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The map label for this gene is namA [H]

Identifier: 120611839

GI number: 120611839

Start: 3508531

End: 3510867

Strand: Reverse

Name: namA [H]

Synonym: Aave_3180

Alternate gene names: 120611839

Gene position: 3510867-3508531 (Counterclockwise)

Preceding gene: 120611840

Following gene: 120611838

Centisome position: 65.59

GC content: 69.88

Gene sequence:

>2337_bases
ATGAAGATCGTTTGCATCGGTGGCGGCCCGGCGGGCCTGTATTTCGCGCTGCTCATGAAGCAGCAGGACCCCGCCCACGA
CGTCACCGTGGTGGAGCGCAACAAGCCCTACGACACCTTCGGCTGGGGCGTGGTGTTTTCCGATGCCACCATGGACCACA
TGCGCGCCTGGGACCGCGAGACCGCCGACGAAATCCAGGAGGCCTTCAACCACTGGGACGACATCGAGCTGCGCTTCAAG
GGCCGCACGATCCGCTCGGGCGGGCACGGTTTCGTGGGCATCGGGCGCAAGAAGCTGCTCAATATCCTGCAGGCGCGCTG
CGAGCGCCTGGGCGTGAAGCTGGTGTTCGAGACCGAGGCCGCCTCCGACGAGGACTATCCCGACGCCGACCTCGTCATCG
CCTGCGACGGAGTGAACTCCCGCATCCGGGGCCGCTATGCCAACGTGTTCCAGCCCGACATCGTCACGCGGCCCAACCGC
TACATCTGGCTGGGCACGCACAAGCTGTTCGATGCCTTCACGTTCGACTTCCAGCGCACGGAGCATGGCTGGTTCCAGGC
ACACATCTACAAGTTCGACGACCGCACGACCACCTTCATCGTCGAGTGCCCGGAGGCGGTGTGGAAGGCGCACGGGCTGG
ACCAGGCCGACCAGGACCAGTCCATCGCCTTCTGCGAGCGCGTGTTCGCCGACACGCTGGGCGGCGCGCCCCTGATGAGC
AATGCGCGCCACCTGCGCGGCTCGGCCTGGCTGAACTTCCAGCGCGTGGTGTGCGCGCAATGGTGGCTGCGCAACCCCCG
CGGCAGCCACGTGGTGCTGATGGGCGACGCGGTGCACACGGCGCATTTCGCGATCGGCTCGGGCACCAAGCTCGCCATCG
AGGATGCGATCGAACTCGCGCGCCAGTTCGGCCGCCTGGGCGGTGGCCGCGAGGGCATTCCCGCCGTGCTCGCGGCCTAC
CAGGAGGCGCGCCGCGTGGAGACGCTGCGCATCCAGAACGCGGCCTGGAACGCGATGGAATGGTTCGAGGTGTGCGGAGA
CCGGTACTGCGACCAGCTGGAGCCCGAGCAGTTCATGTATTCGATGCTCACGCGCAGCCAGCGCATCAGCCACGAGAACC
TGCGCCTGCGCGATGCGGGCTGGCTGGAGGGCTACGAGCGCTGGTTCGCGCGCCGCGCGGGCATCGACGTGCCGGCCGGC
AGCCGGCCTCCGCCGCCCATGTTCACGCCGCTCACCGTGCGCGGCGCGACGCTCAAGAACCGCATCGTGGTCTCGCCCAT
GGCGCAGTATTCGGCGGAGGACGGCCTGGTGGGCGACTACCACCTGGTGCACCTGGGCGCGCGCGCCATGGGCGGTGCCG
GCCTCGTGTTCGCCGAGATGGCCTGCGTGAGCGCCGAAGGCCGCATCACCCCGGGCTGCCCGGGCCTGTACCGCCCCGGG
CACACGGCGGCCTTCCGCCGCATCGCCGACTGGATCCATGCGAACACCGACGCGAAGTTCGGCATCCAGATCGGCCATGC
GGGCGCCAAGGCCTCCACGCGCCGGGCCTGGGAGGGCATCGACCAGCCGCTGCCCGAGGGCAACTGGCCCATCATTTCCG
CCTCGCCGCAGCAGTACCTGGAAGGCGTGAGCCAGCGCGCGCGGCAGATGACCCGCGCCGACATGGATGCCGTGCGCGAG
CAGTTCGCCCAGGCCGCGCGCGCCGCCGATGCCGCGGGCGCCGACTGGCTGGAACTGCACTGCGCCCACGGCTACCTGCT
GTCGAGCTTTCTCTCGCCACTCACCAACCAGCGCGAAGACGAGTACGGCGGCCCGCTGGAGAACCGCCTGCGCTATCCGC
TGGAGGTGTTCGCCGCGGTGCGTGCCGCATGGCCGCAGGACAAGCCGCTGTCGGTGCGCATCTCCGCCCACGACTGGGTG
GAGGGCGGCACCACGCCGCAGGACGCGGTGGAGATCGCCCGGGCGTTCAAGGCCGCGGGCGCGGACATGATCGATTGTTC
CTCGGGCCAGGTGAGCAAGCGCGAGAAGCCGGTCTATGGCCGCATGTTCCAGACGCCGTTCGCCGACCGCATCCGGCAGG
AGGCTGGCATCGCCACCATCGCCGTCGGCGCCATCAGCGAGGCGGACCATGCCAACAGCATCCTGGCCGCCGGCCGGGCC
GACCTGTGCGCGGTGGCGCGGCCGCACCTGGCCAACCCGGCCTGGACGCTGGCGGAGGCCGCGCGCATCGGCTACACGGC
GGTGGATTGGCCGCGGCAGTACCGCTCCGGCAAGCAGCAGCTGGAGGCGCATTTCGAGCGCGAGAAATCCATGGCGGCGG
CGGGCGGGAAGGGCTGA

