| Definition | Acidovorax citrulli AAC00-1 chromosome, complete genome. |
|---|---|
| Accession | NC_008752 |
| Length | 5,352,772 |
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The map label for this gene is fabG [H]
Identifier: 120613145
GI number: 120613145
Start: 5011550
End: 5012317
Strand: Reverse
Name: fabG [H]
Synonym: Aave_4512
Alternate gene names: 120613145
Gene position: 5012317-5011550 (Counterclockwise)
Preceding gene: 120613146
Following gene: 120613144
Centisome position: 93.64
GC content: 72.01
Gene sequence:
>768_bases ATGAAGTTCAAGGGCCAGGTCGTTCTGGTGACGGGCGCGAGCCGGGGCATCGGCGCGGCCATCGCGCGGGCTTTCGCGCA GGAGGGCGCCACGGTGGTGGTGAACCATTTGTCCAACGACGCGGCGGCGGCCGAGACGGTGGCGGCCTGCCGCGCCGCCG GCGGCGATGCCTGGGCCGCGCGCGCCGACGTGGGCGATGCCGATGCGGTGCGCGCCATGGTGGACGCGGTGGTGCTGGAG GCCGGCCGCATCGACGTGGTGGTCAACAACGCTTTCCGGCCCTATGCCTTCGATGCACGGCGCCGCGCGCTGTTCGACGG CCTGCAGTGGAGCGACTACCAGGCCCAGTTCGACGGTGCCGTGGGCGGGGCCTTCAATGTCTGCCAGGCGGTGCTGCCGC ACCTGCGCCAGCGCGCGCGGGGCAGCGTCGTGAACATCGCCACCAACCTGGTGGAGCATCCGGTGGTGCCGTACCACGAC TACACCACGGCCAAGGCCGCGCTGGTGGCCTTCAGCCGCAACCTGGCGGCCGAGCTGGGGCCCGTGGGCATCCGCGTCAA TTGCGTGGCGCCGGGGCTGGTCTATCCCACGCAGGCGAGCCGATCCACGCCCGAGGCGCTGCGCGACGCGATCACCGCCG CCACGCCGCTGCGGCGCATCGCCCGGCCCGAGGATGTGGCGGGGCCGGTGCTGTTCCTGGCCTCGGAGTGGAGCAGCTTC ATGACCGGGCAGGTGCTGTTCGTCGATGGCGGGCTGGTGATGAAGTGA
Upstream 100 bases:
>100_bases TGGGCCTGGTGCAGCGCGACATCCGCGTGGCCGACGTGGTGGACGCCAGCCTGCTGCCCGCCGCGTGAGTCCGCCGGCCT TGAGGAGCGAGGAGCACCCC
Downstream 100 bases:
>100_bases CGGCGATGCCTGCTGCAGTGCGAGTGCGCGCATGACCCGCGTATGAATGGGCACGGGACGCCCAGGTGATTTGAAGTCGC GGGCGCTTTCGCTACAGTGC
Product: short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 255; Mature: 255
Protein sequence:
>255_residues MKFKGQVVLVTGASRGIGAAIARAFAQEGATVVVNHLSNDAAAAETVAACRAAGGDAWAARADVGDADAVRAMVDAVVLE AGRIDVVVNNAFRPYAFDARRRALFDGLQWSDYQAQFDGAVGGAFNVCQAVLPHLRQRARGSVVNIATNLVEHPVVPYHD YTTAKAALVAFSRNLAAELGPVGIRVNCVAPGLVYPTQASRSTPEALRDAITAATPLRRIARPEDVAGPVLFLASEWSSF MTGQVLFVDGGLVMK
Sequences:
>Translated_255_residues MKFKGQVVLVTGASRGIGAAIARAFAQEGATVVVNHLSNDAAAAETVAACRAAGGDAWAARADVGDADAVRAMVDAVVLE AGRIDVVVNNAFRPYAFDARRRALFDGLQWSDYQAQFDGAVGGAFNVCQAVLPHLRQRARGSVVNIATNLVEHPVVPYHD YTTAKAALVAFSRNLAAELGPVGIRVNCVAPGLVYPTQASRSTPEALRDAITAATPLRRIARPEDVAGPVLFLASEWSSF MTGQVLFVDGGLVMK >Mature_255_residues MKFKGQVVLVTGASRGIGAAIARAFAQEGATVVVNHLSNDAAAAETVAACRAAGGDAWAARADVGDADAVRAMVDAVVLE AGRIDVVVNNAFRPYAFDARRRALFDGLQWSDYQAQFDGAVGGAFNVCQAVLPHLRQRARGSVVNIATNLVEHPVVPYHD YTTAKAALVAFSRNLAAELGPVGIRVNCVAPGLVYPTQASRSTPEALRDAITAATPLRRIARPEDVAGPVLFLASEWSSF MTGQVLFVDGGLVMK
Specific function: 7-Alpha-Dehydroxylation Of Cholic Acid, Yielding Deoxycholic Acid And Lithocholic Acid, Respectively. Highest Affinity With Taurochenodeoxycholic Acid. [C]
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=255, Percent_Identity=33.3333333333333, Blast_Score=114, Evalue=8e-26, Organism=Homo sapiens, GI10190704, Length=253, Percent_Identity=32.8063241106719, Blast_Score=105, Evalue=5e-23, Organism=Homo sapiens, GI15277342, Length=262, Percent_Identity=33.969465648855, Blast_Score=102, Evalue=4e-22, Organism=Homo sapiens, GI19923817, Length=256, Percent_Identity=29.296875, Blast_Score=100, Evalue=2e-21, Organism=Homo sapiens, GI40254992, Length=249, Percent_Identity=32.5301204819277, Blast_Score=99, Evalue=3e-21, Organism=Homo sapiens, GI126723750, Length=252, Percent_Identity=30.5555555555556, Blast_Score=97, Evalue=1e-20, Organism=Homo sapiens, GI210032110, Length=194, Percent_Identity=30.9278350515464, Blast_Score=90, Evalue=3e-18, Organism=Homo sapiens, GI5031737, Length=248, Percent_Identity=30.241935483871, Blast_Score=87, Evalue=2e-17, Organism=Homo sapiens, GI4504505, Length=249, Percent_Identity=32.5301204819277, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI4758504, Length=259, Percent_Identity=28.1853281853282, Blast_Score=82, Evalue=5e-16, Organism=Homo sapiens, GI7705925, Length=265, Percent_Identity=29.0566037735849, Blast_Score=82, Evalue=6e-16, Organism=Homo sapiens, GI109715829, Length=256, Percent_Identity=28.90625, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI59889578, Length=245, Percent_Identity=29.7959183673469, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI66933014, Length=259, Percent_Identity=27.7992277992278, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI142976729, Length=194, Percent_Identity=28.8659793814433, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI126723191, Length=188, Percent_Identity=31.9148936170213, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI4503301, Length=255, Percent_Identity=27.4509803921569, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI83715985, Length=259, Percent_Identity=25.4826254826255, Blast_Score=65, Evalue=4e-11, Organism=Escherichia coli, GI1787905, Length=259, Percent_Identity=33.5907335907336, Blast_Score=128, Evalue=4e-31, Organism=Escherichia coli, GI1787335, Length=254, Percent_Identity=30.7086614173228, Blast_Score=120, Evalue=7e-29, Organism=Escherichia coli, GI87082100, Length=260, Percent_Identity=33.4615384615385, Blast_Score=120, Evalue=1e-28, Organism=Escherichia coli, GI1786812, Length=263, Percent_Identity=31.5589353612167, Blast_Score=109, Evalue=2e-25, Organism=Escherichia coli, GI1790717, Length=255, Percent_Identity=31.3725490196078, Blast_Score=108, Evalue=3e-25, Organism=Escherichia coli, GI2367175, Length=250, Percent_Identity=31.2, Blast_Score=108, Evalue=3e-25, Organism=Escherichia coli, GI1789208, Length=253, Percent_Identity=30.8300395256917, Blast_Score=100, Evalue=8e-23, Organism=Escherichia coli, GI1788459, Length=251, Percent_Identity=31.4741035856574, Blast_Score=100, Evalue=1e-22, Organism=Escherichia coli, GI1789378, Length=254, Percent_Identity=29.9212598425197, Blast_Score=89, Evalue=4e-19, Organism=Escherichia coli, GI2367365, Length=262, Percent_Identity=33.587786259542, Blast_Score=87, Evalue=8e-19, Organism=Escherichia coli, GI87082160, Length=257, Percent_Identity=26.4591439688716, Blast_Score=84, Evalue=9e-18, Organism=Escherichia coli, GI1787820, Length=231, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=2e-16, Organism=Escherichia coli, GI1789057, Length=266, Percent_Identity=26.6917293233083, Blast_Score=63, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17544670, Length=267, Percent_Identity=33.3333333333333, Blast_Score=122, Evalue=2e-28, Organism=Caenorhabditis elegans, GI17538480, Length=266, Percent_Identity=33.4586466165414, Blast_Score=103, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17560676, Length=250, Percent_Identity=30, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17561402, Length=259, Percent_Identity=30.5019305019305, Blast_Score=100, Evalue=8e-22, Organism=Caenorhabditis elegans, GI17560150, Length=275, Percent_Identity=31.6363636363636, Blast_Score=100, Evalue=9e-22, Organism=Caenorhabditis elegans, GI71994600, Length=261, Percent_Identity=32.5670498084291, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17565030, Length=271, Percent_Identity=31.3653136531365, Blast_Score=98, Evalue=5e-21, Organism=Caenorhabditis elegans, GI17559104, Length=273, Percent_Identity=29.3040293040293, Blast_Score=98, Evalue=5e-21, Organism=Caenorhabditis elegans, GI17562910, Length=276, Percent_Identity=27.8985507246377, Blast_Score=97, Evalue=6e-21, Organism=Caenorhabditis elegans, GI17562904, Length=275, Percent_Identity=30.1818181818182, Blast_Score=97, Evalue=6e-21, Organism=Caenorhabditis elegans, GI17551412, Length=270, Percent_Identity=32.2222222222222, Blast_Score=97, Evalue=7e-21, Organism=Caenorhabditis elegans, GI17560332, Length=268, Percent_Identity=32.8358208955224, Blast_Score=96, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17562990, Length=275, Percent_Identity=30.9090909090909, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17560220, Length=271, Percent_Identity=31.7343173431734, Blast_Score=94, Evalue=7e-20, Organism=Caenorhabditis elegans, GI193204405, Length=265, Percent_Identity=31.3207547169811, Blast_Score=94, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17555706, Length=253, Percent_Identity=28.8537549407115, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI25147288, Length=252, Percent_Identity=28.5714285714286, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI71994604, Length=259, Percent_Identity=33.976833976834, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17568967, Length=231, Percent_Identity=33.3333333333333, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17562906, Length=270, Percent_Identity=29.6296296296296, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17562908, Length=266, Percent_Identity=30.4511278195489, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI17536651, Length=256, Percent_Identity=27.34375, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI72000259, Length=265, Percent_Identity=29.0566037735849, Blast_Score=86, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17538486, Length=270, Percent_Identity=30.3703703703704, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI17531453, Length=271, Percent_Identity=30.2583025830258, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI115534694, Length=254, Percent_Identity=31.8897637795276, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17536025, Length=258, Percent_Identity=29.0697674418605, Blast_Score=81, Evalue=5e-16, Organism=Caenorhabditis elegans, GI17563726, Length=274, Percent_Identity=27.007299270073, Blast_Score=80, Evalue=8e-16, Organism=Caenorhabditis elegans, GI71982365, Length=201, Percent_Identity=31.3432835820896, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17561272, Length=239, Percent_Identity=28.0334728033473, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17538182, Length=263, Percent_Identity=28.1368821292776, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17508651, Length=260, Percent_Identity=24.6153846153846, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17508895, Length=193, Percent_Identity=26.9430051813472, Blast_Score=66, Evalue=1e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=256, Percent_Identity=31.25, Blast_Score=100, Evalue=2e-22, Organism=Saccharomyces cerevisiae, GI6322861, Length=244, Percent_Identity=29.5081967213115, Blast_Score=87, Evalue=3e-18, Organism=Saccharomyces cerevisiae, GI6322227, Length=207, Percent_Identity=27.536231884058, Blast_Score=74, Evalue=3e-14, Organism=Saccharomyces cerevisiae, GI6323882, Length=252, Percent_Identity=27.3809523809524, Blast_Score=68, Evalue=1e-12, Organism=Drosophila melanogaster, GI23397609, Length=261, Percent_Identity=35.2490421455939, Blast_Score=113, Evalue=1e-25, Organism=Drosophila melanogaster, GI21357041, Length=260, Percent_Identity=32.6923076923077, Blast_Score=100, Evalue=9e-22, Organism=Drosophila melanogaster, GI21355319, Length=256, Percent_Identity=28.125, Blast_Score=100, Evalue=1e-21, Organism=Drosophila melanogaster, GI24639444, Length=252, Percent_Identity=31.3492063492063, Blast_Score=99, Evalue=3e-21, Organism=Drosophila melanogaster, GI28571526, Length=259, Percent_Identity=32.8185328185328, Blast_Score=96, Evalue=3e-20, Organism=Drosophila melanogaster, GI24643142, Length=252, Percent_Identity=30.1587301587302, Blast_Score=94, Evalue=1e-19, Organism=Drosophila melanogaster, GI24644339, Length=263, Percent_Identity=29.277566539924, Blast_Score=89, Evalue=2e-18, Organism=Drosophila melanogaster, GI21357673, Length=201, Percent_Identity=31.8407960199005, Blast_Score=80, Evalue=1e-15, Organism=Drosophila melanogaster, GI18859837, Length=244, Percent_Identity=30.7377049180328, Blast_Score=80, Evalue=2e-15, Organism=Drosophila melanogaster, GI24644337, Length=260, Percent_Identity=29.2307692307692, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI281364892, Length=285, Percent_Identity=26.3157894736842, Blast_Score=71, Evalue=8e-13, Organism=Drosophila melanogaster, GI17737361, Length=265, Percent_Identity=26.4150943396226, Blast_Score=68, Evalue=5e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 26803; Mature: 26803
Theoretical pI: Translated: 8.08; Mature: 8.08
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 1.6 %Met (Translated Protein) 2.7 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 1.6 %Met (Mature Protein) 2.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKFKGQVVLVTGASRGIGAAIARAFAQEGATVVVNHLSNDAAAAETVAACRAAGGDAWAA CCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCCCEEE RADVGDADAVRAMVDAVVLEAGRIDVVVNNAFRPYAFDARRRALFDGLQWSDYQAQFDGA CCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCCHHHCCCC VGGAFNVCQAVLPHLRQRARGSVVNIATNLVEHPVVPYHDYTTAKAALVAFSRNLAAELG CCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCC PVGIRVNCVAPGLVYPTQASRSTPEALRDAITAATPLRRIARPEDVAGPVLFLASEWSSF CCCEEEEEECCCEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHH MTGQVLFVDGGLVMK HCCEEEEECCCEECC >Mature Secondary Structure MKFKGQVVLVTGASRGIGAAIARAFAQEGATVVVNHLSNDAAAAETVAACRAAGGDAWAA CCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCCCEEE RADVGDADAVRAMVDAVVLEAGRIDVVVNNAFRPYAFDARRRALFDGLQWSDYQAQFDGA CCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCCHHHCCCC VGGAFNVCQAVLPHLRQRARGSVVNIATNLVEHPVVPYHDYTTAKAALVAFSRNLAAELG CCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCC PVGIRVNCVAPGLVYPTQASRSTPEALRDAITAATPLRRIARPEDVAGPVLFLASEWSSF CCCEEEEEECCCEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHH MTGQVLFVDGGLVMK HCCEEEEECCCEECC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 10360571 [H]