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The map label for this gene is ttdR [H]

Identifier: 120613089

GI number: 120613089

Start: 4949983

End: 4950891

Strand: Reverse

Name: ttdR [H]

Synonym: Aave_4453

Alternate gene names: 120613089

Gene position: 4950891-4949983 (Counterclockwise)

Preceding gene: 120613093

Following gene: 120613085

Centisome position: 92.49

GC content: 73.93

Gene sequence:

>909_bases
ATGAAATTTGAAAATCTCTCCGACCTGCGCGTGCTGGTGGAGGCGGCGCGCGGGGGCTCGCTCACCGCCGCGGCCCGGGC
GCTGGACGTGACGCCTGCCGCGGCCAGCGCCATGCTCAAGCGGCTGGAGGCGCAGGTGGGCGTGCGCCTGTTCGAGCGCT
CCACGCGCGCACTGCGCATCACCGCCCAGGGCGGCACGCTGCTGGAATACGCCGAACGCGCGCTGGAATTGCTGGACGAG
GGCGCGGGCCTGGCCCAGAGCGAGACCGGCGCGCTGCGCGGCACCGTGCGCCTGGCCGCGCCCACCGATCTCTCGCGCGT
GCTGCTGCCGCGCCTAGACCGGTTCATGGAGCGGCACCCGGGCGTGCAACTGGCGCTGTCGGCCAGCGACCGCCTGCACG
ACGTGCGCCGCGATGCGGTGGACCTCGCCCTGCGCTACAGCGCGGAACTGCCGGATTCGCAACTCGTGGCCCGCGCGCTG
CACCACACCCGCCGCATCGCCTGCGCGGCACCGGAATACCTCGCGCGCCACGGCACCCCGCGGCACCCTTCGGAGCTGGC
GACGCACCGCTGCATCGCCATGGCCATCGCGGGCCGCCGCGAGGTGCGCTGGACCTTCGAGCGCGCGCCGGGCCATCCGC
CCGAGACCGTGGGCATCACCCTGCGCGCCGACCGCAGTGTGGACGACGGCGCCCTGGCCCACGCCTGGGCCCTGGCCGGC
GGGGGCATCGTCTACAAGTCGCGGCTGGACGTGCAGGCGCATCTGGACAGCGGGCAACTGGTGGAACTGCTGCCCGGGTG
GCTGGGGCAGGCATACACGGTGTACGCGGTGCTGCCGAGCCAGCGGTTCGTGCCCGCGCGGGTGCGGGCGCTGGTGGAGT
TCCTGGCGGAGGAATGGCGCCCCGGATGA

Upstream 100 bases:

>100_bases
CGGATCGCCCGGGATCGGTCGGGCGCCACGGAAGGGCTGCCCTGATTCTGGTGATTCAAAATGCGGTTGATAAGCCGCCA
GAAACCGCTATCACCTGCAA

Downstream 100 bases:

>100_bases
TGCCGGCGCGCCCGCCGGGTCACGCCCGGGCTTCGGCGAGCCGGAGGGCTTCCCGCGCCTTCAGCGTTTTCTTCACGGTG
CCCCAGATGGCCCATGCCAG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MKFENLSDLRVLVEAARGGSLTAAARALDVTPAAASAMLKRLEAQVGVRLFERSTRALRITAQGGTLLEYAERALELLDE
GAGLAQSETGALRGTVRLAAPTDLSRVLLPRLDRFMERHPGVQLALSASDRLHDVRRDAVDLALRYSAELPDSQLVARAL
HHTRRIACAAPEYLARHGTPRHPSELATHRCIAMAIAGRREVRWTFERAPGHPPETVGITLRADRSVDDGALAHAWALAG
GGIVYKSRLDVQAHLDSGQLVELLPGWLGQAYTVYAVLPSQRFVPARVRALVEFLAEEWRPG

Sequences:

>Translated_302_residues
MKFENLSDLRVLVEAARGGSLTAAARALDVTPAAASAMLKRLEAQVGVRLFERSTRALRITAQGGTLLEYAERALELLDE
GAGLAQSETGALRGTVRLAAPTDLSRVLLPRLDRFMERHPGVQLALSASDRLHDVRRDAVDLALRYSAELPDSQLVARAL
HHTRRIACAAPEYLARHGTPRHPSELATHRCIAMAIAGRREVRWTFERAPGHPPETVGITLRADRSVDDGALAHAWALAG
GGIVYKSRLDVQAHLDSGQLVELLPGWLGQAYTVYAVLPSQRFVPARVRALVEFLAEEWRPG
>Mature_302_residues
MKFENLSDLRVLVEAARGGSLTAAARALDVTPAAASAMLKRLEAQVGVRLFERSTRALRITAQGGTLLEYAERALELLDE
GAGLAQSETGALRGTVRLAAPTDLSRVLLPRLDRFMERHPGVQLALSASDRLHDVRRDAVDLALRYSAELPDSQLVARAL
HHTRRIACAAPEYLARHGTPRHPSELATHRCIAMAIAGRREVRWTFERAPGHPPETVGITLRADRSVDDGALAHAWALAG
GGIVYKSRLDVQAHLDSGQLVELLPGWLGQAYTVYAVLPSQRFVPARVRALVEFLAEEWRPG

Specific function: Positive regulator required for L-tartrate-dependent anaerobic growth on glycerol. Induces expression of the ttdA-ttdB- ygjE operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789440, Length=294, Percent_Identity=31.6326530612245, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI87081978, Length=295, Percent_Identity=33.2203389830508, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI145693193, Length=306, Percent_Identity=28.4313725490196, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1786401, Length=303, Percent_Identity=31.3531353135314, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1787128, Length=297, Percent_Identity=26.9360269360269, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1789639, Length=300, Percent_Identity=26, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1786448, Length=300, Percent_Identity=29.6666666666667, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1787589, Length=224, Percent_Identity=29.0178571428571, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789173, Length=260, Percent_Identity=31.5384615384615, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788706, Length=174, Percent_Identity=28.735632183908, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790011, Length=304, Percent_Identity=24.6710526315789, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI157672245, Length=143, Percent_Identity=32.8671328671329, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787601, Length=156, Percent_Identity=25.6410256410256, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32983; Mature: 32983

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFENLSDLRVLVEAARGGSLTAAARALDVTPAAASAMLKRLEAQVGVRLFERSTRALRI
CCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
TAQGGTLLEYAERALELLDEGAGLAQSETGALRGTVRLAAPTDLSRVLLPRLDRFMERHP
EECCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHCC
GVQLALSASDRLHDVRRDAVDLALRYSAELPDSQLVARALHHTRRIACAAPEYLARHGTP
CEEEEECCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCC
RHPSELATHRCIAMAIAGRREVRWTFERAPGHPPETVGITLRADRSVDDGALAHAWALAG
CCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEEEEEEECCCCCCCHHHHHHHHCC
GGIVYKSRLDVQAHLDSGQLVELLPGWLGQAYTVYAVLPSQRFVPARVRALVEFLAEEWR
CCEEEEEECCEEEECCCCCHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCC
PG
CC
>Mature Secondary Structure
MKFENLSDLRVLVEAARGGSLTAAARALDVTPAAASAMLKRLEAQVGVRLFERSTRALRI
CCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
TAQGGTLLEYAERALELLDEGAGLAQSETGALRGTVRLAAPTDLSRVLLPRLDRFMERHP
EECCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHCC
GVQLALSASDRLHDVRRDAVDLALRYSAELPDSQLVARALHHTRRIACAAPEYLARHGTP
CEEEEECCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCC
RHPSELATHRCIAMAIAGRREVRWTFERAPGHPPETVGITLRADRSVDDGALAHAWALAG
CCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEEEEEEECCCCCCCHHHHHHHHCC
GGIVYKSRLDVQAHLDSGQLVELLPGWLGQAYTVYAVLPSQRFVPARVRALVEFLAEEWR
CCEEEEEECCEEEECCCCCHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCC
PG
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]