Upstream 100 bases:

>100_bases
TGCGCGTTTTCCCGGAGAAAGATGGCCCTTCAATTAGTTGACATCTAAATCATCTATTCCTAAAGTTGCCGCAGGCCCGG
ACGGCCCTGGAGACCTGCGC

Downstream 100 bases:

>100_bases
CGATGGACAAGACCCAACGGCATGCCCTGGTGACCGGCGGCACGCGCGGCATCGGCGCCGCCATCGCCCGGCGGCTCGTG
GCCGATGGCCTGCATGTGAC

Product: salicylyl-CoA 5-hydroxylase

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 778; Mature: 778

Protein sequence:

>778_residues
MKIVCIGGGPAGLYFALLMKQQDPAHDVTVVERNKPYDTFGWGVVFSDATMDHMRAWDRETADEIQEAFNHWDDIELRFK
GRTIRSGGHGFVGIGRKKLLNILQARCERLGVKLVFETEAASDEDYPDADLVIACDGVNSRIRGRYANVFQPDIVTRPNR
YIWLGTHKLFDAFTFDFQRTEHGWFQAHIYKFDDRTTTFIVECPEAVWKAHGLDQADQDQSIAFCERVFADTLGGAPLMS
NARHLRGSAWLNFQRVVCAQWWLRNPRGSHVVLMGDAVHTAHFAIGSGTKLAIEDAIELARQFGRLGGGREGIPAVLAAY
QEARRVETLRIQNAAWNAMEWFEVCGDRYCDQLEPEQFMYSMLTRSQRISHENLRLRDAGWLEGYERWFARRAGIDVPAG
SRPPPPMFTPLTVRGATLKNRIVVSPMAQYSAEDGLVGDYHLVHLGARAMGGAGLVFAEMACVSAEGRITPGCPGLYRPG
HTAAFRRIADWIHANTDAKFGIQIGHAGAKASTRRAWEGIDQPLPEGNWPIISASPQQYLEGVSQRARQMTRADMDAVRE
QFAQAARAADAAGADWLELHCAHGYLLSSFLSPLTNQREDEYGGPLENRLRYPLEVFAAVRAAWPQDKPLSVRISAHDWV
EGGTTPQDAVEIARAFKAAGADMIDCSSGQVSKREKPVYGRMFQTPFADRIRQEAGIATIAVGAISEADHANSILAAGRA
DLCAVARPHLANPAWTLAEAARIGYTAVDWPRQYRSGKQQLEAHFEREKSMAAAGGKG

Sequences:

>Translated_778_residues
MKIVCIGGGPAGLYFALLMKQQDPAHDVTVVERNKPYDTFGWGVVFSDATMDHMRAWDRETADEIQEAFNHWDDIELRFK
GRTIRSGGHGFVGIGRKKLLNILQARCERLGVKLVFETEAASDEDYPDADLVIACDGVNSRIRGRYANVFQPDIVTRPNR
YIWLGTHKLFDAFTFDFQRTEHGWFQAHIYKFDDRTTTFIVECPEAVWKAHGLDQADQDQSIAFCERVFADTLGGAPLMS
NARHLRGSAWLNFQRVVCAQWWLRNPRGSHVVLMGDAVHTAHFAIGSGTKLAIEDAIELARQFGRLGGGREGIPAVLAAY
QEARRVETLRIQNAAWNAMEWFEVCGDRYCDQLEPEQFMYSMLTRSQRISHENLRLRDAGWLEGYERWFARRAGIDVPAG
SRPPPPMFTPLTVRGATLKNRIVVSPMAQYSAEDGLVGDYHLVHLGARAMGGAGLVFAEMACVSAEGRITPGCPGLYRPG
HTAAFRRIADWIHANTDAKFGIQIGHAGAKASTRRAWEGIDQPLPEGNWPIISASPQQYLEGVSQRARQMTRADMDAVRE
QFAQAARAADAAGADWLELHCAHGYLLSSFLSPLTNQREDEYGGPLENRLRYPLEVFAAVRAAWPQDKPLSVRISAHDWV
EGGTTPQDAVEIARAFKAAGADMIDCSSGQVSKREKPVYGRMFQTPFADRIRQEAGIATIAVGAISEADHANSILAAGRA
DLCAVARPHLANPAWTLAEAARIGYTAVDWPRQYRSGKQQLEAHFEREKSMAAAGGKG
>Mature_778_residues
MKIVCIGGGPAGLYFALLMKQQDPAHDVTVVERNKPYDTFGWGVVFSDATMDHMRAWDRETADEIQEAFNHWDDIELRFK
GRTIRSGGHGFVGIGRKKLLNILQARCERLGVKLVFETEAASDEDYPDADLVIACDGVNSRIRGRYANVFQPDIVTRPNR
YIWLGTHKLFDAFTFDFQRTEHGWFQAHIYKFDDRTTTFIVECPEAVWKAHGLDQADQDQSIAFCERVFADTLGGAPLMS
NARHLRGSAWLNFQRVVCAQWWLRNPRGSHVVLMGDAVHTAHFAIGSGTKLAIEDAIELARQFGRLGGGREGIPAVLAAY
QEARRVETLRIQNAAWNAMEWFEVCGDRYCDQLEPEQFMYSMLTRSQRISHENLRLRDAGWLEGYERWFARRAGIDVPAG
SRPPPPMFTPLTVRGATLKNRIVVSPMAQYSAEDGLVGDYHLVHLGARAMGGAGLVFAEMACVSAEGRITPGCPGLYRPG
HTAAFRRIADWIHANTDAKFGIQIGHAGAKASTRRAWEGIDQPLPEGNWPIISASPQQYLEGVSQRARQMTRADMDAVRE
QFAQAARAADAAGADWLELHCAHGYLLSSFLSPLTNQREDEYGGPLENRLRYPLEVFAAVRAAWPQDKPLSVRISAHDWV
EGGTTPQDAVEIARAFKAAGADMIDCSSGQVSKREKPVYGRMFQTPFADRIRQEAGIATIAVGAISEADHANSILAAGRA
DLCAVARPHLANPAWTLAEAARIGYTAVDWPRQYRSGKQQLEAHFEREKSMAAAGGKG

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787939, Length=341, Percent_Identity=28.1524926686217, Blast_Score=113, Evalue=5e-26,
Organism=Escherichia coli, GI1789463, Length=331, Percent_Identity=27.190332326284, Blast_Score=105, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI17540738, Length=301, Percent_Identity=27.906976744186, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17559802, Length=143, Percent_Identity=37.7622377622378, Blast_Score=96, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17565138, Length=185, Percent_Identity=31.8918918918919, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17564188, Length=143, Percent_Identity=35.6643356643357, Blast_Score=92, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI72001454, Length=143, Percent_Identity=37.7622377622378, Blast_Score=90, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17559804, Length=143, Percent_Identity=37.0629370629371, Blast_Score=90, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17566914, Length=304, Percent_Identity=27.3026315789474, Blast_Score=87, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6321973, Length=242, Percent_Identity=28.5123966942149, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6325086, Length=218, Percent_Identity=27.9816513761468, Blast_Score=83, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 86382; Mature: 86382

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: PS00383 TYR_PHOSPHATASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIVCIGGGPAGLYFALLMKQQDPAHDVTVVERNKPYDTFGWGVVFSDATMDHMRAWDRE
CEEEEECCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCEEEECCCHHHHHHHHCHH
TADEIQEAFNHWDDIELRFKGRTIRSGGHGFVGIGRKKLLNILQARCERLGVKLVFETEA
HHHHHHHHHCCCCCEEEEEECEEEECCCCCEEECCHHHHHHHHHHHHHHCCEEEEEECCC
ASDEDYPDADLVIACDGVNSRIRGRYANVFQPDIVTRPNRYIWLGTHKLFDAFTFDFQRT
CCCCCCCCCCEEEEECCCCCHHCCCCCCCCCCCCEECCCCEEEEEHHHHHHHHHHHHHCC
EHGWFQAHIYKFDDRTTTFIVECPEAVWKAHGLDQADQDQSIAFCERVFADTLGGAPLMS
CCCEEEEEEEEECCCCEEEEEECCHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCHHC
NARHLRGSAWLNFQRVVCAQWWLRNPRGSHVVLMGDAVHTAHFAIGSGTKLAIEDAIELA
CHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEHEEEECCCCEEHHHHHHHHH
RQFGRLGGGREGIPAVLAAYQEARRVETLRIQNAAWNAMEWFEVCGDRYCDQLEPEQFMY
HHHHHCCCCCCCHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHH
SMLTRSQRISHENLRLRDAGWLEGYERWFARRAGIDVPAGSRPPPPMFTPLTVRGATLKN
HHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCC
RIVVSPMAQYSAEDGLVGDYHLVHLGARAMGGAGLVFAEMACVSAEGRITPGCPGLYRPG
EEEECCHHHCCCCCCCCCCCHHEEECHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCC
HTAAFRRIADWIHANTDAKFGIQIGHAGAKASTRRAWEGIDQPLPEGNWPIISASPQQYL
HHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCEEECCHHHHH
EGVSQRARQMTRADMDAVREQFAQAARAADAAGADWLELHCAHGYLLSSFLSPLTNQRED
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEHHHHHHHHHHHHHHHHCCCCC
EYGGPLENRLRYPLEVFAAVRAAWPQDKPLSVRISAHDWVEGGTTPQDAVEIARAFKAAG
CCCCCHHHHHCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCC
ADMIDCSSGQVSKREKPVYGRMFQTPFADRIRQEAGIATIAVGAISEADHANSILAAGRA
CCEEECCCCCCCCCCCCCHHHHHCCCHHHHHHHHCCEEEEEEECCCCCHHHHHHHHCCCC
DLCAVARPHLANPAWTLAEAARIGYTAVDWPRQYRSGKQQLEAHFEREKSMAAAGGKG
HHHHHCCCCCCCCHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKIVCIGGGPAGLYFALLMKQQDPAHDVTVVERNKPYDTFGWGVVFSDATMDHMRAWDRE
CEEEEECCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCEEEECCCHHHHHHHHCHH
TADEIQEAFNHWDDIELRFKGRTIRSGGHGFVGIGRKKLLNILQARCERLGVKLVFETEA
HHHHHHHHHCCCCCEEEEEECEEEECCCCCEEECCHHHHHHHHHHHHHHCCEEEEEECCC
ASDEDYPDADLVIACDGVNSRIRGRYANVFQPDIVTRPNRYIWLGTHKLFDAFTFDFQRT
CCCCCCCCCCEEEEECCCCCHHCCCCCCCCCCCCEECCCCEEEEEHHHHHHHHHHHHHCC
EHGWFQAHIYKFDDRTTTFIVECPEAVWKAHGLDQADQDQSIAFCERVFADTLGGAPLMS
CCCEEEEEEEEECCCCEEEEEECCHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCHHC
NARHLRGSAWLNFQRVVCAQWWLRNPRGSHVVLMGDAVHTAHFAIGSGTKLAIEDAIELA
CHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEHEEEECCCCEEHHHHHHHHH
RQFGRLGGGREGIPAVLAAYQEARRVETLRIQNAAWNAMEWFEVCGDRYCDQLEPEQFMY
HHHHHCCCCCCCHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHH
SMLTRSQRISHENLRLRDAGWLEGYERWFARRAGIDVPAGSRPPPPMFTPLTVRGATLKN
HHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCC
RIVVSPMAQYSAEDGLVGDYHLVHLGARAMGGAGLVFAEMACVSAEGRITPGCPGLYRPG
EEEECCHHHCCCCCCCCCCCHHEEECHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCC
HTAAFRRIADWIHANTDAKFGIQIGHAGAKASTRRAWEGIDQPLPEGNWPIISASPQQYL
HHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCEEECCHHHHH
EGVSQRARQMTRADMDAVREQFAQAARAADAAGADWLELHCAHGYLLSSFLSPLTNQRED
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEHHHHHHHHHHHHHHHHCCCCC
EYGGPLENRLRYPLEVFAAVRAAWPQDKPLSVRISAHDWVEGGTTPQDAVEIARAFKAAG
CCCCCHHHHHCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCC
ADMIDCSSGQVSKREKPVYGRMFQTPFADRIRQEAGIATIAVGAISEADHANSILAAGRA
CCEEECCCCCCCCCCCCCHHHHHCCCHHHHHHHHCCEEEEEEECCCCCHHHHHHHHCCCC
DLCAVARPHLANPAWTLAEAARIGYTAVDWPRQYRSGKQQLEAHFEREKSMAAAGGKG
HHHHHCCCCCCCCHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA