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The map label for this gene is yajO [H]

Identifier: 120611679

GI number: 120611679

Start: 3325655

End: 3326632

Strand: Direct

Name: yajO [H]

Synonym: Aave_3016

Alternate gene names: 120611679

Gene position: 3325655-3326632 (Clockwise)

Preceding gene: 120611678

Following gene: 120611683

Centisome position: 62.13

GC content: 67.89

Gene sequence:

>978_bases
ATGCAATCACGCCCCCTCGGCCGCTCCGGCCTGCAGGTTTCCCCGCTGTGCTTCGGCGGCAATGTGTTCGGCTGGACGGT
GGACGAGCCGACCACGTTCTCGCTGATCGACGCGTGGCTGGACGCGGGCTTCAACTTCATCGACACGGCCGATGTCTATT
CGCGCTGGAACCCGGGTCACATGGGGGGCGAATCCGAAGCCCTGATCGGCCAGTGGCTCAAGCGCACCGGCAAGCGGGAC
AGGATCGTGCTCGCCACCAAGGTGGGCAAGGACATGGGCGACGGCAGGGTCGGCCTGAAGCCGGACTACATCCGCCGCGC
GGTCGAGGATTCGCTGCGCCGCCTGCACACGGACTACATCGACCTCTACCAGTCGCACGACGACGATCCCTCCACGCCGC
TCGAGGACACGCTGGGCACCTATGCCGACCTGATCCGCGAAGGCAAGGTGCGCGCCATCGGCGCATCCAACCACACGGCC
GCCCGCCTGTCGGAAGCGCTCGCCACCAGCGCGCGGCTGGGCCTGCCGCGCTATGAATCGCTGCAGCCGCTCTACAACCT
GTACGACCGCGCGGTGTTCGAAGATGAATTGCAGCCGCTGTGCCTGGAGCAGCAGGTGGGCGTCATCAATTTCTACGCCC
TGGCCGCCGGCTTCCTCACAGGCAAGTACCGCAGCGAAGCCGACGCGTCCAAAAGCGCGCGCGGCGCCAAGACGGTGGAG
AAATACCTCAATCCGCGCGGCCTGCGCATCCTGGCCGAGCTCGACGAGGTGGCCGAGCGTTACGAGGCCACGCCCGGCCA
GGTCGCCATCGCATGGCAGATGGCCCAGCCCGCCATCACCGCGCCGATCGCCAGCGCGACCTCGCTGGAGCAGCTGCAGG
ACCTGGTGCGCGCCGCGCACCTGCAGCTCGACGCCGACGCACTGGAAGCGCTGAGCCAGGCCAGCGAGGAATCCCCCGAC
GAGGCTCGGCCCCTTTAA

Upstream 100 bases:

>100_bases
ATCTGACAGGTTCTTACAACTGCGCGGCCCGGGAGCCGTGCGGCGCCGCAACAATGGTCCGGAAGCCCGCCTTTCCCAAC
CAATCCAGGAGACTCCACCC

Downstream 100 bases:

>100_bases
CCGGCCAGGACGAAGGGCAGCACCCGCGCCGCCGTGCCGGGCACCAGCAGGTCCGCCACGCCGTCGAGCGCGCTGGGTTC
CGGATTGACGATGGCCACGC

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MQSRPLGRSGLQVSPLCFGGNVFGWTVDEPTTFSLIDAWLDAGFNFIDTADVYSRWNPGHMGGESEALIGQWLKRTGKRD
RIVLATKVGKDMGDGRVGLKPDYIRRAVEDSLRRLHTDYIDLYQSHDDDPSTPLEDTLGTYADLIREGKVRAIGASNHTA
ARLSEALATSARLGLPRYESLQPLYNLYDRAVFEDELQPLCLEQQVGVINFYALAAGFLTGKYRSEADASKSARGAKTVE
KYLNPRGLRILAELDEVAERYEATPGQVAIAWQMAQPAITAPIASATSLEQLQDLVRAAHLQLDADALEALSQASEESPD
EARPL

Sequences:

>Translated_325_residues
MQSRPLGRSGLQVSPLCFGGNVFGWTVDEPTTFSLIDAWLDAGFNFIDTADVYSRWNPGHMGGESEALIGQWLKRTGKRD
RIVLATKVGKDMGDGRVGLKPDYIRRAVEDSLRRLHTDYIDLYQSHDDDPSTPLEDTLGTYADLIREGKVRAIGASNHTA
ARLSEALATSARLGLPRYESLQPLYNLYDRAVFEDELQPLCLEQQVGVINFYALAAGFLTGKYRSEADASKSARGAKTVE
KYLNPRGLRILAELDEVAERYEATPGQVAIAWQMAQPAITAPIASATSLEQLQDLVRAAHLQLDADALEALSQASEESPD
EARPL
>Mature_325_residues
MQSRPLGRSGLQVSPLCFGGNVFGWTVDEPTTFSLIDAWLDAGFNFIDTADVYSRWNPGHMGGESEALIGQWLKRTGKRD
RIVLATKVGKDMGDGRVGLKPDYIRRAVEDSLRRLHTDYIDLYQSHDDDPSTPLEDTLGTYADLIREGKVRAIGASNHTA
ARLSEALATSARLGLPRYESLQPLYNLYDRAVFEDELQPLCLEQQVGVINFYALAAGFLTGKYRSEADASKSARGAKTVE
KYLNPRGLRILAELDEVAERYEATPGQVAIAWQMAQPAITAPIASATSLEQLQDLVRAAHLQLDADALEALSQASEESPD
EARPL

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=312, Percent_Identity=29.8076923076923, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI4504825, Length=309, Percent_Identity=29.7734627831715, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI27436964, Length=305, Percent_Identity=27.8688524590164, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI27436966, Length=305, Percent_Identity=27.8688524590164, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI27436962, Length=305, Percent_Identity=27.8688524590164, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI27436971, Length=330, Percent_Identity=28.7878787878788, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI223718702, Length=329, Percent_Identity=31.6109422492401, Blast_Score=101, Evalue=9e-22,
Organism=Homo sapiens, GI41152114, Length=222, Percent_Identity=36.9369369369369, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI41327764, Length=201, Percent_Identity=36.318407960199, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI223718708, Length=149, Percent_Identity=36.241610738255, Blast_Score=83, Evalue=4e-16,
Organism=Escherichia coli, GI87081735, Length=333, Percent_Identity=36.036036036036, Blast_Score=185, Evalue=3e-48,
Organism=Escherichia coli, GI1789199, Length=344, Percent_Identity=31.3953488372093, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1788070, Length=331, Percent_Identity=32.02416918429, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1789375, Length=308, Percent_Identity=29.2207792207792, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1788081, Length=295, Percent_Identity=29.4915254237288, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI48994888, Length=294, Percent_Identity=27.891156462585, Blast_Score=65, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6325169, Length=337, Percent_Identity=27.299703264095, Blast_Score=109, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6323998, Length=322, Percent_Identity=27.0186335403727, Blast_Score=101, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6319958, Length=298, Percent_Identity=26.8456375838926, Blast_Score=99, Evalue=7e-22,
Organism=Saccharomyces cerevisiae, GI6319951, Length=338, Percent_Identity=23.3727810650888, Blast_Score=84, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6321052, Length=163, Percent_Identity=34.3558282208589, Blast_Score=81, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6322615, Length=245, Percent_Identity=24.4897959183673, Blast_Score=66, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24646155, Length=233, Percent_Identity=32.618025751073, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24640980, Length=355, Percent_Identity=24.5070422535211, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI45549126, Length=350, Percent_Identity=24.2857142857143, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24646159, Length=182, Percent_Identity=31.3186813186813, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 35740; Mature: 35740

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSRPLGRSGLQVSPLCFGGNVFGWTVDEPTTFSLIDAWLDAGFNFIDTADVYSRWNPGH
CCCCCCCCCCCEECCEEECCCEEEEECCCCCHHHHHHHHHHCCCCCCCCHHHHHCCCCCC
MGGESEALIGQWLKRTGKRDRIVLATKVGKDMGDGRVGLKPDYIRRAVEDSLRRLHTDYI
CCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
DLYQSHDDDPSTPLEDTLGTYADLIREGKVRAIGASNHTAARLSEALATSARLGLPRYES
HHHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCHHH
LQPLYNLYDRAVFEDELQPLCLEQQVGVINFYALAAGFLTGKYRSEADASKSARGAKTVE
HHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHCCHHCHHHHHHHHCHHHHHH
KYLNPRGLRILAELDEVAERYEATPGQVAIAWQMAQPAITAPIASATSLEQLQDLVRAAH
HHCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHCHHHHHHHHHHHHHHHHHH
LQLDADALEALSQASEESPDEARPL
HCCCHHHHHHHHHHHCCCCHHCCCC
>Mature Secondary Structure
MQSRPLGRSGLQVSPLCFGGNVFGWTVDEPTTFSLIDAWLDAGFNFIDTADVYSRWNPGH
CCCCCCCCCCCEECCEEECCCEEEEECCCCCHHHHHHHHHHCCCCCCCCHHHHHCCCCCC
MGGESEALIGQWLKRTGKRDRIVLATKVGKDMGDGRVGLKPDYIRRAVEDSLRRLHTDYI
CCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
DLYQSHDDDPSTPLEDTLGTYADLIREGKVRAIGASNHTAARLSEALATSARLGLPRYES
HHHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCHHH
LQPLYNLYDRAVFEDELQPLCLEQQVGVINFYALAAGFLTGKYRSEADASKSARGAKTVE
HHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHCCHHCHHHHHHHHCHHHHHH
KYLNPRGLRILAELDEVAERYEATPGQVAIAWQMAQPAITAPIASATSLEQLQDLVRAAH
HHCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHCHHHHHHHHHHHHHHHHHH
LQLDADALEALSQASEESPDEARPL
HCCCHHHHHHHHHHHCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]