVLGLYHATRDKINGKGEGLVFADTGEVQRALDAGQVELHAKISVRLTEWTKDKASG
EFVPSTSLVDTTVGRALLSEILPKGLPFSNINKALKKKEISKLINVSFRKCGLKETVVFADKLLQNGFRLATRAGFSVAI
DDMLVPPQKTEILARAEAEVKEIEQQYVSGLVTAGERYNKVVDIWGKAGDDVSKVMMDQLKVEKTTDRHGKEVNQESFNA
IYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLV
DVTQDLVVTEEDCGTTNGSVMRAIVEGGEVIESLRERVLGRSTAEEVLHPETRAVLVPAGQMLDEDTLEELEAAGVDEVK
VRTALTCETRYGLCAKCYGRDLGRGGLINLGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAIASTVEAKSNGVIGFN
ATMRYVTNSKGELVVIARSGEVIIQDEHGRERERHKVPYGATLTVKADQQVKAGTILANWDPLTRPIITEFAGQVKFENI
EEGLTVAKQVDDVTGLSTLVVIDPKRRGSAKVVRPQVKLVDANGAEVKIPGTDHSVTIGFQVGALIQVRDGQDVGPGEVL
ARIPVEGQKTRDITGGLPRVAELFEARSPKDKGMLAEITGTVSFGKETKGKVRLQITDPDGKVWDELVPKEKNVLVHEGQ
VVNKGELIVDGPADPQDILRLLGIEELSRYIVDEVQDVYRLQGVKINDKHIEVIVRQMLRRVVVENPGESGYIAGEQVER
SEILNTNEQLQSEGKIPATYSNVLLGITKASLSTDSFISAASFQETTRVLTEAAIMGKRDELRGLKENVIVGRLIPAGTG
LAYHQARKAKEAMDDAERRAIAEAEAAEMATTGSDEAPEVEGSGVESGSAE

Sequences:

>Translated_1411_residues
MKSLLDLFKQFTPDEHFDAIRIGMASPEKIRSWSFGEVKKPETINYRTFKPERDGLFCAKIFGPIKDYECLCGKYKRLKH
RGVICEKCGVEVTQTKVRRERMGHIDLAAPCAHIWFLKSLPSRLGLVLDMTLRDIERVLYFEAYVVTDPGMTPLKKFGIM
SEDDHDAKRKEYGDEFIAKMGAEGIKDLLEGIDIDLEIEKLRGDLTGSEVKVKKNAKRLKVLEAFKKSGIKPEWMVLDVL
PVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNSRLRRLLELKAPEIIARNEKRMLQEAVDSLLDNGRRGKAMTGANKR
ALKSLADMIKGKSGRFRQNLLGKRVDYSGRSVITVGPTLKLHQCGLPKLMALELFKPFIFSRLEQMGIATTIKAAKKEVE
SGTPVVWDILEEVIKEHPVMLNRAPTLHRLGIQAFEPILIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSVEAQMEART
LMLASNNVLFPASGEPSIVPSQDVVLGLYHATRDKINGKGEGLVFADTGEVQRALDAGQVELHAKISVRLTEWTKDKASG
EFVPSTSLVDTTVGRALLSEILPKGLPFSNINKALKKKEISKLINVSFRKCGLKETVVFADKLLQNGFRLATRAGFSVAI
DDMLVPPQKTEILARAEAEVKEIEQQYVSGLVTAGERYNKVVDIWGKAGDDVSKVMMDQLKVEKTTDRHGKEVNQESFNA
IYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLV
DVTQDLVVTEEDCGTTNGSVMRAIVEGGEVIESLRERVLGRSTAEEVLHPETRAVLVPAGQMLDEDTLEELEAAGVDEVK
VRTALTCETRYGLCAKCYGRDLGRGGLINLGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAIASTVEAKSNGVIGFN
ATMRYVTNSKGELVVIARSGEVIIQDEHGRERERHKVPYGATLTVKADQQVKAGTILANWDPLTRPIITEFAGQVKFENI
EEGLTVAKQVDDVTGLSTLVVIDPKRRGSAKVVRPQVKLVDANGAEVKIPGTDHSVTIGFQVGALIQVRDGQDVGPGEVL
ARIPVEGQKTRDITGGLPRVAELFEARSPKDKGMLAEITGTVSFGKETKGKVRLQITDPDGKVWDELVPKEKNVLVHEGQ
VVNKGELIVDGPADPQDILRLLGIEELSRYIVDEVQDVYRLQGVKINDKHIEVIVRQMLRRVVVENPGESGYIAGEQVER
SEILNTNEQLQSEGKIPATYSNVLLGITKASLSTDSFISAASFQETTRVLTEAAIMGKRDELRGLKENVIVGRLIPAGTG
LAYHQARKAKEAMDDAERRAIAEAEAAEMATTGSDEAPEVEGSGVESGSAE
>Mature_1411_residues
MKSLLDLFKQFTPDEHFDAIRIGMASPEKIRSWSFGEVKKPETINYRTFKPERDGLFCAKIFGPIKDYECLCGKYKRLKH
RGVICEKCGVEVTQTKVRRERMGHIDLAAPCAHIWFLKSLPSRLGLVLDMTLRDIERVLYFEAYVVTDPGMTPLKKFGIM
SEDDHDAKRKEYGDEFIAKMGAEGIKDLLEGIDIDLEIEKLRGDLTGSEVKVKKNAKRLKVLEAFKKSGIKPEWMVLDVL
PVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNSRLRRLLELKAPEIIARNEKRMLQEAVDSLLDNGRRGKAMTGANKR
ALKSLADMIKGKSGRFRQNLLGKRVDYSGRSVITVGPTLKLHQCGLPKLMALELFKPFIFSRLEQMGIATTIKAAKKEVE
SGTPVVWDILEEVIKEHPVMLNRAPTLHRLGIQAFEPILIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSVEAQMEART
LMLASNNVLFPASGEPSIVPSQDVVLGLYHATRDKINGKGEGLVFADTGEVQRALDAGQVELHAKISVRLTEWTKDKASG
EFVPSTSLVDTTVGRALLSEILPKGLPFSNINKALKKKEISKLINVSFRKCGLKETVVFADKLLQNGFRLATRAGFSVAI
DDMLVPPQKTEILARAEAEVKEIEQQYVSGLVTAGERYNKVVDIWGKAGDDVSKVMMDQLKVEKTTDRHGKEVNQESFNA
IYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLV
DVTQDLVVTEEDCGTTNGSVMRAIVEGGEVIESLRERVLGRSTAEEVLHPETRAVLVPAGQMLDEDTLEELEAAGVDEVK
VRTALTCETRYGLCAKCYGRDLGRGGLINLGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAIASTVEAKSNGVIGFN
ATMRYVTNSKGELVVIARSGEVIIQDEHGRERERHKVPYGATLTVKADQQVKAGTILANWDPLTRPIITEFAGQVKFENI
EEGLTVAKQVDDVTGLSTLVVIDPKRRGSAKVVRPQVKLVDANGAEVKIPGTDHSVTIGFQVGALIQVRDGQDVGPGEVL
ARIPVEGQKTRDITGGLPRVAELFEARSPKDKGMLAEITGTVSFGKETKGKVRLQITDPDGKVWDELVPKEKNVLVHEGQ
VVNKGELIVDGPADPQDILRLLGIEELSRYIVDEVQDVYRLQGVKINDKHIEVIVRQMLRRVVVENPGESGYIAGEQVER
SEILNTNEQLQSEGKIPATYSNVLLGITKASLSTDSFISAASFQETTRVLTEAAIMGKRDELRGLKENVIVGRLIPAGTG
LAYHQARKAKEAMDDAERRAIAEAEAAEMATTGSDEAPEVEGSGVESGSAE

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family

Homologues:

Organism=Homo sapiens, GI4505939, Length=919, Percent_Identity=24.7007616974973, Blast_Score=176, Evalue=1e-43,
Organism=Homo sapiens, GI39725938, Length=850, Percent_Identity=24.3529411764706, Blast_Score=156, Evalue=1e-37,
Organism=Homo sapiens, GI103471997, Length=595, Percent_Identity=26.890756302521, Blast_Score=129, Evalue=2e-29,
Organism=Escherichia coli, GI2367335, Length=1395, Percent_Identity=67.4551971326165, Blast_Score=1890, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987878, Length=570, Percent_Identity=25.9649122807018, Blast_Score=144, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI25145495, Length=324, Percent_Identity=30.5555555555556, Blast_Score=137, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI71998295, Length=248, Percent_Identity=27.0161290322581, Blast_Score=89, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6320061, Length=915, Percent_Identity=24.1530054644809, Blast_Score=185, Evalue=5e-47,
Organism=Saccharomyces cerevisiae, GI6324690, Length=224, Percent_Identity=33.9285714285714, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI17530899, Length=497, Percent_Identity=25.5533199195171, Blast_Score=149, Evalue=2e-35,
Organism=Drosophila melanogaster, GI281360912, Length=512, Percent_Identity=22.65625, Blast_Score=110, Evalue=7e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPOC_ACIAC (A1TVS9)

Other databases:

- EMBL:   CP000512
- RefSeq:   YP_972841.1
- ProteinModelPortal:   A1TVS9
- STRING:   A1TVS9
- GeneID:   4667171
- GenomeReviews:   CP000512_GR
- KEGG:   aav:Aave_4530
- NMPDR:   fig|397945.5.peg.3899
- eggNOG:   COG0086
- HOGENOM:   HBG621785
- OMA:   FEARVPK
- PhylomeDB:   A1TVS9
- ProtClustDB:   PRK00566
- BioCyc:   AAVE397945:AAVE_4530-MONOMER
- HAMAP:   MF_01322
- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR007083
- InterPro:   IPR007081
- InterPro:   IPR012754
- SMART:   SM00663
- TIGRFAMs:   TIGR02386

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3; PF05000 RNA_pol_Rpb1_4; PF04998 RNA_pol_Rpb1_5

EC number: =2.7.7.6

Molecular weight: Translated: 154760; Mature: 154760

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSLLDLFKQFTPDEHFDAIRIGMASPEKIRSWSFGEVKKPETINYRTFKPERDGLFCAK
CCHHHHHHHHCCCCCCCCEEEECCCCHHHHCCCCCCCCCCCCCCCEEECCCCCCCEEEEH
IFGPIKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIDLAAPCAHIWFLKSL
HHCCCCHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
PSRLGLVLDMTLRDIERVLYFEAYVVTDPGMTPLKKFGIMSEDDHDAKRKEYGDEFIAKM
HHHHCEEHHHHHHHHHHHHHEEEEEEECCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHH
GAEGIKDLLEGIDIDLEIEKLRGDLTGSEVKVKKNAKRLKVLEAFKKSGIKPEWMVLDVL
CHHHHHHHHHCCCCCEEEHHHCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCCEEEEEEH
PVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNSRLRRLLELKAPEIIARNEKRMLQEA
HCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCHHHHCCHHHHHHHH
VDSLLDNGRRGKAMTGANKRALKSLADMIKGKSGRFRQNLLGKRVDYSGRSVITVGPTLK
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCEEEEECCCEE
LHQCGLPKLMALELFKPFIFSRLEQMGIATTIKAAKKEVESGTPVVWDILEEVIKEHPVM
EECCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCEE
LNRAPTLHRLGIQAFEPILIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSVEAQMEART
ECCCCCHHHHCHHHCCCEEEECCEEEECCEEEEEECCCCCCCCEEEEECCEECCCCCEEE
LMLASNNVLFPASGEPSIVPSQDVVLGLYHATRDKINGKGEGLVFADTGEVQRALDAGQV
EEEECCCEEEECCCCCCCCCCCCCEEEHHHHHHHCCCCCCCEEEEECCHHHHHHHCCCCE
ELHAKISVRLTEWTKDKASGEFVPSTSLVDTTVGRALLSEILPKGLPFSNINKALKKKEI
EEEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
SKLINVSFRKCGLKETVVFADKLLQNGFRLATRAGFSVAIDDMLVPPQKTEILARAEAEV
HHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHH
KEIEQQYVSGLVTAGERYNKVVDIWGKAGDDVSKVMMDQLKVEKTTDRHGKEVNQESFNA
HHHHHHHHHHHHHCCHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCE
IYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARK
EEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCCC
GLADTALKTANSGYLTRRLVDVTQDLVVTEEDCGTTNGSVMRAIVEGGEVIESLRERVLG
CHHHHHHHHCCCCHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
RSTAEEVLHPETRAVLVPAGQMLDEDTLEELEAAGVDEVKVRTALTCETRYGLCAKCYGR
CCHHHHHHCCCCCEEEECCHHHCCHHHHHHHHHCCCCCEEEEEEEEECCCCCHHHHHHCC
DLGRGGLINLGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAIASTVEAKSNGVIGFN
CCCCCCCEECHHHHHHHHHHHCCCCCCEEEEEEEEECCCHHHHHHHHHHHHCCCCEEEEC
ATMRYVTNSKGELVVIARSGEVIIQDEHGRERERHKVPYGATLTVKADQQVKAGTILANW
CEEEEEECCCCCEEEEEECCCEEEECCCCCCHHHHCCCCCCEEEEECCCCCCCCEEEECC
DPLTRPIITEFAGQVKFENIEEGLTVAKQVDDVTGLSTLVVIDPKRRGSAKVVRPQVKLV
CCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEECCEEEEE
DANGAEVKIPGTDHSVTIGFQVGALIQVRDGQDVGPGEVLARIPVEGQKTRDITGGLPRV
ECCCCEEEECCCCCEEEEEEEECEEEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCHHH
AELFEARSPKDKGMLAEITGTVSFGKETKGKVRLQITDPDGKVWDELVPKEKNVLVHEGQ
HHHHHCCCCCCCCCEEEEEEEEECCCCCCCEEEEEEECCCCHHHHHHCCCCCCEEEECCE
VVNKGELIVDGPADPQDILRLLGIEELSRYIVDEVQDVYRLQGVKINDKHIEVIVRQMLR
EECCCCEEEECCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHH
RVVVENPGESGYIAGEQVERSEILNTNEQLQSEGKIPATYSNVLLGITKASLSTDSFISA
HHHHCCCCCCCCCCCCHHHHHHHHCCCHHHHHCCCCCCCHHHHHEEEEHHCCCCHHHHHH
ASFQETTRVLTEAAIMGKRDELRGLKENVIVGRLIPAGTGLAYHQARKAKEAMDDAERRA
HHHHHHHHHHHHHHHHCCHHHHCCHHHCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
IAEAEAAEMATTGSDEAPEVEGSGVESGSAE
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKSLLDLFKQFTPDEHFDAIRIGMASPEKIRSWSFGEVKKPETINYRTFKPERDGLFCAK
CCHHHHHHHHCCCCCCCCEEEECCCCHHHHCCCCCCCCCCCCCCCEEECCCCCCCEEEEH
IFGPIKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIDLAAPCAHIWFLKSL
HHCCCCHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
PSRLGLVLDMTLRDIERVLYFEAYVVTDPGMTPLKKFGIMSEDDHDAKRKEYGDEFIAKM
HHHHCEEHHHHHHHHHHHHHEEEEEEECCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHH
GAEGIKDLLEGIDIDLEIEKLRGDLTGSEVKVKKNAKRLKVLEAFKKSGIKPEWMVLDVL
CHHHHHHHHHCCCCCEEEHHHCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCCEEEEEEH
PVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNSRLRRLLELKAPEIIARNEKRMLQEA
HCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCHHHHCCHHHHHHHH
VDSLLDNGRRGKAMTGANKRALKSLADMIKGKSGRFRQNLLGKRVDYSGRSVITVGPTLK
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCEEEEECCCEE
LHQCGLPKLMALELFKPFIFSRLEQMGIATTIKAAKKEVESGTPVVWDILEEVIKEHPVM
EECCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCEE
LNRAPTLHRLGIQAFEPILIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSVEAQMEART
ECCCCCHHHHCHHHCCCEEEECCEEEECCEEEEEECCCCCCCCEEEEECCEECCCCCEEE
LMLASNNVLFPASGEPSIVPSQDVVLGLYHATRDKINGKGEGLVFADTGEVQRALDAGQV
EEEECCCEEEECCCCCCCCCCCCCEEEHHHHHHHCCCCCCCEEEEECCHHHHHHHCCCCE
ELHAKISVRLTEWTKDKASGEFVPSTSLVDTTVGRALLSEILPKGLPFSNINKALKKKEI
EEEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
SKLINVSFRKCGLKETVVFADKLLQNGFRLATRAGFSVAIDDMLVPPQKTEILARAEAEV
HHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHH
KEIEQQYVSGLVTAGERYNKVVDIWGKAGDDVSKVMMDQLKVEKTTDRHGKEVNQESFNA
HHHHHHHHHHHHHCCHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCE
IYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARK
EEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCCC
GLADTALKTANSGYLTRRLVDVTQDLVVTEEDCGTTNGSVMRAIVEGGEVIESLRERVLG
CHHHHHHHHCCCCHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
RSTAEEVLHPETRAVLVPAGQMLDEDTLEELEAAGVDEVKVRTALTCETRYGLCAKCYGR
CCHHHHHHCCCCCEEEECCHHHCCHHHHHHHHHCCCCCEEEEEEEEECCCCCHHHHHHCC
DLGRGGLINLGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAIASTVEAKSNGVIGFN
CCCCCCCEECHHHHHHHHHHHCCCCCCEEEEEEEEECCCHHHHHHHHHHHHCCCCEEEEC
ATMRYVTNSKGELVVIARSGEVIIQDEHGRERERHKVPYGATLTVKADQQVKAGTILANW
CEEEEEECCCCCEEEEEECCCEEEECCCCCCHHHHCCCCCCEEEEECCCCCCCCEEEECC
DPLTRPIITEFAGQVKFENIEEGLTVAKQVDDVTGLSTLVVIDPKRRGSAKVVRPQVKLV
CCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEECCEEEEE
DANGAEVKIPGTDHSVTIGFQVGALIQVRDGQDVGPGEVLARIPVEGQKTRDITGGLPRV
ECCCCEEEECCCCCEEEEEEEECEEEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCHHH
AELFEARSPKDKGMLAEITGTVSFGKETKGKVRLQITDPDGKVWDELVPKEKNVLVHEGQ
HHHHHCCCCCCCCCEEEEEEEEECCCCCCCEEEEEEECCCCHHHHHHCCCCCCEEEECCE
VVNKGELIVDGPADPQDILRLLGIEELSRYIVDEVQDVYRLQGVKINDKHIEVIVRQMLR
EECCCCEEEECCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHH
RVVVENPGESGYIAGEQVERSEILNTNEQLQSEGKIPATYSNVLLGITKASLSTDSFISA
HHHHCCCCCCCCCCCCHHHHHHHHCCCHHHHHCCCCCCCHHHHHEEEEHHCCCCHHHHHH
ASFQETTRVLTEAAIMGKRDELRGLKENVIVGRLIPAGTGLAYHQARKAKEAMDDAERRA
HHHHHHHHHHHHHHHHCCHHHHCCHHHCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
IAEAEAAEMATTGSDEAPEVEGSGVESGSAE
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA