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The map label for this gene is rsmB [H]

Identifier: 120613161

GI number: 120613161

Start: 5031881

End: 5033266

Strand: Reverse

Name: rsmB [H]

Synonym: Aave_4528

Alternate gene names: 120613161

Gene position: 5033266-5031881 (Counterclockwise)

Preceding gene: 120613162

Following gene: 120613160

Centisome position: 94.03

GC content: 71.79

Gene sequence:

>1386_bases
ATGCCTGCATCCTCCCCGCATCCTTCCCCTTCCCGCCCGGATTCGCCCGGAGGGGCGATTCCCCTGTGGCGCCAGCTCGA
CGCGGTGGTGGATGCCGTGATGGCGGTGCGCGGCGGCCAGTCGGGTACCGCGGCCCTGGCGGCGGTGGACCCGGTGCTGC
GCGCGGGCGTTCAGGCGCTGTTCTTCGCGGTGCTGCGCCAGCTGGGCCGTGCGGAGGCGTTGCGGGCGCAACTGGCCCCG
CGGCGGCCCAAGCCGCGCGTGGATGCGCTGCTGTGCTCGACCCTGGCCCTGGGTTGGCAAGCAGGTGCCGCTCCCTATGA
GCCGTTCACGCTCGTGAACCAGGCGGTGGAGGCGGCCAAGCGCCATGCCGCCACGCGCGGGCAGGCAGCTTTCGTGAACG
CCTGTCTGCGCCGCTTCCTCCGCGAGCGCGATGCGCTGGTGGCCGCCACCGATTCGGATCCCGTCGCCCGGTGGAACCAT
CCCGCGTGGTGGATCGAGCGCCTGCGGAAGGACCATCCCGGCCATTGGGAGCAGATCCTGCGGGCCAACAACGCGCAGGC
CCCGATGGCATTGCGCATCCACCGGGGCAAGGTGGACATGGCGGGCTACCTGGCCGCGCTGGAGGCTGTGGGAATGAAGG
CCTGGCCGGCGACCGATACCGGTCTGGTCCTGGAGTCTCCGCAGCCCGTGCAGCGGCTTCCCGGGTTCGCCGACGGCCGG
GTTTCGGTGCAGGATCTCGCGGCCCAGCAGGCCGCGCCCCTGCTGCTGTCAGGCCTGGACCTGGGCCGGCCGCTGCGGGT
GCTGGATGCCTGCGCGGCGCCGGGCGGCAAGACCGCCCACCTGCTCGAGTATGCCGGTGCCGGATCGCCGGTCCACGTGA
CCGCGCTGGAGATCGACCCGCTGCGCAGCGCGCGCATCGGTGAAACGCTCCAGCGGCTGGGCCTGCGGGCGCAGGTGCTG
GTGGCCGATGCCGGGCGCCCGGAGGACTGGTGGCAGCAGGCCTGCGGCGGAGAGCCCTTCGATGCCATCCTGCTGGACGC
GCCCTGCACGGCGTCGGGCATCGTGCGGCGCCATCCGGATGTGCGCTGGCTGCGGCGCCCCGGGGACATCGCGCAGCTGG
CCGCCCAGCAGGCGCGGCTGCTGTCCACGCTCTGGCCGCTGCTGCGGCCGGGCGGGCGCATGCTGTATTGCACCTGTTCC
GTGTTCCGCGCGGAAGGCGATGACATGGTCCGGTCGTTTCTTGCGAACAACAATGATGCCCATTTGCTGCCTTCTCCCGG
ACATTTGCTGCCCCGGGATCCCGGTGATGGCGGCAGCGTCCGCGAGAATCCATCCCGTGAGCATGACGGTTTCTTCTACG
CACTCCTGGGCCGGCAGCCCGCCTGA

Upstream 100 bases:

>100_bases
CTGACGGCGTTTAGCGACATTCCCGCCCTGCAGCGGACGCCACGGGCGTCTTCGCAGGGTGGTTGTTTCCCATCCTTCGC
GCTTTCACGGCGCCCCTGAC

Downstream 100 bases:

>100_bases
AGCCATGCCGGCGCAGGGTTGGCGCGCGCGCCTGCAGGCCGCATGGGGCTCGGCCTGGCGCCATGCCTGCTGGACGCTCC
TGCTGTGCCTGGGGCTCTGG

Product: sun protein

Products: NA

Alternate protein names: 16S rRNA m5C967 methyltransferase; rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 461; Mature: 460

Protein sequence:

>461_residues
MPASSPHPSPSRPDSPGGAIPLWRQLDAVVDAVMAVRGGQSGTAALAAVDPVLRAGVQALFFAVLRQLGRAEALRAQLAP
RRPKPRVDALLCSTLALGWQAGAAPYEPFTLVNQAVEAAKRHAATRGQAAFVNACLRRFLRERDALVAATDSDPVARWNH
PAWWIERLRKDHPGHWEQILRANNAQAPMALRIHRGKVDMAGYLAALEAVGMKAWPATDTGLVLESPQPVQRLPGFADGR
VSVQDLAAQQAAPLLLSGLDLGRPLRVLDACAAPGGKTAHLLEYAGAGSPVHVTALEIDPLRSARIGETLQRLGLRAQVL
VADAGRPEDWWQQACGGEPFDAILLDAPCTASGIVRRHPDVRWLRRPGDIAQLAAQQARLLSTLWPLLRPGGRMLYCTCS
VFRAEGDDMVRSFLANNNDAHLLPSPGHLLPRDPGDGGSVRENPSREHDGFFYALLGRQPA

Sequences:

>Translated_461_residues
MPASSPHPSPSRPDSPGGAIPLWRQLDAVVDAVMAVRGGQSGTAALAAVDPVLRAGVQALFFAVLRQLGRAEALRAQLAP
RRPKPRVDALLCSTLALGWQAGAAPYEPFTLVNQAVEAAKRHAATRGQAAFVNACLRRFLRERDALVAATDSDPVARWNH
PAWWIERLRKDHPGHWEQILRANNAQAPMALRIHRGKVDMAGYLAALEAVGMKAWPATDTGLVLESPQPVQRLPGFADGR
VSVQDLAAQQAAPLLLSGLDLGRPLRVLDACAAPGGKTAHLLEYAGAGSPVHVTALEIDPLRSARIGETLQRLGLRAQVL
VADAGRPEDWWQQACGGEPFDAILLDAPCTASGIVRRHPDVRWLRRPGDIAQLAAQQARLLSTLWPLLRPGGRMLYCTCS
VFRAEGDDMVRSFLANNNDAHLLPSPGHLLPRDPGDGGSVRENPSREHDGFFYALLGRQPA
>Mature_460_residues
PASSPHPSPSRPDSPGGAIPLWRQLDAVVDAVMAVRGGQSGTAALAAVDPVLRAGVQALFFAVLRQLGRAEALRAQLAPR
RPKPRVDALLCSTLALGWQAGAAPYEPFTLVNQAVEAAKRHAATRGQAAFVNACLRRFLRERDALVAATDSDPVARWNHP
AWWIERLRKDHPGHWEQILRANNAQAPMALRIHRGKVDMAGYLAALEAVGMKAWPATDTGLVLESPQPVQRLPGFADGRV
SVQDLAAQQAAPLLLSGLDLGRPLRVLDACAAPGGKTAHLLEYAGAGSPVHVTALEIDPLRSARIGETLQRLGLRAQVLV
ADAGRPEDWWQQACGGEPFDAILLDAPCTASGIVRRHPDVRWLRRPGDIAQLAAQQARLLSTLWPLLRPGGRMLYCTCSV
FRAEGDDMVRSFLANNNDAHLLPSPGHLLPRDPGDGGSVRENPSREHDGFFYALLGRQPA

Specific function: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA [H]

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=256, Percent_Identity=28.125, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI76150623, Length=256, Percent_Identity=28.125, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI301336155, Length=280, Percent_Identity=26.4285714285714, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI39995082, Length=305, Percent_Identity=25.5737704918033, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI11545785, Length=282, Percent_Identity=26.5957446808511, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI2367212, Length=411, Percent_Identity=38.1995133819951, Blast_Score=252, Evalue=3e-68,
Organism=Escherichia coli, GI87081985, Length=282, Percent_Identity=26.9503546099291, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17536757, Length=298, Percent_Identity=27.8523489932886, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI25143471, Length=182, Percent_Identity=32.4175824175824, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21355201, Length=220, Percent_Identity=30, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI22024126, Length=281, Percent_Identity=26.6903914590747, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: =2.1.1.176 [H]

Molecular weight: Translated: 49660; Mature: 49529

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: PS01153 NOL1_NOP2_SUN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPASSPHPSPSRPDSPGGAIPLWRQLDAVVDAVMAVRGGQSGTAALAAVDPVLRAGVQAL
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
FFAVLRQLGRAEALRAQLAPRRPKPRVDALLCSTLALGWQAGAAPYEPFTLVNQAVEAAK
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
RHAATRGQAAFVNACLRRFLRERDALVAATDSDPVARWNHPAWWIERLRKDHPGHWEQIL
HHHHCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHCCCCHHHHHH
RANNAQAPMALRIHRGKVDMAGYLAALEAVGMKAWPATDTGLVLESPQPVQRLPGFADGR
HCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCEEECCCCHHHHCCCCCCCC
VSVQDLAAQQAAPLLLSGLDLGRPLRVLDACAAPGGKTAHLLEYAGAGSPVHVTALEIDP
CCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHCCCCCCEEEEEEEECC
LRSARIGETLQRLGLRAQVLVADAGRPEDWWQQACGGEPFDAILLDAPCTASGIVRRHPD
CCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHCCCCCCCEEEEECCCCCCCHHHCCCC
VRWLRRPGDIAQLAAQQARLLSTLWPLLRPGGRMLYCTCSVFRAEGDDMVRSFLANNNDA
CHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEHHCCCHHHHHHHHCCCCCC
HLLPSPGHLLPRDPGDGGSVRENPSREHDGFFYALLGRQPA
EECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCC
>Mature Secondary Structure 
PASSPHPSPSRPDSPGGAIPLWRQLDAVVDAVMAVRGGQSGTAALAAVDPVLRAGVQAL
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
FFAVLRQLGRAEALRAQLAPRRPKPRVDALLCSTLALGWQAGAAPYEPFTLVNQAVEAAK
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
RHAATRGQAAFVNACLRRFLRERDALVAATDSDPVARWNHPAWWIERLRKDHPGHWEQIL
HHHHCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHCCCCHHHHHH
RANNAQAPMALRIHRGKVDMAGYLAALEAVGMKAWPATDTGLVLESPQPVQRLPGFADGR
HCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCEEECCCCHHHHCCCCCCCC
VSVQDLAAQQAAPLLLSGLDLGRPLRVLDACAAPGGKTAHLLEYAGAGSPVHVTALEIDP
CCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHCCCCCCEEEEEEEECC
LRSARIGETLQRLGLRAQVLVADAGRPEDWWQQACGGEPFDAILLDAPCTASGIVRRHPD
CCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHCCCCCCCEEEEECCCCCCCHHHCCCC
VRWLRRPGDIAQLAAQQARLLSTLWPLLRPGGRMLYCTCSVFRAEGDDMVRSFLANNNDA
CHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEHHCCCHHHHHHHHCCCCCC
HLLPSPGHLLPRDPGDGGSVRENPSREHDGFFYALLGRQPA
EECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]