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The map label for this gene is motA [H]

Identifier: 120613044

GI number: 120613044

Start: 4902509

End: 4903369

Strand: Direct

Name: motA [H]

Synonym: Aave_4408

Alternate gene names: 120613044

Gene position: 4902509-4903369 (Clockwise)

Preceding gene: 120613043

Following gene: 120613045

Centisome position: 91.59

GC content: 64.11

Gene sequence:

>861_bases
ATGTTCGTCATCATCGGTTACCTCGTCTGCCTGGGGTGCATCTTCGGGGTCTTCATCGCGCACGGCGGCAATATCTCCGT
GGTGCTGCACGCCCTGCCGTTCGAGATCGTCACGATTCTGGGCGGTGCCCTGGGCGCCTTCGTAGTGAACAACCAGCCCA
AGGTGCTGAAGGCCACGCTCAAGGCGCTGCCCATGGCGTTCAAGGGCTCCAAGTACACCAAGGCGCGTTACATGGAGCTG
ATGGCGATGCTCTACGAGATCCTGCAGAAGGCCCGCAAGGAAGGCCTGATGGCGATCGAGAAGGACGTGGAAGCGCCCCA
CGAGTCGGAAATCTTCAAGAAATACCCCACGGTGGGCACGGACCACCACGTGATCGAGTTCACCACCGACTACCTGCGCA
TGATGGTGTCGGGCAACCTGAACGCGCACGAGATCGAATCGCTCATGGACAGCGAGATCGAAACCCACCACCAGGAAGCC
CATGCCCCCGTGGCGGCCCTGGCCCGGCTGGCCGGCGCCCTGCCCGCCTTCGGCATCGTGGCCGCCGTGCTCGGGGTGGT
GAACACCATGGGCTCGGTGGGCCAGCCGCCCTCGGTGCTGGGCGGGATGATCGGCTCGGCCCTGGTGGGCACGTTCCTCG
GCATTCTGCTCGCCTACGGTGTGGTGGAGCCGCTGGGCGGCCTCGTGGAGCAGAAGCTCGAGGACGCCGCCAAGGAACTC
CAGTGCATCAAGACCACTCTGCTGGCCAGCATGCAGGGCTACAACCCCGCCACGGCCATCGAATTCGGCCGCAAGGTGCT
CTTCTCGGGCGACCGGCCCAGCTTCTCCGAACTGGAAAGCCACGTGAAGGGCAAGAAGTAA

Upstream 100 bases:

>100_bases
CCATTGACACGATGGATACGTTTCGTATCCGCCCCGCTGCCCCCACCGCTTCCAGAGGCGGTGGCCCTCTCCCACGCCCG
GCTCATCCGCACGCACCAGC

Downstream 100 bases:

>100_bases
CCCGGGCATCCGCCGGAGGTACACGCCATGGCCGACAAGAAGCTCCAGCCCATCATCATCAAGCGCGTCAAGAAGGGCGG
CCACGCCGCCCATGGCGGCG

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: Chemotaxis protein MotA [H]

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MFVIIGYLVCLGCIFGVFIAHGGNISVVLHALPFEIVTILGGALGAFVVNNQPKVLKATLKALPMAFKGSKYTKARYMEL
MAMLYEILQKARKEGLMAIEKDVEAPHESEIFKKYPTVGTDHHVIEFTTDYLRMMVSGNLNAHEIESLMDSEIETHHQEA
HAPVAALARLAGALPAFGIVAAVLGVVNTMGSVGQPPSVLGGMIGSALVGTFLGILLAYGVVEPLGGLVEQKLEDAAKEL
QCIKTTLLASMQGYNPATAIEFGRKVLFSGDRPSFSELESHVKGKK

Sequences:

>Translated_286_residues
MFVIIGYLVCLGCIFGVFIAHGGNISVVLHALPFEIVTILGGALGAFVVNNQPKVLKATLKALPMAFKGSKYTKARYMEL
MAMLYEILQKARKEGLMAIEKDVEAPHESEIFKKYPTVGTDHHVIEFTTDYLRMMVSGNLNAHEIESLMDSEIETHHQEA
HAPVAALARLAGALPAFGIVAAVLGVVNTMGSVGQPPSVLGGMIGSALVGTFLGILLAYGVVEPLGGLVEQKLEDAAKEL
QCIKTTLLASMQGYNPATAIEFGRKVLFSGDRPSFSELESHVKGKK
>Mature_286_residues
MFVIIGYLVCLGCIFGVFIAHGGNISVVLHALPFEIVTILGGALGAFVVNNQPKVLKATLKALPMAFKGSKYTKARYMEL
MAMLYEILQKARKEGLMAIEKDVEAPHESEIFKKYPTVGTDHHVIEFTTDYLRMMVSGNLNAHEIESLMDSEIETHHQEA
HAPVAALARLAGALPAFGIVAAVLGVVNTMGSVGQPPSVLGGMIGSALVGTFLGILLAYGVVEPLGGLVEQKLEDAAKEL
QCIKTTLLASMQGYNPATAIEFGRKVLFSGDRPSFSELESHVKGKK

Specific function: MotA and MotB comprise the stator element of the flagellar motor complex. Required for rotation of the flagellar motor. Probable transmembrane proton channel. Overexpression of MotA, with or without MotB, restores motility in a yhjH disruption, (a c-di-GM

COG id: COG1291

COG function: function code N; Flagellar motor component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MotA family [H]

Homologues:

Organism=Escherichia coli, GI1788199, Length=286, Percent_Identity=50.3496503496504, Blast_Score=312, Evalue=1e-86,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000540
- InterPro:   IPR022522
- InterPro:   IPR002898 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 30668; Mature: 30668

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: PS01307 MOTA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFVIIGYLVCLGCIFGVFIAHGGNISVVLHALPFEIVTILGGALGAFVVNNQPKVLKATL
CCHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
KALPMAFKGSKYTKARYMELMAMLYEILQKARKEGLMAIEKDVEAPHESEIFKKYPTVGT
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHCCCCCC
DHHVIEFTTDYLRMMVSGNLNAHEIESLMDSEIETHHQEAHAPVAALARLAGALPAFGIV
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCHHHHHH
AAVLGVVNTMGSVGQPPSVLGGMIGSALVGTFLGILLAYGVVEPLGGLVEQKLEDAAKEL
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QCIKTTLLASMQGYNPATAIEFGRKVLFSGDRPSFSELESHVKGKK
HHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCCC
>Mature Secondary Structure
MFVIIGYLVCLGCIFGVFIAHGGNISVVLHALPFEIVTILGGALGAFVVNNQPKVLKATL
CCHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
KALPMAFKGSKYTKARYMELMAMLYEILQKARKEGLMAIEKDVEAPHESEIFKKYPTVGT
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHCCCCCC
DHHVIEFTTDYLRMMVSGNLNAHEIESLMDSEIETHHQEAHAPVAALARLAGALPAFGIV
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCHHHHHH
AAVLGVVNTMGSVGQPPSVLGGMIGSALVGTFLGILLAYGVVEPLGGLVEQKLEDAAKEL
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QCIKTTLLASMQGYNPATAIEFGRKVLFSGDRPSFSELESHVKGKK
HHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 6090403; 9097040; 9278503; 3007435; 1719217; 7643400 [H]